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9,900
Cumulative index of reviews for 1980–1985
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Proteins: stay tuned!
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9,902
Response from Lane and Buchmeier
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9,903
The aquaporin family of membrane water channels
The rapid movement of water across the plasma membranes of certain cells has been a long-standing puzzle to membrane biophysicists and physiologists; the discovery of the red cell channel-forming integral protein has provided a molecular solution to this puzzle. The identification of this protein has led to the recognition of a family of related water-selective channels, the aquaporins, that are found in animals, plants and microbial organisms. In order to provide insight into the remarkable but simple function of these membrane proteins, their structures are being elucidated.
9,904
Membrane proteins
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9,905
Deep life
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9,906
Cumulative Index 2004
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9,907
Pyelonephrite aigue chez l'entant a propos de 79 cas
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9,908
Diagnostic des infections respiratoires par amplification des acides nucléiques
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9,909
Complications de la rougeole et facteurs de risque de deces
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9,910
Current opinion in structural biology
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9,911
Forthcoming Articles
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Forthcoming articles page
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9,913
Double dealing
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9,914
Role pathogene des coronavirus humains chez l'enfant: analyse systematique de la litterature
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9,915
Subject index for research articles and reviews, 1989
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9,916
Tolerance d'infanrix polio-Hib en rappel chez 950 nourrissons
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9,917
Des vaisseux et des gènes
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9,918
Proteins — discovery and detail
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9,919
Digénisme : le retour
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9,920
RNA pseudoknots
Many new RNA pseudoknot structures have been detected and proposed in the past year. Although we are still waiting for the first detailed structure of a pseudoknot, their role in processes such as translational autoregulation or ribosomal frameshifting has been extensively studied and is now well established. Pseudoknot structures appear to play a pivotal role in small subunit ribosomal RNA and in the noncoding regions of viral RNAs. There are also strong indications that RNA pseudoknots are highly suitable structural motifs for the recognition and binding of proteins.
9,921
Contents and Editorial Board
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9,922
Editorial Board and Contents
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9,923
Patent reports
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9,924
Department of Error
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9,925
Editorial Board and Contents
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9,926
Patent reports
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9,927
Contents and Editorial Board
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9,928
Erratum
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9,929
Index to volume 29
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9,930
Sobre la necesidad de modernizar la vigilancia epidemiológica y de ampliar el uso del diagnóstico molecular para las enfermedades infecciosas en Colombia
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9,931
Author indexes
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9,932
Editorial Board and Contents
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9,933
New methodologies for the pathologic diagnosis of placental infections-immunohistochemistry, immunofluorescence, in situ nucleic acid hybridization and polymerase chain reaction: A review
A variety of highly sensitive laboratory techniques is now available for the detection and localization of infectious agents in the placenta. This communication discusses, the role of immunohistochemistry, immunofluorescence, in situ nucleic acid hybridization, and polymerase chain reaction for infectious disease diagnosis in formalinfixed placental tissues. These techniques, as well as other sophisticated molecular methods currently in development, will greatly facilitate characterizing the role of infectious agents in a variety of perinatal and pediatric conditions, including birth defects, intrauterine growth retardation, and stillbirth.
9,934
Patent reports
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9,935
Patent Reports
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9,936
Recent research in infectious disease
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Editorial Board and Contents
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9,938
Contents of other veterinary journals from Elsivier
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9,939
Recent research in infectious disease
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Gastroenteritis in Auckland: An aetiological and clinical study
Faecal specimens from 60 patients (under six years old), most of whom were Maoris and Pacific Islanders admitted to Auckland Hospital with gastroenteritis during the months of June and July 1977, were examined for the presence of faecal viruses, bacterial pathogens and parasites. Faecal specimens from 18 non-diarrhoeal control patients were also examined, of which three contained rotavirus. Forty-three (72 per cent) gastroenteritis patients had rotavirus detectable in stools by electron microscopy or immune electron microscopy. Of the remainder, 17 patients were regarded as having non-rotavirus diarrhoea. Enterotoxigenic Esch. coli. was isolated from seven patients of whom six yielded stable toxin producers (ST+), four labile toxin producers (LT+) and two dual toxigenic strains (ST+/LT+). All ST+ isolates appeared to be of low enterotoxigenicity as indicated by low gut weight/carcass weight ratios in the infant mouse assay. Rotavirus was the commonest aetiological agent (72 per cent), bacterial pathogens (alone) accounted for only five per cent and no enteric pathogens were found in 15 per cent of cases. Non-agglutinable rotavirus, presumably a different serotype, was seen in both gastroenteritis and control patients. Rotavirus ‘satellite’ particles previously undescribed were demonstrated in a number of stool samples.
9,941
Volume Contents Index
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9,942
ISAR News
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9,943
Contents of Veterinary Immunology and Immunopathology, Volume 112
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ISAR News
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9,945
Recent research in infectious disease()
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Recent research in infectious disease
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9,947
Volume Contents, Author and Subject Index for Vol. 42
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9,948
Author Index to Volume 31
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9,949
Neonatal bacterial infection: A changing scene?
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9,950
Antiviral activities of interferons
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IFC - Editorial Board / Publication Info
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Table of Contents from Journal of Psychosomatic Research
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A comparative analysis of the porcine, murine, and human immune systems
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Viruses demonstrated in children in Tanzania: Studies in diarrhoea and measles
Causes of diarrhoea with particular reference to viral agents were investigated in 123 infants and young children in Dar es Salaam, Tanzania. Twenty-six of the patients also had measles. Viruses were found in 52 of the 123 patients (43 per cent) and rotavirus occurred in 38 children (31 per cent). Enteroviruses were found in 10 patients, adenoviruses in nine and ‘small round virus’ in one (six patients had dual infection). Four patients died and only one of these children had viral particles in the stools. Breast milk formed part or all of the diet in 77 children (63 per cent) and virus isolation showed a similar pattern in breast fed infants and those not receiving breast milk. In 26 patients with measles only five were excreting viruses in their stools. Therefore no strong evidence was found to link the diarrhoea associated with measles in Tanzanian children to any particular virus. The pattern of virus infection causing infantile diarrhoea was similar in Dar es Salaam to other parts of the world.
9,955
Recent research in infectious disease
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9,956
Patent reports
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9,957
SUBJECT INDEX
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9,958
The Journal of Comparative Pathology Educational Trust and Petplan Charitable Trust Joint Research Award in Veterinary Pathology
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9,959
Master subject index
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9,960
Feedback
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9,961
Subject Index to Volume 65, issues 1 and 2
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9,962
Ocular and central nervous system involvement in non-effusive form of feline infectious peritonitis
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Related Elsevier virology titles contents alert
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9,964
Contents of volume 39
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9,965
Author index (vols. 2–3)
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9,966
Cumulative Subject Index for 2005
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9,967
Gene expression, virulence and vaccine development in coronaviruses
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9,968
V, 2.Ribosomal frameshifting in astroviruses
This chapter reviews ribosomal frameshifting with an emphasis on the frameshifting process in astroviruses. Frameshifting is a potential antiviral target. It is possible that the replication cycle of any virus that uses this process could be disrupted by modulation of frameshift efficiencies, but a better understanding of the occurrence and the molecular basis of frameshifting will be required before it can be considered a genuine target. To date, there are no confirmed examples of frameshift signals from conventional eukaryotic cellular genes, although computer-assisted database searches have identified a number of candidates. The frameshift allows the required ratio of viral proteins to be produced, but it may also serve to downregulate levels of viral replicases that may be toxic in high amounts.
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Development of a Cell-Based Assay for Identification of Viral Entry Inhibitors Against SARS-CoV by High Throughput Screening (HTS)
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Subject index (volume 5)
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9,971
Contents of volume 38
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Contents of volume 3
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4904391 Method and apparatus for removal of cells from bone marrow: Richard B Freeman
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Viral etiology of multiple sclerosis: where does the truth lie?
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I, 3. The enteric nervous system and infectious diarrhea
This chapter discusses the background knowledge about the enteric nervous system (ENS) as well as the role of ENS in secretory states of the small intestine. The chapter describes the anatomy and physiology of the ENS. A description of the experimental evidence for the involvement of ENS in secretory states of the gut, primarily in cholera toxin-induced secretion that is the most thoroughly investigated secretory state, is presented in the chapter. The chapter focuses on the involvement of ENS in rotavirus (RV) diarrhea. The involvement of the ENS in diarrhea pathophysiology opens up new potential sites of action for drugs in the treatment of intestinal secretory states. The chapter concludes with a discussion of the sites of action for the pharmacological treatment of diarrhea.
9,976
4904596 Hybridoma antibody (FH6) defining a human cancer-associated difucoganglioside: Sen-itiroh Hakomori assigned to Fred Hutchinson Cancer Research Center
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4904481 Method of conferring immuno-tolerance to a specific antigen: C Garrison Fathman assigned to The Board of Trustess of Leland Stanford University
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4902685 2-Amino-3-cyano-bicyclic pyridines/pyrazines as inhibitors of interleukin 1: Jerauld Skotnicki assigned to American Home Products Corporation
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Evaluation of Interferon Inducers, Ribavirin and Mouse Hyperimmune Serum in a Pathogenesis/Lethal Mouse Model Using a Mouse-adapted SARS-CoV
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9,980
Contents of volume 12
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Effects of the Addition of Hiltonol(®) (Poly-ICLC) to a SARS-CoV S Protein Vaccine in Lethal SARS-CoV Mouse Model
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19th ICAR Abstracts:
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5420253 Method for purifying egg yolk immunoglobulins : Emery Daryll A; Straub Darren E Willmar, MN, United States Assigned to Willmar Poultry Company Inc
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The role of pathogenic Escherichia coli in the etiology of veal calf hemorrhagic enteritis
Veal calf hemorrhagic enteritis, a condition that has no identified specific etiology, is a fatal syndrome of veal calves and has recently become a major concern of the veal calf industry in the midwestern United States. To determine the possible role of common enteric pathogens in this disease, 40 veal calves with hemorrhagic enteritis (cases) and 25 dairy calves diagnosed with enteric infection (control) were investigated. The veal calves were negative for several known enteric pathogens except for pathogenic Escherichia coli isolates that expressed multiple virulence attributes. To determine whether such isolates have a significant association with hemorrhagic enteritis in veal calves, we compared the prevalence of pathogenic E. coli in the 40 veal calves with the prevalence of similar E. coli in the dairy calves that were diagnosed with colibacillosis within the same season of the year. Escherichia coli isolates from the two groups of calves were tested for several properties of E. coli related to pathogenicity, i.e. production of verotoxins, heat-stable enterotoxin (ST(a)), heat-labile enterotoxin, enterohemolysin, K99 fimbrial antigens, hemagglutination activity, and attachment to Hep-2 tissue culture cells. Escherichia coli that produces ST(a) were more commonly isolated from veal calves with hemorrhagic enteritis (45%) than from dairy calves with enteritis (12%) (P<0.05). Various patterns of attachment of E. coli to Hep-2 tissue culture cells were studied. The E. coli that demonstrated aggregative patterns of attachment were more commonly represented in veal calves (32%) than in dairy calves (8%). We observed that there was no correlation between ST(a) production and K99 pili expression among the enterotoxigenic E. coli (ETEC) isolates that were recovered from veal calves. This may indicate the emergence of K99-negative ETEC, probably as a result of the wide use of K99-based vaccines.
9,985
Related elsevier virology titles contents alert
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Scientific program
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9,987
Epidemiologic approaches used in a herd health practice to investigate neonatal calf mortality
Epidemiologic methods were applied in an investigation into causes of neonatal mortality on a 1400-cow dairy in the southern San Joaquin Valley of California. A format for collation of information on birthdate and date of death was assembled into a matrix which improved conceptualization of the data and which simplified procedures for estimation of mortality rates. Contemporary and birth cohort life table methods, mortality density estimations and relative risk assessment were used to ascertain if there were high-risk groups of calves that could be identified by age, day-of-the-week born, day-of-the-week died and sex. During the outbreak of neonatal diarrhea on this dairy, female calves were found to have experienced an atypically higher rate of mortality (10.7%) than did males (5.3%). Calves of both sexes died between the ages of 9 and 19 days. In addition, the risk of dying was 11 times greater for calves born on Wednesdays than for those born on Saturdays. These findings formed the basis for recommended changes in management of neonatal calves on the dairy.
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P232 MOLECULAR PHYLOGENETICS OF HEPATITIS C VIRUS (HCV) AS A TOOL TO UNDERSTAND THE HCV EPIDEMIC IN BRITISH COLUMBIA (BC), CANADA
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Author index of volume 178 Supplement 1
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9,990
Cumulative Author Index for 2010
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9,991
High Throughput Screening of Protease Inhibitor Libraries Using a Novel Dual Pseudotype-Based Assay for SARS-CoV Entry
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9,992
P233 THE NATURAL COMPOUND PENTA-O-GALLOYL-GLUCOSE, DERIVED FROM THE ROOT CORTEX MOUTAN, EFFICIENTLY INHIBITS HEPATITIS C-VIRUS ENTRY AND SHOWS EXCELLENT PHARMACOKINETIC PERFORMANCE IN VIVO
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5424065 Vaccines containing avirulent phop-type microorganisms : Curtiss Roy;Galan Jorge St Louis, MO, United States Assigned to Washington University
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Contents of volume 71
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Contents of volume 35
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5013542 Method to inhibit adhesion of disease-causing microorganisms to teeth: Donald I Hay, Ronald J Gibbons, Edgard G Moreno assigned to Forsyth Dental Infirmary for Children
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9,997
The prevalence of some economically important swine diseases in farrowing units in southwestern Finland
The prevalence and geographical distribution of some economically important swine diseases were surveyed in 114 randomly selected farrowing units which had a contract with Southwestern Finland's Cooperative Slaughterhouse (LSO) for producing feeder pigs to be delivered to the all in-all out finishing units. The focus was on infectious diseases which could be transmitted to the finishing units with delivered growers, and which might have some influence on partial carcass condemnations (PCC) in meat inspection. Farm visits were done by a veterinarian (senior author) assisted by a technician. Colostrum samples (average 22 per herd) were taken in 100 herds, and analyzed for Actinobacillus pleuropneumoniae (A. pleur) and Mycoplasma hyopneumoniae (M.hyo) antibodies by enzyme-linked immunosorbent assays (ELISAs). Only nine of 114 herds were judged to be free of mange. It was concluded that all finishing units received mange-infected feeder pigs each time the unit was filled. One or more acute erysipelas outbreaks had occurred in every fifth herd during the previous year. The risk of a finishing unit receiving feeder pigs carrying erysipelas was considered to be high. Swine dysentery (Serpulina hyodysenteriae) was not found to be a problem in the LSO area. Clostridium perfringens type C enteritis was found in eight (7%) herds. Seven of these herds were located in those supply areas where the PCC percentage of feeder pigs was high. In spite of statistical connection no causality between this disease and PCC was presumed. There were no previous diagnoses of respiratory diseases but spontaneous coughing was observed in 5% of the herds. Provocation testing induced coughing in 22% of herds but not serious coughing in any herd. Managers had observed coughing in 15% of herds. Ninety-one herds were positive in a colostrum ELISA for A. pleur antibodies, and eight herds were positive for M.hyo antibodies. A.pleur-positive herds had several positive or samples suspected of being positive in each herd bu M.hyo-positive herds had only one or two positive or suspected samples per herd. Six of the M.hyo herds were located in the high PCC area, two in the average PCC area and none in the low PCC area. M.hyo was suggested to be one of the possible explanations for geographical variation of PCC. Atrophic rhinitis was not considered to be of importance in LSO.
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5017559 Agent for blocking nonspecific adsorption, process for preparing thereof and method of blocking nonspecific adsorption: Shunichi Dosako, Hiroshi Shinmoto, Saitamaken, Japan assigned to Snow Brand Milk Products Co Ltd
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9,999
Detection of foot-and-mouth disease virus infection-associated antigen antibodies: comparison of the enzyme-linked immunosorbent assay and agar gel immunodiffusion tests
A liquid-phase enzyme-linked immunosorbent assay (ELISA) was compared with the standard agar gel immunodiffusion test (AGID) to identify and quantify antibodies against foot-and-mouth disease (FMD) virus infection-associated (VIA) antigen. A total of 3181 cattle sera were tested. Of these sera, 1885 were from cattle which had not been exposed to FMD. A total of 1296 sera were either from cattle which were experimentally exposed to FMD virus or from cattle involved in field outbreaks. The results indicate that the ELISA has the same specificity as the AGID test, but is more efficient in detecting cattle exposed to FMD virus. The ELISA technique will probably prove to be a more satisfactory test in support of the prevention, control and eradication programs for the disease.