Datasets:

surrey-nlp

/

PLOD-filtered

like 0

[ "Because", "tobacco", "use", "is", "a", "key", "risk", "factor", "for", "CVD", "and", "for", "several", "other", "noncommunicable", "diseases", ",", "the", "World", "Health", "Organization", "has", "developed", "an", "international", "instrument", "for", "tobacco", "control", "called", "the", "Framework", "Convention", "on", "Tobacco", "Control", "(", "FCTC", ")", ".", "Parties", "to", "the", "FCTC", "(", "currently", "176", "countries", ")", "agree", "to", "implement", "a", "set", "of", "core", "tobacco", "control", "provisions", "including", "legislation", "to", "ban", "tobacco", "advertising", "and", "to", "increase", "tobacco", "taxes", "." ]

[ 14, 8, 8, 3, 6, 0, 8, 8, 1, 12, 5, 1, 0, 0, 0, 8, 13, 6, 12, 12, 12, 3, 16, 6, 0, 8, 1, 8, 8, 16, 6, 12, 12, 1, 12, 12, 13, 12, 13, 13, 8, 10, 6, 12, 13, 2, 9, 8, 13, 16, 10, 16, 6, 8, 1, 0, 8, 8, 8, 16, 8, 10, 16, 8, 8, 5, 10, 16, 8, 8, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 4, 4, 0, 1, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "Our", "findings", "begin", "to", "validate", "the", "idea", "that", "an", "interphase", "“", "Microtubule", "Integrity", "Response", "”", "(", "MIR", ")", "pathway", "exists", "." ]

[ 11, 8, 16, 10, 16, 6, 8, 14, 6, 0, 13, 12, 12, 12, 13, 13, 12, 13, 8, 16, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 0, 0, 1, 0, 0, 0, 0 ]

[ "Unfortunately", ",", "parents", "in", "rural", "areas", "in", "sub", "-", "Saharan", "Africa", "rarely", "have", "easy", "access", "to", "health", "facilities", "and", "sick", "children", "are", "often", "treated", "at", "home", "by", "community", "health", "workers", "(", "CHWs", ",", "individuals", "with", "some", "medical", "training", "who", "provide", "basic", "health", "care", "to", "their", "communities", ")", ",", "drug", "sellers", ",", "and", "traditional", "healers", "." ]

[ 2, 13, 8, 1, 0, 8, 1, 0, 0, 0, 12, 2, 16, 0, 8, 1, 8, 8, 5, 0, 8, 3, 2, 16, 1, 8, 1, 8, 8, 8, 13, 12, 13, 8, 1, 6, 0, 8, 11, 16, 0, 8, 8, 1, 11, 8, 13, 13, 8, 8, 13, 5, 0, 8, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "Cells", "were", "fixed", "and", "double", "-", "labeled", "with", "fluorescein", "isothiocyanate", "(", "FITC)–Pisum", "sativum", "agglutinin", "(", "PSA)—to", "distinguish", "between", "reacted", "and", "intact", "spermatozoa", "—", "and", "with", "an", "anti", "-", "syntaxin1A", "antibody", "(", "Figure", "5", ")", "." ]

[ 8, 3, 16, 5, 2, 0, 16, 1, 8, 8, 13, 12, 8, 8, 13, 12, 16, 1, 16, 5, 0, 8, 13, 5, 1, 6, 0, 0, 0, 8, 13, 12, 9, 13, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 0, 1, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "De", "novo", "lipogenesis", "is", "driven", "by", "sterol", "regulatory", "-", "element", "binding", "proteins", "(", "SREBPs", ")", ",", "identified", "by", "Brown", "and", "Goldstein", "to", "be", "transcription", "factors", "that", "are", "important", "for", "the", "regulation", "of", "genes", "that", "maintain", "cellular", "lipid", "homeostasis", "." ]

[ 17, 17, 8, 3, 16, 1, 8, 0, 13, 8, 16, 8, 13, 12, 13, 13, 16, 1, 12, 5, 12, 10, 3, 8, 8, 11, 3, 0, 1, 6, 8, 1, 8, 11, 16, 0, 8, 8, 13 ]

[ 0, 0, 0, 0, 0, 0, 3, 4, 4, 4, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "Lifelong", "triple", "-", "drug", "antiretroviral", "therapy", "(", "ART", ")", "for", "all", "women", "living", "with", "HIV", "regardless", "of", "disease", "status", "(", "per", "the", "World", "Health", "Organization", "’s", "Option", "B+", "approach", ")", "has", "emerged", "as", "the", "standard", "for", "reducing", "vertical", "HIV", "transmission", "and", "promoting", "maternal", "health", "[", "3", "]", "." ]

[ 0, 0, 13, 0, 0, 8, 13, 12, 13, 1, 6, 8, 16, 1, 12, 2, 1, 8, 8, 13, 1, 6, 12, 12, 12, 10, 8, 8, 8, 13, 3, 16, 1, 6, 8, 1, 16, 0, 12, 8, 5, 16, 0, 8, 13, 9, 13, 13 ]

[ 0, 0, 0, 0, 3, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "In", "addition", ",", "a", "noticeable", "increase", "was", "observed", "in", "lactate", "dehydrogenase", "(", "LDH", ")", "for", "28", "patients", "(", "among", "34", "patients", ";", "82", "%", ")", "and", "in", "α", "-", "hydroxybutyrate", "dehydrogenase", "(", "α", ")", "for", "25", "patients", "(", "among", "34", "patients", ";", "74", "%", ")", "." ]

[ 1, 8, 13, 6, 0, 8, 3, 16, 1, 8, 8, 13, 12, 13, 1, 9, 8, 13, 1, 9, 8, 13, 9, 13, 13, 5, 1, 13, 8, 8, 8, 13, 12, 13, 1, 9, 8, 13, 1, 9, 8, 13, 9, 13, 13, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "Among", "a", "growing", "number", "of", "CN", "measurement", "tools", "for", "adults", ",", "two", "are", "commonly", "used", ":", "the", "Nature", "Relatedness", "Scale", "(", "NRS", ")", "[", "36", "]", "and", "the", "Connectedness", "to", "Nature", "Scale", "(", "CNS", ")", "[", "7", "]", "." ]

[ 1, 6, 16, 8, 1, 12, 8, 8, 1, 8, 13, 9, 3, 2, 16, 13, 6, 12, 12, 12, 13, 12, 13, 13, 9, 13, 5, 6, 12, 1, 12, 12, 13, 12, 13, 13, 9, 13, 13 ]

[ 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 3, 4, 4, 4, 0, 1, 0, 0, 0, 0, 0 ]

[ "Scale", "bars", "0.5", "mm", "(", "A", ",", "B", ",", "G", "and", "H", ")", ",", "50", "μm", "(", "C", "-", "F", ")", ",", "and", "50", "μm", "(", "I", "-", "L", ")", ".", "CMI1", ",", "Ca2", "+", "-dependent", "modulator", "of", "ICR1", "ICR1", ";", "Col-0", ",", "Arabidopsis", "Columbia-0", ";", "GFP", ",", "green", "fluorescent", "protein", ";", "ICR1", ",", "interactor", "of", "constitutively", "active", "ROP", "ROP", ";", "mRFP", ",", "monomeric", "red", "fluorescent", "protein", ";", "QC", ",", "quiescent", "center", ";", "WT", ",", "wild", "type", "." ]

[ 8, 8, 9, 8, 13, 8, 13, 8, 13, 5, 5, 8, 13, 13, 9, 8, 13, 8, 13, 8, 13, 13, 5, 9, 8, 13, 8, 13, 8, 13, 13, 12, 13, 8, 8, 0, 8, 1, 12, 12, 13, 8, 13, 12, 12, 13, 12, 13, 0, 0, 8, 13, 12, 13, 8, 1, 2, 0, 8, 12, 13, 12, 13, 0, 0, 0, 8, 13, 12, 13, 0, 8, 13, 12, 13, 0, 8, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 3, 4, 4, 4, 4, 4, 1, 0, 0, 0, 0, 0, 0, 1, 0, 3, 4, 4, 0, 1, 0, 3, 4, 4, 4, 4, 1, 0, 1, 0, 3, 4, 4, 4, 0, 1, 0, 3, 4, 0, 1, 0, 3, 4, 0 ]

[ "Dux", ",", "double", "homeobox", ";", "GFP", ",", "green", "fluorescent", "protein", ";", "MERVL", ",", "murine", "endogenous", "retrovirus", "-", "L", ";", "Pias4", ",", "protein", "inhibitor", "of", "activated", "STAT", "4", ";", "RNA", ",", "RNA", "sequencing", ";", "-seqRT", "-qPCR", ",", "quantitative", "reverse", "transcription", "PCR", ";", "Zscan4d", ",", "zinc", "figure", "and", "SCAN", "domain", "containing", "4D." ]

[ 12, 13, 0, 8, 13, 12, 13, 0, 0, 8, 13, 12, 13, 0, 0, 8, 13, 8, 13, 12, 13, 8, 8, 1, 16, 12, 9, 13, 12, 13, 8, 8, 13, 12, 12, 13, 0, 0, 8, 8, 13, 12, 13, 8, 8, 5, 8, 8, 16, 8 ]

[ 1, 0, 3, 4, 0, 1, 0, 3, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 3, 4, 0, 1, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "CNS", ",", "central", "nervous", "system", ";", "FWS", ",", "fever", "without", "source", ";", "NA", ",", "not", "applicable", "." ]

[ 12, 13, 0, 0, 8, 13, 12, 13, 8, 1, 8, 13, 12, 13, 10, 0, 13 ]

[ 1, 0, 3, 4, 4, 0, 1, 0, 3, 4, 4, 0, 0, 0, 0, 0, 0 ]

[ "adjusted", "aHR", "Hazard", "Ratio", ",", "Cox", "CPH", "Proportional", "Hazard", "FSPR", "Flexible", "Parametric", "Survival", "Regression" ]

[ 16, 12, 8, 8, 13, 12, 12, 12, 8, 12, 0, 0, 8, 8 ]

[ 3, 1, 4, 4, 0, 3, 1, 4, 4, 0, 0, 0, 0, 0 ]

[ "Data", "are", "expressed", "as", "the", "mean", "±", "SD", "of", "two", "independent", "experiments", "(", "arbitrary", "units", ",", "AU", ")", ".", "Statistical", "analysis", ":", "ANOVA", "+", "Tukey", "’s", "post", "-", "test", "." ]

[ 8, 3, 16, 1, 6, 8, 15, 8, 1, 9, 0, 8, 13, 0, 8, 13, 12, 13, 13, 0, 8, 13, 12, 5, 12, 10, 8, 8, 8, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "The", "energy", "cost", "of", "running", "(", "Erun", ")", "is", "one", "of", "the", "key", "determinants", "of", "distance", "running", "performance", "[", "1", "]", "." ]

[ 6, 8, 8, 1, 8, 13, 12, 13, 3, 9, 1, 6, 0, 8, 1, 8, 8, 8, 13, 9, 13, 13 ]

[ 0, 3, 4, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "For", "several", "steps", "in", "the", "work", ",", "amino", "acid", "analysis", "(", "AAA", ")", "was", "used", "to", "determine", "the", "concentration", "of", "both", "enzyme", "and", "substrate", "in", "addition", "to", "monitoring", "the", "lysine", "-", "to", "-", "dimethyllysine", "conversion[23", "]", "." ]

[ 1, 0, 8, 1, 6, 8, 13, 8, 8, 8, 13, 12, 13, 3, 16, 1, 16, 6, 8, 1, 5, 8, 5, 8, 1, 8, 1, 16, 6, 8, 13, 1, 13, 8, 8, 13, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "Odds", "ratios", "(", "ORs", ")", "and", "their", "95", "%", "confidence", "intervals", "(", "CIs", ")", "of", "pancreatic", "cancer", "for", "higher", "tertiles", "of", "the", "biomarkers", "relative", "to", "the", "lowest", "tertile", "were", "calculated", "using", "conditional", "logistic", "regression", "[", "27", "]", "." ]

[ 8, 8, 13, 12, 13, 5, 11, 9, 8, 8, 8, 13, 12, 13, 1, 0, 8, 1, 0, 8, 1, 6, 8, 0, 1, 6, 0, 8, 3, 16, 16, 0, 0, 8, 13, 9, 13, 13 ]

[ 3, 4, 0, 1, 0, 0, 0, 0, 0, 3, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "We", "conducted", "a", "systematic", "review", "and", "meta", "-", "analysis", "after", "registration", "of", "the", "protocol", "in", "PROSPERO", "(", "CRD42019135116", ")", "following", "the", "MOOSE", "(", "Meta", "-", "Analysis", "of", "Observational", "Studies", "in", "Epidemiology", ")", "." ]

[ 11, 16, 6, 0, 8, 5, 8, 12, 8, 1, 8, 1, 6, 8, 1, 12, 13, 12, 13, 16, 6, 12, 13, 12, 12, 12, 1, 12, 12, 1, 12, 13, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 3, 4, 4, 4, 4, 4, 4, 4, 0, 0 ]

[ "The", "samples", "were", "analyzed", "using", "HPLC", "and", "high", "-", "performance", "liquid", "chromatography", "–", "electrospray", "ionization", "–", "tandem", "mass", "spectrometry", "(", "LC", "-", "ESI", "-", "MS", "/", "MS", ")", "." ]

[ 6, 8, 3, 16, 16, 12, 5, 0, 13, 8, 8, 8, 13, 8, 8, 13, 8, 8, 8, 13, 12, 13, 12, 13, 12, 15, 12, 13, 13 ]

[ 0, 0, 0, 0, 0, 1, 0, 3, 4, 4, 4, 4, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "NICU", ",", "neonatal", "intensive", "care", "unit" ]

[ 12, 13, 0, 0, 8, 8 ]

[ 1, 0, 3, 4, 4, 4 ]

[ "Significant", "chromatin", "immunoprecipitation", "(", "ChIP", ")", "enrichment", "of", "MITF", "was", "observed", "at", "the", "promoter", "regions", "of", "all", "three", "of", "the", "ISGs", "predicted", "to", "be", "MITF", "targets", "(", "Ifih1", ",", "Ifit3", ",", "and", "Stat1", ")", "as", "well", "as", "at", "the", "promoter", "region", "of", "a", "known", "MITF", "target", "gene", ",", "Dct", "(", "Fig", "4D", ")", ".", "No", "MITF", "enrichment", "was", "observed", "for", "the", "negative", "control", "region", ",", "a", "sequence", "within", "the", "centromere", "." ]

[ 0, 8, 8, 13, 12, 13, 8, 1, 12, 3, 16, 1, 6, 8, 8, 1, 6, 9, 1, 6, 12, 16, 10, 3, 12, 8, 13, 12, 13, 12, 13, 5, 8, 13, 1, 2, 1, 1, 6, 8, 8, 1, 6, 16, 12, 8, 8, 13, 12, 13, 12, 9, 13, 13, 6, 12, 8, 3, 16, 1, 6, 0, 8, 8, 13, 6, 8, 1, 6, 8, 13 ]

[ 0, 3, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "As", "the", "histological", "images", "contain", "multiple", "tiles", ",", "we", "also", "constructed", "a", "tissue", "classifier", "for", "whole", "slide", "images", "(", "WSI", ")", "by", "applying", "the", "tile", "classifier", "on", "all", "tiles", "of", "the", "given", "WSI", "and", "aggregating", "the", "corresponding", "predictions", "using", "the", "majority", "vote", "." ]

[ 14, 6, 0, 8, 16, 0, 8, 13, 11, 2, 16, 6, 8, 8, 1, 0, 8, 8, 13, 12, 13, 1, 16, 6, 8, 8, 1, 6, 8, 1, 6, 16, 12, 5, 16, 6, 0, 8, 16, 6, 8, 8, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "Nestin(+", ")", "cells", "in", "dorsal", "regions", "of", "the", "subventricular", "layer", "(", "SVL", ")", "of", "the", "lateral", "ventricle", "showed", "similar", "activity", "to", "dmNes+RG", "cells", "(", "S7C", "–", "S7", "G", "Fig", ")", "." ]

[ 12, 13, 8, 1, 0, 8, 1, 6, 0, 8, 13, 12, 13, 1, 6, 0, 8, 16, 0, 8, 1, 12, 8, 13, 12, 13, 12, 12, 12, 13, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "BAC", ",", "bacterial", "artificial", "chromosome", ";", "C", ",", "clockwise", ";", "CC", ",", "counterclockwise", ";", "NP", ",", "no", "preference", ";", "SEM", ",", "standard", "error", "of", "the", "mean", "." ]

[ 12, 13, 0, 0, 8, 13, 8, 13, 2, 13, 8, 13, 2, 13, 8, 13, 6, 8, 13, 12, 13, 0, 8, 1, 6, 8, 13 ]

[ 1, 0, 3, 4, 4, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 3, 4, 4, 4, 4, 0 ]

[ "Over", "the", "last", "fifteen", "years", ",", "funding", "for", "malaria", "control", "activities", "has", "increased", "dramatically", "across", "Africa", ",", "leading", "to", "the", "scale", "-", "up", "of", "proven", "interventions", "including", "distribution", "of", "long", "-", "lasting", "insecticidal", "nets", "(", "LLINs", ")", ",", "indoor", "residual", "spraying", "of", "insecticide", "(", "IRS", ")", ",", "and", "treatment", "of", "malaria", "cases", "with", "artemisinin", "-", "based", "combination", "therapy", "(", "ACT", ")", "[", "1", "]", "." ]

[ 1, 6, 0, 9, 8, 13, 8, 1, 8, 8, 8, 3, 16, 2, 1, 12, 13, 16, 1, 6, 8, 13, 8, 1, 16, 8, 16, 8, 1, 2, 13, 16, 0, 8, 13, 12, 13, 13, 0, 0, 8, 1, 8, 13, 12, 13, 13, 5, 8, 1, 8, 8, 1, 8, 13, 16, 8, 8, 13, 12, 13, 13, 9, 13, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 4, 4, 0, 1, 0, 0, 3, 4, 4, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 4, 4, 0, 1, 0, 0, 0, 0, 0 ]

[ "One", "study", "found", "that", "the", "frequency", "of", "tyrosine", "kinases", "(", "TKs", ")", "in", "the", "proteome", "correlates", "negatively", "with", "the", "frequency", "of", "tyrosine", "residues", "in", "the", "proteome", ",", "implying", "some", "extent", "of", "coevolution", "between", "kinases", "and", "substrates", "[", "15", "]", "." ]

[ 9, 8, 16, 14, 6, 8, 1, 8, 8, 13, 12, 13, 1, 6, 8, 16, 2, 1, 6, 8, 1, 8, 8, 1, 6, 8, 13, 16, 6, 8, 1, 8, 1, 8, 5, 8, 13, 9, 13, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 3, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "The", "researchers", "assessed", "the", "quality", "of", "each", "selected", "study", "and", "included", "only", "those", "studies", "that", "used", "validated", "diagnostic", "instruments", "and", "screening", "tools", "to", "assess", "mental", "health", "disorders", "in", "their", "calculations", "of", "the", "pooled", "(", "combined", ")", "odds", "ratio", "(", "OR", ")", "through", "meta", "-", "analysis", "." ]

[ 6, 8, 16, 6, 8, 1, 6, 16, 8, 5, 16, 2, 6, 8, 11, 16, 16, 0, 8, 5, 8, 8, 10, 16, 0, 8, 8, 1, 11, 8, 1, 6, 16, 13, 0, 13, 8, 8, 13, 12, 13, 1, 8, 8, 8, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 0, 1, 0, 0, 0, 0, 0, 0 ]

[ "Aerobic", "ExCap", "is", "determined", "by", "maximal", "oxygen", "uptake", "(", "VO2max", ")", ",", "which", "is", "a", "function", "of", "oxygen", "delivery", "and", "oxygen", "utilization", "[", "9", "]", "." ]

[ 0, 12, 3, 16, 1, 0, 8, 8, 13, 12, 13, 13, 11, 3, 6, 8, 1, 8, 8, 5, 8, 8, 13, 9, 13, 13 ]

[ 0, 1, 0, 0, 0, 3, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "The", "intracluster", "correlation", "coefficient", "(", "ICC", ")", "was", "unknown", ",", "but", "we", "assumed", "that", "a", "power", "of", "90", "%", "at", "independency", "(", "i.e.", ",", "no", "correlation", "between", "clusters", ",", "ICC", "of", "0", ")", "would", "result", "in", "a", "power", "of", "80", "%", "or", "more", "in", "multilevel", "analysis", "." ]

[ 6, 0, 8, 8, 13, 12, 13, 3, 0, 13, 5, 11, 16, 14, 6, 8, 1, 9, 8, 1, 8, 13, 17, 13, 6, 8, 1, 8, 13, 12, 1, 9, 13, 3, 16, 1, 6, 8, 1, 9, 8, 5, 0, 1, 0, 8, 13 ]

[ 0, 3, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "The", "growing", "availability", "of", "comprehensive", "clinical", "datasets", ",", "such", "as", "linked", "electronic", "health", "records", "(", "EHRs", ")", "with", "rich", "information", "from", "millions", "of", "individuals", ",", "together", "with", "advances", "in", "machine", "learning", "offer", "new", "opportunities", "for", "development", "of", "novel", "risk", "prediction", "models", "that", "are", "better", "at", "predicting", "risk", "." ]

[ 6, 16, 8, 1, 0, 0, 8, 13, 0, 1, 16, 0, 8, 8, 13, 12, 13, 1, 0, 8, 1, 8, 1, 8, 13, 2, 1, 8, 1, 8, 8, 16, 0, 8, 1, 8, 1, 0, 8, 8, 8, 11, 3, 0, 1, 16, 8, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "These", "authors", "thus", "estimated", "the", "potential", "gains", "in", "life", "expectancy", "(", "PGLE", ")", "under", "the", "Chinese", "Ambient", "Air", "Quality", "Standards", "and", "WHO", "'s", "air", "quality", "guidelines", "." ]

[ 6, 8, 2, 16, 6, 0, 8, 1, 8, 8, 13, 12, 13, 1, 6, 12, 12, 12, 12, 12, 5, 12, 10, 8, 8, 8, 13 ]

[ 0, 0, 0, 0, 0, 3, 4, 4, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0 ]

[ "The", "method", "how", "enhancer", "RNAs", "(", "eRNA", ")", "were", "analyzed", ",", "was", "previously", "described", "by", "Brown", "et", "al", ".", "[", "21", "]", "." ]

[ 6, 8, 14, 8, 8, 13, 12, 13, 3, 16, 13, 3, 2, 16, 1, 12, 12, 8, 13, 13, 9, 13, 13 ]

[ 0, 0, 0, 3, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "Genetic", "and", "molecular", "studies", "in", "Drosophila", "indicate", "Disheveled", "(", "Dsh", ")", ",", "a", "cytoplasmic", "transducer", "of", "Wnt", "signaling", ";", "Frizzled", "(", "Fz", ")", ",", "a", "seven", "-", "transmembrane", "receptor", "for", "Wnt", "ligands", ";", "and", "Van", "Gogh", "(", "Vang", ")", ",", "a", "four", "-", "pass", "transmembrane", "protein", ",", "as", "core", "Wnt", "-", "PCP", "proteins", "." ]

[ 0, 5, 0, 8, 1, 12, 16, 12, 13, 12, 13, 13, 6, 8, 8, 1, 12, 8, 13, 12, 13, 12, 13, 13, 6, 9, 13, 8, 8, 1, 12, 8, 13, 5, 12, 12, 13, 12, 13, 13, 6, 9, 13, 8, 8, 8, 13, 1, 8, 12, 13, 12, 8, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0 ]

[ "We", "also", "thank", "Adam", "Hanina", "and", "Laura", "Shafner", "of", "AiCure", "(", "New", "York", ",", "NY", ")", "for", "helpful", "comments", "on", "an", "earlier", "version", "of", "our", "cost", "-", "effectiveness", "study", "." ]

[ 11, 2, 16, 12, 12, 5, 12, 12, 1, 12, 13, 12, 12, 13, 12, 13, 1, 0, 8, 1, 6, 0, 8, 1, 11, 8, 13, 8, 8, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "We", "assumed", "there", "would", "be", "25", "ASHAs", "associated", "with", "one", "PHC", ".", "We", "assumed", "intraclass", "correlation", "(", "ICC", ")", "to", "be", "0.02", "in", "light", "of", "no", "existing", "information", "available", "regarding", "ICC", ".", "We", "estimated", "that", "there", "might", "be", "loss", "of", "one", "cluster", "per", "arm", "and", "three", "ASHAs", "per", "PHC", "over", "the", "course", "of", "the", "study", "period", "." ]

[ 11, 16, 11, 3, 3, 9, 12, 16, 1, 9, 12, 13, 11, 16, 8, 8, 13, 12, 13, 10, 3, 9, 1, 8, 1, 6, 16, 8, 0, 16, 12, 13, 11, 16, 14, 11, 3, 3, 8, 1, 9, 8, 1, 8, 5, 9, 12, 1, 12, 1, 6, 8, 1, 6, 8, 8, 13 ]

[ 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 1, 0, 0, 0, 3, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "This", "C", "-", "terminal", "extracellular", "domain", "exhibits", "dipeptidyl", "peptidase", "IV", "(", "DPPIV", ")", "activity", "." ]

[ 6, 8, 0, 0, 0, 8, 16, 8, 8, 9, 13, 12, 13, 8, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 0, 1, 0, 0, 0 ]

[ "The", "Development", "of", "AntiRetroviral", "Therapy", "in", "Africa", "(", "DART", ")", "trial", "was", "designed", "to", "investigate", "the", "impact", "of", "routine", "laboratory", "monitoring", "for", "ART", "toxicity", "(", "haematology", "/", "biochemistry", ")", "and", "efficacy", "(", "CD4", "counts", ")", "on", "long", "-", "term", "clinical", "outcomes", "compared", "to", "clinically", "driven", "monitoring", "(", "toxicity", "tests", "only", "if", "clinically", "indicated", "and", "no", "CD4", "counts", ")", "[", "14", "]", ".", "65", "%", "of", "trial", "participants", "were", "women", ",", "and", "three", "different", "initial", "ART", "regimens", "were", "used", "to", "increase", "generalisability", "." ]

[ 6, 12, 1, 12, 12, 1, 12, 13, 12, 13, 8, 3, 16, 10, 16, 6, 8, 1, 0, 8, 8, 1, 12, 8, 13, 8, 15, 8, 13, 5, 8, 13, 8, 8, 13, 1, 0, 13, 8, 0, 8, 16, 10, 2, 16, 8, 13, 8, 8, 2, 14, 2, 16, 5, 6, 8, 8, 13, 13, 17, 13, 13, 9, 8, 1, 8, 8, 3, 8, 13, 5, 9, 0, 0, 12, 8, 3, 16, 10, 16, 8, 13 ]

[ 0, 3, 4, 3, 4, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0 ]

[ "Calreticulin", "(", "CRT", ")", "is", "a", "high", "-", "capacity", "Ca2", "+", "protein", "whose", "expression", "is", "up", "-", "regulated", "during", "cellular", "transformation", "and", "is", "associated", "with", "disease", "progression", "in", "multiple", "types", "of", "malignancies", "." ]

[ 8, 13, 12, 13, 3, 6, 0, 13, 8, 8, 8, 8, 6, 8, 3, 2, 13, 16, 1, 0, 8, 5, 3, 16, 1, 8, 8, 1, 0, 8, 1, 8, 13 ]

[ 3, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "The", "BMI", "was", "categorized", "following", "the", "World", "Health", "Organization", "(", "WHO", ")", "Asia", "-", "Pacific", "classification", "as", "normal", "(", "BMI", "<", "25.0", "kg", "/", "m2", ")", "and", "obese", "(", "BMI", "≥25", "kg", "/", "m2", ")", "[", "16", "]", "." ]

[ 6, 12, 3, 16, 16, 6, 12, 12, 12, 13, 12, 13, 12, 13, 12, 8, 1, 0, 13, 12, 1, 9, 8, 15, 8, 13, 5, 0, 13, 12, 9, 8, 15, 8, 13, 13, 9, 13, 13 ]

[ 0, 1, 0, 0, 0, 0, 3, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "Specifically", ",", "a", "block", "of", "size", "3", "was", "used", ";", "within", "each", "block", ",", "2", "participants", "were", "randomized", "to", "WOT", ",", "and", "1", "participant", "was", "randomized", "to", "DOT", ".", "Subjects", "were", "recruited", "from", "SD", "and", "OC", "Divisions", "of", "TB", "Control", "and", "Refugee", "Health", ",", "which", "were", "both", "study", "sites", ",", "in", "addition", "to", "the", "Anti", "-", "Viral", "Research", "Center", "(", "AVRC", ")", "at", "University", "of", "California", "SD", "(", "UCSD", ")", ".", "The", "protocol", "(", "“", "AHF", "TB", "001", "Wirelessly", "Observed", "Therapy", "in", "Comparison", "to", "Directly", "Observed", "Therapy", "for", "the", "Treatment", "of", "Tuberculosis", "”", ";", "ClinicalTrials.gov", "NCT01960257", ")", "was", "approved", "by", "the", "UCSD", "Internal", "Review", "Board", "(", "#", "130841", ")", ",", "the", "County", "of", "Orange", "Health", "Care", "Agency", "Human", "Subjects", "Review", "Committee", "(", "#", "2014–06", ")", ",", "and", "the", "County", "of", "SD", "Health", "and", "Human", "Services", "Agency", "(", "#", "121274X", ")", "and", "was", "conducted", "in", "accordance", "with", "the", "principles", "of", "good", "clinical", "practice", "." ]

[ 2, 13, 6, 8, 1, 8, 9, 3, 16, 13, 1, 6, 8, 13, 9, 8, 3, 16, 1, 12, 13, 5, 9, 8, 3, 16, 1, 12, 13, 12, 3, 16, 1, 12, 5, 12, 12, 1, 12, 12, 5, 12, 12, 13, 11, 3, 6, 8, 8, 13, 1, 8, 1, 6, 12, 12, 12, 12, 12, 13, 12, 13, 1, 12, 1, 12, 12, 13, 12, 13, 13, 6, 8, 13, 13, 12, 12, 9, 2, 16, 8, 1, 8, 1, 2, 16, 8, 1, 6, 8, 1, 8, 13, 13, 17, 9, 13, 3, 16, 1, 6, 12, 12, 12, 12, 13, 13, 9, 13, 13, 6, 12, 1, 12, 12, 12, 12, 12, 12, 12, 12, 13, 13, 9, 13, 13, 5, 6, 12, 1, 12, 12, 5, 12, 12, 12, 13, 13, 9, 13, 5, 3, 16, 1, 8, 1, 6, 8, 1, 0, 0, 8, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 1, 0, 1, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 4, 4, 0, 1, 0, 0, 0, 0, 0, 1, 0, 1, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 0, 0, 0, 0, 3, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "Of", "these", ",", "16,766", "were", "associated", "with", "Gene", "Ontology", "terms", "(", "GO", "terms", ";", "08/04/12", "GO", "database", ")", "." ]

[ 1, 11, 13, 9, 3, 16, 1, 12, 12, 8, 13, 12, 8, 13, 9, 12, 8, 13, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 3, 4, 0, 0, 1, 0, 0, 0, 1, 0, 0, 0 ]

[ "GWAS", ",", "genome", "-", "wide", "association", "study", "." ]

[ 12, 13, 8, 13, 0, 8, 8, 13 ]

[ 1, 0, 3, 4, 4, 4, 4, 0 ]

[ "MCR", ",", "metabolic", "-", "chronotropic", "relationship", "." ]

[ 12, 13, 0, 13, 0, 8, 13 ]

[ 1, 0, 3, 4, 4, 4, 0 ]

[ "(", "A", ")", "Deaths", ".", "(", "B", ")", "DALYs", ".", "DALY", ",", "disability", "-", "adjusted", "life", "year", "." ]

[ 13, 17, 13, 8, 13, 13, 17, 13, 12, 13, 12, 13, 8, 13, 16, 8, 8, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 1, 0, 3, 4, 4, 4, 4, 0 ]

[ "Although", "we", "performed", "a", "threshold", "test", "to", "determine", "each", "participant", "'s", "just", "noticeable", "difference", "(", "JND", ")", "thresholds", "for", "each", "stimulus", "type", ",", "it", "is", "possible", "that", "these", "estimates", "erred", "on", "the", "side", "of", "being", "too", "easy", "for", "the", "auditory", "stimuli", ",", "despite", "the", "fact", "that", "JNDs", "were", "estimated", "using", "the", "same", "algorithm", "for", "all", "stimulus", "types", "." ]

[ 14, 11, 16, 6, 8, 8, 10, 16, 6, 8, 10, 2, 0, 8, 13, 12, 13, 8, 1, 6, 8, 8, 13, 11, 3, 0, 14, 6, 8, 16, 1, 6, 8, 1, 3, 2, 0, 1, 6, 0, 8, 13, 14, 6, 8, 14, 12, 3, 16, 16, 6, 0, 8, 1, 6, 8, 8, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "Bioresorbable", "scaffolds", ",", "developed", "to", "overcome", "some", "of", "the", "(", "late", ")", "adverse", "events", "of", "metallic", "drug", "-", "eluting", "stents", "(", "DES", ")", ",", "are", "the", "latest", "innovation", "in", "the", "treatment", "of", "coronary", "artery", "disease", "." ]

[ 0, 8, 13, 16, 10, 16, 11, 1, 6, 13, 0, 13, 0, 8, 1, 0, 8, 13, 16, 8, 13, 12, 13, 13, 3, 6, 0, 8, 1, 6, 8, 1, 0, 8, 8, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "Intimate", "partner", "violence", "(", "IPV", ")", "is", "associated", "with", "increased", "HIV", "risk", "and", "other", "adverse", "health", "and", "psychosocial", "outcomes", "." ]

[ 0, 8, 8, 13, 12, 13, 3, 16, 1, 16, 12, 8, 5, 0, 0, 8, 5, 0, 8, 13 ]

[ 3, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "It", "has", "been", "extensively", "described", "that", "p38MAPK", "triggers", "browning", "and", "BAT", "activation", "through", "the", "transcription", "of", "uncoupling", "protein", "1", "(", "UCP1", ")", "via", "cAMP", "response", "element", "-", "binding", "(", "CREB", ")", ",", "activating", "transcription", "factor", "2", "(", "ATF2", ")", ",", "and", "peroxisome", "proliferator", "-", "activated", "receptor", "gamma", "coactivator", "1α", "(", "PGC1α", ")", "activation", "." ]

[ 11, 3, 3, 2, 16, 14, 8, 16, 8, 5, 12, 8, 1, 6, 8, 1, 16, 8, 9, 13, 12, 13, 1, 8, 8, 8, 13, 8, 13, 12, 13, 13, 16, 8, 8, 9, 13, 12, 13, 13, 5, 8, 8, 13, 16, 8, 8, 8, 9, 13, 12, 13, 8, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 3, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 4, 0, 1, 0, 0, 0, 0, 3, 4, 4, 4, 4, 4, 4, 0, 1, 0, 0, 0 ]

[ "Fully", "adjusted", "is", "adjusted", "for", "Index", "of", "Multiple", "Deprivation", "(", "IMD", ")", ",", "birthweight", ",", "maternal", "age", ",", "sex", ",", "and", "multiple", "birth", "." ]

[ 2, 16, 3, 16, 1, 12, 1, 12, 8, 13, 12, 13, 13, 8, 13, 0, 8, 13, 8, 13, 5, 0, 8, 13 ]

[ 0, 0, 0, 0, 0, 3, 4, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "Unexpectedly", ",", "we", "found", "that", "Notch1", "-", "expressing", "cells", "invariably", "lacked", "the", "expression", "of", "ERα", "and", "PR", "(", "Fig", ".", "2F", ",", "G", ")", ",", "and", "we", "confirmed", "these", "results", "by", "quantitative", "Real", "Time", "Polymerase", "Chain", "Reaction", "(", "qRT", ")", "in", "sorted", "-PCRGFP", "-", "labeled", "cells", "(", "S3B", ",", "C", "Fig", ".", ")", "." ]

[ 2, 13, 11, 16, 14, 8, 13, 16, 8, 2, 16, 6, 8, 1, 12, 5, 12, 13, 12, 13, 9, 13, 8, 13, 13, 5, 11, 16, 6, 8, 1, 0, 0, 8, 12, 12, 12, 13, 12, 13, 1, 0, 12, 13, 16, 8, 13, 12, 13, 12, 12, 13, 13, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 4, 4, 4, 0, 1, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "GGOH", ",", "geranylgeraniol", ";", "IDC", ",", "intraerythrocytic", "developmental", "cycle", ";", "ns", ",", "not", "significant", "." ]

[ 12, 13, 8, 13, 12, 13, 0, 0, 8, 13, 8, 13, 10, 0, 13 ]

[ 1, 0, 3, 0, 1, 0, 3, 4, 4, 0, 0, 0, 0, 0, 0 ]

[ "Patients", "were", "excluded", "if", "they", "(", "1", ")", "were", "under", "19", "years", "old", ",", "(", "2", ")", "had", "died", ",", "were", "discharged", ",", "or", "were", "transferred", "to", "other", "medical", "institutions", "within", "3", "days", "of", "PICC", "placement", ",", "or", "(", "3", ")", "had", "at", "least", "one", "test", "result", "for", "absolute", "neutrophil", "count", "(", "ANC", ")", "under", "500", "cells", "/", "μL", "during", "catheterization", "." ]

[ 8, 3, 16, 14, 11, 13, 17, 13, 3, 1, 9, 8, 0, 13, 13, 17, 13, 16, 16, 13, 3, 16, 13, 5, 3, 16, 1, 0, 0, 8, 1, 17, 8, 1, 12, 8, 13, 5, 13, 17, 13, 16, 2, 2, 9, 8, 8, 1, 0, 8, 8, 13, 12, 13, 1, 9, 8, 15, 8, 1, 8, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "Little", "is", "known", "about", "the", "mechanism", "of", "action", "of", "Y-320", ",", "other", "than", "it", "inhibited", "IL-17", "production", "by", "murine", "CD4", "T", "cells", "stimulated", "with", "a", "cocktail", "of", "IL-15", ",", "CXCL12", ",", "and", "anti", "-", "CD3", "monoclonal", "antibody", "(", "mAb", ")", "[", "20", "]", "." ]

[ 0, 3, 16, 1, 6, 8, 1, 8, 1, 8, 13, 0, 14, 11, 16, 8, 8, 1, 0, 8, 8, 8, 16, 1, 6, 8, 1, 8, 13, 12, 13, 5, 0, 0, 0, 0, 8, 13, 12, 13, 13, 9, 13, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 0, 1, 0, 0, 0, 0, 0 ]

[ "The", "flow", "under", "consideration", "can", "be", "put", "into", "the", "following", "arrangement", "[", "34", "]", ":", "∂u∂x+∂v∂y=0,(1", ")", "(", "∂u∂t+u∂u∂x+v∂u∂y+2Ω1−γtw)=−1ρnf∂p∂x+νnf(∂2u∂x2+∂2u∂y2)+πj0M0Exp(−πby)8ρnf,(2", ")", "(", "∂v∂t+u∂v∂x+v∂v∂y)=−1ρnf∂p∂y+νnf(∂2v∂x2+∂2v∂y2),(3", ")", "(", "∂w∂t+u∂w∂x+v∂w∂y−2Ω1−γtu)=−1ρnf∂p∂x+νnf(∂2w∂x2+∂2w∂y2)+πj0M0Exp(−πby)8ρnf,(4", ")", "(", "∂T∂t+u∂T∂x+v∂T∂y)=αnf(∂2T∂x2+∂2T∂y2)+μnf(ρcp)nf(4(∂u∂x)2+(∂v∂x+∂u∂y)2)+Q0(T−Tm)(ρcp)nf,(5", ")", "u", "=", "Uw", "=", "ax1−γt", ",", "v=0,w=0,T", "=", "Tmaty=0,u=0,v", "=", "vh", "=", "dhdt=−γ2υfa(1−γt),w=0,T", "=", "Thaty", "=", "h(t).}(6", ")", "Here", "u", ",", "v", "and", "w", "represent", "the", "velocity", "components", "in", "the", "x", ",", "y", "and", "z", "directions", "respectively", ",", "ρnf", "represents", "nanofluid", "density", ",", "νnf=(μnfρnf", ")", "nanofluid", "kinematic", "viscosity", ",", "μnf", "dynamic", "viscosity", ",", "j0(A", "/", "m2", ")", "applied", "current", "density", "in", "the", "electrodes", ",", "M0(Tesla", ")", "magnetization", "of", "the", "permanent", "magnets", ",", "b", "width", "for", "magnets", "and", "electrodes", ",", "Q0", "heat", "absorption", "/generation", "coefficients", ",", "(", "cp)nf", "effective", "heat", "capacity", "of", "nanoparticles", ",", "thermal", "αnf", "diffusivity", "of", "nanofluid", ",", "T", "and", "T0", "temperature", "of", "fluid", "and", "solid", "surface", "respectively", ",", "a", "and", "γ", "dimensional", "constants", ",", "knf", "the", "thermal", "conductivity", "of", "nanofluid", "and", "Ω", "for", "angluar", "velocity", "." ]

[ 12, 8, 1, 8, 3, 3, 16, 1, 6, 16, 8, 13, 9, 13, 13, 17, 13, 13, 17, 13, 13, 17, 13, 13, 17, 13, 13, 17, 13, 8, 17, 17, 17, 17, 13, 17, 17, 17, 17, 17, 17, 17, 17, 17, 17, 17, 13, 2, 8, 13, 8, 5, 8, 16, 6, 8, 8, 1, 6, 8, 13, 8, 5, 8, 8, 2, 13, 12, 16, 8, 8, 13, 17, 13, 8, 0, 8, 13, 12, 0, 8, 13, 12, 15, 17, 13, 16, 8, 8, 1, 6, 8, 13, 12, 13, 13, 1, 6, 0, 8, 13, 8, 8, 1, 8, 5, 8, 13, 12, 8, 8, 8, 8, 13, 13, 8, 0, 8, 8, 1, 8, 13, 0, 12, 8, 1, 8, 13, 8, 5, 12, 8, 1, 8, 5, 0, 8, 2, 13, 8, 5, 13, 0, 8, 13, 12, 6, 0, 8, 1, 8, 5, 13, 1, 8, 8, 13 ]

[ 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 1, 0, 0, 0, 3, 4, 4, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 1, 4, 4, 4, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 3, 4, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "The", "Reduced", "Folate", "Carrier", "1", "(", "RFC1", ",", "official", "symbol", "SLC19A1", ")", "gene", "is", "located", "on", "chromosome", "21", "and", "encodes", "for", "an", "ubiquitously", "expressed", "transmembrane", "protein", "that", "serves", "as", "a", "bi", "-", "directional", "transporter", "of", "reduced", "folate", "species", "such", "as", "5", "-", "methyl", "THF", ",", "the", "main", "circulating", "active", "form", "of", "folate", "[", "32", ",", "33", "]", "and", "it", "is", "involved", "in", "both", "methylation", "pathway", "and", "nucleotides", "synthesis", "." ]

[ 6, 12, 12, 12, 9, 13, 12, 13, 0, 8, 8, 13, 8, 3, 16, 1, 8, 9, 5, 16, 1, 6, 2, 16, 8, 8, 11, 16, 1, 6, 0, 13, 0, 8, 1, 16, 8, 8, 0, 1, 9, 13, 8, 12, 13, 6, 0, 16, 0, 8, 1, 8, 17, 9, 13, 9, 17, 5, 11, 3, 16, 1, 5, 8, 8, 5, 8, 8, 13 ]

[ 0, 3, 4, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "Indeed", ",", "preceding", "visual", "stimuli", "are", "reported", "to", "modulate", "visual", "perception", "after", "brief", "stimulus", "-", "onset", "asynchrony", "(", "SOA", ")", "[", "19–22", "]", "." ]

[ 2, 13, 16, 0, 8, 3, 16, 10, 16, 0, 8, 1, 0, 8, 13, 8, 8, 13, 12, 13, 13, 9, 13, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 4, 0, 1, 0, 0, 0, 0, 0 ]

[ "To", "measure", "ectopic", "cell", "division", ",", "mice", "were", "pulse", "-", "labelled", "with", "bromodeoxyuridine", "(", "BrdU", ")", "2", "h", "before", "sacrifice", "and", "the", "peripheral", "retina", "analyzed", "for", "BrdU", "incorporation", "by", "immunofluorescence", "." ]

[ 10, 16, 0, 8, 8, 13, 8, 3, 8, 13, 16, 1, 8, 13, 12, 13, 9, 8, 1, 8, 5, 6, 0, 8, 16, 1, 12, 8, 1, 8, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0 ]

[ "The", "analysis", "of", "auditory", "brainstem", "responses", "revealed", "a", "significant", "increase", "of", "the", "amplitude", "of", "wave", "IV", ",", "without", "detectable", "differences", "in", "the", "ABR", "thresholds", "or", "peak", "latencies", "(", "Fig", "8)", "." ]

[ 6, 8, 1, 0, 8, 8, 16, 6, 0, 8, 1, 6, 8, 1, 8, 9, 13, 1, 0, 8, 1, 6, 12, 8, 5, 8, 8, 13, 9, 9, 13 ]

[ 0, 0, 0, 3, 4, 4, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "Neonates", "delivered", "from", "mothers", "with", "AF", "MR", "3–4", "had", "significantly", "higher", "ABC", "(", "p", "<", "0.001", ")", "and", "I", "(", "p", "<", "0.001", ")", ",", "and", "increased", "incidence", "of", "suspected", "and/or", "confirmed", "sepsis", "(", ":TratioOR", ":", "4.4", "[", "95", "%", "confidence", "interval", "(", "CI", ")", ",", "1.7", "to", "11.6", "]", ",", "p", "=", "0.003", ")", "compared", "to", "neonates", "from", "mothers", "with", "MR", "0", "or", "MR", "1–2", "even", "after", "adjusting", "for", "GA", "at", "birth", "(", "ABC", ":", "p", "=", "0.002", ";", "I", ":", "p", "=", "0.003", ")", "." ]

[ 8, 16, 1, 8, 1, 12, 12, 9, 16, 2, 0, 12, 13, 8, 1, 9, 13, 5, 12, 13, 8, 1, 9, 13, 13, 5, 0, 8, 1, 16, 5, 16, 8, 13, 12, 13, 9, 13, 9, 8, 8, 8, 13, 12, 13, 13, 9, 1, 9, 13, 13, 8, 15, 9, 13, 16, 1, 8, 1, 8, 1, 12, 9, 5, 12, 9, 2, 1, 16, 1, 12, 1, 8, 13, 12, 13, 8, 15, 9, 13, 12, 13, 8, 15, 9, 13, 13 ]

[ 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 3, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 1, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0 ]

[ "Autosomal", "recessive", "cerebellar", "ataxias", "(", "ARCAs", ")", "are", "a", "large", "group", "of", "neurodegenerative", "disorders", "that", "manifest", "mainly", "in", "children", "and", "young", "adults", "." ]

[ 0, 0, 8, 8, 13, 12, 13, 3, 6, 0, 8, 1, 0, 8, 11, 16, 2, 1, 8, 5, 0, 8, 13 ]

[ 3, 4, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "They", "record", "basic", "data", "on", "the", "household", "and", "all", "household", "members", "on", "an", "electronic", "data", "capture", "(", "EDC", ")", "device", ",", "with", "more", "detailed", "data", "(", "e.g.", ",", "on", "HIV", "test", "history", ",", "ART", "status", ",", "and", "uptake", "of", "HIV", "testing", "and", "other", "services", "provided", "by", "CHiPs", ")", "recorded", "for", "adults", "aged", "18", "y", "and", "above", "who", "consent", "to", "receive", "the", "intervention", "." ]

[ 11, 16, 0, 8, 1, 6, 8, 5, 6, 8, 8, 1, 6, 0, 8, 8, 13, 12, 13, 8, 13, 1, 2, 0, 8, 13, 17, 13, 1, 12, 8, 8, 13, 12, 8, 13, 5, 8, 1, 12, 8, 5, 0, 8, 16, 1, 12, 13, 16, 1, 8, 16, 9, 8, 5, 2, 11, 16, 10, 16, 6, 8, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "In", "seeking", "to", "achieve", "this", ",", "from", "1996", "onwards", "BAT", "appears", "to", "have", "relied", "heavily", "on", "the", "European", "Policy", "Centre", "(", "EPC", ")", "[", "62],[98],[100]–[115", "]", ",", "sometimes", "working", "with", "the", "Weinberg", "Group", "[", "116]–[118", "]", ",", "a", "US", "based", "consultancy", "firm", "that", "had", "also", "been", "involved", "in", "Philip", "Morris", "'", "US", "and", "international", "ETS", "campaign", "[", "73],[119]–[125", "]", "." ]

[ 1, 16, 10, 16, 11, 13, 1, 9, 2, 12, 16, 10, 3, 16, 2, 1, 6, 12, 12, 12, 13, 12, 13, 17, 17, 13, 13, 2, 16, 1, 6, 12, 12, 17, 17, 13, 13, 6, 12, 16, 8, 8, 11, 3, 2, 3, 16, 1, 12, 12, 10, 12, 5, 0, 12, 8, 17, 17, 13, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0 ]

[ "Namely", ",", "we", "compared", "the", "STRAIN", "with", "German", "versions", "of", "the", "Adverse", "Childhood", "Experience", "Questionnaire", "(", "ACE", ";", "[", "17", ",", "24", "]", ")", ",", "Childhood", "Trauma", "Questionnaire", "–", "Short", "Form", "(", "CTQ", ";", "[", "16", ",", "25", "]", ")", ",", "Life", "Event", "Checklist", "for", "DSM", "-", "V", "(", "-SFLEC-5", ";", "[", "19", ",", "26", "]", ")", ",", "Perceived", "Stress", "Scale", "(", "PSS", ";", "[", "21", ",", "27", "]", ")", ",", "and", "Trier", "Inventory", "for", "Chronic", "Stress", "(", "TICS", ";", "[", "20", "]", ")", "." ]

[ 2, 13, 11, 16, 6, 12, 1, 0, 8, 1, 6, 12, 12, 12, 12, 13, 12, 13, 13, 9, 13, 9, 13, 13, 13, 12, 12, 12, 13, 12, 12, 13, 12, 13, 13, 9, 13, 9, 13, 13, 13, 12, 12, 12, 1, 12, 13, 12, 13, 12, 13, 13, 9, 13, 9, 13, 13, 13, 12, 12, 12, 13, 12, 13, 13, 9, 13, 9, 13, 13, 13, 5, 12, 12, 1, 12, 12, 13, 12, 13, 13, 9, 13, 13, 13 ]

[ 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 3, 4, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 4, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0 ]

[ "In", "addition", "to", "phenotypic", "rescue", "of", "morphogenesis", ",", "we", "observed", "expression", "of", "pancreatic", "TFs", "hepatocyte", "nuclear", "factor", "1", "-", "beta", "(", "HNF1B", ")", "and", "pancreatic", "and", "duodenal", "homeobox", "1", "(", "PDX1", ")", "(", "arrowheads", ",", "S2A", "and", "S2B", "Fig", ")", ",", "as", "well", "as", "normal", "localization", "of", "apicobasal", "polarity", "proteins", "laminin", "subunit", "gamma", "1", "(", "LAMC1", ")", "and", "mucin", "1", "(", "MUC1", ")", "and", "adhesion", "molecules", "catenin", "beta", "1", "(", "CTNNB1", ")", "and", "E", "-", "cadherin", "(", "CDH1", ")", "(", "arrows", ",", "S2C", "and", "S2D", "Fig", ")", "in", "Lats1/2", "/", "Yap1PanKOTazHET", "pancreas", "at", "E12.5", "." ]

[ 1, 8, 1, 0, 8, 1, 8, 13, 11, 16, 8, 1, 0, 12, 8, 0, 8, 9, 8, 8, 13, 12, 13, 5, 0, 5, 0, 8, 9, 13, 12, 13, 13, 8, 13, 12, 5, 12, 12, 13, 13, 1, 2, 1, 0, 8, 1, 0, 8, 8, 8, 8, 8, 9, 13, 12, 13, 5, 8, 9, 13, 12, 13, 5, 8, 8, 8, 8, 9, 13, 12, 13, 5, 8, 8, 8, 13, 12, 13, 13, 8, 13, 12, 5, 12, 12, 13, 1, 12, 15, 12, 8, 1, 9, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 3, 4, 4, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 4, 0, 1, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 3, 4, 4, 0, 1, 0, 0, 3, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0 ]

[ "RNAi", ",", "RNA", "interference", ";", "RNAseq", ",", "RNA", "sequencing", "analysis", "." ]

[ 12, 13, 8, 8, 13, 12, 13, 8, 8, 8, 13 ]

[ 1, 0, 3, 4, 0, 1, 0, 3, 4, 4, 0 ]

[ "Relative", "to", "the", "public", ",", "the", "private", "saw", "4.1", "%", "(", "95", "%", "confidence", "interval", "[", "CI", "]", "2.9", "%", "to", "5.3", "%", ",", "p", "-", "value", "<", "0.001", ")", "and", "−8.7", "%", "(", "95", "%", "CI", "−9.7", "%", "to", "−7.7", "%", ",", "p", "-", "value", "<", "0.001", ")", "higher", "rates", "of", "improvement", "in", "TS", "and", "reduction", "in", "LTFU", ".", "Treatment", "outcomes", "did", "not", "improve", "in", "patients", "who", "experienced", "at", "least", "1", "transfer", "during", "their", "TB", "treatment", "." ]

[ 0, 10, 6, 8, 8, 6, 0, 16, 9, 8, 13, 9, 8, 8, 8, 17, 12, 17, 9, 8, 10, 9, 8, 8, 8, 8, 8, 1, 9, 13, 5, 9, 8, 13, 9, 8, 12, 9, 8, 10, 9, 8, 8, 8, 8, 8, 1, 9, 13, 0, 8, 1, 8, 1, 12, 5, 8, 1, 12, 13, 8, 8, 3, 10, 16, 1, 8, 11, 16, 2, 2, 9, 8, 1, 11, 12, 8, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0 ]

[ "This", "study", "evaluated", "the", "risk", "factors", "for", "delayed", "graft", "function", "(", "DGF", ")", "in", "a", "country", "where", "its", "incidence", "is", "high", ",", "detailing", "donor", "maintenance", "-", "related", "(", "DMR", ")", "variables", "and", "using", "machine", "learning", "(", "ML", ")", "methods", "beyond", "the", "traditional", "regression", "-", "based", "models", "." ]

[ 6, 8, 16, 6, 8, 8, 1, 16, 8, 8, 13, 12, 13, 1, 6, 8, 14, 11, 8, 3, 0, 13, 16, 8, 8, 13, 16, 13, 12, 13, 8, 5, 16, 8, 8, 13, 12, 13, 8, 1, 6, 0, 8, 13, 16, 8, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 4, 0, 1, 0, 0, 0, 0, 3, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "Definition", "of", "abbreviations", ":", "AX", "=", "area", "index", "of", "low", "frequent", "reactance", ";", "FEV1", "=", "forced", "expiratory", "volume", "at", "1", "second", ";", "FVC", "=", "forced", "vital", "capacity", ";", "pred", ".", "=", "predicted", ";", "R20", "=", "respiratory", "resistance", "at", "20", "Hz", ";", "R5", "=", "respiratory", "resistance", "at", "5", "Hz", ";", "X5", "=", "distal", "capacitive", "reactance", "at", "5", "Hz", ".", "p", "-", "values", "were", "tested", "by", "analysis", "of", "variance", "." ]

[ 8, 1, 8, 13, 12, 16, 8, 8, 1, 0, 0, 8, 13, 8, 16, 16, 0, 8, 1, 9, 8, 13, 8, 16, 16, 0, 8, 13, 8, 13, 16, 16, 13, 12, 16, 0, 8, 1, 9, 8, 13, 12, 16, 0, 8, 1, 9, 8, 13, 12, 16, 0, 0, 8, 1, 9, 8, 13, 8, 8, 8, 3, 16, 1, 8, 1, 8, 13 ]

[ 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 3, 4, 4, 4, 0, 1, 0, 0, 3, 4, 4, 4, 0, 1, 0, 0, 0, 3, 4, 4, 4, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "Well", "-", "conducted", "randomized", "controlled", "trials", "(", "RCTs", ")", "remain", "the", "gold", "standard", "for", "assessing", "medical", "interventions", "because", "their", "design", "controls", "both", "measured", "and", "unmeasured", "confounding", "variables", "." ]

[ 2, 13, 16, 0, 16, 8, 13, 12, 13, 16, 6, 0, 8, 1, 16, 0, 8, 14, 11, 8, 16, 5, 0, 5, 0, 16, 8, 13 ]

[ 0, 0, 0, 3, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "Unless", "stated", "otherwise", ",", "all", "cell", "culture", "reagents", "were", "purchased", "from", "Gibco", "(", "Thermo", "Fisher", "Scientific", ",", "Waltham", ",", "MA", ",", "USA", ")", ".", "Recombinant", "human", "TNFα", "was", "purchased", "from", "PeproTech", "(", "Rocky", "Hill", ",", "NJ", ",", "USA", ")", ".", "The", "SMAC", "mimetics", ",", "AZD", "5582", "dihydrochloride", ",", "birinapant", ",", "and", "the", "MLKL", "inhibitor", ",", "NSA", ",", "were", "purchased", "from", "Tocris", "Bioscience", "(", "Bristol", ",", "UK", ")", ".", "The", "pan", "-", "caspase", "inhibitor", ",", "Z", "-", "VAD", "-", "FMK", "(", "zVAD", ")", ",", "the", "RIPK1", "inhibitor", ",", "Nec-1s", ",", "and", "the", "RIP3", "inhibitor", ",", "gsk872", ",", "were", "purchased", "from", "Calbiochem", "(", "Merck", "Millipore", ",", "MA", ",", "USA", ")", ".", "Apoptosis", "kits", "(", "A5", "-", "FITC", "and", "A5", "-", "APC", ")", "were", "purchased", "from", "MBL", "International", "(", "Woburn", ",", "MA", ",", "USA", ")", ".", "Cell", "-", "impermeant", ",", "amine", "-", "reactive", "dye", "uptake", "(", "LD", "-", "Violet", ")", "was", "purchased", "from", "MolecularProbs", "(", "Thermo", "Fisher", "Scientific", ",", "Waltham", ",", "MA", ",", "USA", ")", ".", "Halt", "protease", "and", "the", "phosphatase", "inhibitor", "cocktail", "EDTA", "-", "free", "was", "purchased", "from", "Pierce", "Biotechnology", "(", "Thermo", "Fisher", "Scientific", ",", "Waltham", ",", "MA", ",", "USA", ")", ".", "Commercial", "antibodies", "were", "purchased", "from", "Abcam", "(", "Cambridge", ",", "UK", ")", "(", "anti", "-", "human", "-", "pMLKL", ",", "187091", ",", "and", "anti", "-", "mouse", "-", "pMLKL", ",", "196436", ")", ",", "Merck", "Millipore", "(", "total", "MLKL", ",", "MABC604", ")", ",", "BD", "(", "RIPK1", ",", "610458", ")", ",", "and", "from", "Cell", "Signaling", "Technology", "(", "Danvers", ",", "MA", ",", "USA", ")", "(", "cleaved", "caspase-3", ",", "9961", ")", "." ]

[ 14, 16, 2, 13, 6, 8, 8, 8, 3, 16, 1, 12, 13, 12, 12, 12, 13, 12, 13, 12, 13, 12, 13, 13, 0, 0, 12, 3, 16, 1, 12, 13, 12, 12, 13, 12, 13, 12, 13, 13, 6, 12, 8, 13, 12, 9, 8, 13, 8, 13, 5, 6, 12, 8, 13, 12, 13, 3, 16, 1, 12, 12, 13, 12, 13, 12, 13, 13, 6, 0, 0, 8, 8, 13, 12, 0, 12, 0, 12, 13, 12, 13, 13, 6, 12, 8, 13, 12, 13, 5, 6, 12, 8, 13, 8, 13, 3, 16, 1, 12, 13, 12, 12, 13, 12, 13, 12, 13, 13, 8, 8, 13, 12, 0, 12, 5, 12, 0, 12, 13, 3, 16, 1, 12, 12, 13, 12, 13, 12, 13, 12, 13, 13, 12, 0, 0, 13, 8, 0, 0, 8, 8, 13, 12, 0, 12, 13, 3, 16, 1, 12, 13, 12, 12, 12, 13, 12, 13, 12, 13, 12, 13, 13, 8, 8, 5, 6, 8, 8, 8, 12, 0, 0, 3, 16, 1, 12, 12, 13, 12, 12, 12, 13, 12, 13, 12, 13, 12, 13, 13, 0, 8, 3, 16, 1, 12, 13, 12, 13, 12, 13, 13, 0, 0, 0, 0, 12, 13, 9, 13, 5, 0, 0, 0, 0, 12, 13, 9, 13, 13, 12, 12, 13, 0, 12, 13, 9, 13, 13, 12, 13, 12, 13, 9, 13, 13, 5, 1, 12, 12, 12, 13, 12, 13, 12, 13, 12, 13, 13, 16, 8, 13, 9, 13, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 4, 4, 0, 1, 0, 0, 0, 1, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 1, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "Lastly", ",", "we", "found", "a", "strong", "negative", "correlation", "between", "KDM5B", "expression", "and", "STING", "expression", "in", "The", "Cancer", "Genome", "Atlas", "(", "TCGA", ")", "tumor", "samples", "." ]

[ 2, 13, 11, 16, 6, 0, 0, 8, 1, 8, 8, 5, 12, 8, 1, 6, 12, 12, 12, 13, 12, 13, 8, 8, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 3, 4, 4, 4, 0, 1, 0, 0, 0, 0 ]

[ "Flag", "-", "PGK1", "was", "overexpressed", "in", "HEK293", "T", "cells", "followed", "by", "treatment", "with", "nicotinamide", "(", "NAM", ",", "10", "mM", "for", "4", "hr", ")", ",", "trichostatin", "(", "TSA", ",", "5", "μM", "for", "12", "hr", ")", ",", "or", "NAM", "and", "TSA", "(", "N+T", ")", ".", "Acetylation", "levels", "and", "enzyme", "activity", "of", "Flag", "-", "bead", "-", "purified", "PGK1", "were", "determined", "by", "western", "blot", "analysis", "and", "enzyme", "assay", ",", "respectively", "." ]

[ 12, 13, 12, 3, 16, 1, 12, 12, 8, 16, 1, 8, 1, 8, 13, 12, 13, 9, 8, 1, 9, 8, 13, 13, 8, 13, 12, 13, 9, 8, 1, 9, 8, 13, 13, 5, 12, 5, 12, 13, 8, 13, 13, 8, 8, 5, 8, 8, 1, 12, 13, 8, 13, 16, 12, 3, 16, 1, 0, 8, 8, 5, 8, 8, 13, 2, 13 ]

[ 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "Results", "were", "generally", "similar", "using", "both", "general", "linear", "models", "(", "GLMs", ";", "see", "below", ")", "and", "general", "linear", "mixed", "models", "(", "GLMMs", ";", "see", "next", "paragraph", ")", "." ]

[ 8, 3, 2, 0, 16, 5, 0, 0, 8, 13, 12, 13, 16, 2, 13, 5, 0, 0, 16, 8, 13, 12, 13, 16, 0, 8, 13, 13 ]

[ 0, 0, 0, 0, 0, 0, 3, 4, 4, 0, 1, 0, 0, 0, 0, 0, 3, 4, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0 ]

[ "RTP", ",", "Arabidopsis", "thaliana", "ribulose", "bisphosphate", "carboxylase", "small", "subunit", "transit", "peptide", ";", "SaSSy", ",", "Santalum", "album", "santalene", "synthase", ";", "FPS", ",", "A.", "thaliana", "farnesyl", "diphosphate", "synthase", ";", "HMGR", ",", "A.", "thaliana", "3", "-", "hydroxy-3", "-", "methylglutaryl", "-", "CoA", "reductase", ";", "tHMGR", ",", "A.", "thaliana", "truncated", "HMGR", ".", "SaCYP76F39v1", ",", "Santalum", "album", "santalene", "/", "bergamotene", "oxidase(CYP76F39v1", ")", "." ]

[ 12, 13, 8, 8, 8, 8, 8, 0, 8, 8, 8, 13, 12, 13, 12, 8, 8, 8, 13, 12, 13, 8, 8, 8, 8, 8, 13, 12, 13, 8, 8, 8, 13, 8, 13, 8, 13, 8, 8, 13, 12, 13, 8, 8, 16, 12, 13, 12, 13, 12, 8, 8, 15, 8, 8, 13, 13 ]

[ 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 3, 4, 0, 1, 0, 0, 0, 3, 4, 4, 0, 1, 0, 0, 0, 3, 4, 4, 4, 4, 4, 4, 4, 0, 1, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "CVD", ",", "cardiovascular", "disease", ";", "SBP", ",", "systolic", "blood", "pressure", "." ]

[ 12, 13, 0, 8, 13, 12, 13, 0, 8, 8, 13 ]

[ 1, 0, 3, 4, 0, 1, 0, 3, 4, 4, 0 ]

[ "In", "the", "present", "study", ",", "we", "have", "compared", "the", "synergistic", ",", "anti", "-", "cancer", "effects", "of", "permeable", ",", "solid", "-", "lipid", "Cur", "particles", "(", "SLCP", ")", "and", "BBR", "on", "two", "different", "GB", "cell", "lines", "that", "were", "derived", "from", "human", "tissue", "(", "U-87MG", "and", "U-251MG", ")", ".", "We", "found", "that", "co", "-", "treatment", "of", "SLCP", "and", "BBR", "induced", "more", "DNA", "fragmented", "cells", ",", "increased", "reactive", "oxygen", "species", "(", "ROS", ")", ",", "induced", "mitochondrial", "dysfunction", ",", "reduced", "the", "number", "of", "mitochondria", "per", "cell", ",", "significantly", "declined", "of", "ATP", "levels", ",", "induced", "more", "cell", "death", "markers", ",", "increased", "apoptotic", "death", "and", "inhibited", "the", "PI3K", "/", "Akt", "/", "mTOR", "pathway", "more", "efficiently", "than", "either", "single", "treatment", "." ]

[ 1, 6, 0, 8, 13, 11, 3, 16, 6, 0, 13, 0, 8, 0, 8, 1, 0, 13, 0, 8, 8, 12, 8, 13, 12, 13, 5, 12, 1, 9, 0, 12, 8, 8, 14, 3, 16, 1, 0, 8, 13, 12, 5, 12, 13, 13, 11, 16, 14, 8, 8, 8, 1, 12, 5, 12, 16, 2, 8, 16, 8, 13, 16, 0, 8, 8, 13, 12, 13, 13, 16, 0, 8, 13, 16, 6, 8, 1, 8, 1, 8, 13, 2, 16, 1, 12, 8, 13, 16, 2, 8, 8, 8, 13, 16, 0, 8, 5, 16, 6, 12, 15, 8, 15, 12, 8, 2, 2, 1, 6, 0, 8, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 1, 0, 0, 1, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 1, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "Furthermore", ",", "we", "constructed", "VSV", "and", "VSV", "-", "ΔP", "expressing", "a", "variety", "of", "antigens", "including", "hemagglutinin", "-", "neuraminidase", "(", "HN", ")", "from", "Newcastle", "disease", "virus", "(", "NDV", ")", ",", "hemagglutinin", "(", "HA", ")", "from", "either", "a", "2009", "H1N1", "pandemic", "influenza", "virus", "(", "pdm/09", ")", "or", "the", "avian", "H7N9", ".", "VSV", "and", "VSV", "-", "ΔP", "incorporated", "the", "foreign", "antigens", "on", "their", "surface", "resulting", "in", "induction", "of", "robust", "neutralizing", "antibody", ",", "serum", "IgG", ",", "and", "hemagglutination", "inhibition", "(", "HAI", ")", "titers", "against", "their", "corresponding", "viruses", "." ]

[ 2, 13, 11, 16, 12, 5, 12, 13, 12, 16, 6, 8, 1, 8, 16, 8, 13, 8, 13, 12, 13, 1, 12, 8, 8, 13, 12, 13, 13, 8, 13, 12, 13, 1, 5, 6, 9, 12, 0, 8, 8, 13, 12, 13, 5, 6, 0, 12, 13, 12, 5, 12, 13, 12, 16, 6, 0, 8, 1, 11, 8, 16, 1, 8, 1, 0, 16, 8, 13, 8, 12, 13, 5, 8, 8, 13, 12, 13, 8, 1, 11, 16, 8, 13 ]

[ 0, 0, 0, 0, 1, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0 ]

[ "Where", "outcome", "units", "differed", "between", "studies", ",", "we", "converted", "results", "to", "a", "common", "unit", "using", "biomedical", "research", "conversion", "tables.[27", "]", "Some", "studies", "described", "one", "risk", "factor", "with", "multiple", "estimates", ",", "e.g.", "mean", "body", "mass", "index", "(", "BMI", ")", "and", "prevalence", "of", "overweight", "and", "obesity", "." ]

[ 14, 8, 8, 16, 1, 8, 13, 11, 16, 8, 1, 6, 0, 8, 16, 0, 8, 8, 8, 13, 6, 8, 16, 9, 8, 8, 1, 0, 8, 13, 17, 0, 8, 8, 8, 13, 12, 13, 5, 8, 1, 8, 5, 8, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "As", "expected", ",", "significant", "up", "-", "regulation", "of", "A2AR", "was", "observed", "in", "experiments", "in", "which", "CGS21680", "greatly", "enhanced", "the", "chemotactic", "peptide", "N", "-", "formyl", "-", "methionyl", "-", "leucyl", "-", "phenylalanine", "(", "fMLP)-stimulated", "cAMP", "production", "of", "in", "vivo", "-", "activated", "neutrophils", "isolated", "from", "inflamed", "lungs", "from", "wild", "-", "type", "mice", ",", "but", "not", "of", "naïve", "granulocytes", "obtained", "from", "the", "bone", "marrow", "of", "healthy", "wild", "-", "type", "control", "mice", "(", "Figure", "4B", ",", "left", "graph", ")", "." ]

[ 14, 16, 13, 0, 0, 13, 8, 1, 12, 3, 16, 1, 8, 1, 11, 12, 2, 16, 6, 0, 8, 8, 13, 8, 13, 8, 13, 8, 13, 8, 13, 12, 12, 8, 1, 1, 2, 13, 16, 8, 16, 1, 16, 8, 1, 0, 13, 8, 8, 13, 5, 10, 1, 0, 8, 16, 1, 6, 8, 8, 1, 0, 0, 13, 8, 8, 8, 13, 12, 9, 13, 0, 8, 13, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 4, 4, 4, 4, 4, 4, 0, 1, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "To", "ascertain", "whether", "the", "damaged", "chromatin", "-", "enriched", "Sam68", "is", "recruited", "to", "DNA", "lesions", "rather", "than", "generally", "bound", "to", "chromatin", ",", "we", "performed", "chromatin", "immunoprecipitation", "(", "ChIP", ")", "assays", "to", "monitor", "the", "DNA", "damage", "-", "triggered", "Sam68", "recruitment", "to", "the", "proximity", "of", "a", "DSB", "that", "is", "actively", "generated", "at", "a", "unique", "chromosomally", "integrated", "I", "-", "SceI", "site", "in", "HDR", "-", "GFP", "reporter", "U2OS", "cells", "(", "Fig", "3E", ")", ".", "While", "no", "association", "of", "Sam68", "or", "of", "PARP1", "was", "detected", "with", "chromatin", "near", "the", "I", "-", "SceI", "site", "in", "U2OS", "cells", "without", "I", "-", "SceI", "transfection", ",", "Sam68", "and", "PARP1", "were", "indeed", "enriched", "at", "the", "site", "near", "the", "generated", "DSB", "in", "the", "I", "-", "SceI", "-", "expressing", "U2OS", "reporter", "cells", "(", "Fig", "3E", ")", ".", "In", "contrast", ",", "we", "did", "not", "detect", "an", "enrichment", "of", "Sam68", "or", "PARP1", "at", "the", "site", "far", "away", "from", "the", "cut", "I", "-", "SceI", "site", "(", "Fig", "3E", ")", ",", "which", "suggests", "that", "Sam68", "and", "PARP1", "are", "specifically", "recruited", "to", "the", "DNA", "damage", "site", "." ]

[ 10, 16, 14, 6, 16, 8, 8, 16, 12, 3, 16, 1, 8, 8, 2, 1, 2, 16, 1, 8, 13, 11, 16, 8, 8, 13, 12, 13, 8, 1, 16, 6, 8, 8, 8, 16, 12, 8, 1, 6, 8, 1, 6, 12, 14, 3, 2, 16, 1, 6, 0, 2, 16, 8, 8, 8, 8, 1, 12, 8, 12, 8, 8, 8, 13, 8, 9, 13, 13, 14, 6, 8, 1, 12, 5, 1, 12, 3, 16, 1, 8, 1, 6, 8, 8, 8, 8, 1, 8, 8, 1, 8, 8, 8, 8, 13, 12, 5, 12, 3, 2, 16, 1, 6, 8, 1, 6, 16, 12, 1, 6, 8, 8, 8, 8, 16, 8, 8, 8, 13, 8, 9, 13, 13, 1, 8, 13, 11, 3, 10, 16, 6, 8, 1, 12, 5, 12, 1, 6, 8, 2, 2, 1, 6, 16, 8, 8, 8, 8, 13, 8, 9, 13, 13, 11, 16, 14, 12, 5, 12, 3, 2, 16, 1, 6, 8, 8, 8, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "For", "immunodetection", ",", "the", "blots", "were", "incubated", "overnight", "at", "4", "°", "C", "in", "PBS", "containing", "0.1", "%", "Tween-20", "and", "5", "%", "skim", "milk", "with", "primary", "antibodies", "raised", "against", "the", "following", "proteins", ":", "AT1R", "(", "Santa", "Cruz", "Biotechnology", ",", "Santa", "Cruz", ",", "CA", ")", ",", "Copper", "/", "zinc", "superoxide", "dismutase", "(", "Cu", ")", "(", "Enzo", "Life", "Sciences", ",", "Inc.", ",", "NY", ")", ",", "Manganese", "-", "superoxide", "dismutase", "(", "/ZnSODMnSOD", ")", ",", "catalase", ",", "type", "IV", "collagen", ",", "and", "SGLT2", "(", "all", "from", "Abcam", ")", ";", "β", "-", "actin", "(", "Sigma", "-", "Aldrich", ")", ";", "The", "second", "antibody", "was", "HRP", "-", "linked", "anti", "-", "Rabbit", "IgG", "(", "Cell", "Signaling", "Technology", ",", "Beverly", ",", "MA", ")", "for", "AT1R", ",", "Cu", ",", "/ZnSODSGLT2", ",", "and", "HPR", "-", "linked", "anti", "-", "Mouse", "IgG", "(", "Cell", "Signaling", "Technology", ")", "for", "MnSOD", "and", "β", "-", "actin", "." ]

[ 1, 8, 13, 6, 8, 3, 16, 2, 1, 9, 8, 8, 1, 12, 16, 9, 8, 12, 5, 9, 8, 0, 8, 1, 0, 8, 16, 1, 6, 0, 8, 13, 12, 13, 12, 12, 12, 13, 12, 12, 13, 12, 13, 13, 8, 15, 8, 8, 8, 13, 12, 13, 13, 12, 12, 12, 13, 12, 13, 12, 13, 13, 8, 8, 8, 8, 13, 12, 13, 13, 8, 13, 8, 9, 8, 13, 5, 12, 13, 11, 1, 12, 13, 13, 13, 8, 8, 13, 12, 8, 12, 13, 13, 6, 0, 8, 3, 8, 8, 16, 0, 8, 0, 12, 13, 12, 12, 12, 13, 12, 13, 12, 13, 1, 12, 13, 12, 13, 12, 13, 5, 8, 8, 16, 0, 8, 0, 12, 13, 12, 12, 12, 13, 1, 12, 5, 13, 8, 8, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 1, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0 ]

[ "As", "inosine", "base", "pairs", "with", "cytosine", ",", "A-to-IRNAediting", "levels", "can", "be", "measured", "as", "an", "A", "-", "to", "-", "G", "conversion", "in", "the", "cDNA", "by", "reverse", "transcription", "(", "RT", ")", "and", "PCR", ".", "We", "quantified", "RNA", "editing", "levels", "[", "G", "/", "(", "A", "+", "G", ")", "(", "%", ")", "]", "at", "selected", "editing", "sites", "(", "Fig", "2A", ")", "from", "direct", "sequencing", "chromatograms", "of", "the", "RT", "-", "PCR", "products", "(", "Fig", "2B", ")", ".", "In", "the", "transcripts", "coding", "TNKS", ",", "EIF2AK2", ",", "and", "PSMB2", ",", "A", "levels", "were", "increased", "by", "-to-IRNAeditingIFN", "treatment", "due", "to", "the", "induction", "of", "ADAR1p150", "(", "Fig", "2B", "and", "2C", ")", ".", "YTHDF1", "deficiency", "significantly", "reduced", "the", "IFN", "-", "mediated", "induction", "of", "editing", "levels", "at", "these", "sites", "(", "Fig", "2B", "and", "2C", ")", ",", "which", "is", "consistent", "with", "the", "attenuation", "of", "ADAR1p150", "induction", "by", "YTHDF1", "knockdown", "(", "Fig", "1C", ")", ".", "To", "illustrate", "a", "comprehensive", "picture", "of", "IFN", "-", "induced", "changes", "in", "A", "levels", ",", "we", "performed", "RNA", "-", "seq", "analysis", "in", "YTHDF1", "knockdown", "cells", "with", "3", "biological", "replicates", "." ]

[ 14, 8, 8, 8, 1, 8, 13, 12, 8, 3, 3, 16, 1, 6, 8, 13, 1, 13, 8, 8, 1, 6, 8, 1, 0, 8, 13, 12, 13, 5, 8, 13, 11, 16, 8, 8, 8, 13, 8, 15, 13, 8, 15, 8, 13, 13, 13, 13, 13, 1, 16, 8, 8, 13, 8, 9, 13, 1, 0, 8, 8, 1, 6, 12, 13, 8, 8, 13, 8, 9, 13, 13, 1, 6, 8, 16, 12, 13, 12, 13, 5, 8, 13, 12, 8, 3, 16, 1, 12, 8, 1, 1, 6, 8, 1, 8, 13, 8, 9, 5, 9, 13, 13, 12, 8, 2, 16, 6, 12, 13, 16, 8, 1, 8, 8, 1, 6, 8, 13, 8, 9, 5, 9, 13, 13, 11, 3, 0, 1, 6, 8, 1, 8, 8, 1, 12, 8, 13, 8, 9, 13, 13, 10, 16, 6, 0, 8, 1, 12, 13, 16, 8, 1, 12, 8, 13, 11, 16, 8, 13, 8, 8, 1, 12, 8, 8, 1, 9, 0, 8, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "(", "A", ")", "Yeast", "-", "two", "-", "hybrid", "(", "Y2H", ")", "assay", "of", "interactions", "of", "GEF1", "with", "the", "indicated", "PP2Cs", ".", "The", "indicated", "construct", "combinations", "were", "co", "-", "transformed", "into", "the", "yeast", "strain", "pJ69", "-", "4A." ]

[ 13, 17, 13, 8, 13, 9, 13, 8, 13, 12, 13, 8, 1, 8, 1, 12, 1, 6, 16, 12, 13, 6, 16, 8, 8, 3, 16, 13, 16, 1, 6, 8, 8, 8, 13, 8 ]

[ 0, 0, 0, 3, 4, 4, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "OCV", ",", "oral", "cholera", "vaccine", ";", "POUWT", ",", "point", "-", "of", "-", "use", "water", "treatment", "." ]

[ 12, 13, 0, 8, 8, 13, 12, 13, 8, 13, 1, 13, 8, 8, 8, 13 ]

[ 1, 0, 3, 4, 4, 0, 1, 0, 3, 4, 4, 4, 4, 4, 4, 0 ]

[ "Using", "rapid", "quench", "methods", ",", "we", "showed", "the", "phosphoryl", "transfer", "with", "CaATP", "was", "slower", "than", "with", "MgATP", ".", "Calcium", "could", "indeed", "support", "transfer", "of", "the", "γ", "-", "phosphoryl", "group", "either", "in", "the", "crystals", "or", "in", "solution", "even", "when", "adenosine-5'-(β", ",", "γ", "-", "imido)triphosphate", "(", "AMP-PNP", ")", "was", "used", "instead", "of", "ATP", ".", "This", "led", "us", "to", "reinvestigate", "how", "autophosphorylation", "of", "the", "RIIβ", "-", "subunit", "contributes", "specifically", "to", "the", "activation", "/", "inactivation", "cycle", "of", "the", "RIIβ", "holoenzyme", "and", "whether", "there", "is", "a", "difference", "between", "calcium", "and", "magnesium", "since", "both", "can", "support", "transfer", "of", "the", "phosphate", "." ]

[ 16, 0, 8, 8, 13, 11, 16, 6, 8, 8, 1, 12, 3, 0, 1, 1, 12, 13, 8, 3, 2, 16, 8, 1, 6, 13, 13, 8, 8, 5, 1, 6, 8, 5, 1, 8, 2, 14, 8, 13, 13, 13, 8, 13, 12, 13, 3, 16, 2, 1, 12, 13, 11, 16, 11, 1, 16, 14, 8, 1, 6, 8, 13, 8, 16, 2, 1, 6, 8, 15, 8, 8, 1, 6, 8, 8, 5, 14, 11, 16, 6, 8, 1, 8, 5, 8, 14, 11, 3, 16, 8, 1, 6, 8, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 4, 4, 0, 1, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "FITC", ",", "fluorescein", "isothiocyanate", ";", "GATI", ",", "VLYPNDPAAYAAYAPGTGGGATI", "-", "amide", "." ]

[ 12, 13, 8, 8, 13, 12, 13, 8, 13, 8, 13 ]

[ 1, 0, 3, 4, 0, 1, 0, 3, 4, 4, 0 ]

[ "The", "mitochondrial", "pathway", "is", "considered", "a", "mechanism", "to", "induce", "apoptosis", "in", "human", "umbilical", "vein", "endothelial", "cells", "(", "HUVECs", ")", "and", "glomerular", "endothelial", "cells", "[", "13", ",", "14", "]", "." ]

[ 6, 0, 8, 3, 16, 6, 8, 10, 16, 8, 1, 0, 0, 8, 0, 8, 13, 12, 13, 5, 0, 0, 8, 13, 9, 13, 9, 13, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "CI", ",", "confidence", "interval", ";", "PI", ",", "prediction", "interval", ";", "RE", ",", "random", "effects", "." ]

[ 12, 13, 8, 8, 13, 12, 13, 8, 8, 13, 12, 13, 0, 8, 13 ]

[ 1, 0, 3, 4, 0, 1, 0, 3, 4, 0, 0, 0, 0, 0, 0 ]

[ "To", "validate", "functionality", "of", "the", "engineered", "receptors", ",", "concentration", "response", "curves", "(", "10−12", "to", "10−5", ")", "for", "5-HT", "-", "mediated", "Cai2", "+", "release", "were", "generated", "(", "Fig", "4B", "and", "4C", ")", ".", "Serotonin", "-", "mediated", "Cai2", "+", "release", "was", "similar", "in", "cells", "transfected", "with", "the", "5", "-", "-HT2ARRLuc", "(", "Fig", "4B", ")", "or", "5", "-", "-HT2CReYFP", "(", "Fig", "4C", ")", "relative", "to", "cells", "transfected", "with", "WT", "5", "(", "Fig", "4B", ")", "or", "WT", "-HT2AR5", "(", "Fig", "4C", ")", ",", "respectively", "." ]

[ 10, 16, 8, 1, 6, 16, 8, 13, 8, 8, 8, 13, 9, 1, 9, 13, 1, 12, 13, 16, 8, 8, 8, 3, 16, 13, 8, 9, 5, 9, 13, 13, 8, 13, 16, 8, 8, 8, 3, 0, 1, 8, 16, 1, 6, 12, 13, 12, 13, 8, 9, 13, 5, 12, 13, 12, 13, 8, 9, 13, 0, 1, 8, 16, 1, 12, 12, 13, 8, 9, 13, 5, 12, 12, 13, 8, 9, 13, 13, 2, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 1, 0, 0, 0, 0, 0, 1, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0 ]

[ "Studies", "with", "Gram", "-", "negative", "pathogens", "showed", "that", "outer", "membrane", "vesicles", "(", "OMVs", ")", "are", "internalized", "into", "the", "host", "cell", "by", "endocytosis", ",", "but", "the", "entry", "mechanism", "for", "microbiota", "-", "derived", "vesicles", "is", "unknown", "." ]

[ 8, 1, 8, 13, 0, 8, 16, 14, 0, 8, 8, 13, 12, 13, 3, 16, 1, 6, 8, 8, 1, 8, 13, 5, 6, 8, 8, 1, 8, 13, 16, 8, 3, 0, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "Abbreviations", ":", "CI", ",", "confidence", "interval", ";", "MDS", ",", "Mediterranean", "Dietary", "Score", "." ]

[ 8, 13, 12, 13, 8, 8, 13, 12, 13, 12, 0, 8, 13 ]

[ 0, 0, 1, 0, 3, 4, 0, 1, 0, 3, 4, 4, 0 ]

[ "Vascular", "endothelial", "cadherin", "(", "VE-cadherin", ")", ",", "a", "major", "regulator", "of", "endothelial", "cell", "(", "EC", ")", "junctional", "integrity", "is", "strongly", "disorganized", "in", "ECs", "lining", "the", "CCM", "lesions", "." ]

[ 0, 0, 8, 13, 12, 13, 13, 6, 0, 8, 1, 0, 8, 13, 12, 13, 0, 8, 3, 2, 0, 1, 12, 16, 6, 12, 8, 13 ]

[ 3, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 3, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 1, 0, 0 ]

[ "CED", ":", "Chronic", "Energy", "Deficiency", ",", "IYCF", ":", "Infant", "Young", "Children", "Feeding", ",", "COR", ":", "Crude", "Odds", "Ratio", ",", "AORa", "=", "Adjusted", "Odds", "Ratio", "without", "LBW", ",", "P", "value", "b", "=", "P", "value", "without", "LBW", ",", "AORc", "=", "Adjusted", "Odds", "Ratio", "with", "LBW", ",", "P", "value", "d", "=", "P", "value", "with", "LBW", ",", "CI", "=", "Confidence", "Interval", ",", "adjusted", "variables", "were", "age", "of", "child", "bearing", ",", "maternal", "CED", "risk", "during", "pregnancy", ",", "maternal", "dietary", "diversity", ",", "frequency", "of", "ANC", "visit", "and", "knowledge", "during", "pregnancy", "." ]

[ 12, 13, 0, 8, 12, 13, 12, 13, 8, 0, 8, 8, 13, 12, 13, 8, 8, 8, 13, 8, 13, 12, 8, 8, 1, 12, 13, 8, 8, 8, 13, 8, 8, 1, 12, 13, 8, 13, 12, 8, 8, 1, 12, 13, 8, 8, 8, 13, 8, 8, 1, 12, 13, 12, 13, 8, 8, 13, 16, 8, 3, 8, 1, 8, 8, 13, 0, 12, 8, 1, 8, 13, 0, 0, 8, 13, 8, 1, 12, 8, 5, 8, 1, 8, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 1, 0, 3, 4, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "Hepatocellular", "carcinoma", "(", "HCC", ")", "is", "the", "fifth", "and", "seventh", "most", "common", "cancer", "in", "males", "and", "females", ",", "respectively", ",", "and", "accounts", "for", "at", "least", "700,000", "deaths", "worldwide", "annually", "[", "1", "]", "." ]

[ 0, 8, 13, 12, 13, 3, 6, 0, 5, 0, 2, 0, 8, 1, 8, 5, 8, 13, 2, 13, 5, 16, 1, 1, 2, 9, 8, 2, 2, 13, 9, 13, 13 ]

[ 3, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "AZT", ",", "azidothymidine", ";", "UTI", ",", "urinary", "tract", "infection" ]

[ 12, 13, 8, 13, 12, 13, 0, 8, 8 ]

[ 1, 0, 3, 0, 1, 0, 3, 4, 4 ]

[ "To", "investigate", "the", "role", "of", "Girdin", "in", "mTORC1", "signaling", ",", "we", "employed", "large", "-", "scale", "co", "-", "immunoprecipitation", "(", "co-IP", ")", "to", "isolate", "Girdin", "-", "interacting", "proteins", "in", "mouse", "brain", "lysate", "." ]

[ 10, 16, 6, 8, 1, 12, 1, 12, 8, 13, 11, 16, 0, 13, 8, 8, 13, 8, 13, 12, 13, 10, 16, 12, 13, 16, 8, 1, 8, 8, 8, 13 ]

[ 0, 0, 0, 0, 0, 1, 0, 1, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 0, 1, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "We", "functionally", "analyzed", "the", "activity", "of", "all", "5", "Arabidopsis", "thaliana", "MIR172", "genes", ",", "which", "encode", "miR172", "and", "promote", "the", "floral", "transition", "by", "inhibiting", "the", "accumulation", "of", "APETALA2", "(", "AP2", ")", "and", "APETALA2", "-", "LIKE", "(", "AP2", ")", "transcription", "factors", "(", "-LIKETFs", ")", "." ]

[ 11, 2, 16, 6, 8, 1, 6, 9, 12, 8, 8, 8, 13, 11, 16, 8, 5, 16, 6, 0, 8, 1, 16, 6, 8, 1, 12, 13, 12, 13, 5, 12, 13, 8, 13, 12, 13, 8, 8, 13, 12, 13, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 0, 1, 0, 0, 3, 4, 4, 0, 1, 0, 3, 4, 0, 1, 0, 0 ]

[ "A", "number", "of", "chromosomal", "loci", "associated", "with", "primary", "congenital", "glaucoma", "(", "PCG", ")", "have", "been", "identified", "in", "humans", "(", "OMIM", "231300", ",", "600975", ",", "613085", ",", "and", "613086", ")", "and", "mutations", "in", "the", "cytochrome", "P450", "gene", ",", "CYP1B1", ",", "and", "LTBP2", "gene", "at", "two", "of", "these", "loci", "were", "identified", "in", "families", "segregating", "PCG", "[", "6", ",", "7", "]", "." ]

[ 6, 8, 1, 0, 8, 16, 1, 0, 0, 8, 13, 12, 13, 3, 3, 16, 1, 8, 13, 12, 9, 13, 9, 13, 9, 13, 5, 9, 13, 5, 8, 1, 6, 8, 12, 8, 13, 12, 13, 5, 12, 8, 1, 9, 1, 6, 8, 3, 16, 1, 8, 16, 12, 13, 9, 13, 9, 13, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0 ]

[ "Abbreviations", ":", "RSI", "=", "Radiologic", "Severity", "Index", ";", "AUC", "=", "area", "under", "the", "ROC", "curve", ";", "ICU", "=", "intensive", "care", "unit" ]

[ 8, 13, 12, 13, 0, 12, 12, 13, 12, 13, 8, 1, 6, 12, 8, 13, 12, 13, 0, 8, 8 ]

[ 0, 0, 1, 0, 3, 4, 4, 0, 0, 0, 0, 0, 0, 1, 0, 0, 1, 0, 3, 4, 4 ]

[ "Thus", ",", "when", "the", "rat", "turns", "left", "after", "a", "preceding", "right", "turn", "run", ",", "the", "right", "TCC", "is", "still", "spiking", "and", "the", "left", "temporal", "context", "cell", "has", "not", "yet", "begun", "to", "fire", "." ]

[ 2, 13, 14, 6, 8, 16, 0, 1, 6, 16, 0, 8, 8, 13, 6, 0, 12, 3, 2, 16, 5, 6, 0, 0, 8, 8, 3, 10, 2, 16, 10, 16, 13 ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 3, 4, 4, 0, 0, 0, 0, 0, 0, 0 ]

[ "Tilmanocept", "accumulates", "in", "sentinel", "lymph", "nodes", "(", "SLN", ")", "by", "binding", "to", "a", "cell", "surface", "receptor", "unique", "to", "macrophages", "and", "dendritic", "cells", "." ]

[ 12, 16, 1, 0, 8, 8, 13, 12, 13, 1, 16, 1, 6, 8, 8, 8, 0, 1, 8, 5, 0, 8, 13 ]

[ 0, 0, 0, 3, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]