Datasets:

mfromm
/

AMSR

{"forum": "Byg1E7KIIr", "submission_url": "https://openreview.net/forum?id=Byg1E7KIIr", "submission_content": {"TL;DR": "We present a novel approach to spike sorting using the Neural Clustering Process (NCP), a recently introduced neural architecture that performs scalable amortized approximate Bayesian inference for efficient probabilistic clustering.", "keywords": ["spike sorting", "neural clustering process", "bayesian clustering", "amortization"], "pdf": "/pdf/4b82faee592cab86045499b3c95ee6a34694559b.pdf", "authors": ["Yueqi Wang", "Ari Pakman", "Catalin Mitelut", "JinHyung Lee", "Liam Paninski"], "title": "Spike Sorting using the Neural Clustering Process", "abstract": "We present a novel approach to spike sorting for high-density multielectrode probes using the Neural Clustering Process (NCP), a recently introduced neural architecture that performs scalable amortized approximate Bayesian inference for efficient probabilistic clustering. To optimally encode spike waveforms for clustering, we extended NCP by adding a convolutional spike encoder, which is learned end-to-end with the NCP network. Trained purely on labeled synthetic spikes from a simple generative model, the NCP spike sorting model shows promising performance for clustering multi-channel spike waveforms. The model provides higher clustering quality than an alternative Bayesian algorithm, finds more spike templates with clear receptive fields on real data and recovers more ground truth neurons on hybrid test data compared to a recent spike sorting algorithm. Furthermore, NCP is able to handle the clustering uncertainty of ambiguous small spikes by GPU-parallelized posterior sampling. The source code is publicly available.", "authorids": ["yueqi.wang.pku@gmail.com", "aripakman@gmail.com", "mitelutco@gmail.com", "jl4303@columbia.edu", "liam@stat.columbia.edu"], "paperhash": "wang|spike_sorting_using_the_neural_clustering_process"}, "submission_cdate": 1568211750990, "submission_tcdate": 1568211750990, "submission_tmdate": 1572488548746, "submission_ddate": null, "review_id": ["HyxmsEuDvS", "rklA_lFtwS"], "review_url": ["https://openreview.net/forum?id=Byg1E7KIIr&noteId=HyxmsEuDvS", "https://openreview.net/forum?id=Byg1E7KIIr&noteId=rklA_lFtwS"], "review_cdate": [1569322138708, 1569456246265], "review_tcdate": [1569322138708, 1569456246265], "review_tmdate": [1570047560098, 1570047552795], "review_readers": [["everyone"], ["everyone"]], "review_writers": [["NeurIPS.cc/2019/Workshop/Neuro_AI/Paper25/AnonReviewer1"], ["NeurIPS.cc/2019/Workshop/Neuro_AI/Paper25/AnonReviewer2"]], "review_reply_count": [{"replyCount": 0}, {"replyCount": 0}], "review_replyto": ["Byg1E7KIIr", "Byg1E7KIIr"], "review_content": [{"evaluation": "3: Good", "intersection": "3: Medium", "importance_comment": "While spike sorting is probably not the major bottleneck to our effective use & interpretation of large multi-electrode array neural recordings, there is definitely room for improvement on current methods - in performance, versatility & comp. efficiency. Hence the work can be considered marginally important.\n", "clarity": "4: Well-written", "technical_rigor": "3: Convincing", "intersection_comment": "This is clearly a description of trying to optimise machine learning approaches for a well known, 'hard' problem in neuroscience. Hardly see any 'AI' relation.", "rigor_comment": "Description of the algorithm is rigorous enough for this setting, as is comparison to other models. Perhaps would be nice to see comparisons to YASS (if possible) since this seems to outperform Kilosort? Similarly since the model is by definition trained on synthetic data, the richness & 'accuracy' of this generative model is key. Hence my label 'preliminary'.", "comment": "Paper is well written and fairly easy to read. The efficiency of amortised methods seems clear for increasingly large data sets, but perhaps a point of concern is how confident we can be about doing supervised learning for an inherently 'unsupervised' problem?! Training on synthetically labelled data to do inference on true data? ", "importance": "3: Important", "title": "Clear & well written, if preliminary :-)", "category": "AI->Neuro", "clarity_comment": "The text is well written & clear, making the shortfalls of previous methods explicit & being clear about which of these the proposed method aims to address. \nPerhaps the data pre-processing section could be a little clearer. A little ambiguous is \"We partitioned the recording data such that the data for each channel only contains spikes centered at that channel\" but then to also say \"For each spike, the extracted waveform is... from the center channel and its 6 immediate neighbor channels.\" This could perhaps be better phrased?\n\n"}, {"title": "Another spike sorting algorithm based on neural network", "importance": "4: Very important", "importance_comment": "Efficient and accurate spike sorting algorithm for multi-channel extracellular recordings is necessary, especially in the low SNR (small spikes) domain. ", "rigor_comment": "Used a previously developed neural network structure to handle neural data. The network structure and logic is very clear. However, it is a bit unclear how well this algorithm perform to reduce the uncertainty of small amplitude spikes compared to other algorithms. It is also a bit unclear whether there is over-splitting of clusters in this algorithm.", "clarity_comment": "The text is well written. ", "clarity": "4: Well-written", "evaluation": "4: Very good", "intersection_comment": "Used AI technique to solve spike sorting problem. ", "intersection": "4: High", "technical_rigor": "3: Convincing", "category": "AI->Neuro"}], "comment_id": [], "comment_cdate": [], "comment_tcdate": [], "comment_tmdate": [], "comment_readers": [], "comment_writers": [], "comment_reply_content": [], "comment_content": [], "comment_replyto": [], "comment_url": [], "meta_review_cdate": null, "meta_review_tcdate": null, "meta_review_tmdate": null, "meta_review_ddate ": null, "meta_review_title": null, "meta_review_metareview": null, "meta_review_confidence": null, "meta_review_readers": null, "meta_review_writers": null, "meta_review_reply_count": null, "meta_review_url": null, "decision": "Accept (Poster)"}