Datasets:
ZhiyuanChen
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README.md
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---
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language: rna
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tags:
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- Biology
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- RNA
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license:
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- agpl-3.0
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size_categories:
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- 10K<n<100K
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source_datasets:
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- multimolecule/bprna
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- multimolecule/pdb
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task_categories:
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- text-generation
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- fill-mask
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task_ids:
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- language-modeling
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- masked-language-modeling
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pretty_name: RNAStrAlign
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library_name: multimolecule
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---
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# RNAStrAlign
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RNAStrAlign is a comprehensive dataset of RNA sequences and their secondary structures.
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RNAStrAlign aggregates data from multiple established RNA structure repositories, covering diverse RNA families such as 5S ribosomal RNA, tRNA, and group I introns.
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It is considered complementary to the [ArchiveII](./archiveii) dataset.
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## Disclaimer
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This is an UNOFFICIAL release of the RNAStrAlign by Zhen Tan, et al.
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**The team releasing RNAStrAlign did not write this dataset card for this dataset so this dataset card has been written by the MultiMolecule team.**
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## Dataset Description
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- **Homepage**: https://multimolecule.danling.org/datasets/rnastralign
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- **datasets**: https://huggingface.co/datasets/multimolecule/rnastralign
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- **Point of Contact**: [David H. Mathews](mailto:David_Mathews@urmc.rochester.edu) and [Gaurav Sharma](mailto:gaurav.sharma@rochester.edu)
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## Example Entry
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| id | sequence | secondary_structure | family | subfamily |
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| -------------------------------- | ----------------------------------- | ------------------------------------ | ---------- | -------------- |
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| 16S_rRNA-Actinobacteria-AB002635 | ACACAUGCAAGCGAACGUGAUCUCCAGCUUGC... | .(((.(((..((..((((.(((((.((....)... | 16S_rRNA | Actinobacteria |
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## Column Description
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- **id**:
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A unique identifier for each RNA entry. This ID is derived from the family and the original `.sta` file name, and serves as a reference to the specific RNA structure within the dataset.
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- **sequence**:
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The nucleotide sequence of the RNA molecule, represented using the standard RNA bases:
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- **A**: Adenine
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- **C**: Cytosine
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- **G**: Guanine
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- **U**: Uracil
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- **secondary_structure**:
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The secondary structure of the RNA represented in dot-bracket notation, using up to three types of symbols to indicate base pairing and unpaired regions, as per bpRNA's standard:
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- **Dots (`.`)**: Represent unpaired nucleotides.
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- **Parentheses (`(` and `)`)**: Represent base pairs in standard stems (page 1).
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- **family**:
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The RNA family to which the sequence belongs, such as 16S rRNA, 5S rRNA, etc.
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- **subfamily**:
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A more specific subfamily within the family, such as Actinobacteria for 16S rRNA.
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Not all families have subfamilies, in which case this field will be `None`.
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## Variations
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This dataset is available in two additional variants:
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- [rnastralign](https://huggingface.co/datasets/multimolecule/rnastralign): The main RNAStrAlign dataset.
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- [rnastralign.512](https://huggingface.co/datasets/multimolecule/rnastralign.512): RNAStrAlign dataset with sequences no longer than 512 nucleotides.
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- [rnastralign.1024](https://huggingface.co/datasets/multimolecule/rnastralign.1024): RNAStrAlign dataset with sequences no longer than 1024 nucleotides.
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## Related Datasets
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- [ArchiveII](https://huggingface.co/datasets/multimolecule/archiveii): A database of RNA secondary with the same families as RNAStrAlign, usually used for testing.
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- [bpRNA-spot](https://huggingface.co/datasets/multimolecule/bprna-spot): Another commonly used database in RNA secondary structures prediction.
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## License
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This dataset is licensed under the [AGPL-3.0 License](https://www.gnu.org/licenses/agpl-3.0.html).
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```spdx
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SPDX-License-Identifier: AGPL-3.0-or-later
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```
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## Citation
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```bibtex
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@article{ran2017turbofold,
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author = {Tan, Zhen and Fu, Yinghan and Sharma, Gaurav and Mathews, David H},
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journal = {Nucleic Acids Research},
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month = nov,
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number = 20,
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pages = {11570--11581},
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title = {{TurboFold} {II}: {RNA} structural alignment and secondary structure prediction informed by multiple homologs},
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volume = 45,
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year = 2017
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}
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```
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train.parquet
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version https://git-lfs.github.com/spec/v1
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oid sha256:5b784f4175be29ed16ead9cd7d65be3de1dae3a746f589cdcbebeffe7627f093
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size 761217
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