Question: are cardiac complications likely in patients with COVID-19?

The passage discusses the use of cardiac biomarkers to triage, risk-stratify, and prognosticate patients with severe COVID-19. COVID-19 is associated with acute cardiac injury in 7-28% of patients, leading to increased complications and mortality, especially in those with underlying cardiovascular disease. Cardiac biomarkers can help differentiate cardiac causes of dyspnea and aid in clinical decision-

The COVID-19 pandemic has highlighted the connection between the disease and cardiovascular risks. The virus, SARS-CoV2, enters cells through ACE2 receptors in select organs. Epidemiological evidence suggests that cardiovascular risk factors increase disease severity and mortality in COVID-19 patients, and those with severe COVID-19 are more likely to develop cardiac complications like myocardial injury and arrhythmia. The underlying

The passage discusses the connection between Cardiovascular diseases and COVID-19. The virus, SARS-CoV2, enters cells through ACE2 expressed in certain organs. Epidemiological evidence suggests that cardiovascular risk factors increase disease severity and mortality in COVID-19 patients, and those with severe COVID-19 are more likely to develop cardiac complications like myocardial injury and arrhythmia. The true incidence and mechanisms

A meta-analysis of 56 studies on COVID-19 patients found that high cardiac troponin I and AST levels were associated with increased odds of adverse outcomes. The best model to predict poor outcomes was a combination of high troponin I >13.75 ng/L and either advanced age >60 years or elevated AST level >27.72 U/L. Assessment of cardiac injury biomarkers may help identify

A meta-analysis of 56 studies on COVID-19 patients (n=17,794) found that high cardiac troponin I and aspartate aminotransferase levels were associated with increased odds of adverse outcomes (OR = 5.22, 95% CI = 3.73-7.31 for troponin I and OR = 3.64, 95% C

The coronavirus disease-2019 (COVID-19) has spread to over 100 countries with over 1 million confirmed cases. While it primarily causes severe respiratory infections, cardiac complications and poor outcomes have been observed in patients, particularly those with underlying cardiovascular disease. This passage discusses the potential mechanisms of cardiac complications in COVID-19 patients and emphasizes the importance of supportive therapy and identifying high-risk individuals before

A retrospective study of 113 deceased and 161 recovered patients with COVID-19 at Tongji Hospital in Wuhan, China, found that deceased patients were older (median age 68 years vs. 51 years), more likely male (73% vs. 55%), and had more chronic hypertension and cardiovascular comorbidities (48% and 14% vs. 24

COVID-19, caused by the SARS-CoV-2 virus, typically presents as mild flu-like illness but can lead to severe disease and neurological complications in elderly patients with comorbidities. Neurological manifestations include central and peripheral nervous system involvement, with potential entry points being the hematogenous route or olfactory system. Severe neurological symptoms, such as altered sensorium and stroke, are due to hypoxia,

COVID-19, caused by the SARS-CoV-2 virus, can lead to neurological complications, particularly in severely ill patients with comorbidities. Both central and peripheral nervous systems can be affected. The virus enters the brain through the hematogenous route or olfactory system, using angiotensin-converting enzyme two receptors as entry points. Severe neurological manifestations include altered sensorium, cyt

The SARS-CoV-2 infection can cause cardiac events that require prompt diagnosis and management, even in the presence of COVID-19. Due to logistical challenges, a full cardiovascular disease diagnostic algorithm may be hindered in patients with critical conditions. Echocardiography can help with differential diagnosis of cardiac events related or unrelated to the infection and can impact short-term prognosis. Focused cardiac ultrasound studies (FoC

The SARS-CoV-2 pandemic can lead to cardiac events that require prompt diagnosis and management, even in the presence of COVID-19 infection. Logistical challenges may hinder a full cardiovascular disease diagnostic algorithm in critical patients. Echocardiography, specifically focused bedside transthoracic studies (FoCUS), can aid in differential diagnosis of cardiac events related or unrelated to COVID-19 and impact short-term progn

A case is presented of a patient who developed unusually rapid pulmonary hypertension and right ventricular failure after severe COVID-19 pneumonia and cytokine release syndrome. These complications, which may be caused by progressive pulmonary parenchymal and microvascular damage, have not been described before in relation to COVID-19. COVID-19 is associated with systemic and multi-organ involvement, including vascular, thrombo

During the COVID-19 pandemic, patients with pre-existing cardiovascular conditions and risk factors face higher risks of adverse outcomes. Additionally, new cardiac complications, such as myocarditis, arrhythmia, and heart failure, are emerging in patients without prior cardiovascular issues. The healthcare system is overwhelmed with COVID-19 cases, leaving an unmet need for managing both COVID-19 related and traditional cardiovascular issues. This passage offers consensus guidance for

During the COVID-19 pandemic, patients with pre-existing cardiovascular conditions and those experiencing new cardiac complications are at higher risk. The pandemic has led to an increase in cardiac injuries and de novo cardiac complications, possibly due to an accentuated immune response. With many patients requiring medical care for both COVID-19 related and traditional cardiovascular issues, there is a need for a standardized approach. This passage provides consensus guidance for managing various cardiovascular

The coronavirus disease 2019 (COVID-19) has spread to over 100 countries and affected over 1 million people. While the primary symptom is severe respiratory infection, accumulating data shows that cardiac complications and poor outcomes are common among patients, particularly those with underlying cardiovascular disease. This article reviews the basics of the virus, clinical manifestations, and potential mechanisms of cardiac complications in COVID-19 patients.

The passage discusses the cardiac implications of COVID-19, highlighting the increased risk of cardiac involvement for patients with pre-existing cardiovascular disease and higher mortality rates. The review also mentions various cardiac presentations such as acute pericarditis, left ventricular dysfunction, and acute myocardial injury. There is a lack of data on myocardial protection during cardiac surgery for COVID-19 patients. While some insights

The SARS-CoV-2 pandemic necessitates significant adjustments in cardiology practice. This article discusses managing cardiac patients without COVID-19, those with cardiac disease and COVID-19, and cardiac complications of COVID-19. It also covers indications and interpretation of cardiac investigations in the context of the pandemic, with references from specialized societies and groups.

The SARS-CoV-2 pandemic necessitates significant adjustments in cardiology practice. This article discusses managing cardiac patients without COVID-19, those with cardiac disease and COVID-19, and cardiac complications of COVID-19. It also covers indications and interpretation of cardiac investigations in the context of COVID-19, with references from specialized societies and groups.

The passage discusses the investigation of acute myocardial injury (AMI) in 53 hospitalized Coronavirus Disease 2019 (COVID-19) patients. Of these patients, 42 (79.25%) had cardiac complications, including six cases of AMI. All AMI patients were over 60 years old and had multiple underlying comorbidities. The severity of novel coronavirus pneumonia

People with epilepsy are not more susceptible to COVID-19 or more likely to have severe manifestations. However, managing COVID-19 in those with epilepsy can be complicated due to potential drug-drug interactions between antiepileptic drugs and COVID-19 treatments, as well as the possibility of cardiac, hepatic, or renal issues in severe COVID-19 cases that may require AED adjustments. This review discusses potential drug

The passage discusses the cardiac and arrhythmic complications associated with COVID-19, caused by a multifactorial etiology including direct viral damage, hypoxia, hypotension, inflammation, drug toxicity, and endogenous catecholamine status. Patients with COVID-19 and cardiac injury markers have poorer outcomes, and arrhythmic events are common. Additionally, drugs used to treat COVID-19 can

The passage discusses the cardiac and arrhythmic complications associated with COVID-19, the cause of which is believed to be multifactorial including direct viral damage, hypoxia, hypotension, inflammation, and drug toxicity. Patients with COVID-19 who exhibit cardiac injury markers have poorer outcomes and arrhythmic events are common. Additionally, drugs used to treat COVID-19 can prolong the QT interval and have a

The COVID-19 pandemic and containment measures have led to a significant decrease in acute cardiovascular disease admissions in France, according to a study of nine major cardiology centers. Before containment, an average of 4.8 patients per day were admitted to intensive care units for acute myocardial infarction or acute heart failure. After containment, this number dropped to 2.6 patients per day, a difference that was statistically significant

A study conducted in France found that the number of cardiovascular admissions to intensive care units significantly decreased after the implementation of COVID-19 containment measures. The drop was from 4.8 to 2.6 patients per day, raising concerns about neglected acute cardiovascular diseases due to prioritization of COVID-19 resources. Potential consequences include an increase in ambulatory myocardial infarctions, mechanical complications, cardiac arrest

Three cases of cardiac complications in COVID-19 patients are presented. A 67-year-old woman with non-ischaemic dilated cardiomyopathy developed viral pericarditis and Takotsubo syndrome. A 46-year-old man with obesity and type 2 diabetes mellitus experienced pulseless electrical activity arrest and suspected STEMI due to microemboli, resulting in death. A 76

The passage discusses the cardiovascular complications of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) and their impact on clinical outcomes. SARS-CoV-2 damages the heart through ACE-2 receptors, causing direct damage to cardiomyocytes, systemic inflammation, fibrosis, and hypoxia. Comorbidities, particularly underlying heart disease, increase

A 63-year-old male with COVID-19 developed pneumonia, cardiac symptoms, and fulminant myocarditis, marked by elevated troponin I levels, decreased left ventricular ejection fraction, and diffuse myocardial dyskinesia. The patient met the diagnostic criteria for fulminant myocarditis and received antiviral therapy and mechanical life support, resulting in reduced troponin I and interleuk

COVID-19 infection can lead to various cardiac complications with significant adverse outcomes. The utility of cardiac imaging in hospitalized COVID-19 patients depends on the clinical scenario and the potential risks to healthcare workers. Cardiac imaging should be ordered only if its benefits exceed the risks, and no adequate alternative is available. Indications for advanced cardiac imaging in the acute phase are limited, but follow-up imaging in the convalescent stage may be

The Coronavirus disease caused by SARS-CoV-2, which emerged in Wuhan, China in late 2019, has resulted in over 2.3 million confirmed cases and 165,000 fatalities worldwide. While the primary symptoms are respiratory and cardiac, neurological manifestations are also being reported. Common neurological symptoms include headache, dizziness, encephalopathy, and delir

The Coronavirus disease caused by SARS-CoV-2, with over 3.5 million confirmed cases and 165,000 to 243,000 fatalities, primarily manifests as respiratory and cardiac issues but neurological symptoms such as headache, dizziness, encephalopathy, delirium, cerebrovascular accident, Guillian-Barre syndrome, acute transverse

The COVID-19 pandemic is putting significant strain on healthcare systems and increasing risk for complications and mortality among COVID-19 patients with cardiac risk factors or pre-existing heart conditions. The involvement of the heart in COVID-19 is becoming clear, whether through direct myocardial infection and damage or cardiac complications.

The COVID-19 pandemic, affecting over 5.5 million cases in 215 countries, has been linked to various cardiac manifestations. A systematic review of 61 articles identified risk factors, cardiac manifestations (heart failure, cardiogenic shock, arrhythmia, myocarditis), and cardiac-specific biomarkers (CK-MB, CK, myoglobin, troponin, NT-proBNP).

The passage is a systematic review of studies on cardiac manifestations and biomarkers in COVID-19 patients. Sixty-one relevant articles were identified, which discussed risk factors for cardiovascular complications, various cardiac manifestations (such as heart failure, cardiogenic shock, arrhythmia, and myocarditis), and the use of cardiac-specific biomarkers (including CK-MB, CK, myoglobin

A case is presented of a patient with severe COVID-19 pneumonia who developed acute life-threatening cardiac tamponade caused by a small pericardial effusion. The patient experienced circulatory collapse with features of cardiogenic or obstructive shock. Diagnosis was made through bedside echocardiography, leading to life-saving pericardiocentesis. No other cause of pericardial effusion was found except

The study aimed to investigate the clinical characteristics, laboratory findings, and HRCT features of 132 COVID-19 patients with diabetes in Wuhan, China, and explore risk factors for in-hospital death and complications. Patients with an admission glucose level of >11mmol/L were more likely to require ICU care, develop ARDS and acute cardiac injury, and had a higher death rate than those with an admission glucose level of

The study aimed to investigate the clinical characteristics, laboratory findings, and HRCT features of 132 COVID-19 patients with diabetes in Wuhan China, and to explore risk factors for in-hospital death and complications. Patients with an admission glucose level >11mmol/L were more likely to require ICU care, develop ARDS and acute cardiac injury, and had a higher death rate than those with an admission glucose level <1

A 53-year-old woman with COVID-19 developed acute myopericarditis a week after recovering from upper respiratory symptoms. She presented with severe fatigue, hypotension, and ST elevation on EKG, along with elevated levels of NT-proBNP and troponin T. Chest radiography was normal, and coronary angiography showed no obstructive coronary disease. Cardiac magnetic resonance imaging

A case is presented of a patient with COVID-19 who developed acute viral pericarditis and cardiac tamponade, highlighting the challenges in treatment due to safety uncertainties and potential complications of delayed diagnosis, particularly in intubated patients. Key takeaways include the consideration of large pericardial effusions and cardiac tamponade in COVID-19 patients who deteriorate after intubation and mechanical ventilation, the description of

This study examined the relationship between hypertension and COVID-19, as well as the impact of prior use of renin-angiotensin-aldosterone system (RAAS) inhibitors on the prognosis of COVID-19 patients. The study included 996 COVID-19 patients, 282 of whom had hypertension. Patients with hypertension had more severe secondary infections, cardiac and renal dysfunction, and

SARS-CoV-2 causes COVID-19 with symptoms ranging from mild to severe, including cardiac complications such as myocardial injury, arrhythmias, cardiogenic shock, and sudden death. Drug interactions with COVID-19 treatments may also lead to arrhythmias, cardiomyopathy, and sudden death. This review outlines the cardiac manifestations of COVID-19 infection and suggests a simplified algorithm for patient management during the

A systematic review and meta-analysis of studies from November 1, 2019 to June 7, 2020 found that COVID-19 patients with underlying cardiovascular disease, specifically congestive heart failure (CHF), and elevated cardiac biomarkers had increased risk of acute cardiac injury, arrhythmias, and mortality. The pooled data from 20 studies included 5,967 COVID-19

COVID-19, a global pandemic causing primary respiratory symptoms, also leads to severe cardiac complications including arrhythmias, myocardial infarction, myocarditis, myocardial injury, and heart failure. Severe cases can result in circulatory failure. This review emphasizes a "Heart-Lung" team approach for managing patients with severe cardiac complications of COVID-19 and discusses the use and indications for acute

COVID-19, a global pandemic causing primary respiratory symptoms, also leads to severe cardiac complications including arrhythmias, myocardial infarction, myocarditis, myocardial injury, and heart failure. Severe cases can result in circulatory failure. This review focuses on managing patients with severe cardiac complications using a Heart-Lung team approach and the use of acute mechanical circulatory support for cardiogenic and/or mixed

During the COVID-19 pandemic in New York City from March 1 to April 25, 2020, there was a significant increase in out-of-hospital cardiac arrests, with 3 times the incidence compared to the same period in 2019. Patients with out-of-hospital cardiac arrest during 2020 were older, less white, and had higher rates of hypertension, diabetes, and physical

This meta-analysis aimed to evaluate the prevalence of symptoms and complications of COVID-19 based on 30 studies with 6,389 infected patients. The most common symptoms were fever (84.30%), cough (63.01%), dyspnea (37.16%), fatigue (34.22%), and diarrhea (11.47%). The most prevalent complications were

The Indian Resuscitation Council (IRC) has issued guidelines for managing comprehensive cardiopulmonary life support (CCLS) for suspected or confirmed COVID-19 patients due to the unique challenges posed by the virus. Older individuals with comorbidities are more vulnerable to COVID-19 and have a higher mortality rate. The IRC previously proposed CCLS for hospital settings, but modifications are necessary for COVID-19 patients due to differing causes of

During the COVID-19 pandemic in Ontario, a directive was issued to halt nonessential cardiac procedures due to the potential need for resources for critically ill COVID-19 patients. A decision analytic model called the COVID-19 Resource Estimator (CORE) was adapted to determine the impact of policy decisions on cardiac patients' waitlists and mortality. In the initial crisis phase, the number of waitlist-related cardiac deaths was predicted to be much less

During the COVID-19 pandemic in Ontario, a directive was issued to halt non-essential cardiac procedures due to the potential need for resources for critically ill COVID-19 patients. A decision analytic model called the COVID-19 Resource Estimator (CORE) was adapted to estimate the impact of various policy decisions on waitlist growth and mortality for three cardiovascular disease patient groups. In the initial crisis phase, the number of waitlist-related cardiac

A directive was issued in Ontario on March 16, 2020, to halt non-essential cardiac procedures due to the anticipated surge in COVID-19 patients requiring intensive care units, ventilators, and critical care personnel. A decision analytic model called the COVID-19 Resource Estimator (CORE) was adapted with a cardiac component to determine the impact of policy decisions on waitlist growth and mortality for coronary artery disease,

The COVID-19 pandemic has significantly impacted critical care cardiology due to the disease's respiratory, renal, and cardiovascular complications. The cardiac intensive care unit (CICU) is adapting to the increasing need for critical care beds. This article discusses changes to the CICU, the evolving role of critical care cardiologists, and practical recommendations for structural and organizational changes, staffing, and personnel safety during the

COVID-19, caused by SARS-CoV-2, has become a global health emergency with respiratory illness as the primary symptom. The disease can lead to cardiomyopathy, cardiac dysfunction, and heart failure due to disruption of Angiotensin Converting Enzyme-2 receptors. Patients with preexisting cardiovascular conditions, such as hypertension, arrhythmia, cardiomyopathy

COVID-19, caused by SARS-CoV-2, has become a global health emergency with respiratory illness being the primary cause of morbidity and mortality. The disease spectrum ranges from asymptomatic to severe pneumonia and acute respiratory distress syndrome. SARS-CoV-2 uses Angiotensin Converting Enzyme-2 receptors for entry into cells, and disruption of these receptors can lead

The passage discusses the current understanding of cardiovascular complications in patients with COVID-19. The purpose of the review is to explore the potential mechanisms of myocardial injury due to viral toxicities and host immune responses. Recent findings suggest an association between pre-existing cardiac disease and worsened outcomes during COVID-19 infection, as well as increased mortality from new onset myocardial injury. Potential mechanisms of cardiac injury include direct viral

COVID-19, caused by SARS-CoV-2, is linked to increased cardiac injury and mortality. Potential mechanisms include viral entry through ACE2 receptors, host cell toxicity, hypoxia, and immune responses. Further research is required to understand the mechanisms and effective treatments. Patients with cardiac disease history or new cardiac injury face higher in-hospital risks.

A systematic review and network meta-analysis of 49 studies with 20,212 confounder-adjusted patients evaluated the comparative efficacy and safety of various pharmacological interventions for COVID-19. Tocilizumab, anakinra, and remdesivir reduced the risk of severe pneumonia or ICU admission and mortality in hospitalized patients. High-dose IVIG reduced mortality, while cortic

The SARS-CoV-2 virus, which causes COVID-19, is spreading globally and affecting millions of people. While information about the disease is rapidly evolving, there is uncertainty regarding optimal management strategies for critically ill patients. These patients may develop severe forms of the disease with expanding pulmonary lesions, sepsis, acute respiratory distress syndrome, and respiratory failure. Due to a lack of specific data on treatment strategies for this subset of

The SARS-CoV-2 infection, which causes COVID-19, is linked to acute myocardial injury, cardiomyopathy, and myocarditis. Individuals with myocardial involvement may experience severe illness. Cardiomyopathies are diseases of the heart muscle, characterized by mechanical and/or electrical dysfunction, and can be genetic, mixed, or acquired. The high inflammatory response in COVID-19 patients with

A study of 700 COVID-19 patients in a large urban hospital found an association between the disease and various arrhythmias, including atrial fibrillation, bradyarrhythmias, and nonsustained ventricular tachycardia. Cardiac arrests occurred only among ICU patients and were linked to increased risk of arrhythmias and mortality. Age, ICU admission, and prevalent heart failure were independent risk factors for arrhythmias.

A study of 700 COVID-19 patients in a large urban hospital found an association between the disease and various arrhythmias, including atrial fibrillation, bradyarrhythmias, and nonsustained ventricular tachycardia. Cardiac arrests occurred only among ICU patients and were linked to increased risk of arrhythmias and mortality. Factors like age, ICU admission, and prevalent heart conditions were independent risk factors for

This study analyzed over thirteen million adverse event reports from the US Food and Drug Administration to confirm the association of cardiac side effects with the use of chloroquine and hydroxychloroquine. The drugs, which are on the World Health Organization's List of Essential Medications, have been used for treating non-resistant malaria, rheumatoid arthritis, and systemic lupus erythematosus, as well

Coronavirus disease 2019 (COVID-19) is caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). Common symptoms include fever, cough, myalgia, fatigue, expectoration, and dyspnea. Laboratory abnormalities include decreased lymphocyte count, thrombocytopenia, elevated C-reactive protein, lact

The passage discusses the uncertain mechanisms of cardiac injury in COVID-19 patients, with evidence of a correlation between cardiac injury biomarker troponin T and inflammation marker C-reactive protein. Common mechanisms of myocardial tissue damage include acute myocarditis, ACE2 receptor binding, cytokine secretion, and hypoxia-induced apoptosis. Prospective histopathological studies are necessary for proper treatment

Three patients with COVID-19 at Northwell Plainview Hospital in New York experienced arterial vascular complications despite prophylaxis, including one with a cerebrovascular accident, another with popliteal artery occlusion, and the third with both. While respiratory complications of COVID-19 are well-documented, non-respiratory complications, such as arterial thromboembolic events, have been limited in

The passage discusses the uncertain mechanisms of cardiac injury in patients with COVID-19, highlighting the correlation between cardiac injury biomarker troponin T and inflammation marker C-reactive protein. Common mechanisms of myocardial tissue damage include acute myocarditis, ACE2 receptor binding, cytokine secretion, and hypoxia-induced apoptosis. Elucidating disease pathogenesis and conducting histopath

The passage discusses the impact of COVID-19 on the cardiovascular system, particularly in severe cases. Cardiovascular risk factors and conditions are common among COVID-19 patients and linked to unfavorable outcomes. The relationship between pre-existing cardiovascular disease and higher mortality risk with COVID-19 is uncertain. Acute cardiac injury, which can be identified through increased cardiac troponin levels, electrocardiographic abnormalities, or myocard

The COVID-19 pandemic is causing a significant strain on healthcare resources, leading to prioritization of coronavirus infected patients and increased risk for cardiovascular patients. Effective management of cardiac patients in hospitals during the pandemic is a challenge. This passage reviews literature and emerging guidelines on the cardiovascular implications of COVID-19, which will impact patient care, healthcare professionals, and cardiac centers.

A 77-year-old female with multiple comorbidities and a recent history of hospitalization for cerebral infarction, respiratory tract infection, and chronic cardiac failure developed acute necrotizing encephalitis (ANE), a rare complication of viral respiratory infections. At autopsy, the brain was edematous with encephalomalacia and petechial hemorrhages. Histologically

A nationwide survey of UK consultant cardiac surgeons was conducted to gather opinions on clinical decision making for patients requiring cardiac surgery during the COVID-19 pandemic. The survey received responses from 86 consultants representing all UK cardiac units. Strong consensus was achieved on performing nasopharyngeal swabs, polymerase chain reaction, and computed tomography of the chest before hospital admission, using full personal protective equipment, considering moderate to high risk of COVID-19 exposure

A survey was conducted among UK consultant cardiac surgeons to gather their opinions on clinical decision making for patients requiring cardiac surgery during the COVID-19 pandemic. A total of 86 surgeons participated, representing all UK cardiac units. Strong consensus was achieved on several key questions, including the need for pre-admission testing, full PPE use, considering moderate to high risk of COVID-19 exposure, and multidisciplinary team discussions for decision making. There was

A patient with unstable angina and multivessel coronary artery disease underwent cardiac surgery but later developed respiratory complications and died from COVID-19. This case highlights the concern for potential adverse outcomes in patients undergoing cardiac surgery with COVID-19 infection. Further investigations are required.

A study conducted at Renmin Hospital of Wuhan University in Wuhan, China, from January 20, 2020, to February 15, 2020, examined the association between cardiac injury and mortality in patients with COVID-19. Of the 416 hospitalized patients with confirmed COVID-19, 82 (19.7%) had cardiac injury. Patients with cardiac injury were older, had more

A study conducted at Renmin Hospital of Wuhan University in Wuhan, China, from January 20 to February 15, 2020, examined the association between cardiac injury and mortality in patients with COVID-19. Of the 416 hospitalized patients with confirmed COVID-19, 82 (19.7%) had cardiac injury. Patients with cardiac injury were older, had more comorbidities, and presented

A case series of five COVID-19 patients at a single institution received hyperbaric oxygen therapy (HBOT) to prevent mechanical ventilation due to tachypnoea and low oxygen saturation despite high FiO2. All patients recovered without the need for mechanical ventilation, and oxygen saturation increased, tachypnoea resolved, and inflammatory markers fell. Three patients have been discharged, and two remain stable. This small study suggests potential benefits

A case series of five COVID-19 patients at a single institution received hyperbaric oxygen therapy (HBOT) to prevent mechanical ventilation due to tachypnoea and low oxygen saturation despite high FiO2. All patients recovered without the need for mechanical ventilation, and oxygen saturation increased, tachypnoea resolved, and inflammatory markers fell. Three patients have been discharged, and two remain stable. The small sample suggests potential benefits

A study identified androgen signaling as a key modulator of angiotensin converting enzyme 2 (ACE2) levels, which is the receptor for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Treatment with 5 alpha reductase inhibitors, such as dutasteride, reduced ACE2 levels and viral entry in human cells. Clinical data showed that abnormal androgen states are linked

Two middle-aged men with no prior medical history developed new-onset atrial fibrillation during hospitalization for COVID-19 caused by SARS-CoV-2. Both patients recovered and were discharged after reverting to sinus rhythm. Physicians should be aware of the potential cardiac complications of COVID-19 and take appropriate precautions. Further research is needed to understand the viral mechanisms causing cardiac rhythm dysregulation.

The passage discusses the importance of recognizing acute cardiac injury in patients with coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). Although primarily known for causing respiratory issues, cardiac complications have been identified and may be an independent predictor for adverse outcomes. The SARS-CoV-2 virus likely uses angiotensin

A review of studies on COVID-19 and acute myocardial injury: In December 2019, SARS-CoV-2 outbreak caused COVID-19 pandemic, predominantly affecting lungs but linked to increased cardiovascular complications. Acute cardiac injury, marked by elevated cardiac troponin levels, is most common cardiac abnormality in COVID-19 and associated with mortality. This article summarizes current data on S

The Cardiac Society of Australia and New Zealand (CSANZ) released a position statement on the importance of recognizing heart involvement in critically ill COVID-19 patients. Up to one-third of these patients may develop acute cardiomyopathy, which could be myocarditis or stress cardiomyopathy. In younger patients, acute heart failure might be the cause of death, even after the acute respiratory phase. The statement proposes a screening

A nationwide survey of UK senior cardiac surgeons was conducted to gather opinions on clinical decision making for patients requiring cardiac surgery during the COVID-19 pandemic. The survey received responses from 86 consultants representing all UK cardiac units. Strong consensus was achieved on several key questions, including pre-admission testing with nasopharyngeal swab, PCR, and chest CT, full PPE use for theatre teams, and the moderate to high risk of COVID-

The COVID-19 pandemic has led to a significant reduction in hospital admissions for acute coronary syndrome (ACS) and ST-segment elevation myocardial infarction (STEMI) due to various reasons. Some factors include changed referral thresholds, healthier lifestyles, better compliance, and reduced stress. However, a more concerning reason is that patients may be staying away from hospitals due to fear of contracting the virus or limited transport options.

Community-acquired pneumonia (CAP), a global health issue, is linked to a substantial number of cardiovascular events, primarily arrhythmias, heart failure, and myocardial infarction. These events occur in all-cause CAP and CAP caused by influenza, and more recently, in COVID-19 infections. Research focuses on understanding the mechanisms of these cardiac events in pneumococcal CAP and COVID-19,

This study analyzed the clinical characteristics of 105 elderly patients with COVID-19 in Hunan Province, China. The majority were young-old patients (81.0%), and most were females (54.3%). Over two-thirds had underlying diseases, with hypertension, diabetes, and cardiac disease being the most common comorbidities. Nearly a quarter were severe or critical cases, and common symptoms included fever, cough, and fatigue

This study analyzed the clinical characteristics of 105 elderly patients with COVID-19 in Hunan Province, China. The majority were young-old patients (81.0%), and most were females (54.3%). Over two-thirds had underlying diseases, with hypertension, diabetes, and cardiac disease being the most common comorbidities. Severe and critical severe cases accounted for 22.9% and 10.5

The COVID-19 pandemic is putting significant strain on healthcare systems worldwide, with growing evidence of cardiovascular effects and increased severity for those with preexisting heart disease. As case numbers rise, there will be a greater need for post-discharge cardiac care due to an anticipated surge in new or comorbid cardiovascular patients. This report discusses the current state of post-discharge cardiac care in Canada and offers recommendations for policymakers and healthcare organizations to

The COVID-19 pandemic is putting significant strain on healthcare systems worldwide, with increasing recognition of the common and harmful cardiovascular effects of the virus. Patients with pre-existing heart conditions are at higher risk for severe disease. As case numbers rise, there will be a greater need for post-hospitalization cardiac rehabilitation. This manuscript discusses the current state of post-discharge cardiac care in Canada and offers recommendations for policymakers and healthcare organizations to prepare for

SARS-CoV-2 infection, the cause of COVID-19, is a pandemic disease primarily known for respiratory problems. However, acute cardiac injury associated with the virus cannot be disregarded as it may predict adverse outcomes. Recent findings suggest that SARS-CoV-2 uses ACE2 receptors for entry into cells, and ACE2-related signaling pathways may contribute to myocardial injury. Therefore, healthcare

This study reports on two COVID-19 patients with fulminant myocarditis who underwent ECMO treatment in Shenzhen Third People's Hospital between January 2020 and February 2020. The study compares laboratory test results and cardiopulmonary function before and after ECMO treatment at various time intervals. Both patients showed improvements in acute lung injury score, oxygenation index, albumin level, hypersensitive C-re

COVID-19, a pandemic respiratory virus, causes various cardiac complications from heart failure to diastolic dysfunction. Downregulation of angiotensin-converting enzyme-2 by COVID-19 harms the endothelium and cardiomyocytes. Hypercytokinaemia, induced by COVID-19, injures the myocardium and endothelium through interleukin-1 and inter


Question: what kinds of complications related to COVID-19 are associated with hypertension?

The World Health Organization declared COVID-19 a pandemic in March 2020. Comorbidities, including hypertension, increase the susceptibility and risk of unfavorable outcomes in COVID-19 patients. Several studies have explored the relationship between COVID-19 and hypertension, discussing potential risks such as antihypertensive therapy and management approaches.

This passage discusses the potential relationship between hypertension and the severity of coronavirus disease 2019 (COVID-19). The review questions if hypertension influences immunity or ACE2 expression, if the risks of complications are mediated by its treatment, and if aging is a major factor in patients with both hypertension and COVID-19. Recent findings suggest no evidence that hypertension or its treatment with RAS inhibitors negatively impact

The passage discusses the association between hypertension and poor prognosis in COVID-19 patients. While hypertension is a common risk factor, there is no evidence that it influences immunity or ACE2 expression in favor of viral infections. The use of RAS inhibitors, which may increase ACE2 levels, is a concern, but there is no proof that they worsen outcomes in COVID-19. Future studies are required to confirm hypertension

The COVID-19 pandemic caused by SARS-CoV-2 has resulted in thousands of deaths and no effective treatments have been identified. Many patients with COVID-19 have comorbidities such as hypertension, diabetes, and cardiovascular diseases, which are associated with a chronic inflammatory state. Severe COVID-19 patients exhibit elevated levels of inflammatory markers, which are predictive of a poor prognosis. The authors

A study identified risk factors for COVID-19 lethality in Mexico, including early-onset diabetes, obesity, COPD, advanced age, hypertension, immunosuppression, and CKD. Obesity was found to mediate 49.5% of the effect of diabetes on COVID-19 lethality. The study also developed a clinical score to predict COVID-19 lethality, including age ≥65 years

A study identified risk factors for COVID-19 lethality in Mexico, including obesity, diabetes, chronic obstructive pulmonary disease, advanced age, hypertension, immunosuppression, and chronic kidney disease. Obesity was found to mediate 49.5% of the effect of diabetes on COVID-19 lethality. The study developed a clinical score to predict COVID-19 lethality based on age, diabetes,

A study using electronic health records from Michigan Medicine identified racial differences in COVID-19 outcomes and comorbidities. Blacks/African Americans had higher hospitalization and death rates. The study, a phenome-wide association study (PheWAS), examined 1,043 pre-existing conditions and their association with COVID-19 outcomes in 5,698 patients, stratified by race. Obesity, iron deficiency anemia,

The COVID-19 pandemic poses significant challenges for managing patients with immune-mediated kidney diseases due to their compromised antiviral immunity. Hypertension, cardiovascular disease, diabetes, and older age increase the risk of severe morbidity and mortality from COVID-19. The Immunonephrology Working Group of the European Renal Association–European Dialysis and Transplant Association aims to provide recommendations for managing these patients based on available evidence

The COVID-19 pandemic poses significant challenges for managing patients with immune-mediated kidney diseases due to their compromised antiviral immunity. Hypertension, cardiovascular disease, diabetes, and older age increase the risk of severe morbidity and mortality from COVID-19. The Immunonephrology Working Group of the European Renal Association-European Dialysis and Transplant Association provides recommendations to minimize the risk of COVID-19 infection

The Mexican Society of Cardiology (SMC) and National Association of Cardiologists of Mexico (ANCAM), along with other related medical associations, have issued recommendations for patients with cardiovascular diseases during the COVID-19 pandemic. The recommendations cover general measures such as personal care, healthy eating, and regular physical activity, as well as specific topics like systemic arterial hypertension, heart failure, arrhythmias, and acute coronary syndromes. Precise

A case is presented of a patient who developed unusually rapid pulmonary hypertension and right ventricular failure after severe COVID-19 pneumonia and cytokine release syndrome. These complications, which may be caused by progressive pulmonary parenchymal and microvascular damage, have not been described before in relation to COVID-19. COVID-19 is associated with systemic and multi-organ involvement, including vascular, thrombo

The Mexican Society of Cardiology (SMC) and National Association of Cardiologists of Mexico (ANCAM), along with other Mexican medical associations, have issued recommendations on managing cardiovascular diseases during the COVID-19 pandemic. The document provides scientific analysis and responsible recommendations for patients, including personal care, healthy eating, regular physical activity, and actions in case of cardio-respiratory arrest. Precise indications are given for non-invasive cardiovascular imaging

The Mexican Society of Cardiology (SMC) and National Association of Cardiologists of Mexico (ANCAM), along with related medical associations, have issued recommendations for patients with cardiovascular diseases during the COVID-19 pandemic. The document provides general measures such as personal care, healthy eating, and regular physical activity. It also offers precise indications for non-invasive cardiovascular imaging, medication prescription, and care for specific conditions like hypertension, heart failure,

The passage discusses the need for urinary biomarkers to detect chronic kidney disease (CKD) induced by high salt intake, particularly in normotensive individuals where symptoms are not apparent. Traditional renal biomarkers like serum creatinine are insensitive for detecting kidney injury caused by high salt intake. New biomarkers for renal tubular epithelial damage such as neutrophil gelatinase-associated lip

The passage discusses the prevalence of hypertension as a comorbidity among COVID-19 patients and explores the potential association between hypertension and susceptibility to the virus, as well as the impact of hypertension on COVID-19 outcomes. While hypertension is consistently found to be the most prevalent comorbidity among COVID-19 patients, there is conflicting evidence regarding its independent predictive value on mortality. Some studies suggest that hy

The passage discusses the background and aims of a study evaluating the outcome of hypertensive patients with COVID-19 and the relation to the use of renin-angiotensin system blockers (RASB). The study found that hypertension was present in approximately 21% of COVID-19 patients, followed by diabetes in nearly 11% and established cardiovascular disease in approximately 7%. While there is an emerging suggestion of increased mortality in

The passage discusses the background and aims of a study evaluating the outcome of hypertensive patients with COVID-19 and the relation to the use of renin-angiotensin system blockers (RASB). From ten Chinese studies with a total of 2209 patients, hypertension was present in approximately 21%, followed by diabetes in nearly 11%, and established cardiovascular disease in approximately 7%. The data suggests an increased mortality

The passage discusses the disproportionate impact of hypertension on African Americans, who have a higher burden of associated comorbidities like diabetes and heart failure. The causes of hypertension in this population are primarily environmental and lifestyle factors, including poor diet, adverse lifestyle, and social determinants. Lifestyle modifications and pharmacological interventions can be used to manage hypertension, with research ongoing into the effectiveness of renal denervation, sodium-gl

The passage discusses the relationship between metabolic comorbidities, such as diabetes, obesity, and arterial hypertension, and the worsened prognosis of COVID-19. Obese individuals are more susceptible to infections and serve as a pathogen reservoir. Diabetic individuals have higher inflammatory processes due to constant glucose recognition. Hypertensive individuals, treated with ACE-inhibitors and ARBs

The passage discusses the relationship between hypertension, the renin-angiotensin system (RAS), and the risk of lower respiratory tract infections and lung injury in the context of COVID-19. Contrary to popular belief, there is no strong evidence that hypertension itself is an independent risk factor for COVID-19. However, ACE inhibitors and ARBs, which are used to treat hypertension and block the RAS,

The passage discusses the prevalence of arterial hypertension and cardiovascular diseases (CVD) among COVID-19 patients and the conflicting data regarding the effect of these comorbidities on the outcome of COVID-19. The evaluation of the treatment of hypertension and CVD in COVID-19 patients is scarce, and some investigations suggest a possible association between the renin-angiotensin-aldosterone system (RAAS)

This study examined the relationship between hypertension and COVID-19, as well as the impact of prior use of renin-angiotensin-aldosterone system (RAAS) inhibitors on the prognosis of COVID-19 patients. The study included 996 COVID-19 patients, 282 of whom had hypertension. Patients with hypertension had more severe secondary infections, cardiac and renal dysfunction, and

The passage discusses the relationship between hypertension, the renin-angiotensin system (RAS), and the risk of lower respiratory tract infections and lung injury in the context of COVID-19. Contrary to popular belief, there is a lack of solid evidence that hypertension itself is an independent risk factor for COVID-19. Instead, ACE inhibitors and ARBs, which are used to treat hypertension and block the R

The passage discusses the role of microRNAs (miRNAs) in endothelial dysfunction and hypertension, which is a major risk factor for cardiovascular disease. The review summarizes the current understanding of the mechanisms underlying hypertension and its association with endothelial dysfunction, and the role of miRNAs in endothelial cells. The latest findings include the modulation of the renin-angiotensin-aldoster

A study aimed to map COVID-19-related worries and overall psychosocial health among people with diabetes in Denmark during the initial pandemic phase. The survey of 2430 adult diabetic panel members revealed that over half were worried about being disproportionately affected by COVID-19 due to their diabetes, and one-third were concerned about being labeled as high-risk and struggling to manage diabetes if infected. Logistic regression analysis identified females, those with type

A study aimed to map COVID-19-related worries and overall psychosocial health among people with diabetes in Denmark. The survey of 2430 adults with diabetes revealed that over half were worried about being disproportionately affected by COVID-19 due to their diabetes, and one-third were concerned about being labeled as high-risk and struggling to manage diabetes if infected. Logistic regression analysis identified females, those with type 1 diabetes, diabetes complications

A study found a positive correlation between the number of confirmed COVID-19 cases and the GDP at the prefectural level in Chinese Mainland as of February 2020. Cities with higher GDP had more confirmed cases during the epidemic spread.

A retrospective study of hypertensive patients with Covid-19 found that older age, diabetes, and hypertensive myocardiopathy increased the risk of severe Covid-19 hospitalization. Contrary to previous hypotheses, ARB treatment was associated with a lower risk of hospitalization (HR: 0.29, 95% CI: 0.10 - 0.88), while the trend was similar but not significant

A retrospective study of hypertensive patients with Covid-19 found that older age, diabetes, and hypertensive myocardiopathy increased the risk of severe Covid-19 hospitalization. Contrary to previous hypotheses, ARB treatment was associated with a lower risk of hospitalization (HR: 0.29, 95% CI: 0.10 – 0.88), while the trend was similar but not significant

The study investigated the relationship between hypertension, use of renin-angiotensin system (RAS) inhibiting medications, and the expression of Angiotensin Converting Enzyme 2 (ACE2) in the kidney. Contrary to previous hypotheses, the data from 436 patients revealed no association between hypertension or common RAS inhibiting drugs and renal expression of ACE2. The study also found that ACE2

This retrospective cohort study analyzed the medical records of 1031 COVID-19 patients admitted to Tongji Hospital in Wuhan, China between January 27 and March 8, 2020. Of the 165 patients who died in hospital, 73% had chronic comorbidities, with hypertension being the most common. Patients with hypertension had a 2.8-fold increased risk of mort

A systematic review and meta-analysis of 30 studies found that Diabetes Mellitus (DM) is associated with a higher risk of composite poor outcomes, including mortality, severe COVID-19, acute respiratory distress syndrome (ARDS), and disease progression, in patients with COVID-19 pneumonia. The association was stronger in older patients and those with hypertension. The meta-analysis showed that DM increased the risk of composite poor outcomes

A systematic review and meta-analysis of 30 studies found that Diabetes Mellitus (DM) is associated with a higher risk of composite poor outcomes, including mortality, severe COVID-19, acute respiratory distress syndrome (ARDS), and disease progression, in patients with COVID-19 pneumonia. The association was stronger in younger patients and those without hypertension. Meta-regression indicated that age and hypertension influenced the association

The passage presents findings from a study using the Panel Study of Income Dynamics (PSID) to estimate the risk of severe complications from COVID-19 in the US, revealing significant disparities based on race-ethnicity and socioeconomic status. The study highlights the prevalence of health conditions like hypertension linked to COVID-19 complications and shows these disparities emerge early in life, increasing vulnerability to severe respiratory infections for non-His

The passage discusses how older adults and those with comorbidities, such as hypertension, cardiovascular disease, diabetes, chronic respiratory disease, and chronic kidney disease, are at higher risk for severe outcomes and mortality from COVID-19 caused by the novel SARS-CoV-2 virus. Older adults in the US have a significant percentage of these conditions, increasing their risk of infection. Medications like angiotensin-converting

The COVID-19 pandemic is caused by the novel virus SARS-CoV-2, which leads to worse outcomes and higher mortality rates in older adults and those with comorbidities like hypertension, cardiovascular disease, diabetes, chronic respiratory disease, and chronic kidney disease. Many older adults have these conditions and are also taking medications such as ACE inhibitors and angiotensin II receptor blockers, which may upregulate the A

This retrospective observational study examined the relationship between hypertension, antihypertensive treatment, and mortality in patients diagnosed with COVID-19 at Huo Shen Shan Hospital in Wuhan, China. Among 2877 patients, 29.5% had a history of hypertension. After adjusting for confounders, patients with hypertension had a two-fold increase in mortality risk compared to those without hypertension (4

During the COVID-19 lockdown in India, a study of 150 patients with type 2 diabetes found that 21% reported an increase in carbohydrate consumption, 23% snacked more frequently, 27% consumed more fruits, 42% exercised less, 19% gained weight, and 23% did self-monitoring of blood glucose less often. Additionally, 87% reported mental stress

A study of 133 hypertensive COVID-19 patients found no significant difference in hospital admission rates, oxygen therapy, or need for non-invasive ventilation between those taking angiotensin-converting enzyme inhibitors (ACEIs) or angiotensin II receptor blockers (ARBs). However, those on RAAS inhibitors had a lower rate of admission to semi-intensive/intensive care units (OR 0

This passage reports on a single-center experience of treating 501 intracranial aneurysms with stent-assisted coiling over an 8-year period. The study identified 22 (4.58%) procedure-related complications, resulting in death for 4 patients (0.83%) and morbidity for 4 patients (0.83%). Complications were more common in patients with hypertension, those who under

A systemic review and meta-analysis of clinical data on COVID-19 patients identified preexisting chronic conditions like hypertension, cardiovascular disease, chronic kidney disease, and diabetes as risk factors for severe disease and increased mortality. Acute cardiac injury and acute kidney injury were also found to be strongly correlated with COVID-19-related mortality. Close monitoring of organ function is recommended for COVID-19 patients due to the high risk of

Hypertension is a prevalent issue among adults in Haiti, leading to a high rate of morbidity and cardiovascular disease-related hospital admissions. An integrative review of eight publications identified common themes of high prevalence in rural areas, public health challenges, lack of awareness, and barriers to effective treatment. Further research and culturally tailored prevention strategies and disease management programs are recommended to better serve this vulnerable population. There is a need for more quality evidence to guide

During the COVID-19 outbreak, pregnant women should be classified as low or high risk for hypertensive disorders and adjustments made to antenatal care accordingly. All pregnant women should have a sphygmomanometer at home and monitor for signs of hypertension. Women with suspected hypertensive disorders and severe symptoms should be evaluated with blood tests and possibly hospitalized. Current guidelines suggest delivery after 34 weeks with preeclampsia, but during COVID-19,

During the COVID-19 pandemic, pregnant women should be classified as low or high risk for hypertensive disorders of pregnancy to minimize unnecessary visits to healthcare facilities. All pregnant women should have a sphygmomanometer at home and be instructed on signs and symptoms of hypertension. Women with suspected hypertensive disorders and severe symptoms should undergo evaluation including blood tests and possible hospitalization. Current guidelines suggest delivery after 34 weeks with preeclampsia, but during

The passage discusses the significance and increasing prevalence of hypertension (HTN), the leading risk factor for adverse cardiovascular disease outcomes. Several organizations have recently updated their guidelines for HTN diagnosis and treatment. This review compares the latest guidelines from the American College of Cardiology/American Heart Association, multiple U.S. societies, European Society of Cardiology/European Society of Hypertension, National Institute for Care and Health Excellence, and International Society of

The passage discusses the potential relationship between cholesterol levels and the severity of COVID-19. Patients with cardiovascular disease, hypertension, and obesity may experience more severe cases of COVID-19. High cholesterol levels are linked to an increased number of ACE2 receptors, which SARS-CoV-2 uses for entry into host cells. Statins, which lower cholesterol levels, have been suggested

This review summarizes current knowledge on COVID-19 and pregnancy. The virus, which has been a global health issue since December 2019, has been linked to adverse pregnancy outcomes. The review aims to provide an overview of symptoms in pregnant women with COVID-19 and potential risks to fetuses and neonates. Data was extracted from studies published in English on Web of Science, Cochrane, PubMed, and Scopus up to April 2,

The passage is a review summarizing current knowledge about COVID-19 and its impact on pregnancy. The review covers early symptoms of COVID-19, which include fever, cough, dyspnea, myalgia, and fatigue, and less common symptoms such as sputum production, headache, hemoptysis, and diarrhea. There is no evidence of vertical maternal-fetal transmission of COVID-19. Pregnant women with COVID-1

A meta-analysis of 26 studies found that the incidence of acute kidney injury (AKI) in patients with COVID-19 was 8.4% (95% CI 6.0% to 11.7%), with a pooled incidence of renal replacement therapy of 3.6% (95% CI 1.8% to 7.1%). The incidence of AKI was higher

The passage suggests a potential link between oral health and the severity of COVID-19 complications. Patients with severe COVID-19 often have underlying conditions like obesity, diabetes, and hypertension. Periodontitis, a common oral disease, is linked to non-oral systemic diseases. The oral cavity can harbor respiratory pathogens, increasing the risk of hospital-acquired pneumonia in patients with periodontal disease. Therefore,

COVID-19, a global pandemic causing strain on healthcare and economies, impacts the cardiovascular system in addition to the lungs. Patients with underlying cardiovascular diseases and risk factors face increased severity and mortality from COVID-19. Conversely, COVID-19 leads to various cardiovascular complications, enhancing morbidity and mortality. It's essential to stay updated on the evolving data regarding the cardiovascular involvement of COVID-1

During the COVID-19 pandemic, routine health services have been reduced, and specialists have shifted to focus on COVID-19 cases. Obstetric assistance cannot be suspended, but safety measures are necessary. Changes in clinical habits are required to accommodate COVID-19 positive pregnant patients, who need additional care. This report details the management setup in an Obstetrics and Gynecology Unit at a University Hospital in Milan, Italy, during the COVID-19 era.

During the COVID-19 pandemic, obstetric assistance couldn't be suspended despite the need to reorganize the entire healthcare system. In Milan, Italy, a University Obstetrics and Gynecology Department adapted to ensure safety for pregnant patients, who require additional care if positive for COVID-19. Clinical habits were changed to address emerging needs.

A systematic review was conducted to examine the relationship between hypertension, diabetes, stroke, cancer, kidney disease, and high-cholesterol with COVID-19 disease severity and fatality. A search of 59,000 articles was conducted using an automated search engine, resulting in 54 articles for full review. Diabetes, hypertension, and high cholesterol were found to have an apparent relation to COVID-19 severity

A meta-analysis of nine studies involving 3936 patients with hypertension and COVID-19 infection found that ACEI/ARB therapy, part of RAAS inhibitors, was not associated with disease severity but was linked to lower mortality rates (OR 0.57, 95% CI 0.38-0.84, P 0.004, I2 0). The use of RAAS

A systematic review was conducted to examine the relationship between hypertension, diabetes, stroke, cancer, kidney issues, and high-cholesterol with COVID-19 disease severity. A search of 59,000 articles was reduced to 54 after filtering using keywords and questions. Diabetes, hypertension, and high cholesterol were found to have a relation to COVID-19 severity, but further research is needed for cancer

The study aimed to describe the clinical characteristics of COVID-19 related deaths in adults (< 65 years) and older adults (≥ 65 years) in Italy. The analysis of medical charts of 3,032 patients revealed that older adults had more comorbidities and higher prevalence of certain conditions like ischemic heart disease, atrial fibrillation, heart failure, stroke, hypertension, dementia, COPD, and chronic re

The COVID-19 pandemic, which had claimed over 137,000 lives as of April 2020, has prompted the global scientific community to focus on containing and stopping its spread. This requires collaboration among researchers and practitioners in various fields, raising questions about research priorities, coordination, and involvement. In a comparative bibliometric study of six infectious disease outbreaks since 2000, including COVID-19, the present paper finds

The passage discusses the potential relationship between high blood pressure, comorbidities, and the susceptibility to and mortality from COVID-19. It mentions the hypothesis that excessive activation of the renin-angiotensin system (RAS) could contribute to COVID-19 related lung injury, leading to concerns about the use of angiotensin II receptor blockers (ARBs) and angiotensin converting enzyme (ACE) inhibitors due

A retrospective study of 113 hypertensive Covid-19 patients found that those using angiotensin-converting enzyme inhibitors (ACE inh) and angiotensinogen receptor blockers (ARBs) had a higher in-hospital mortality rate (30.9%) than those not using these medications (OR: 3.66; 95%CI: 1.11-18.

The study assessed the relationship between previous use of ACE inhibitors, angiotensin-receptor blockers, beta-blockers, calcium-channel blockers, or thiazide diuretics and the likelihood of testing positive for Covid-19 or developing severe illness among patients with positive results. Using Bayesian methods, the study found no substantial increase in the likelihood of a positive test or in the risk of severe illness associated with any of these medication classes.

The study aimed to describe the clinical characteristics of COVID-19 related deaths in adults under 65 years and older adults over 65 years in Italy. The analysis of medical charts of 3,032 patients revealed that older adults had more comorbidities and higher prevalence of certain conditions like ischemic heart disease, atrial fibrillation, heart failure, stroke, hypertension, dementia, COPD, and chronic renal failure. In

A study aimed to develop a model to estimate the risk status of patients at a nationwide pharmacy chain in the US for severe COVID-19 complications. The model used age, underlying health conditions, and urban density as risk parameters. Of the 30 million adults included, nearly 63% were considered high-risk, with age being the biggest contributor. The study showed that certain counties have high-risk populations and the interactive map can aid in proactive planning

A study aimed to develop a model to estimate the risk status of patients at a nationwide pharmacy chain in the US for severe COVID-19 complications, using age, underlying health conditions, and urban density as risk parameters. Of the 30 million adults included, nearly 63% were considered high-risk, with age being the biggest contributor. The model, using data from about 10% of the US population, is the most comprehensive to estimate county-level

A patient with idiopathic pulmonary fibrosis (IPF) contracted COVID-19 from their spouse and died from complications. IPF, a disease more prevalent in the elderly, increases the risk of serious complications from COVID-19. Few reviews exist on COVID-19 in IPF patients, making this case noteworthy for raising awareness and emphasizing the importance of precautions for IPF patients to reduce the risk of contract

The study aimed to analyze risk factors for death in patients with severe and critical COVID-19 and construct a predictive model using logistic regression. The analysis of 105 patients revealed that older age, male gender, comorbidities (coronary heart disease, hypertension, myocardial damage, thrombocytopenia), and mechanical ventilation were significant risk factors for mortality. The constructed model had an AUC of 0.8

The study aimed to analyze risk factors of death and their predictive value in patients with severe and critical COVID-19 using logistic regression at Yangtze River Shipping General Hospital in Wuhan. Of the 105 patients, 42 died and 63 survived. Older age, male gender, comorbidities (coronary heart disease, hypertension, myocardial damage, thrombocytopenia), and mechanical ventilation

The study aimed to analyze the expression of SARS-CoV-2 receptors and related molecules in various primary human cells and tissues from healthy individuals and those with risk factors and comorbidities of COVID-19. RNA sequencing and available databases were used to explore gene expression and co-expression of ACE2, CD147 (BSG), CD26 (DPP4), and their molecular partners in bronchial epithel

The passage discusses a study aiming to analyze the expression of potential SARS-CoV-2 receptors and related molecules in various primary human cells and tissues from healthy individuals and those with risk factors and comorbidities of COVID-19. The study used RNA sequencing and available databases to explore gene expression and co-expression of ACE2, CD147 (BSG), CD26 (DPP4), and their molecular partners

The COVID-19 pandemic has disproportionately affected individuals with obesity, who are at higher risk for severe complications and mortality. This is due to the presence of obesity-related comorbidities, such as pulmonary diseases, and immune system impairments that worsen the infection. Prevention through social distancing, hygiene, and a healthy lifestyle is crucial. Obesity patients should prioritize access to primary care services and

The COVID-19 pandemic has infected over ten million people with over 500,000 deaths, and about half have recovered. A subgroup of individuals, particularly those with obesity, are at greater risk of severe complications and higher mortality. Obesity-related comorbidities, such as pulmonary diseases, and immune system impairments increase vulnerability to COVID-19. Prevention includes social distancing, hygiene, and

The Swedish Registry for Renal Denervation study analyzed data from 252 patients with resistant hypertension who underwent renal denervation between 2011 and 2015. The results showed a significant decrease in office and ambulatory blood pressure six months after the procedure, which persisted for up to 36 months. Major vascular complications occurred in four patients, and there were no changes in renal function or the number of ant

This multicenter study reports on the impact of the COVID-19 pandemic on orthopedic and trauma services in three hospitals in Tuscany, Italy. During the COVID-19 era in March 2020, scheduled surgeries drastically decreased, with most procedures being carried out for tumors, infections, and implant mobilizations. Trauma activities slightly decreased, with proximal femur fractures remaining constant and minor traumas drastically

A scoping review summarized 24 reported cases of Guillain-Barre Syndrome (GBS) associated with COVID-19. Most cases were from Italy and the USA, affecting mostly males aged 23-84 years. Clinical presentations included typical sensory-motor GBS, facial palsy, abducent nerve palsy, and paraparetic GBS variant with autonomic dysfunction. Electrodiagnostics confirmed ac

This passage aims to update mental health professionals on the changing definition of COVID-19 diagnosis, focusing on available tests for diagnosis and antibody detection. It also provides information about the disease, risks, and ongoing treatment developments. The article concludes with resources for further information.

A study was conducted to examine the precautions taken by Turkish dentists in dental clinics during the COVID-19 pandemic. The survey was sent to 1,958 Turkish dentists between March 16 and March 20, 2020. Of the respondents, 65.1% were general dentists and 34.9% were specialists. Only 26.7% of dentists had attended an informational meeting on

A study was conducted to examine the precautions taken by Turkish dentists in dental clinics during the COVID-19 pandemic. The survey included 1,958 Turkish dentists, with 65.1% being general dentists and 34.9% specialists. Most dentists were aware of COVID-19 and concerned about themselves and their families, but only 12% wore N95 masks. While some precautions were taken, they were

The passage is a summary of a meta-analysis study on the prevalence and risk factors of COVID-19. The study found that fever, cough, fatigue, and dyspnea were the most common symptoms in COVID-19 patients, with incidences of 85.6%, 65.7%, 42.4%, and 21.4%, respectively. The most prevalent comorbidities were hypertension (15.6

The passage is a summary of a meta-analysis study on COVID-19. The study found that fever, cough, fatigue, and dyspnea are the most common symptoms in COVID-19 patients, with prevalence rates of 85.6%, 65.7%, 42.4%, and 21.4%, respectively. Comorbidities such as diabetes, hypertension, cardiovascular disease, and malignancy were present in

This passage is about a study that aimed to evaluate the association between hypertension and the severity or mortality of COVID-19. The study identified and pooled data from various sources to calculate the odds ratio of hypertension in patients with severe COVID-19 and those who died from the disease. The results showed that hypertension was significantly associated with a 2.5-fold increased risk of severe COVID-19 and a similar increase in mortality risk. Additionally

The study identified 49.1% of COVID-19 patients admitted to Tongji Hospital in Wuhan between January 26, 2020 and February 5, 2020 as severe cases. Elder age, hypertension, high cytokine levels (IL-2R, IL-6, IL-10, and TNF-a), and high LDH level were risk factors for severe COVID-19.

The study identified 49.1% of COVID-19 patients admitted to Tongji Hospital in Wuhan as severe cases. Factors associated with severe COVID-19 on admission included older age, hypertension, high cytokine levels, and high lactate dehydrogenase. The mortality rate was 32.5% in severe cases compared to 1.1% in nonsevere cases during the follow-up period. F

A study was conducted to assess the outcomes of laparoscopic sleeve gastrectomy (LSG) as a treatment for morbid obesity. The review included 183 patients between 2009 and 2015. At one year post-op, median percentage excess body weight loss (%EWL) was 57.6% with a reduction in BMI of 16 kg/m2. At two years, median %

The COVID-19 outbreak caused by the SARS-CoV-2 virus poses a significant threat to global health and causes social and economic disruption. The virus enters and infects cells through Angiotensin-converting enzyme 2 (ACE2), which is expressed in endothelial cells, respiratory epithelium, and other cell types. In normal conditions, ACE2 generates angiotensin fragments and plays a crucial

A retrospective study of 110 COVID-19 patients at Wuhan Fourth Hospital found that hypertensive patients had a lower lymphocyte count and higher crude mortality rate compared to non-hypertensive patients. Patients with hypertension who took ACEI or ARB drugs were younger but had similar crude cure and mortality rates. The study suggests that hypertension and old age may increase the risk of poor outcomes in COVID-1

A female academic reflects on the intersection of motherhood and academic productivity during Covid-19. A hospital procedure brought up feelings of mothering and being mothered, highlighting how these roles impact relationships. The author aims to provide support and contain fear and anxiety for all women during this challenging time.

The passage suggests that early data from COVID-19 patients in Wuhan revealed that a significant number of them were male, aged 40 to 60, and had comorbidities such as cardiovascular disease and hypertension. Among hospitalized ICU patients, 25% had cardiovascular disease and 58% had hypertension, compared to 10% and 22% for non-ICU patients. The authors suggest that individuals

The Republic of Panama, with its high wealth inequality and high COVID-19 incidence rate, offers valuable insights into potential risks and research opportunities for Latin American countries. This paper explores two questions: what unique risks does Panama face that could prepare other countries, and what scientific knowledge can Panama contribute to the regional and global study of COVID-19? The paper suggests ways for the research community to support local health authorities in planning for different scenarios and reducing public anxiety. It also

The COVID-19 pandemic, declared in March 2020, affects many patients with underlying chronic conditions like diabetes, cardiovascular disease (CVD), and hypertension. The literature review discusses the lack of evidence on managing diabetes during COVID-19 infection. The presence of diabetes and CVD increases inflammation and worsens patient outcomes. Therefore, managing dysglycemia and other CVD risk factors is crucial. The review explores the possible links

Periodontal disease (PD), a group of inflammatory and dysbiotic conditions affecting periodontal tissues, is linked to various risk factors such as diabetes, obesity, aging, and hypertension. These same factors are associated with severe COVID-19 illness caused by SARS-CoV-2. The connection between PD and COVID-19 severity suggests that periodontal status could indicate the risk of complications. However, no reports exist

Periodontal disease (PD), a group of inflammatory and dysbiotic conditions affecting periodontal tissues, is linked to various risk factors such as diabetes, obesity, aging, and hypertension. These factors are also associated with severe COVID-19 illness caused by SARS-CoV-2. Given the systemic implications of PD and these comorbidities, assessing periodontal status in COVID-19 patients could help identify risk