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{ "REASONING": [ "The QUESTION asks what is essential for the priority outcomes.", "The DOCUMENT states that 'Establishing durable international relationships that integrate diverse expertise is essential to delivering these outcomes.'", "The ANSWER provided is 'Establishing durable international relationships that integrate diverse expertise.'", "The ANSWER directly matches the information provided in the DOCUMENT without adding or contradicting any details." ], "SCORE": "PASS" }
PASS
1,851
{ "REASONING": [ "The DOCUMENT states that nasal swabs are randomly collected throughout the year.", "The DOCUMENT mentions that these swabs are tested by RT-PCR for influenza viruses.", "The ANSWER accurately reflects these points without adding or contradicting any information from the DOCUMENT." ], "SCORE": "PASS" }
PASS
594
{ "REASONING": [ "The provided answer states that experiments with the SL-SHC014-MA15 chimeric virus were restricted as gain of function (GOF) studies under the US government-mandated pause policy.", "The DOCUMENT confirms this by stating: 'Due to the elevated pathogenic activity of the SHC014-MA15 chimeric virus relative to MA15 chimeric virus with the original human SARS S gene in mice, such experiments with SL-SHC014-MA15 chimeric virus were later restricted as gain of function (GOF) studies under the US government-mandated pause policy.'", "The ANSWER does not introduce any new information or contradict the DOCUMENT." ], "SCORE": "PASS" }
PASS
630
{ "REASONING": [ "The DOCUMENT states that the efficacy of DAAs can be attenuated by the presence of resistance-associated substitutions (RASs) before and after treatment.", "The DOCUMENT provides detailed information on how RASs in the NS5A and NS5B regions of the Hepatitis C Virus can compromise the high response rates to DAAs.", "The ANSWER, 'the presence of resistance-associated substitutions,' directly aligns with the information provided in the DOCUMENT.", "The ANSWER does not introduce any new information or contradict the DOCUMENT." ], "SCORE": "PASS" }
PASS
353
{ "REASONING": [ "The QUESTION asks for the result of the Imperial College estimation.", "The DOCUMENT states that the Imperial College London estimated there had been 4000 (95% CI: 1000-9700) cases in Wuhan with symptoms onset by 18 January 2020, and the basic reproduction number (R0) was estimated at 2.6 (95% CI: 1.5-3.5).", "The ANSWER correctly states that there had been 4000 (95% CI: 1000-9700) cases in Wuhan with symptoms onset by 18 January 2020.", "The ANSWER also correctly mentions the basic reproduction number (R0) was estimated at 2.6 (95% CI: 1.5-3.5).", "The ANSWER does not introduce any new information or contradict the DOCUMENT." ], "SCORE": "PASS" }
PASS
1,907
{ "REASONING": [ "The DOCUMENT states that as of 26 January 2020, the outbreak had resulted in 2066 confirmed cases, with 618 of them in Wuhan.", "The DOCUMENT also states that there were 56 deaths, with 45 of them in Wuhan.", "The ANSWER states that there were 2066 confirmed cases and 56 deaths, but it incorrectly mentions that 50 of the deaths were in Wuhan." ], "SCORE": "FAIL" }
FAIL
1,905
{ "REASONING": [ "The provided answer states: 'The microbe occurs in most cases of the disease in question and under circumstances which can account for the pathological changes and clinical course of the disease.'", "The DOCUMENT states Koch's first postulate as: 'The microbe occurs in every case of the disease in question and under circumstances which can account for the pathological changes and clinical course of the disease.'", "The provided answer changes 'every case' to 'most cases,' which is a significant alteration of the original postulate.", "This change introduces new information that is not present in the DOCUMENT and contradicts the original statement." ], "SCORE": "FAIL" }
FAIL
822
{ "REASONING": [ "The DOCUMENT states that the substitution E62D is considered a secondary substitution.", "It mentions that E62D does not confer resistance by itself but, when combined with a known RAS, it confers a higher level of resistance than the one achieved by the RAS alone.", "The ANSWER accurately reflects this information by stating that E62D 'confers a higher level of resistance than the one achieved by the RAS alone'.", "The ANSWER does not introduce any new information or contradict the DOCUMENT." ], "SCORE": "PASS" }
PASS
360
{ "REASONING": [ "The DOCUMENT states that the index case, defined as the first identified case, was diagnosed on 1 February 2020.", "The ANSWER claims that the case was diagnosed on 2 February.", "This discrepancy means the ANSWER is not faithful to the DOCUMENT." ], "SCORE": "FAIL" }
FAIL
1,509
{ "REASONING": [ "The DOCUMENT states that Ae. albopictus became the main vector for CHIKV within 1-2 years after CHIKV was introduced to the Indian Ocean region.", "The ANSWER provided is Ae. aegypti, which contradicts the information in the DOCUMENT.", "The DOCUMENT clearly indicates that Ae. albopictus, not Ae. aegypti, became the main vector in the Indian Ocean region within the specified timeframe." ], "SCORE": "FAIL" }
FAIL
1,243
{ "REASONING": [ "The provided answer states that failure to wash hands can result in autoinfection and infection of patients hospitalized for other causes.", "The DOCUMENT supports this by mentioning that failure to wash hands between patients can result in autoinfection and infection of patients hospitalized for other causes.", "The answer does not introduce new information or contradict the DOCUMENT." ], "SCORE": "PASS" }
PASS
780
{ "REASONING": [ "The QUESTION asks about what happens to certain activities during infection.", "The DOCUMENT states that 'These activities take place in various subcellular compartments and are differentially regulated during infection.'", "The ANSWER provided is 'are differentially regulated'.", "The ANSWER is directly supported by the DOCUMENT and does not introduce new information or contradict the DOCUMENT." ], "SCORE": "PASS" }
PASS
1,830
{ "REASONING": [ "The DOCUMENT defines two seasons for identifying possible seasonal trends in virus circulation: winter season during weeks 23 to 39 between June and September, and summer season during the rest of the year.", "The ANSWER correctly states 'winter season during weeks 23 to 39 between June and September and summer season during the rest of the year.'", "The ANSWER does not introduce any new information or contradict the DOCUMENT." ], "SCORE": "PASS" }
PASS
600
{ "REASONING": [ "The DOCUMENT states that the index case, defined as the first identified case, is a passenger who started coughing from 19 January 2020 on board and was diagnosed on 1 February.", "The ANSWER correctly states that the case was diagnosed on 1 February.", "There is no contradiction or additional information in the ANSWER that is not present in the DOCUMENT." ], "SCORE": "PASS" }
PASS
1,509
{ "REASONING": [ "The DOCUMENT states that the membrane glycoproteins F and G sequences are used to define two major genotypes or groups, A and B.", "The ANSWER correctly identifies the two major genotypes of HMPV as A and B.", "There is no contradiction or additional information in the ANSWER that is not present in the DOCUMENT." ], "SCORE": "PASS" }
PASS
221
{ "REASONING": [ "The DOCUMENT states that efforts in neo-virology will unlock 'a vast wealth of currently unexplored biodiversity, leading to biotechnologies and treatments that leverage the host-virus interactions developed throughout evolution.'", "The ANSWER states that these efforts will unlock 'a vast wealth of currently unexplored biodiversity, leading to biotechnologies and treatments that leverage the host-virus interactions developed in recent decades.'", "The phrase 'developed in recent decades' in the ANSWER is not faithful to the DOCUMENT, which specifies 'developed throughout evolution.'", "The ANSWER introduces a time frame ('recent decades') that is not mentioned in the DOCUMENT." ], "SCORE": "FAIL" }
FAIL
1,848
{ "REASONING": [ "The QUESTION asks for the definition of 'SCA'.", "The DOCUMENT mentions 'sine-cosine algorithm (SCA)' in the context of swarm intelligence methods used to enhance the ANFIS model.", "The ANSWER provided is 'sine-cosine algorithm', which directly matches the acronym 'SCA' as mentioned in the DOCUMENT.", "The ANSWER does not introduce any new information or contradict the DOCUMENT." ], "SCORE": "PASS" }
PASS
517
{ "REASONING": [ "The DOCUMENT states that Arenaviruses have a bisegmented, negative-sense, single-stranded RNA genome with a unique ambisense coding strategy that produces just four known proteins.", "The four proteins mentioned in the DOCUMENT are: a glycoprotein, a nucleoprotein (NP), a matrix protein (Z), and a polymerase (L).", "The ANSWER lists the same four proteins: a glycoprotein, a nucleoprotein (NP), a matrix protein (Z), and a polymerase (L).", "The ANSWER does not introduce any new information or contradict the DOCUMENT." ], "SCORE": "PASS" }
PASS
380
{ "REASONING": [ "The DOCUMENT states that RBPs post-transcriptionally control the expression of crucial inflammatory factors in various tissues, not just immune cells.", "The ANSWER correctly mentions the post-transcriptional control of crucial inflammatory factors but incorrectly limits this to immune cells.", "The DOCUMENT also mentions the potential therapeutic applications of RBPs, which is correctly included in the ANSWER." ], "SCORE": "FAIL" }
FAIL
1,822
{ "REASONING": [ "The provided answer states that influenza viruses are 'even harder to reassort, recombine, and mutate in nature than many other RNA viruses.'", "The DOCUMENT actually states that 'influenza viruses are even easier to reassort, recombine, and mutate in nature than many other RNA viruses.'", "This is a direct contradiction of the information provided in the DOCUMENT." ], "SCORE": "FAIL" }
FAIL
2,010
{ "REASONING": [ "The DOCUMENT describes Acute Hemorrhagic Encephalomyelitis (AHEM) as a rare and extremely severe form of acute disseminated encephalomyelitis characterized by fulminant encephalopathy with hemorrhagic necrosis of the parenchyma of the central nervous system.", "The ANSWER states 'fulminant encephalopathy with hemorrhagic inflammation'.", "The term 'hemorrhagic inflammation' in the ANSWER is not explicitly mentioned in the DOCUMENT. The DOCUMENT specifically uses 'hemorrhagic necrosis' instead of 'hemorrhagic inflammation'.", "The ANSWER does not fully capture the severity and specific characteristics (hemorrhagic necrosis) described in the DOCUMENT." ], "SCORE": "FAIL" }
FAIL
200
{ "REASONING": [ "The DOCUMENT states that 'Ninety-five percent of infected adults are symptomatic after infection.'", "The DOCUMENT also mentions that 'most become disabled for weeks to months as a result of decreased dexterity, loss of mobility, and delayed reaction.'", "The ANSWER accurately reflects these points without adding new information or contradicting the DOCUMENT." ], "SCORE": "PASS" }
PASS
1,223
{ "REASONING": [ "The DOCUMENT emphasizes the importance of crisis-affected community engagement in pandemic planning to maximize the effectiveness of interventions.", "It also highlights the need for transparent and credible information-sharing mechanisms, diplomacy, and inclusive governance practices.", "While government-led initiatives may be part of the broader strategy, the DOCUMENT does not specifically state that they are integral in pandemic planning.", "The ANSWER does not directly reflect the key points made in the DOCUMENT about community engagement and tailored interventions." ], "SCORE": "FAIL" }
FAIL
1,999
{ "REASONING": [ "The DOCUMENT states that the causative organism of COVID-19 was identified within 4 weeks, by 26 January 2020, after the initial clustering of cases was noticed on 29 December 2019.", "The ANSWER states that it took 6 weeks to identify the cause of COVID-19.", "The ANSWER contradicts the information provided in the DOCUMENT, which clearly mentions a 4-week timeframe." ], "SCORE": "FAIL" }
FAIL
770
{ "REASONING": [ "The DOCUMENT states that EAP leaf extract is a prophylactic and immune enhancement agent against H5N1 influenza virus infection.", "The ANSWER claims that EAP leaf extract is a therapeutic and immune enhancement agent against H5N1 influenza virus infection.", "The term 'therapeutic' implies treatment after infection, whereas the DOCUMENT emphasizes the prophylactic (preventive) nature of EAP, administered before viral challenge.", "The DOCUMENT does not provide evidence that EAP is effective as a treatment after infection, only as a preventive measure." ], "SCORE": "FAIL" }
FAIL
139
{ "REASONING": [ "The DOCUMENT states that there has been a 25% decrease in the incidence of pneumonia, from 0.29 episodes per child year in low-and middle-income countries in 2000, to 0.22 episodes per child year in 2010.", "The ANSWER incorrectly states a 30% decrease in the incidence of pneumonia, from 0.29 episodes per child year in 2000, to 0.20 episodes per child year in 2010.", "The DOCUMENT mentions a 58% decrease in pneumonia-associated disability-adjusted life years between 1990 and 2013, which is correctly reflected in the ANSWER.", "The discrepancy in the percentage decrease in incidence (30% vs. 25%) and the incorrect endpoint value (0.20 vs. 0.22) in the ANSWER makes it unfaithful to the DOCUMENT." ], "SCORE": "FAIL" }
FAIL
107
{ "REASONING": [ "The DOCUMENT mentions that isocitrate lyase is essential for the metabolism of fatty acids in the context of mycobacteria.", "The ANSWER provided is 'isocitrate lyase'.", "The ANSWER does not contradict the information provided in the DOCUMENT.", "The ANSWER does not offer new information beyond the context provided in the DOCUMENT." ], "SCORE": "PASS" }
PASS
349
{ "REASONING": [ "The QUESTION asks for the number of ventilators projected to be required for a pandemic in the United States according to past studies.", "The DOCUMENT states: 'In scenarios that used clinical attack rates of 20% to 30%... an estimated 35,000 to 60,000 ventilators would be needed.'", "The ANSWER provided is '35,000 to 60,000'.", "The ANSWER is directly supported by the information in the DOCUMENT and does not introduce any new information or contradict the DOCUMENT." ], "SCORE": "PASS" }
PASS
94
{ "REASONING": [ "The DOCUMENT states that detectable 2019-nCoV viral RNA in blood is a strong indicator for further clinical severity.", "The DOCUMENT also mentions that the presence of viral RNA outside of the respiratory tract might herald the severity of the disease and alarm the requirement of special care.", "The ANSWER correctly states that the presence of viral RNA outside of the respiratory tract might herald the severity of the disease and alarm the requirement of special care.", "The ANSWER does not introduce new information or contradict the DOCUMENT." ], "SCORE": "PASS" }
PASS
1,469
{ "REASONING": [ "The DOCUMENT describes the use of the MTT assay to measure the inhibition of viral replication by patchouli alcohol.", "The DOCUMENT does not mention the use of a plaque assay method for measuring viral replication inhibition.", "The ANSWER 'Plaque assay method' is not supported by the information provided in the DOCUMENT." ], "SCORE": "FAIL" }
FAIL
334
{ "REASONING": [ "The DOCUMENT states that 'these infections causes are identified in less than 50%'.", "The ANSWER claims 'more than 50%', which directly contradicts the information provided in the DOCUMENT." ], "SCORE": "FAIL" }
FAIL
585
{ "REASONING": [ "The DOCUMENT states that the assay was done at different temperatures: 32uC, 37uC, and 42uC.", "The ANSWER lists the temperatures as 32uC, 36uC, and 42uC.", "The temperature 36uC mentioned in the ANSWER does not match any temperature mentioned in the DOCUMENT.", "The correct temperature from the DOCUMENT is 37uC, not 36uC." ], "SCORE": "FAIL" }
FAIL
71
{ "REASONING": [ "The DOCUMENT states that 'the total volume of inbound passengers from China was m = 63.1 million per year in 2017, of which 100q = 2.1% were from Wuhan.'", "The ANSWER provided is '2.1%', which directly matches the percentage mentioned in the DOCUMENT.", "There is no additional information or contradiction in the ANSWER compared to the DOCUMENT." ], "SCORE": "PASS" }
PASS
1,516
{ "REASONING": [ "The DOCUMENT states that the 'Never Event' policy was implemented by the Centers for Medicare & Medicaid of the United States of America in 2008.", "The DOCUMENT specifies that under this policy, hospitals would no longer receive higher payments for the additional costs associated with treating patients for certain healthcare-acquired infections, including those related to CABG.", "The ANSWER correctly states that hospitals would no longer receive higher payments for the additional costs associated with treating patients for certain healthcare-acquired infections.", "The ANSWER does not introduce any new information or contradict the DOCUMENT." ], "SCORE": "PASS" }
PASS
369
{ "REASONING": [ "The QUESTION asks for the year of the first SARS epidemic.", "The DOCUMENT mentions the 'SARS epidemic of 2002/3' indicating that the first SARS epidemic occurred around 2002-2003.", "The ANSWER provided is 'rapid and transparent sharing of information within countries and agencies,' which does not address the QUESTION about the year of the first SARS epidemic.", "The ANSWER is not faithful to the DOCUMENT as it does not provide the correct information related to the QUESTION." ], "SCORE": "FAIL" }
FAIL
767
{ "REASONING": [ "The DOCUMENT states that the SL-SHC014-MA15 virus could indeed efficiently use human ACE2 and replicate in primary human airway cells to similar titres as epidemic strains of SARS-CoV.", "The ANSWER incorrectly states that the SL-SHC014-MA15 virus could replicate to higher titres than epidemic strains of SARS-CoV, which is not supported by the DOCUMENT.", "The DOCUMENT mentions that while SL-SHC014-MA15 can replicate efficiently in young and aged mouse lungs, infection was attenuated, and less virus antigen was present in the airway epithelium as compared to SARS MA15.", "The ANSWER correctly reflects the information about the replication efficiency in mouse lungs and the attenuation of infection compared to SARS MA15." ], "SCORE": "FAIL" }
FAIL
629
{ "REASONING": [ "The DOCUMENT explicitly states that the study excludes cases reported in the United Kingdom (UK).", "The ANSWER provided is 'France', which is incorrect based on the DOCUMENT.", "The DOCUMENT includes data from France and does not exclude it from the study." ], "SCORE": "FAIL" }
FAIL
1,765
{ "REASONING": [ "The DOCUMENT states that 'Coinfection was observed in 4.1% of cases.'", "The ANSWER provided is '4.1% of cases.'", "The ANSWER directly matches the information given in the DOCUMENT without adding or contradicting any details." ], "SCORE": "PASS" }
PASS
228
{ "REASONING": [ "The DOCUMENT states that latrines in crisis settings are often shared and distant from residential shelters.", "The ANSWER claims that latrines in crisis settings are often shared and close to residential shelters.", "The ANSWER directly contradicts the information provided in the DOCUMENT." ], "SCORE": "FAIL" }
FAIL
1,997
{ "REASONING": [ "The QUESTION asks about the reduction in bacterial pneumonia under the revised WHO definition.", "The ANSWER provides specific vaccine efficacy percentages for the 10-valent and 13-valent pneumococcal conjugate vaccines in preventing presumed bacterial pneumonia.", "The DOCUMENT states that the revised definition of 'presumed bacterial pneumonia' includes WHO-defined alveolar consolidation, other abnormal chest radiograph infiltrates, and a serum C-reactive protein of at least 40 mg/L.", "The DOCUMENT also provides the same vaccine efficacy percentages for the 10-valent and 13-valent pneumococcal conjugate vaccines as mentioned in the ANSWER.", "The ANSWER does not introduce any new information or contradict the DOCUMENT." ], "SCORE": "PASS" }
PASS
118
{ "REASONING": [ "The DOCUMENT states that acute necrotizing encephalopathy (ANE) could be triggered by a viral infection in previously healthy children.", "There is no mention in the DOCUMENT that bacterial infections are a trigger for ANE.", "The provided ANSWER incorrectly states that bacterial infection in previously healthy children could trigger ANE, which is not supported by the DOCUMENT." ], "SCORE": "FAIL" }
FAIL
204
{ "REASONING": [ "The DOCUMENT states that 'Without the adaptation of existing standards, mitigation plans will fall short of health and human rights obligations in outbreak response.'", "The ANSWER directly reflects this statement from the DOCUMENT.", "The ANSWER does not introduce any new information or contradict the DOCUMENT." ], "SCORE": "PASS" }
PASS
2,000
{ "REASONING": [ "The DOCUMENT states that the hosts were divided into four compartments: susceptible hosts (S H ), exposed hosts (E H ), infected hosts (I H ), and removed hosts (R H ).", "The ANSWER incorrectly states that the hosts were divided into five compartments, including 'recovered hosts (R H )'.", "The term 'recovered hosts' is not mentioned in the DOCUMENT; instead, 'removed hosts (R H )' includes both recovered and dead hosts." ], "SCORE": "FAIL" }
FAIL
1,486
{ "REASONING": [ "The DOCUMENT mentions Staphylococcus aureus (S. aureus) as a Gram positive bacteria.", "The ANSWER states that Staph aureus is a Gram negative bacteria.", "This directly contradicts the information provided in the DOCUMENT." ], "SCORE": "FAIL" }
FAIL
1,036
{ "REASONING": [ "The DOCUMENT states that dendritic cells (DCs) naturally exist in the gut-associated lymphoid tissue (GALT).", "The GALT includes Peyer's patches (PPs), isolated lymphoid follicles (ILFs), mesenteric lymph nodes (MLNs), and is scattered throughout the subepithelial lamina propria (LP) of the small intestine and colon.", "The ANSWER provided is 'gut-associated lymphoid tissue (GALT)', which is a direct reference to the information given in the DOCUMENT.", "The ANSWER does not introduce any new information or contradict the DOCUMENT." ], "SCORE": "PASS" }
PASS
759
{ "REASONING": [ "The DOCUMENT states that the genome of 2019-nCoV has 89% nucleotide identity with bat SARS-like-CoVZXC21 and 82% with human SARS-CoV.", "The ANSWER incorrectly states that the genome of 2019-nCoV has 85% nucleotide identity with bat SARS-like-CoVZXC21 and 80% with human SARS-CoV.", "The phylogenetic trees clustering information provided in the ANSWER is consistent with the DOCUMENT.", "However, the incorrect nucleotide identity percentages in the ANSWER contradict the DOCUMENT." ], "SCORE": "FAIL" }
FAIL
1,913
{ "REASONING": [ "The DOCUMENT states that Liew validated one multiplex ELISA for the detection of 9 antigens.", "The QUESTION specifically asks about the number of antigens detected by Liew's multiplex ELISA test.", "The ANSWER provided is '8', which does not match the information in the DOCUMENT.", "The correct number of antigens detected by Liew's multiplex ELISA test, according to the DOCUMENT, is 9." ], "SCORE": "FAIL" }
FAIL
44
{ "REASONING": [ "The DOCUMENT discusses the importance of community-based surveillance for enhancing public health efforts and scientific understanding of respiratory infections.", "It highlights that clinical data alone may not capture the full picture of disease incidence in the general population.", "The study suggests that community surveillance can provide valuable information that is not represented in clinical data.", "The term 'passive community surveillance' is not explicitly mentioned in the DOCUMENT." ], "SCORE": "FAIL" }
FAIL
265
{ "REASONING": [ "The provided answer lists the main challenges as: (1) early identification of outbreak, (2) rapid expansion of patients, (3) high risk of nosocomial transmission, (4) unpredictability of size impacted, and (5) lack of backup resource.", "The DOCUMENT mentions these exact challenges in the text: 'The main challenge may include (1) early identification of outbreak, (2) rapid expansion of patients, (3) high risk of nosocomial transmission, (4) unpredictability of size impacted, and (5) lack of backup resource.'", "The ANSWER does not introduce any new information or contradict the DOCUMENT." ], "SCORE": "PASS" }
PASS
537
{ "REASONING": [ "The DOCUMENT states that 'up to an estimated 7.3 billion surgical masks or respirators would be required' for a pandemic in the United States.", "The ANSWER provided is 'an estimated 7.5 billion'.", "The ANSWER overestimates the number of surgical masks or respirators required compared to the DOCUMENT." ], "SCORE": "FAIL" }
FAIL
85
{ "REASONING": [ "The DOCUMENT states that among the 38 cases studied, 25 were male.", "The ANSWER '24' does not match the information provided in the DOCUMENT.", "The correct number of male cases is 25, not 24." ], "SCORE": "FAIL" }
FAIL
1,761
{ "REASONING": [ "The DOCUMENT clearly states that the study aimed to estimate the TB prevalence in Shandong province, not the entire country of China.", "The study also aimed to compare the results of the 2010 survey with the 2000 survey and to compare yields of TB cases from different case finding approaches.", "The ANSWER provided is too broad and does not accurately reflect the specific focus of the study as described in the DOCUMENT." ], "SCORE": "FAIL" }
FAIL
54
{ "REASONING": [ "The DOCUMENT states that 'Coronavirus OC43 was the most common virus detected in community members (13.3%, 10/75)'.", "The ANSWER provided is 'Coronavirus OC43'.", "The ANSWER does not introduce any new information or contradict the DOCUMENT." ], "SCORE": "PASS" }
PASS
256
{ "REASONING": [ "The DOCUMENT states that the first death in France was reported on 15 February.", "The ANSWER correctly states the date as 15 February.", "There is no contradiction or additional information in the ANSWER that is not present in the DOCUMENT." ], "SCORE": "PASS" }
PASS
1,771
{ "REASONING": [ "The provided answer states that the 10-valent pneumococcal conjugate vaccine had a vaccine efficacy of 32% in preventing presumed bacterial pneumonia in young children in South America.", "The document actually states that the 10-valent pneumococcal conjugate vaccine had a vaccine efficacy of 22% in preventing presumed bacterial pneumonia in young children in South America.", "The provided answer states that the 13-valent pneumococcal conjugate vaccine had a vaccine efficacy of 49% in preventing presumed bacterial pneumonia in children older than 16 weeks who were not infected with HIV in South Africa.", "The document actually states that the 13-valent pneumococcal conjugate vaccine had a vaccine efficacy of 39% in preventing presumed bacterial pneumonia in children older than 16 weeks who were not infected with HIV in South Africa.", "Both efficacy percentages provided in the answer are incorrect when compared to the document." ], "SCORE": "FAIL" }
FAIL
118
{ "REASONING": [ "The DOCUMENT explicitly states that the widespread use of pneumococcal conjugate vaccination and Haemophilus influenzae type B conjugate vaccination has decreased the incidence of radiologic pneumonia.", "The ANSWER directly reflects this information without adding any new details or contradicting the DOCUMENT." ], "SCORE": "PASS" }
PASS
115
{ "REASONING": [ "The DOCUMENT states that the survey was conducted by survey teams consisting of clinicians, public health doctors, radiologists, laboratory technicians, and nurses.", "The ANSWER includes 'epidemiologists,' which is not mentioned in the DOCUMENT.", "The inclusion of 'epidemiologists' introduces new information not supported by the DOCUMENT." ], "SCORE": "FAIL" }
FAIL
62
{ "REASONING": [ "The DOCUMENT mentions that a research article by Corman et al. discusses the development of a diagnostic methodology based on RT-PCR of the E and RdRp genes.", "The ANSWER states that the genes targeted for the diagnostic RT-PCR tests in 2019-nCoV are the E and RdRp genes.", "There is no contradiction between the ANSWER and the DOCUMENT.", "The ANSWER does not offer new information beyond the context provided in the DOCUMENT." ], "SCORE": "PASS" }
PASS
1,960
{ "REASONING": [ "The ANSWER states that all 6 patients with detectable viral RNA in the blood cohort progressed to severe symptom stage, indicating a strong correlation of serum viral RNA with disease severity (p-value = 0.0001).", "The DOCUMENT confirms this by stating: 'all of the 6 patients with detectable viral RNA in the blood cohort progressed to severe symptom stage, indicating a strong correlation of serum viral RNA with the disease severity (p-value = 0.0001)'.", "The ANSWER also mentions that 8 of the 11 patients with anal swab virus-positive were in severe clinical stage.", "The DOCUMENT supports this by stating: '8 of the 11 patients with anal swab virus-positive was in severe clinical stage'.", "The ANSWER does not introduce any new information or contradict the DOCUMENT." ], "SCORE": "PASS" }
PASS
1,466
{ "REASONING": [ "The DOCUMENT states that ILI is not specific to influenza and highlights the importance of having biological results to establish the differential diagnosis and explain the etiology of symptoms.", "The ANSWER incorrectly claims that ILI is specific to influenza and that it is not essential to have biological results, which directly contradicts the findings and conclusions presented in the DOCUMENT." ], "SCORE": "FAIL" }
FAIL
610
{ "REASONING": [ "The DOCUMENT states that nuclear receptors (NRs) are a class of ligand-inducible transcription factors.", "The ANSWER provided is 'class of ligand-inducible transcription factors'.", "The ANSWER is a direct extraction from the DOCUMENT and does not introduce any new information or contradict the DOCUMENT." ], "SCORE": "PASS" }
PASS
302
{ "REASONING": [ "The DOCUMENT discusses the design, synthesis, and evaluation of 1-substituted pyridylimidazo[1,5-a]pyridine derivatives as potent inhibitors of papain-like cysteine proteases.", "The ANSWER mentions '1-substituted pyridylimidazo[1,5-b]pyridine derivatives,' which is a different chemical structure from what is described in the DOCUMENT.", "The correct structure according to the DOCUMENT is '1-substituted pyridylimidazo[1,5-a]pyridine derivatives,' not '1,5-b'.", "This discrepancy means the ANSWER is not faithful to the DOCUMENT as it introduces incorrect information." ], "SCORE": "FAIL" }
FAIL
73
{ "REASONING": [ "The QUESTION asks for the prevalence of Coronavirus OC43 in community samples in Ilorin, Nigeria.", "The DOCUMENT states: 'The most common virus detected in community members (13.3%, 10/75).' and 'Coronavirus OC43 was the most common virus detected in community members (13.3%, 10/75).' ", "The ANSWER provided is '13.3% (95% CI 6.9-23.6%)'.", "The DOCUMENT confirms the prevalence of Coronavirus OC43 in community samples as 13.3% with a 95% confidence interval of 6.9-23.6%.", "The ANSWER does not introduce any new information or contradict the DOCUMENT." ], "SCORE": "PASS" }
PASS
262
{ "REASONING": [ "The QUESTION asks for the test used to determine the level of cytotoxicity in the study.", "The DOCUMENT mentions that the cytotoxicity of patchouli alcohol on MDCK cells was assessed by the MTT method.", "The ANSWER provided is 'CC 50', which is a value representing the concentration at which 50% of cells are viable, but it is not the name of the test used.", "The correct answer should be 'MTT assay' as per the DOCUMENT." ], "SCORE": "FAIL" }
PASS
333
{ "REASONING": [ "The QUESTION asks for the male to female ratio for the study.", "The DOCUMENT provides the male to female ratio for the entire study population as 1.82:1 (7361 males to 4038 females).", "The ANSWER given is 1.82:1.", "The ANSWER matches the information provided in the DOCUMENT." ], "SCORE": "PASS" }
PASS
214
{ "REASONING": [ "The DOCUMENT states that 'On 12 January 2020, Chinese authorities shared the sequence of a novel coronavirus termed severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)'.", "The ANSWER provided is '12 January 2020'.", "The ANSWER is directly supported by the information in the DOCUMENT and does not contradict it." ], "SCORE": "PASS" }
PASS
1,763
{ "REASONING": [ "The DOCUMENT states that the general difference between the two settings was that those from the hospital had severe illnesses, while those from the community were generally 'healthy' but exhibiting ARI symptoms (i.e., mild illness).", "The ANSWER claims 'decreased severity of illness in the clinical sample,' which directly contradicts the DOCUMENT's information that clinical cases had increased severity of illness." ], "SCORE": "FAIL" }
FAIL
264
{ "REASONING": [ "The DOCUMENT clearly states that the proposed model is an improved adaptive neuro-fuzzy inference system (ANFIS) using an enhanced flower pollination algorithm (FPA) by using the salp swarm algorithm (SSA).", "The ANSWER incorrectly mentions 'enhanced particle swarm optimization (PSO) algorithm' instead of 'enhanced flower pollination algorithm (FPA)'.", "The DOCUMENT does not mention the use of PSO in the proposed model; it specifically mentions FPA enhanced by SSA.", "Therefore, the ANSWER is not faithful to the DOCUMENT as it introduces incorrect information." ], "SCORE": "FAIL" }
FAIL
502
{ "REASONING": [ "The DOCUMENT states: 'it is estimated that approximately 20% of HIV-infected individuals living in the United States remain undiagnosed.'", "The ANSWER provided is '20%', which directly matches the percentage mentioned in the DOCUMENT.", "The ANSWER does not introduce any new information or contradict the DOCUMENT." ], "SCORE": "PASS" }
PASS
339
{ "REASONING": [ "The DOCUMENT explicitly states that the RVDSS collects, collates, and reports weekly data on the number of tests performed and the number of specimens confirmed positive for influenza, respiratory syncytial virus (RSV), para-influenza virus (PIV), and adenovirus.", "The ANSWER correctly includes influenza, RSV, and PIV.", "The ANSWER incorrectly includes rhinovirus, which is not mentioned in the DOCUMENT as being monitored by the RVDSS.", "The ANSWER omits adenovirus, which is mentioned in the DOCUMENT as being monitored by the RVDSS." ], "SCORE": "FAIL" }
FAIL
287
{ "REASONING": [ "The DOCUMENT states that pneumonia deaths decreased from 1.8 million in 2000 to 900,000 in 2013.", "The ANSWER incorrectly states that pneumonia deaths decreased to 800,000 in 2013.", "The ANSWER is not faithful to the DOCUMENT as it provides an incorrect figure for the reduction in pneumonia deaths." ], "SCORE": "FAIL" }
FAIL
108
{ "REASONING": [ "The DOCUMENT states that 2019-nCoV was believed to be transmitted through the respiratory tract and induced pneumonia.", "The DOCUMENT also mentions that 2019-nCoV can be transmitted through the oral-fecal route by infecting intestines.", "The ANSWER only mentions the respiratory transmission and the induction of pneumonia, which is consistent with part of the DOCUMENT.", "However, the ANSWER omits the information about the potential oral-fecal transmission route, which is also highlighted in the DOCUMENT." ], "SCORE": "FAIL" }
PASS
1,745
{ "REASONING": [ "The ANSWER states that 2019-nCoV is a novel lineage B Betacoronavirus closely related to bat SARS-related coronaviruses, which is consistent with the DOCUMENT.", "The ANSWER mentions that 2019-nCoV has unique genomic features that deserve further investigation to understand their roles in viral replication and pathogenesis, which aligns with the DOCUMENT.", "The ANSWER highlights the importance of more animal sampling to determine the natural animal reservoir and intermediate animal host, which is also emphasized in the DOCUMENT.", "The ANSWER notes that understanding the evolutionary history of 2019-nCoV is important, similar to the DOCUMENT's discussion on the evolutionary history and zoonotic nature of the virus." ], "SCORE": "PASS" }
PASS
1,957
{ "REASONING": [ "The DOCUMENT states that past studies projected an estimated 35,000 to 60,000 ventilators would be needed for a pandemic in the United States.", "The ANSWER provided is 45,000 to 70,000 ventilators.", "The upper limit of the ANSWER (70,000) exceeds the upper limit provided in the DOCUMENT (60,000).", "The lower limit of the ANSWER (45,000) is within the range provided in the DOCUMENT (35,000 to 60,000).", "The ANSWER is not fully faithful to the DOCUMENT as it introduces a higher upper limit not supported by the DOCUMENT." ], "SCORE": "FAIL" }
FAIL
94
{ "REASONING": [ "The DOCUMENT clearly states that the HMPV genome comprises eight open reading frames (ORFs).", "The ANSWER provided is 'seven', which contradicts the information in the DOCUMENT.", "The ANSWER is not faithful to the DOCUMENT as it provides incorrect information about the number of ORFs in the HMPV genome." ], "SCORE": "FAIL" }
FAIL
220
{ "REASONING": [ "The DOCUMENT explicitly states that 'to make molecular docking study feasible, a reliable 3D (three dimensional) structure of the target protein is the prerequisite condition.'", "The ANSWER provided is 'a reliable 3D (three dimensional) structure of the target protein,' which directly matches the information given in the DOCUMENT.", "There is no additional information or contradiction in the ANSWER compared to the DOCUMENT." ], "SCORE": "PASS" }
PASS
305
{ "REASONING": [ "The DOCUMENT states that all imported cases had a history of travel to China.", "There is no mention in the DOCUMENT of imported cases having a history of travel to Italy.", "The ANSWER contradicts the information provided in the DOCUMENT." ], "SCORE": "FAIL" }
FAIL
1,799
{ "REASONING": [ "The provided answer states that participants from outside Hubei province were associated with a lower risk of experiencing symptoms of distress compared with those in Wuhan.", "This information is directly supported by the DOCUMENT, which mentions: 'Multivariable logistic regression analysis showed participants from outside Hubei province were associated with lower risk of experiencing symptoms of distress compared with those in Wuhan (odds ratio [OR], 0.62; 95% CI, 0.43-0.88; P = .008)'.", "The answer does not introduce any new information or contradict the DOCUMENT." ], "SCORE": "PASS" }
PASS
466
{ "REASONING": [ "The QUESTION asks for the estimated number of tuberculosis cases in China in 2010.", "The DOCUMENT states that the estimated prevalence of all TB cases in China in 2010 was 108 per 100,000.", "The ANSWER provided is '108 per 100,000', which directly matches the information given in the DOCUMENT." ], "SCORE": "PASS" }
PASS
52
{ "REASONING": [ "The DOCUMENT states that the Imperial College London estimated there had been 4000 (95% CI: 1000-9700) cases in Wuhan with symptoms onset by 18 January 2020.", "The ANSWER incorrectly states that there had been 5000 (95% CI: 2000-10000) cases in Wuhan with symptoms onset by 18 January 2020.", "The DOCUMENT states that the basic reproduction number (R0) was estimated at 2.6 (95% CI: 1.5-3.5).", "The ANSWER incorrectly states that the basic reproduction number (R0) was estimated at 2.8 (95% CI: not provided).", "The ANSWER provides values that are not consistent with the values given in the DOCUMENT." ], "SCORE": "FAIL" }
FAIL
1,907
{ "REASONING": [ "The DOCUMENT clearly states that 'All 50 states have reported cases of COVID-19 to CDC.'", "The ANSWER provided is '49', which contradicts the information in the DOCUMENT.", "The ANSWER is not faithful to the DOCUMENT as it does not accurately reflect the number of states that have reported cases of COVID-19." ], "SCORE": "FAIL" }
FAIL
1,300
{ "REASONING": [ "The DOCUMENT explicitly mentions that 'multiplex reverse transcriptase polymerase chain reaction (RT-PCR)' has been developed to identify several viruses simultaneously.", "The ANSWER states 'multiplex polymerase chain reaction (PCR)', which is a simplified version of the term used in the DOCUMENT.", "While the ANSWER omits 'reverse transcriptase' from the full term 'multiplex reverse transcriptase polymerase chain reaction (RT-PCR)', it does not introduce new information or contradict the DOCUMENT.", "The core concept of using a multiplex PCR method to identify multiple viruses simultaneously is consistent between the ANSWER and the DOCUMENT." ], "SCORE": "PASS" }
FAIL
597
{ "REASONING": [ "The DOCUMENT states that the study highlights a substantial circulation of multiple respiratory pathogens in Réunion Island throughout the year, not just during the winter season.", "The ANSWER incorrectly specifies that the circulation of multiple pathogens occurs during the winter season, which is not supported by the DOCUMENT.", "The DOCUMENT mentions that different pathogens circulate in different seasons, with some being specific to summer and others to winter, but it does not limit the circulation of multiple pathogens to the winter season alone." ], "SCORE": "FAIL" }
FAIL
609
{ "REASONING": [ "The DOCUMENT lists the following viruses against which gemcitabine has antiviral activity: Middle East respiratory syndrome coronavirus (MERS-CoV), severe acute respiratory syndrome coronavirus (SARS-CoV), Zika virus (ZIKV), HCV, poliovirus (PV), influenza A virus (IAV), HIV, and enteroviruses (EV).", "The ANSWER correctly includes MERS-CoV, SARS-CoV, ZIKV, HCV, PV, HIV, and EV.", "The ANSWER incorrectly includes influenza B virus (IBV), which is not mentioned in the DOCUMENT.", "The DOCUMENT mentions influenza A virus (IAV), not influenza B virus (IBV)." ], "SCORE": "FAIL" }
FAIL
166
{ "REASONING": [ "The DOCUMENT states that PEDV 'damages the host intestine mucosal surfaces by infecting the intestine epithelial cells.'", "The ANSWER specifies 'intestine epithelial cells' as the cells infected by the PED virus.", "The ANSWER does not introduce any new information or contradict the DOCUMENT." ], "SCORE": "PASS" }
PASS
754
{ "REASONING": [ "The provided answer states that a clinical attack rate is 'the proportion of individuals who become ill with a disease in a population initially uninfected.'", "The DOCUMENT defines a clinical attack rate as 'the proportion of individuals who become ill with or die from a disease in a population initially uninfected.'", "The provided answer omits the part about individuals who die from the disease, which is included in the DOCUMENT's definition." ], "SCORE": "FAIL" }
FAIL
91
{ "REASONING": [ "The DOCUMENT states that 'the epidemic curve of a total of 199 confirmed cases was drawn'.", "It also mentions '199 symptomatic cases have been diagnosed on board as of 24 February'.", "The ANSWER states '200', which is not consistent with the '199' confirmed cases mentioned in the DOCUMENT." ], "SCORE": "FAIL" }
FAIL
1,505
{ "REASONING": [ "The DOCUMENT does not mention 'young foals and broodmares' as the primary groups affected by ECoV outbreaks in the USA.", "The DOCUMENT states that outbreaks mainly occurred among adult riding, racing, and show horses in the USA.", "The provided ANSWER introduces new information not supported by the DOCUMENT." ], "SCORE": "FAIL" }
FAIL
277
{ "REASONING": [ "The DOCUMENT describes the evaluation of the HIV-1 RT-LAMP assay.", "The METHODOLOGY/SIGNIFICANT FINDINGS section explicitly states that the study evaluated the HIV-1 RT-LAMP assay.", "The CONCLUSION section reiterates that the RT-LAMP isothermal amplification method was used in the study.", "The ANSWER provided is 'HIV-1 RT-LAMP assay', which directly matches the information given in the DOCUMENT." ], "SCORE": "PASS" }
PASS
337
{ "REASONING": [ "The DOCUMENT states that SARS-CoV infected about 8000 people and resulted in the deaths of approximately 10% of those infected.", "The ANSWER provided is '10%', which matches the information given in the DOCUMENT.", "There is no contradiction or additional information in the ANSWER that is not present in the DOCUMENT." ], "SCORE": "PASS" }
PASS
907
{ "REASONING": [ "The QUESTION asks for the prevalence rate in Shandong in 2010 for sputum positive cases of tuberculosis.", "The DOCUMENT provides the crude prevalence rate in Shandong in 2010 of sputum positive cases as 22.1 (95% CI: 9.6-34.6) per 100,000 in the adult population.", "The ANSWER given is 22.1, which matches the crude prevalence rate provided in the DOCUMENT." ], "SCORE": "PASS" }
PASS
66
{ "REASONING": [ "The DOCUMENT states that the time from symptom onset to hospitalisation/case isolation was about 3 days longer for locally acquired cases than for imported cases.", "The ANSWER accurately reflects this information without adding new details or contradicting the DOCUMENT." ], "SCORE": "PASS" }
PASS
1,797
{ "REASONING": [ "The QUESTION asks for immune factors associated with increased SARS-CoV morbidity and mortality.", "The DOCUMENT states that 'Immune factors that increased mortality for SARS-CoV were a higher neutrophil count and low T-cell counts.'", "The ANSWER provided is 'a higher neutrophil count and low T-cell counts.'", "The ANSWER directly matches the information provided in the DOCUMENT without adding or contradicting any details." ], "SCORE": "PASS" }
PASS
927
{ "REASONING": [ "The QUESTION asks about the vectors of Chikungunya virus in Asia.", "The DOCUMENT states: 'In Asia, the disease is vectored by Ae. aegypti and Ae. albopictus.'", "The ANSWER provided is 'Ae. aegypti and Ae. albopictus.'", "The ANSWER matches the information given in the DOCUMENT without adding or contradicting any details." ], "SCORE": "PASS" }
PASS
1,207
{ "REASONING": [ "The provided answer states that viral RNA polymerisation and reverse transcription enhance viral infectivity by allowing virus genome sizes to increase and incorporate new information.", "The DOCUMENT, however, states that these processes restrict viral infectivity by strongly limiting virus genome sizes and their incorporation of new information.", "The provided answer contradicts the information in the DOCUMENT." ], "SCORE": "FAIL" }
FAIL
1,811
{ "REASONING": [ "The DOCUMENT describes a study that involves the genomic characterization of the 2019 novel human-pathogenic coronavirus (2019-nCoV).", "The study includes bioinformatics analysis of a virus genome from a patient with 2019-nCoV infection.", "The study compares the 2019-nCoV genome with other related coronavirus genomes.", "The ANSWER accurately reflects the main activities described in the DOCUMENT." ], "SCORE": "PASS" }
PASS
1,912
{ "REASONING": [ "The provided answer 'compare the antiviral activity of CQ versus HCQ, the dose-response curves' is a fragment and does not fully address the question.", "The DOCUMENT provides detailed information on the comparison of antiviral activity between CQ and HCQ against SARS-CoV-2, including specific data on EC50 values, selectivity index, and mechanisms of action.", "The answer does not contradict the DOCUMENT but is incomplete and lacks the necessary detail to be considered faithful to the DOCUMENT." ], "SCORE": "FAIL" }
PASS
454
{ "REASONING": [ "The ANSWER lists the symptoms reported by the 29 symptomatic cases.", "The DOCUMENT confirms that 20 reported fever, 14 reported cough, and 8 reported weakness.", "The DOCUMENT also lists additional symptoms: headaches (6 cases), sore throat (2), rhinorrhoea (2), shortness of breath (2), myalgia (1), diarrhoea (1), and nausea (1).", "The ANSWER does not introduce any new information or contradict the DOCUMENT." ], "SCORE": "PASS" }
PASS
1,755
{ "REASONING": [ "The DOCUMENT states that 'patients with underlying medical conditions and the elderly are more likely to become severely ill, require hospitalization, and ultimately die.'", "The ANSWER 'patients with underlying medical conditions and the elderly' directly reflects this information.", "The ANSWER does not introduce any new information or contradict the DOCUMENT." ], "SCORE": "PASS" }
PASS
1,973
{ "REASONING": [ "The DOCUMENT states that for influenza virus infections, virus shedding is highest on the day of illness onset and relatively higher from shortly before symptom onset until a few days after onset.", "For 2019-nCoV, the DOCUMENT mentions that transmission patterns appear more similar to influenza, with contagiousness occurring around the time of symptom onset.", "The ANSWER 'a few days after illness onset' is not directly supported by the DOCUMENT, which emphasizes the time around symptom onset rather than specifically a few days after." ], "SCORE": "FAIL" }
FAIL
1,540