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  1. README.md +62 -2
README.md CHANGED
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- ---
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- quantized_by: bartowski
 
 
 
 
 
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  pipeline_tag: text-generation
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
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  ---
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  ## Llamacpp imatrix Quantizations of Palmyra-Med-70B-32K
 
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+ ---
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+ base_model: Writer/Palmyra-Med-70B-32K
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+ language:
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+ - en
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+ license: other
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+ license_name: writer-open-model-license
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+ license_link: https://writer.com/legal/open-model-license/
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  pipeline_tag: text-generation
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+ tags:
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+ - instruct
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+ - finetune
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+ - DPO
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+ - distillation
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+ - heathcare
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+ - medical
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+ - clinical
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+ - med
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+ - lifescience
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+ - Pharmaceutical
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+ - Pharma
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+ - Enterprise LLM
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+ - Enterprise
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+ - Enterprise ready
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+ quantized_by: bartowski
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+ extra_gated_prompt: By clicking "Agree", you agree to the [License Agreement](https://writer.com/legal/open-model-license/)
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+ and acknowledge Writer's [Privacy Policy](https://writer.com/legal/acceptable-use/).
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+ extra_gated_fields:
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+ Name: text
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+ Email: text
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+ Organization or Affiliation: text
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+ Receive email updates and promotions on Writer products, services, and research?:
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+ type: select
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+ options:
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+ - 'Yes'
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+ - 'No'
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+ I acknowledge that this model is for non-commercial use only unless I acquire a separate license from Writer: checkbox
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+ widget:
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+ - example_title: Palmyra-Med-70B-32k
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+ messages:
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+ - role: system
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+ content: You are a highly knowledgeable and experienced expert in the healthcare
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+ and biomedical field, possessing extensive medical knowledge and practical expertise.
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+ - role: user
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+ content: Does danzhi Xiaoyao San ameliorate depressive-like behavior by shifting
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+ toward serotonin via the downregulation of hippocampal indoleamine 2,3-dioxygenase?
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+ output:
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+ text: Danzhi Xiaoyao San (DXS) exhibited significant antidepressant-like effects
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+ in rats subjected to chronic unpredictable mild stress (CUMS), a commonly used
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+ model for inducing depressive-like behavior. The administration of DXS led to
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+ a notable reduction in the activity of indoleamine 2,3-dioxygenase (IDO) in
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+ the hippocampus. This reduction in IDO activity is crucial because IDO is an
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+ enzyme that catalyzes the degradation of tryptophan into kynurenine (Kyn), thereby
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+ diverting tryptophan away from the serotonin (5-HT) synthesis pathway. By downregulating
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+ IDO, DXS effectively shifts the balance of tryptophan metabolism towards increased
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+ serotonin production, thereby enhancing the availability of serotonin. This
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+ shift in the Kyn/5-HT pathway favoring serotonin is likely a key mechanism underlying
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+ the antidepressant effects observed with DXS treatment. Enhanced serotonin levels
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+ in the hippocampus are associated with improved mood and reduction of depressive
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+ symptoms, suggesting that DXS could be a promising therapeutic agent for managing
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+ depression.
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+ model-index:
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+ - name: Palmyra-Med-70B-32k
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+ results: []
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  ---
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  ## Llamacpp imatrix Quantizations of Palmyra-Med-70B-32K