id
string
words
sequence
boxes
sequence
question
string
answer
string
634
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who conducted pivotal studies
Takeda
634
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What findings are not duplicated in mouse, monkey, or dog?
Rat Findings
638
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quantity of the product code 15102
1
412
[ "procucit", "brief", ".", ".", ".", "Here's", "another", "for", "the", "SON", "enemies", "list.", "..", "Nutritionally", "Fortified", "Beverage", "Mix", "\"The", "wholesome", "now", "experien'", "Sleve", "...", "SAMSON", "TY", "THE", "COCA-COLA", "COMPANY", "FOODS", "DIVISION", "HOUSTON,", "TEXAS", "Product", "Concept", "and", "Positioning:", "A", "fortified", "beverage", "mix,", "Samson,", "may", "substantially", "add", "to", "nutrition", "pro-", "grams", "in", "hospitals,", "schools", "and", "foodservice", "institutions.", "The", "product,", "originating", "in", "1966", "from", "a", "nutritional", "bev-", "erage", "program", "in", "underdeveloped", "countries", "undertaken", "by", "Coca-Cola,", "is", "now", "in", "test", "market", "as", "a", "noncarbonated", "beverage", "for", "U.S.", "foodservice", "use.", "Samson", "is", "positioned", "as", "a", "pleasant", "tasting,", "nutritious", "drink", "as", "a", "meal", "component", "an", "ounce.", "or", "snack", "for", "all", "age", "groups", "at", "a", "cost", "of", "less", "than", "a", "penny", "Ingredients", "and", "Description:", "Nutrient", "fortification", "added", "to", "sugar;", "partially", "delactosed", "and", "demineralized", "cheese", "whey;", "natural", "and", "artificial", "flavor,", "and", "artificial", "color", "to", "produce", "the", "instant", "high-protein", "content", "beverage", "mix.", "When", "reconstituted", "with", "water,", "an", "8-ounce", "serving", "pro-", "vides", "3.6", "grams", "of", "protein;", "100%", "of", "U.S.", "Recommended", "Dietary", "Allowance", "of", "vitamin", "C;", "25%", "RDA", "of", "vitamins", "A,", "D,", "E,", "thiamine,", "riboflavin,", "Be,", "and", "Bar,", "niacin,", "folic", "acid;", "and", "25%", "RDA", "of", "iron.", "The", "mix", "comes", "in", "a", "sealed", "foil/paper", "laminate", "bag", "for", "moisture", "protection.", "Varieties", "are", "orange,", "lemon,", "and", "tropical", "fruit.", "Packaging:", "The", "flavored", "mix", "dissolves", "instantly", "when", "stirred", "in", "either", "hot", "or", "cold", "water.", "One", "bag", "mixes", "with", "one", "gallon", "of", "water", "and", "can", "be", "stored", "under", "refrigeration", "for", "future", "use.", "The", "26-ounce", "bag", "yields", "17,", "eight", "fluid-", "ounce", "drinks.", "food", "product", "development", "-", "February,", "1974", "Source:", "https://www.industrydocuments.ucsf.edu/docs/hfpj0226" ]
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Where is the Coca-cola company foods division located?
Houston, Texas
414
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From which department the letter is issued?
Department of health, education, and welfare
414
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whose signature at the bottom of page ?
Alexander Grant
415
[ "PEPSI-COLA", "COMPANY", "PURCHASE", ".", "NEW", "YORK", "10577", "November", "14,", "1986", "Ms.", "Laurie", "Quint", "Center", "for", "Science", "in", "the", "Public", "Interest", "1501", "Sixteenth", "St.", "N.W.", "Washington,", "DC", "20036", "Dear", "Ms.", "Quint:", "Thank", "you", "for", "your", "recent", "letter", "to", "Pepsi-Cola", "requesting", "information", "about", "our", "products.", "A", "complete", "listing", "of", "the", "ingredients", "in", "our", "Pepsi", "products", "appears", "on", "each", "package.", "In", "answer", "to", "your", "question", "regarding", "the", "nutritional", "breakdown", "of", "our", "carbonated", "beverages,", "we", "are", "enclosing", "Product", "Ingredient", "Data", "Sheet.", "Please", "note", "that", "the", "amounts", "of", "sodium,", "potassium", "and", "calcium", "depend", "on", "the", "local", "water", "supply.", "Our", "independently", "owned", "and", "operated", "Pepsi-Cola", "franchise", "bottlers", "have", "the", "choice", "of", "using", "one", "of", "the", "sweeteners", "authorized", "for", "use", "by", "the", "Pepsi-Cola", "system.", "The", "bottlers", "primarily", "use", "sucrose", "and", "high", "fructose", "corn", "syrup.", "The", "sweetener", "used", "in", "Pepsi-Cola", "determines", "its", "exact", "caloric", "content.", "When", "sweetened", "with", "sucrose,", "Pepsi-Cola", "has", "13.1", "calories", "per", "ounce,", "or", "157", "calories", "in", "a", "12-ounce", "can.", "When", "sweetened", "with", "high", "fructose", "corn", "syrup,", "it", "contains", "13.3", "calories,", "for", "a", "total", "of", "160", "calories", "per", "12-ounce", "serving.", "The", "caloric", "content", "indicated", "on", "the", "enclosed", "sheet", "is", "for", "Pepsi-Cola", "sweetened", "with", "sucrose.", "This", "calculation", "is", "based", "on", "the", "standard", "multiplier", "of", "3.8", "calories", "per", "gram", "of", "carbohydrate.", "We", "appreciate", "your", "interest", "in", "Pepsi-Cola", "Company", "and", "its", "products", "and", "hope", "this", "information", "has", "been", "helpful", "to", "you.", "Sincerely", ",", "anita", "Pancatted", "Anita", "Pancotto", "Consumer", "Correspondent", "AP", "/es", "Enclosure", "Source:", "https://www.industrydocuments.ucsf.edu/docs/hjpj0226" ]
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what is the date mentioned at the top of the page?
November 14, 1986
415
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who is the consumer correspondent?
Anita Pancotto
417
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Who is this letter sent to?
Mr. Alm
417
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what is the designation of Mr.john r alm?
President and Chief Operating Officer
417
[ "Of", "HEALTH", "ATMENT", "OF", "H", "KIMAN", "SERVICES", "THE", "SECRETARY", "OF", "HEALTH", "AND", "HUMAN", "SERVICES", "WASHINGTON,", "D.C.", "20201", "OCT", "0", "3", "2003", "\\", "Mr.", "John", "R.", "Alm", "President", "and", "Chief", "Operating", "Officer", "Coca-Cola", "Enterprise,", "Inc.", "P.O.", "Box", "723040", "Atlanta,", "Georgia", "31", "139-0040", "Dear", "Mr.", "Alm:", "Thank", "you", "for", "your", "letter", "regarding", "our", "recent", "meeting", "concerning", "the", "nation's", "obesity", "epidemic.", "I", "appreciate", "your", "willingness", "to", "join", "with", "me", "in", "attacking", "this", "most", "serious", "public", "health", "concern.", "The", "five", "steps", "that", "Coca-cola", "Enterprises,", "Inc.", "is", "taking", "to", "address", "the", "obesity", "epidemic,", "especially", "among", "our", "nation's", "children,", "represents", "an", "important", "beginning", "and", "commitment.", "As", "we", "discussed,", "my", "prevention", "initiative,", "Steps", "To", "A", "HealthierUS,", "focuses", "on", "preventing", "obesity", "and", "such", "diseases", "as", "diabetes", "and", "asthma", "by", "promoting", "physical", "activity,", "good", "nutrition,", "and", "preventive", "health", "services.", "The", "initiative", "advances", "the", "President's", "HealthierUS", "goal", "of", "helping", "Americans", "live", "longer,", "better", "and", "healthier", "lives.", "The", "challenge", "is", "to", "create", "a", "comprehensive", "multifaceted", "public", "health", "approach", "capable", "of", "delivering", "long-term", "improvements", "in", "the", "lifestyles", "of", "Americans.", "Effective", "action", "requires", "the", "close", "cooperation", "and", "collaboration", "of", "a", "variety", "of", "corporate", "enterprises,", "organizations", "and", "individuals", "at", "all", "levels.", "Only", "with", "the", "support", "and", "investment", "from", "a", "broad", "array", "of", "public", "and", "private", "partners,", "such", "as", "yourself", "and", "others,", "will", "we", "succeed.", "I", "commend", "you", "for", "leadership", "in", "taking", "action", "to", "promote", "health", "beverage", "choice,", "nutrition", "education,", "and", "physical", "activity,", "especially", "for", "our", "children", "in", "and", "out", "of", "school.", "In", "addition", "to", "the", "actions", "that", "you", "mentioned,", "my", "staff", "tells", "me", "that", "your", "company", "is", "now", "selling", "8", "ounce", "bottles", "and", "cans", "of", "beverages.", "This", "seems", "to", "be", "an", "excellent", "way", "to", "draw", "attention", "to", "the", "importance", "of", "portion", "size", "and", "help", "consumers", "limit", "their", "intake", "of", "excess", "calories", "by", "controlling", "portion", "sizes.", ".", "I", "encourage", "you", "to", "continue", "your", "efforts", "and", "identify", "even", "more", "ways", "to", "help", "us", "decrease", "overweight", "and", "obesity", "in", "this", "country", "and", "I", "look", "forward", "to", "future", "collaborations", "Finally,", "on", "a", "separate", "note,", "I", "applaud", "your", "personal", "commitment", "to", "helping", "the", "children", "of", "Los", "Angeles", "build", "bright", "futures", "through", "Camp", "Paintrock,", "and", "I", "hope", "to", "take", "you", "up", "on", "your", "invitation", "to", "visit.", "Sincerely,", "Source:", "https://www.industrydocuments.ucsf.edu/docs/sfpj0226" ]
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what is the president's healthierUS goal ?
helping americans live longer, better and healthier lives.
417
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what is the reason to applaud Alm?
personal commitment to helping the children of los angeles build bright futures through camp paintrock
418
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what is the title of the page?
Sing With Me
418
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what happens if i sip on my coke while i sing my song according to letter?
it cools my throat
420
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where is the place of coca-cola companyas mentioned in the letterhead?
Atlanta, Georgia
421
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What is the letter dated?
November 1, 1972
421
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What is the designation of the sender in this letter?
public relations assistant
420
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Who is this letter addressed to?
Ms. Catherine Lerza
420
[ "The", "CocaCola", "Company", "ATLANTA,", "GEORGIA", "ADDRESS", "REPLY", "TO", "FIDELES", "KLOECKLER", "P.", "O.", "DRAWER", "1734", "PUBLIC", "RELATIONS", "DEPARTMENT", "ATLANTA,", "GA.", "30301", "November", "1,", "1972", "(404)", "897-2121", "Ms.", "Catherine", "Lerza", "Nutrition", "Coordinator", "Washington", "Ecology", "Center", "2000", "\"P\"", "Street,", "N.", "W.", ",", "Room", "612", "Washington,", "D.", "C.", "20036", "Dear", "Ms.", "Lerza:", "Our", "Research", "Department", "has", "shared", "with", "us", "your", "letter", "expressing", "interest", "in", "our", "development", "of", "protein", "beverages.", "We", "will", "be", "glad", "to", "attempt", "to", "answer", "your", "questions.", "The", "Coca-Cola", "Company", "for", "several", "years", "has", "been", "involved", "in", "the", "research", "and", "development", "of", "refreshing", "beverages", "that", "contain", "pro-", "tein,", "vitamins", "and", "minerals.", "The", "long-range", "objective", "of", "this", "program", "is", "to", "develop", "a", "variety", "of", "good-tasting", "nutritional", "beverages", "which", "would", "be", "compatible", "with", "different", "consumer", "food", "preferences", "around", "the", "world.", "In", "support", "of", "this", "objective,", "every", "effort", "is", "being", "made", "to", "utilize", "locally", "available", "protein", "sources.", "Considerable", "research", "and", "development", "relating", "to", "the", "composition", "and", "use", "of", "such", "products", "is", "well", "underway", "in", "many", "parts", "of", "the", "world,", "including", "the", "United", "States.", "However,", "the", "Latin", "America", "project", "is", "the", "most", "advanced", "to", "date.", "Three", "protein-containing", "beverages", "have", "been", "marketed", "by", "The", "Coca-cola", "Export", "Corporation,", "a", "subsidiary", "of", "The", "Coca-cola", "Company.", "Saci", "was", "the", "Company's", "first", "protein-containing", "beverage.", "Begin-", "ning", "in", "1968,", "it", "was", "test-marketed", "in", "chocolate", "and", "caramel", "flavors", "in", "suburbs", "of", "Rio", "de", "Janeiro,", "Brazil.", "The", "beverage", "was", "non-carbonated.", "The", "protein", "content", "was", "derived", "from", "Brazilian", "soybeans", "and", "seven", "vitamins", "were", "added.", "Brazil", "was", "selected", "for", "the", "test-market", "location", "because", "of", "ready", "availability", "of", "local", "soybeans", "as", "a", "protein", "source,", "local", "machinery", "and", "local", "talent", "to", "assist", "in", "the", "development", "and", "launching", "of", "the", "new", "product.", "A", "further", "consideration", "was", "the", "fact", "that", "the", "Company-", "owned", "bottling", "operation", "in", "Rio", "gave", "better", "flexibility", "in", "carrying", "out", "the", "experiment.", "Source:", "https://www.industrydocuments.ucsf.edu/docs/phpj0226" ]
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what was the company's first protein containing beverage?
Saci
421
[ "Ms.", "Catherine", "Lerza", "Washington", "Ecology", "Center", "-3-", "November", "1,", "1972", "combination", "per", "child)", ".", "The", "product", "has", "been", "provided", "free", "of", "charge", "to", "several", "Atlanta", "schools", "for", "several", "months", "and", "student", "acceptance", "has", "been", "good.", "Again,", "we", "appreciate", "your", "interest", "in", "our", "developments", "and", "hope", "the", "above", "will", "be", "helpful.", "Sincerely", ",", "(han", ")", "Silver", "/Flockly", "Public", "Relations", "Assistant", "FK:sga", "Source:", "https://www.industrydocuments.ucsf.edu/docs/phpj0226" ]
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what is the page number mentioned in this letter?
-3-
437
[ "ARRI1", "1987", "SOFTDRINKS", "AND", "CAFFEINE", ".", ".", "1", "Soft", "Drink", "Ingredient", "Series", "Source:", "https://www.industrydocuments.ucsf.edu/docs/pkpj0226" ]
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What sort of document series does it covers ?
Soft Drink Ingredient Series
437
[ "ARRI1", "1987", "SOFTDRINKS", "AND", "CAFFEINE", ".", ".", "1", "Soft", "Drink", "Ingredient", "Series", "Source:", "https://www.industrydocuments.ucsf.edu/docs/pkpj0226" ]
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What is the title of the series?
SOFT DRINKS AND CAFFEINE
437
[ "ARRI1", "1987", "SOFTDRINKS", "AND", "CAFFEINE", ".", ".", "1", "Soft", "Drink", "Ingredient", "Series", "Source:", "https://www.industrydocuments.ucsf.edu/docs/pkpj0226" ]
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What is the title of the document?
SOFT DRINKS AND CAFFEINE
455
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What is the fullform of ils?
international litigation services
455
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What type of certification is mentioned in this document?
CERTIFICATION OF TRANSLATION
455
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Who is the Managing Director of International Litigation Services, Inc?
joseph thorpe
439
[ "JUL-03-2008", "10:26", "FDA/CFSAN/ONPLDS", "301", "436", "2639", "P.", "01", ".", ".", "FDA", "CFSAN", "FOOD", "&", "DRUG", "ADMINISTRATION", "CENTER", "FOR", "FOOD", "SAFETY", "&", "APPLIED", "NUTRITION", "OFFICE", "OF", "NUTRITIONAL", "PRODUCTS,", "LABELING", "&", "DIETARY", "SUPPLEMENTS", "(HFS-200)", "5100", "Paint", "Branch", "Parkway", "College", "Park,", "MD", "20740", "TELEPHONE", "NUMBER:", "301/436-2373", "FAX", "NUMBER:", "301/436-2636", "DATE:", "1/", "3", "/", "08", "TO:", "rickion", "FAX", "NUMBER:", "2020", "12", "-", "3", "31-", "2054", ".", "FROM:", "COMMENTS:", "..", ".", "..", ".", "..", ".", ".", ".", ".", ".", "Received", "07-03-2008", "11:07", "am", "From", "301", "436", "2639", "Page", "001", "Source:", "https://www.industrydocuments.ucsf.edu/docs/rxpj0226" ]
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What is the Telephone Number given?
301/436-2373
441
[ "HFCSF", "JUL-03-2008", "10:26", "FDA/CFSAN/ONPLDS", "301", "436", "2659", "DEPARTMENT", "OF", "HEALTH", "&", "HUMAN", "SERVICES", "Public", "Health", "Service", "Food", "and", "Drug", "Administration", "College", "Park,", "MD", "20740", ".", ".'", "Audrae", "Erickson", "JUL", "0", "3", "2008", "President", "Com", "Refiners", "Association", "1701", "Pennsylvania", "Avenue,", "N.W.", "Suito", "950", "Washington,", "DC", "20006-5805", ":", "Dear", "Ms.", "Erickson:.", "This", "is", "in", "follow", "up", "to", "the", "meeting", "of", "April", "16,", "2008,", "between", "the", "Corn", "Refiners", "Association", "and", "the", "Center", "for", "Food", "Safety", "and", "Applied", "Nutrition", "(CFSAN).", "The", "meeting", "was", "prompted", "by", "a", "Food", "Navigator-[JSA.com", "article", "on", "the", "use", "of", "the", "term", "\"natural\"", "on", "products", "containing", "high", "fructose", "com", "syrup", "(HFCS).", "You", "asked", "CFSAN", "to", "reconsider", "its", "position", "on", "whether", "the", "use", "of", "the", "term", "\"natural\"", "can", "be", "used", "to", "describe", "products", "containing", "HFCS.", "At", "the", "meeting", "Mr.", "Empie", "of", "Archer", "Daniels", "Midland", "Company", "described", "the", "manufacturing", "process", "used", "to", "make", "HFCS", "and", "following", "the", "meeting", "you", "sent", "CFSAN", "a", "written", "description", "of", "this", "production", "process.", "During", "the", "meeting,", "we", "stated", "that", "our", "longstanding", "policy", "on", "the", "use", "of", "the", "term", "\"natural\"", "is", "that", "\"natural\"", "means", "that", "nothing", "artificial", "(including", "artificial", "flavors)", "or", "synthetic", "(including", "all", "color", "additives", "regardless", "of", "source)", "has", "been", "included", "in", "or", "has", "been", "added", "to", "a", "food", "that", "would", "not", "normally", "be", "expected", "to", "be", "in", "the", "food.", "Additionally,", "we", "stated", "that", "we", "do", "not", "restrict", "the", "use", "of", "the", "term", "\"natural\"", "except", "on", "products", "that", "contain", "added", "color,", "synthetic", "substances", "and", "flavors", "as", "provided", "for", "n", "Title", "21", "of", "the", "Code", "of", "Federal", "Regulations", "(CFR),", "section", "101.22.", "After", "reviewing", "the", "information", "about", "the", "HFCS", "production", "process", "that", "you", "provided,", "it", "is", "our", "understanding", "that", "the", "enzyme", "used", "to", "make", "HFCS", "is", "fixed", "to", "a", "column", "by", "the", "use", "of", "the", "synthetic", "fixing", "agent,", "glutaraldehyde.", "Any", "unreacted", "glutaraldehyde", "is", "removed", "by", "washing", "the", "column", "prior", "to", "the", "addition", "of", "the", "high", "dextrose", "equivalent", "com", "starch", "hydrolysate,", "which", "undergoes", "enzymatic", "reaction", "to", "produce", "HFCS.", "Because", "the", "glutaraldehyde", "does", "not", "come", "into", "contact", "with", "the", "high", "dextrose", "equivalent", "corn", "starch", "hydrolysate,", "it", "would", "not", "be", "considered", "to", "be", "included", "in", "or", "added", "to", "the", "HFCS.", "Therefore,", "we", "would", "not", "object", "to", "the", "use", "of", "the", "term", "\"natural\"", "on", "a", "product", "containing", "the", "HFCS", "produced", "by", "the", "manufacturing", "process", "described", "by", "Mr.", "Empie.", "However,", "we", "would", "object", "to", "the", "use", "of", "the", "term", "\"natural\"", "on", "a", "product", "containing", "HFCS", "that", "has", "a", "synthetic", "substance", "such", "as", "a", "synthetic", "fixing", "agent", "included", "in", "or", "added", "to", "it.", "We", "would", "also", "object", "to", "the", "use", "of", "the", "term", "\"natural\"", "on", "a", "product", "containing", "HFCS", "if", "the", "acids", "used", "to", "obtain", "the", "starch", "hydrolysate", "do", "not", "fit", "within", "our", "policy", "on", "\"natural\"", "as", "stated", "above.", ":", ".", ".", "Received", ".", "07-03-2008", ":11:07am", "From-301", "436", "2639", "Paga", "002", "Source:", "https://www.industrydocuments.ucsf.edu/docs/rxpj0226" ]
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What is the full form of CFSAN?
Center for Food Safety and Applied Nutrition
441
[ "HFCSF", "JUL-03-2008", "10:26", "FDA/CFSAN/ONPLDS", "301", "436", "2659", "DEPARTMENT", "OF", "HEALTH", "&", "HUMAN", "SERVICES", "Public", "Health", "Service", "Food", "and", "Drug", "Administration", "College", "Park,", "MD", "20740", ".", ".'", "Audrae", "Erickson", "JUL", "0", "3", "2008", "President", "Com", "Refiners", "Association", "1701", "Pennsylvania", "Avenue,", "N.W.", "Suito", "950", "Washington,", "DC", "20006-5805", ":", "Dear", "Ms.", "Erickson:.", "This", "is", "in", "follow", "up", "to", "the", "meeting", "of", "April", "16,", "2008,", "between", "the", "Corn", "Refiners", "Association", "and", "the", "Center", "for", "Food", "Safety", "and", "Applied", "Nutrition", "(CFSAN).", "The", "meeting", "was", "prompted", "by", "a", "Food", "Navigator-[JSA.com", "article", "on", "the", "use", "of", "the", "term", "\"natural\"", "on", "products", "containing", "high", "fructose", "com", "syrup", "(HFCS).", "You", "asked", "CFSAN", "to", "reconsider", "its", "position", "on", "whether", "the", "use", "of", "the", "term", "\"natural\"", "can", "be", "used", "to", "describe", "products", "containing", "HFCS.", "At", "the", "meeting", "Mr.", "Empie", "of", "Archer", "Daniels", "Midland", "Company", "described", "the", "manufacturing", "process", "used", "to", "make", "HFCS", "and", "following", "the", "meeting", "you", "sent", "CFSAN", "a", "written", "description", "of", "this", "production", "process.", "During", "the", "meeting,", "we", "stated", "that", "our", "longstanding", "policy", "on", "the", "use", "of", "the", "term", "\"natural\"", "is", "that", "\"natural\"", "means", "that", "nothing", "artificial", "(including", "artificial", "flavors)", "or", "synthetic", "(including", "all", "color", "additives", "regardless", "of", "source)", "has", "been", "included", "in", "or", "has", "been", "added", "to", "a", "food", "that", "would", "not", "normally", "be", "expected", "to", "be", "in", "the", "food.", "Additionally,", "we", "stated", "that", "we", "do", "not", "restrict", "the", "use", "of", "the", "term", "\"natural\"", "except", "on", "products", "that", "contain", "added", "color,", "synthetic", "substances", "and", "flavors", "as", "provided", "for", "n", "Title", "21", "of", "the", "Code", "of", "Federal", "Regulations", "(CFR),", "section", "101.22.", "After", "reviewing", "the", "information", "about", "the", "HFCS", "production", "process", "that", "you", "provided,", "it", "is", "our", "understanding", "that", "the", "enzyme", "used", "to", "make", "HFCS", "is", "fixed", "to", "a", "column", "by", "the", "use", "of", "the", "synthetic", "fixing", "agent,", "glutaraldehyde.", "Any", "unreacted", "glutaraldehyde", "is", "removed", "by", "washing", "the", "column", "prior", "to", "the", "addition", "of", "the", "high", "dextrose", "equivalent", "com", "starch", "hydrolysate,", "which", "undergoes", "enzymatic", "reaction", "to", "produce", "HFCS.", "Because", "the", "glutaraldehyde", "does", "not", "come", "into", "contact", "with", "the", "high", "dextrose", "equivalent", "corn", "starch", "hydrolysate,", "it", "would", "not", "be", "considered", "to", "be", "included", "in", "or", "added", "to", "the", "HFCS.", "Therefore,", "we", "would", "not", "object", "to", "the", "use", "of", "the", "term", "\"natural\"", "on", "a", "product", "containing", "the", "HFCS", "produced", "by", "the", "manufacturing", "process", "described", "by", "Mr.", "Empie.", "However,", "we", "would", "object", "to", "the", "use", "of", "the", "term", "\"natural\"", "on", "a", "product", "containing", "HFCS", "that", "has", "a", "synthetic", "substance", "such", "as", "a", "synthetic", "fixing", "agent", "included", "in", "or", "added", "to", "it.", "We", "would", "also", "object", "to", "the", "use", "of", "the", "term", "\"natural\"", "on", "a", "product", "containing", "HFCS", "if", "the", "acids", "used", "to", "obtain", "the", "starch", "hydrolysate", "do", "not", "fit", "within", "our", "policy", "on", "\"natural\"", "as", "stated", "above.", ":", ".", ".", "Received", ".", "07-03-2008", ":11:07am", "From-301", "436", "2639", "Paga", "002", "Source:", "https://www.industrydocuments.ucsf.edu/docs/rxpj0226" ]
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Which department is mentioned in the letter head?
DEPARTMENT OF HEALTH & HUMAN SERVICES
441
[ "HFCSF", "JUL-03-2008", "10:26", "FDA/CFSAN/ONPLDS", "301", "436", "2659", "DEPARTMENT", "OF", "HEALTH", "&", "HUMAN", "SERVICES", "Public", "Health", "Service", "Food", "and", "Drug", "Administration", "College", "Park,", "MD", "20740", ".", ".'", "Audrae", "Erickson", "JUL", "0", "3", "2008", "President", "Com", "Refiners", "Association", "1701", "Pennsylvania", "Avenue,", "N.W.", "Suito", "950", "Washington,", "DC", "20006-5805", ":", "Dear", "Ms.", "Erickson:.", "This", "is", "in", "follow", "up", "to", "the", "meeting", "of", "April", "16,", "2008,", "between", "the", "Corn", "Refiners", "Association", "and", "the", "Center", "for", "Food", "Safety", "and", "Applied", "Nutrition", "(CFSAN).", "The", "meeting", "was", "prompted", "by", "a", "Food", "Navigator-[JSA.com", "article", "on", "the", "use", "of", "the", "term", "\"natural\"", "on", "products", "containing", "high", "fructose", "com", "syrup", "(HFCS).", "You", "asked", "CFSAN", "to", "reconsider", "its", "position", "on", "whether", "the", "use", "of", "the", "term", "\"natural\"", "can", "be", "used", "to", "describe", "products", "containing", "HFCS.", "At", "the", "meeting", "Mr.", "Empie", "of", "Archer", "Daniels", "Midland", "Company", "described", "the", "manufacturing", "process", "used", "to", "make", "HFCS", "and", "following", "the", "meeting", "you", "sent", "CFSAN", "a", "written", "description", "of", "this", "production", "process.", "During", "the", "meeting,", "we", "stated", "that", "our", "longstanding", "policy", "on", "the", "use", "of", "the", "term", "\"natural\"", "is", "that", "\"natural\"", "means", "that", "nothing", "artificial", "(including", "artificial", "flavors)", "or", "synthetic", "(including", "all", "color", "additives", "regardless", "of", "source)", "has", "been", "included", "in", "or", "has", "been", "added", "to", "a", "food", "that", "would", "not", "normally", "be", "expected", "to", "be", "in", "the", "food.", "Additionally,", "we", "stated", "that", "we", "do", "not", "restrict", "the", "use", "of", "the", "term", "\"natural\"", "except", "on", "products", "that", "contain", "added", "color,", "synthetic", "substances", "and", "flavors", "as", "provided", "for", "n", "Title", "21", "of", "the", "Code", "of", "Federal", "Regulations", "(CFR),", "section", "101.22.", "After", "reviewing", "the", "information", "about", "the", "HFCS", "production", "process", "that", "you", "provided,", "it", "is", "our", "understanding", "that", "the", "enzyme", "used", "to", "make", "HFCS", "is", "fixed", "to", "a", "column", "by", "the", "use", "of", "the", "synthetic", "fixing", "agent,", "glutaraldehyde.", "Any", "unreacted", "glutaraldehyde", "is", "removed", "by", "washing", "the", "column", "prior", "to", "the", "addition", "of", "the", "high", "dextrose", "equivalent", "com", "starch", "hydrolysate,", "which", "undergoes", "enzymatic", "reaction", "to", "produce", "HFCS.", "Because", "the", "glutaraldehyde", "does", "not", "come", "into", "contact", "with", "the", "high", "dextrose", "equivalent", "corn", "starch", "hydrolysate,", "it", "would", "not", "be", "considered", "to", "be", "included", "in", "or", "added", "to", "the", "HFCS.", "Therefore,", "we", "would", "not", "object", "to", "the", "use", "of", "the", "term", "\"natural\"", "on", "a", "product", "containing", "the", "HFCS", "produced", "by", "the", "manufacturing", "process", "described", "by", "Mr.", "Empie.", "However,", "we", "would", "object", "to", "the", "use", "of", "the", "term", "\"natural\"", "on", "a", "product", "containing", "HFCS", "that", "has", "a", "synthetic", "substance", "such", "as", "a", "synthetic", "fixing", "agent", "included", "in", "or", "added", "to", "it.", "We", "would", "also", "object", "to", "the", "use", "of", "the", "term", "\"natural\"", "on", "a", "product", "containing", "HFCS", "if", "the", "acids", "used", "to", "obtain", "the", "starch", "hydrolysate", "do", "not", "fit", "within", "our", "policy", "on", "\"natural\"", "as", "stated", "above.", ":", ".", ".", "Received", ".", "07-03-2008", ":11:07am", "From-301", "436", "2639", "Paga", "002", "Source:", "https://www.industrydocuments.ucsf.edu/docs/rxpj0226" ]
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Who is the President of Corn Refiners Association?
Audrae Erickson
441
[ "HFCSF", "JUL-03-2008", "10:26", "FDA/CFSAN/ONPLDS", "301", "436", "2659", "DEPARTMENT", "OF", "HEALTH", "&", "HUMAN", "SERVICES", "Public", "Health", "Service", "Food", "and", "Drug", "Administration", "College", "Park,", "MD", "20740", ".", ".'", "Audrae", "Erickson", "JUL", "0", "3", "2008", "President", "Com", "Refiners", "Association", "1701", "Pennsylvania", "Avenue,", "N.W.", "Suito", "950", "Washington,", "DC", "20006-5805", ":", "Dear", "Ms.", "Erickson:.", "This", "is", "in", "follow", "up", "to", "the", "meeting", "of", "April", "16,", "2008,", "between", "the", "Corn", "Refiners", "Association", "and", "the", "Center", "for", "Food", "Safety", "and", "Applied", "Nutrition", "(CFSAN).", "The", "meeting", "was", "prompted", "by", "a", "Food", "Navigator-[JSA.com", "article", "on", "the", "use", "of", "the", "term", "\"natural\"", "on", "products", "containing", "high", "fructose", "com", "syrup", "(HFCS).", "You", "asked", "CFSAN", "to", "reconsider", "its", "position", "on", "whether", "the", "use", "of", "the", "term", "\"natural\"", "can", "be", "used", "to", "describe", "products", "containing", "HFCS.", "At", "the", "meeting", "Mr.", "Empie", "of", "Archer", "Daniels", "Midland", "Company", "described", "the", "manufacturing", "process", "used", "to", "make", "HFCS", "and", "following", "the", "meeting", "you", "sent", "CFSAN", "a", "written", "description", "of", "this", "production", "process.", "During", "the", "meeting,", "we", "stated", "that", "our", "longstanding", "policy", "on", "the", "use", "of", "the", "term", "\"natural\"", "is", "that", "\"natural\"", "means", "that", "nothing", "artificial", "(including", "artificial", "flavors)", "or", "synthetic", "(including", "all", "color", "additives", "regardless", "of", "source)", "has", "been", "included", "in", "or", "has", "been", "added", "to", "a", "food", "that", "would", "not", "normally", "be", "expected", "to", "be", "in", "the", "food.", "Additionally,", "we", "stated", "that", "we", "do", "not", "restrict", "the", "use", "of", "the", "term", "\"natural\"", "except", "on", "products", "that", "contain", "added", "color,", "synthetic", "substances", "and", "flavors", "as", "provided", "for", "n", "Title", "21", "of", "the", "Code", "of", "Federal", "Regulations", "(CFR),", "section", "101.22.", "After", "reviewing", "the", "information", "about", "the", "HFCS", "production", "process", "that", "you", "provided,", "it", "is", "our", "understanding", "that", "the", "enzyme", "used", "to", "make", "HFCS", "is", "fixed", "to", "a", "column", "by", "the", "use", "of", "the", "synthetic", "fixing", "agent,", "glutaraldehyde.", "Any", "unreacted", "glutaraldehyde", "is", "removed", "by", "washing", "the", "column", "prior", "to", "the", "addition", "of", "the", "high", "dextrose", "equivalent", "com", "starch", "hydrolysate,", "which", "undergoes", "enzymatic", "reaction", "to", "produce", "HFCS.", "Because", "the", "glutaraldehyde", "does", "not", "come", "into", "contact", "with", "the", "high", "dextrose", "equivalent", "corn", "starch", "hydrolysate,", "it", "would", "not", "be", "considered", "to", "be", "included", "in", "or", "added", "to", "the", "HFCS.", "Therefore,", "we", "would", "not", "object", "to", "the", "use", "of", "the", "term", "\"natural\"", "on", "a", "product", "containing", "the", "HFCS", "produced", "by", "the", "manufacturing", "process", "described", "by", "Mr.", "Empie.", "However,", "we", "would", "object", "to", "the", "use", "of", "the", "term", "\"natural\"", "on", "a", "product", "containing", "HFCS", "that", "has", "a", "synthetic", "substance", "such", "as", "a", "synthetic", "fixing", "agent", "included", "in", "or", "added", "to", "it.", "We", "would", "also", "object", "to", "the", "use", "of", "the", "term", "\"natural\"", "on", "a", "product", "containing", "HFCS", "if", "the", "acids", "used", "to", "obtain", "the", "starch", "hydrolysate", "do", "not", "fit", "within", "our", "policy", "on", "\"natural\"", "as", "stated", "above.", ":", ".", ".", "Received", ".", "07-03-2008", ":11:07am", "From-301", "436", "2639", "Paga", "002", "Source:", "https://www.industrydocuments.ucsf.edu/docs/rxpj0226" ]
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When was this letter received?
07-03-2008
426
[ "Boxs'", "Life", "July", "28,", "1972", "271", "MADISON", "AVE.", "NEW", "YORK", "N.", "Y.", "10016", "212", "LE2-", "0985", "Michael", "F.", "Jacobson,", "Ph.", "D.", "Center", "for", "Science", "in", "the", "Public", "Interest", "1346", "Connecticut", "Avenue,", "N.", "W.", "Room", "812", "Washington,", "D.", "C.", "20036", "Dear", "Dr.", "Jacobson:", "Attached", "is", "a", "copy", "of", "the", "information", "on", "soft", "drinks", "produced", "by", "our", "Reader", "Panel", "studies.", "This", "should", "contain", "the", "information", "you", "require.", "Cordially,", "RLG:j1", "Robert", "L.", "Goldsmith", "Att.", "Marketing", "Director", "THE", "NATIONAL", "MAGAZINE", "FOR", "ALL", "BOYS", "PUBLISHED", "BY", "THE", "BOY", "SCOUTS", "OF", "AMERICA", "Source:", "https://www.industrydocuments.ucsf.edu/docs/Ihpj0226" ]
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What is the date mentioned in the letter?
July 28, 1972
439
[ "JUL-03-2008", "10:26", "FDA/CFSAN/ONPLDS", "301", "436", "2639", "P.", "01", ".", ".", "FDA", "CFSAN", "FOOD", "&", "DRUG", "ADMINISTRATION", "CENTER", "FOR", "FOOD", "SAFETY", "&", "APPLIED", "NUTRITION", "OFFICE", "OF", "NUTRITIONAL", "PRODUCTS,", "LABELING", "&", "DIETARY", "SUPPLEMENTS", "(HFS-200)", "5100", "Paint", "Branch", "Parkway", "College", "Park,", "MD", "20740", "TELEPHONE", "NUMBER:", "301/436-2373", "FAX", "NUMBER:", "301/436-2636", "DATE:", "1/", "3", "/", "08", "TO:", "rickion", "FAX", "NUMBER:", "2020", "12", "-", "3", "31-", "2054", ".", "FROM:", "COMMENTS:", "..", ".", "..", ".", "..", ".", ".", ".", ".", ".", "Received", "07-03-2008", "11:07", "am", "From", "301", "436", "2639", "Page", "001", "Source:", "https://www.industrydocuments.ucsf.edu/docs/rxpj0226" ]
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What is the fulll form of FDA?
Food & Drug Administration
435
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What are the scheduled public gatherings on?
food labeling
435
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How much percent of consumers reads labels?
20%
435
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What is the heading of the document?
memorandum of meeting
443
[ "ATRRI", "1", "9:87", "Soft", "drinks", "are", "simple", "products.", "The", "main", "ingredient", "is", "carbonated", "water.", "Other", "ingredients", "are", "identified", "-", ".", ".", "WHAT'S", "IN", "on", "the", "label", "in", "decreasing", "order", "of", "amount.", "The", "data", "included", "in", "this", "pamphlet", "SOFT", "are", "for", "those", "who", "want", "more", "detailed", "information.", "Values", "listed", "herein", "represent", "typical", "ranges", "for", "various", "DRINKS", "categories", "of", "major,", "nationally", "distributed", "brands", "of", "soft", "drinks.", "More", "information", "about", "any", "of", "these", "ingredients", "may", "be", "obtained", "from", "the", "National", "Soft", "Drink", "Association", "1101", "16th", "Street,", "N.W.", "..", "..", ".", "Washington,", "D.C.", "20036", "(202)", "463-6750", "National", "Soft", "Drink", "Association", "1101", "16th", "Street,", "N.W.", "Washington,", "D.C.", "20036", "12/86", "(202)", "463-6732", "Soft", "Drink", "Ingredient", "Series", "Source:", "https://www.industrydocuments.ucsf.edu/docs/pkpj02:26" ]
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what is the main ingredient of soft drink?
Carbonated Water
438
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What is are the words written in bold in second paragraph?
Caffeine and Other Alleged Health Related Effects
443
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What is the heading in right corner ?
What's in Soft Drinks
438
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What is the second reference mentioned?
PepsiCo, Inc., The Physical or Technical Effect of Caffeine in Cola Beverages, Purchase, N.Y., July 20, 1981
438
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Which university does the sixth reference mention?
University of Florida
438
[ "relation", "to", "birth", "defects", "reinforce", "the", "broader", "conclusions", "from", "the", "scientific", "References", "literature.", "No", "convincing", "evidence", "exists", "1.", "Roberts,", "H.", "R.", "and", "J.", "J.", "Barone,", "that", "normal", "maternal", "caffeine", "consump-", "\"Biological", "Effects", "of", "Caffeine:", "tion", "is", "associated", "with", "increased", "risk", "of", "History", "and", "Use,\"", "Food", "Technology,", "human", "birth", "defects.", "37", "No.", "9,", "pp.", "32-39,", "1983.", "Caffeine", "and", "Other", "Alleged", "Health", "Related", "Effects", "At", "one", "time", "or", "another", "in", "recent", "years,", "caffeine", "has", "been", "alleged", "2.", "PepsiCo,", "Inc.,", "The", "Physical", "or", "to", "be", "connected", "with", "peptic", "ulcers,", "car-", "Technical", "Effect", "of", "Caffeine", "in", "Cola", "diovascular", "diseases,", "cancer,", "and", "Beverages,", "Purchase,", "N.Y.,", "July", "20,", "fibrocystic", "(benign)", "breast", "disease", "1981.", "However,", "extensive", "scientific", "research", "has", "failed", "to", "confirm", "such", "allegations.", "Some", "of", "these", "concerns", "were", "reviewed", "by", "the", "FASEB", "expert", "committee.", "More", "recently", "3.", "Institute", "of", "Food", "Technologists'", "the", "Expert", "Panel", "on", "Food", "Safety", "and", "Expert", "Panel", "on", "Food", "Safety", "and", "Nutrition", "convened", "by", "the", "Institute", "of", "Nutrition,", "\"Caffeine,\"", "Food", "Food", "Technologists", "also", "reviewed", "perti-", "Technology,", "37,", "No.", "4,", "pp.", "87-91,", "ment", "scientific", "studies", "regarding", "the", "1983.", "possible", "link", "between", "caffeine", "consump-", "tion", "and", "these", "health", "problems.", "The", "Panel", "concluded", "that", "the", "existing", "scien-", "4.", "American", "Council", "on", "Science", "and", "tific", "evidence", "did", "not", "establish", "that", "caf-", "Health,", "The", "Health", "Effects", "of", "Caf-", "feine", "caused", "any", "of", "these", "ills.", "In", "all", "cases,", "feine,", "New", "York,", "N.", "Y.,", "March", "they", "cited", "evidence", "to", "the", "contrary,", "and,", "1981.", "in", "some", "cases", "unequivocally", "concluded", "that", "caffeine", "was", "not", "responsible", "for", "the", "health", "effect", "in", "question.", "3", "5.", "Von", "Borstel,", "R.", "W.,", "\"Biological", "Effects", "of", "Caffeine:", "Metabolism,\"", "Food", "Technology,", "37,", "No.", "9,", "pp.", "40-43,", "1983.", "Conclusion", "A", "vast", "body", "of", "evidence", "exists", "which", "supports", "the", "conclusion", "that", "normal", "6.", "Neims,", "A.", "H.,", "The", "Comparative", "amounts", "of", "caffeine,", "especially", "the", "small", "Metabolism", "and", "Pharmacokinetics", "amounts", "found", "in", "some", "soft", "drinks,", "do", "of", "Caffeine", "in", "the", "Regulatory", "Con-", "not", "present", "a", "hazard", "to", "humans.", "text,", "University", "of", "Florida,", "July", "18,", "1981.", "More", "Information", "7.", "Neims,", "A.", "H.,", "and", "R.", "W.", "von", "Borstel,", "'Caffeine:", "Its", "Metabolism", "and", "For", "general", "information", "on", "caffeine", "and", "Biochemical", "Mechanisms", "of", "its", "use", "in", "soft", "drinks,", "please", "contact", "the", "National", "Soft", "Drink", "Association,", "1101", "Action,\"", "in", "Nutrition", "and", "the", "Brain,", "Vol.", "6,", "R.", "J.", "Wurtman", "and", "Sixteenth", "Street,", "N.W.,", "Washington,", "D.C.", "20036", "(202)", "463-6770.", "J.", "J.", "Wurtman,", "Eds.,", "Raven", "Press,", "N.Y.,", "1983", "Source:", "https://www.industrydocuments.ucsf.edu/docs/pkpj0226" ]
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Which year is mentioned in the first reference?
1983
426
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who is marketing director?
Robert l. goldsmith
446
[ "Docket", "No.", "78N-0158", "Food", "and", "Drug", "Administration", "Hearings", "on", "Food", "Labeling", "Washington,", "D.", "C.", "September", "27,", "1978", "Testimony", "of", "Agnes", "Molnar", "Nutritionist,", "Food", "Law", "Project", "Community", "Action", "for", "Legal", "Services", "335", "Broadway,", "NY", "10013", ".", ".." ]
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What is the docket No?
78N-0158
426
[ "Boxs'", "Life", "July", "28,", "1972", "271", "MADISON", "AVE.", "NEW", "YORK", "N.", "Y.", "10016", "212", "LE2-", "0985", "Michael", "F.", "Jacobson,", "Ph.", "D.", "Center", "for", "Science", "in", "the", "Public", "Interest", "1346", "Connecticut", "Avenue,", "N.", "W.", "Room", "812", "Washington,", "D.", "C.", "20036", "Dear", "Dr.", "Jacobson:", "Attached", "is", "a", "copy", "of", "the", "information", "on", "soft", "drinks", "produced", "by", "our", "Reader", "Panel", "studies.", "This", "should", "contain", "the", "information", "you", "require.", "Cordially,", "RLG:j1", "Robert", "L.", "Goldsmith", "Att.", "Marketing", "Director", "THE", "NATIONAL", "MAGAZINE", "FOR", "ALL", "BOYS", "PUBLISHED", "BY", "THE", "BOY", "SCOUTS", "OF", "AMERICA", "Source:", "https://www.industrydocuments.ucsf.edu/docs/Ihpj0226" ]
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who published the national magazine for all boys ?
the boy scouts of america
442
[ "Coca", "-", "Cola", "F", "January", "29,", "2016", "MFJ", "meeting", "with", "Sandy", "Douglas,", "Coca-cola", "Co.", "Arti", "Arora,", "Senior", "Director", "Regulatory", "&", "Policy.", "Caren", "Pasquale", "Seckler,", "VP", "social", "commitment", "Jim", "O'Hara,", "CSPI", "He", "said", "that", "Coke", "has", "a", "five-point", "overall", "strategy:", "Shaping", "choice", "Innovation", "Clear", "facts", "(labeling?)", "Market", "responsibly", "(no", "logos", "on", "toys,", "etc.)", "Leading", "engagement", "(ABA's", "commitment", "to", "cut", "calories", "by", "20%)", "His", "main", "point", "was", "to", "explain", "Coke's", "One", "Brand", "marketing", "strategy,", "which", "means", "including", "all", "brands", "in", "each", "ad.", "This", "includes", "significant", "packaging", "redesign,", "e.g.,", "changing", "Diet", "Coke", "from", "silver", "with", "red", "trim", "to", "Coke", "red", "with", "silver", "trim.", "Indicated", "that", "this", "was", "going", "to", "happen", "for", "Coke", "Zero", "as", "well", "which", "is", "now", "black", "with", "red", "trim.", "Says", "it's", "a", "big", "deal.", "We", "shall", "see.", "His", "main", "point", "also", "was", "that", "Coke", "aims", "to", "reduce", "added", "sugars.", "It", "is", "making", "a", "big", "push", "to", "increase", "sales", "of", "7.5-", "to", "8.5-oz", "cans", "and", "bottles.", "He", "says", "they", "are", "higher", "priced", "now", "because", "relatively", "few", "bottlers", "have", "the", "ability", "to", "produce", "them,", "so", "shipping", "and", "other", "distribution", "costs", "are", "high.", "Coke", "wants", "to", "reduce", "the", "price", "differential.", "This", "faces", "significant", "hurdle", "with", "retailers", "who", "have", "relied", "on", "cheap", "soda", "as", "\"loss", "leader\".", "He", "hoped", "that", "the", "industry", "and", "health", "advocates", "could", "cooperate", "to", "push", "the", "moderation", "theme.", "And", "by", "industry,", "he", "meant", "the", "entire", "food", "and", "beverage", "industry,", "including", "supermarkets", "and", "restaurants.", "(I", "should", "talk", "with", "Larry", "Soler", "and", "others", "about", "that.)", "Moderation,", "he", "said,", "also", "represents", "a", "significant", "change", "in", "a", "40-year-old", "business", "model", "where", "one", "and", "all", "were", "rewarded", "by", "increasing", "unit", "volume.", "Focus", "now", "is", "on", "generating", "revenue", "rather", "than", "volume.", "He", "said", "that", "in", "a", "recent", "period", "of", "time", "only", "one", "in", "four", "Americans", "had", "had", "a", "Coke.", "If", "that", "number", "can", "be", "hiked", "to", "one", "in", "two", "Americans,", "then", "theoretically", "that", "can", "bring", "down", "the", "per", "capita", "consumption", "but", "still", "drive", "revenue", "increase.", "20%", "reduction", "in", "the", "UK", "from", "2015", "to", "2020", "(here", "is", "it", "20%", "by", "2025):", "He", "said", "that", "Britons", "believe", "EFSA's", "reassurances", "that", "aspartame", "is", "safe,", "whereas", "Americans", "don't", "believe", "U.S.", "government", "assurances.", "Apparently,", "Britons", "have", "been", "switching", "from", "full-calorie", "to", "diet", "soft", "drinks.", "Source:", "https://www.industrydocuments.ucsf.edu/docs/gxpj0226" ]
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What is the date mentioned on the document?
January 29, 2016
446
[ "Docket", "No.", "78N-0158", "Food", "and", "Drug", "Administration", "Hearings", "on", "Food", "Labeling", "Washington,", "D.", "C.", "September", "27,", "1978", "Testimony", "of", "Agnes", "Molnar", "Nutritionist,", "Food", "Law", "Project", "Community", "Action", "for", "Legal", "Services", "335", "Broadway,", "NY", "10013", ".", ".." ]
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What is the date in document?
September 27, 1978
442
[ "Coca", "-", "Cola", "F", "January", "29,", "2016", "MFJ", "meeting", "with", "Sandy", "Douglas,", "Coca-cola", "Co.", "Arti", "Arora,", "Senior", "Director", "Regulatory", "&", "Policy.", "Caren", "Pasquale", "Seckler,", "VP", "social", "commitment", "Jim", "O'Hara,", "CSPI", "He", "said", "that", "Coke", "has", "a", "five-point", "overall", "strategy:", "Shaping", "choice", "Innovation", "Clear", "facts", "(labeling?)", "Market", "responsibly", "(no", "logos", "on", "toys,", "etc.)", "Leading", "engagement", "(ABA's", "commitment", "to", "cut", "calories", "by", "20%)", "His", "main", "point", "was", "to", "explain", "Coke's", "One", "Brand", "marketing", "strategy,", "which", "means", "including", "all", "brands", "in", "each", "ad.", "This", "includes", "significant", "packaging", "redesign,", "e.g.,", "changing", "Diet", "Coke", "from", "silver", "with", "red", "trim", "to", "Coke", "red", "with", "silver", "trim.", "Indicated", "that", "this", "was", "going", "to", "happen", "for", "Coke", "Zero", "as", "well", "which", "is", "now", "black", "with", "red", "trim.", "Says", "it's", "a", "big", "deal.", "We", "shall", "see.", "His", "main", "point", "also", "was", "that", "Coke", "aims", "to", "reduce", "added", "sugars.", "It", "is", "making", "a", "big", "push", "to", "increase", "sales", "of", "7.5-", "to", "8.5-oz", "cans", "and", "bottles.", "He", "says", "they", "are", "higher", "priced", "now", "because", "relatively", "few", "bottlers", "have", "the", "ability", "to", "produce", "them,", "so", "shipping", "and", "other", "distribution", "costs", "are", "high.", "Coke", "wants", "to", "reduce", "the", "price", "differential.", "This", "faces", "significant", "hurdle", "with", "retailers", "who", "have", "relied", "on", "cheap", "soda", "as", "\"loss", "leader\".", "He", "hoped", "that", "the", "industry", "and", "health", "advocates", "could", "cooperate", "to", "push", "the", "moderation", "theme.", "And", "by", "industry,", "he", "meant", "the", "entire", "food", "and", "beverage", "industry,", "including", "supermarkets", "and", "restaurants.", "(I", "should", "talk", "with", "Larry", "Soler", "and", "others", "about", "that.)", "Moderation,", "he", "said,", "also", "represents", "a", "significant", "change", "in", "a", "40-year-old", "business", "model", "where", "one", "and", "all", "were", "rewarded", "by", "increasing", "unit", "volume.", "Focus", "now", "is", "on", "generating", "revenue", "rather", "than", "volume.", "He", "said", "that", "in", "a", "recent", "period", "of", "time", "only", "one", "in", "four", "Americans", "had", "had", "a", "Coke.", "If", "that", "number", "can", "be", "hiked", "to", "one", "in", "two", "Americans,", "then", "theoretically", "that", "can", "bring", "down", "the", "per", "capita", "consumption", "but", "still", "drive", "revenue", "increase.", "20%", "reduction", "in", "the", "UK", "from", "2015", "to", "2020", "(here", "is", "it", "20%", "by", "2025):", "He", "said", "that", "Britons", "believe", "EFSA's", "reassurances", "that", "aspartame", "is", "safe,", "whereas", "Americans", "don't", "believe", "U.S.", "government", "assurances.", "Apparently,", "Britons", "have", "been", "switching", "from", "full-calorie", "to", "diet", "soft", "drinks.", "Source:", "https://www.industrydocuments.ucsf.edu/docs/gxpj0226" ]
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With whom is the meeting being conducted?
Sandy Douglas
444
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what is the title of the page?
historical background
442
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What is the date mentioned in the header of the document?
January 29, 2016
444
[ "Historical", "Background", "Caffeine", "is", "a", "widely-distributed,", "naturally-occurring", "substance", "found", "in", "more", "than", "60", "plant", "species", "throughout", "the", "world.", "Coffee", "beans,", "tea", "leaves,", "kola", "nuts,", "and", "cocoa", "beans", "are", "among", "the", "more", "common", "sources", "of", "caffeine", "con-", "sumed", "by", "humans.", "People", "the", "world", "over", "have", "enjoyed", "beverages", "made", "from", "these", "natural", "sources", "for", "thousands", "of", "years.", "Caffeine", "consumption", "dates", "back", "to", "prehistoric", "times.", "The", "first", "written", "men-", "tion", "of", "a", "caffeine-containing", "beverage,", "tea,", "is", "traditionally", "attributed", "to", "the", "legendary", "Chinese", "Emperor", "Shen", "Nung", "in", "2737", "B.C.", "Historians", "generally", "agree", "that", "coffee's", "consumption", "as", "a", "hot", "beverage", "dates", "from", "about", "1000", "A.D.", "and", "the", "coffee", "plant", "may", "have", "been", "cultivated", "in", "Ethiopia", "as", "early", "as", "575", "A.D.", "In", "1519,", "the", "Spanish", "Conquerors", "were", "treated", "to", "a", "sweetened", "chocolate", "drink", "by", "the", "Aztec", "Emperor", "Montezuma.", "Small", "amounts", "of", "caffeine", "have", "been", "used", "as", "a", "flavor", "component", "in", "cola", "and", "pepper", "soft", "drinks", "since", "they", "originated", "in", "the", "mid-1880's.1", "Caffeine", "in", "Soft", "Drinks", "Grocery", "shelves", "today", "offer", "a", "wide", "vari-", "ety", "of", "soft", "drinks,", "each", "one", "formulated", "to", "meet", "particular", "consumer", "taste", "preferences.", "Some", "soft", "drinks", "contain", "Source:", "https://www.industrydocuments.ucsf.edu/docs/pkpj0226" ]
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what are the common sources of caffeine consumed by humans?
coffee beans, tea leaves, kola nuts and cocoa beans
447
[ "The", "Coca", "Cola", "Company", "Media", "Relations", "Department", "news", "P.O.", "Drawer", "1734,", "Allanta,", "Ga.", "30301", "Telephone", "(404)", "676-2121", "release", "FOR", "IMMEDIATE", "RELEASE", "Contact", ":", "Carlton", "Curtis", "404/676-2678", "COCA-COLA", "BEGINS", "100TH", "YEAR", "WITH", "A", "NEW", "TASTE;", "FIRST", "CHANGE", "EVER", "IN", "SECRET", "FORMULA", "NEW", "YORK,", "April", "23,", "1985", "--", "Coca-cola,", "the", "world's", "number", "one", "consumer", "product,", "will", "begin", "its", "100th", "year", "with", "a", "new", "taste,", "representing", "the", "first", "change", "in", "the", "secret", "formula", "since", "Coca-cola", "was", "created", "in", "1886.", "\"The", "best", "has", "been", "made", "even", "better,\"", "said", "Roberto", "C.", "Goizueta,", "chairman", "of", "the", "Board", "and", "chief", "executive", "officer", "of", "The", "Coca-cola", "Company.", "\"We", "have", "changed", "the", "taste", "of", "the", "most", "universally", "enjoyed", "consumer", "product", "around", "the", "world.", "\"Consumers", "in", "blind", "taste", "tests", "all", "across", "the", "continent", "have", "told", "us", "they", "prefer", "the", "new", "taste", "of", "Coca-cola", "to", "the", "original", "by", "an", "overwhelming", "majority,", "\"", "Mr.", "Goizueta", "said,", "\"and", "there", "is", "an", "even", "wider", "margin", "when", "consumers", "are", "told,", "'This", "is", "a", "new", "Coca-cola.", "'\"", "Mr.", "Goizueta", "added,", "\"", "Some", "may", "choose", "to", "call", "this", "the", "boldest", "single", "marketing", "move", "in", "the", "history", "of", "the", "packaged", "goods", "business.", "We", "simply", "call", "it", "the", "surest", "move", "ever", "made,", "because", "the", "new", "taste", "of", "Coke", "was", "shaped", "by", "the", "taste", "of", "the", "consumer", ".", "Source:", "https://www.industrydocu?tents", "cuntents.ucsf.edu/docs/lzyj0226" ]
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What is the name of the person mentioned to Contact?
Carlton Curtis
447
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Which year is COCA-COLA beginning with a new taste?
100th year
447
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What is the date mentioned?
April 23, 1985
444
[ "Historical", "Background", "Caffeine", "is", "a", "widely-distributed,", "naturally-occurring", "substance", "found", "in", "more", "than", "60", "plant", "species", "throughout", "the", "world.", "Coffee", "beans,", "tea", "leaves,", "kola", "nuts,", "and", "cocoa", "beans", "are", "among", "the", "more", "common", "sources", "of", "caffeine", "con-", "sumed", "by", "humans.", "People", "the", "world", "over", "have", "enjoyed", "beverages", "made", "from", "these", "natural", "sources", "for", "thousands", "of", "years.", "Caffeine", "consumption", "dates", "back", "to", "prehistoric", "times.", "The", "first", "written", "men-", "tion", "of", "a", "caffeine-containing", "beverage,", "tea,", "is", "traditionally", "attributed", "to", "the", "legendary", "Chinese", "Emperor", "Shen", "Nung", "in", "2737", "B.C.", "Historians", "generally", "agree", "that", "coffee's", "consumption", "as", "a", "hot", "beverage", "dates", "from", "about", "1000", "A.D.", "and", "the", "coffee", "plant", "may", "have", "been", "cultivated", "in", "Ethiopia", "as", "early", "as", "575", "A.D.", "In", "1519,", "the", "Spanish", "Conquerors", "were", "treated", "to", "a", "sweetened", "chocolate", "drink", "by", "the", "Aztec", "Emperor", "Montezuma.", "Small", "amounts", "of", "caffeine", "have", "been", "used", "as", "a", "flavor", "component", "in", "cola", "and", "pepper", "soft", "drinks", "since", "they", "originated", "in", "the", "mid-1880's.1", "Caffeine", "in", "Soft", "Drinks", "Grocery", "shelves", "today", "offer", "a", "wide", "vari-", "ety", "of", "soft", "drinks,", "each", "one", "formulated", "to", "meet", "particular", "consumer", "taste", "preferences.", "Some", "soft", "drinks", "contain", "Source:", "https://www.industrydocuments.ucsf.edu/docs/pkpj0226" ]
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what is widely distributed naturally occuring substance found in more than 60 plant species throughout he world?
caffeine
447
[ "The", "Coca", "Cola", "Company", "Media", "Relations", "Department", "news", "P.O.", "Drawer", "1734,", "Allanta,", "Ga.", "30301", "Telephone", "(404)", "676-2121", "release", "FOR", "IMMEDIATE", "RELEASE", "Contact", ":", "Carlton", "Curtis", "404/676-2678", "COCA-COLA", "BEGINS", "100TH", "YEAR", "WITH", "A", "NEW", "TASTE;", "FIRST", "CHANGE", "EVER", "IN", "SECRET", "FORMULA", "NEW", "YORK,", "April", "23,", "1985", "--", "Coca-cola,", "the", "world's", "number", "one", "consumer", "product,", "will", "begin", "its", "100th", "year", "with", "a", "new", "taste,", "representing", "the", "first", "change", "in", "the", "secret", "formula", "since", "Coca-cola", "was", "created", "in", "1886.", "\"The", "best", "has", "been", "made", "even", "better,\"", "said", "Roberto", "C.", "Goizueta,", "chairman", "of", "the", "Board", "and", "chief", "executive", "officer", "of", "The", "Coca-cola", "Company.", "\"We", "have", "changed", "the", "taste", "of", "the", "most", "universally", "enjoyed", "consumer", "product", "around", "the", "world.", "\"Consumers", "in", "blind", "taste", "tests", "all", "across", "the", "continent", "have", "told", "us", "they", "prefer", "the", "new", "taste", "of", "Coca-cola", "to", "the", "original", "by", "an", "overwhelming", "majority,", "\"", "Mr.", "Goizueta", "said,", "\"and", "there", "is", "an", "even", "wider", "margin", "when", "consumers", "are", "told,", "'This", "is", "a", "new", "Coca-cola.", "'\"", "Mr.", "Goizueta", "added,", "\"", "Some", "may", "choose", "to", "call", "this", "the", "boldest", "single", "marketing", "move", "in", "the", "history", "of", "the", "packaged", "goods", "business.", "We", "simply", "call", "it", "the", "surest", "move", "ever", "made,", "because", "the", "new", "taste", "of", "Coke", "was", "shaped", "by", "the", "taste", "of", "the", "consumer", ".", "Source:", "https://www.industrydocu?tents", "cuntents.ucsf.edu/docs/lzyj0226" ]
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996 ], [ 497, 980, 772, 998 ] ]
Who said, "The best has been made even better"?
Roberto C. Goizueta, chairman of the Board and Chief executive officer of The Coca-Cola Company
448
[ "Coke", "Isit!", "news", "Coca", "Cola's", "Coker", "release", "COCA-COLA", "USA", "Public", "Relations", "Department", "P.O.", "Drawer", "1734.", "Atlanta.", "Ga.", "30301", "elephone", "(404)", "808-2121", "CONTACT:", "Tony", "Tortorici", "FOR", "IMMEDIATE", "RELEASE", "404/898-3696", "PAUSE", "TO", "REFLECT", "95", "YEARS", "OF", "ADVERTISING", "FOR", "COCA-COLA", "ATLANTA,", "Feb.", "4,", "1982", "--", "\"Coke", "is", "it!\"", "is", "the", "new", "advertising", "theme", "for", "Coca-cola", "and", "the", "descendant", "of", "a", "series", "of", "slogans", "which", "are", "as", "much", "a", "part", "of", "American", "life", "as", "Brand", "Coke", "itself.", "Unveiled", "this", "week", "at", "a", "Coca-cola", "USA", "Bottlers'", "meeting", "in", "Atlanta,", "\"Coke", "is", "it!\"", "is", "a", "bold", "concept", "which", "succeeds", "\"Have", "a", "Coke", "and", "a", "smile,", "\"", "the", "main", "advertising", "theme", "for", "the", "product", "since", "1979.", "The", "new", "theme", "breaks", "from", "tradition", "by", "placing", "more", "emphasis", "on", "the", "superiority", "of", "Coca-cola", "in", "taste,", "total", "refreshment", "and", "as", "thirst", "quencher.", "The", "direct,", "positive", "statement", "--", "\"Coke", "is", "it!\"", "--", "appeals", "to", "the", "forthright", "stance", "of", "Americans", "in", "the", "1980s.", "Throughout", "the", "history", "of", "Coca-cola,", "the", "Company's", "advertising", "has", "accurately", "reflected", "attitudes", "of", "the", "times,", "often", "anticipating", "changing", "lifestyles", "and", "the", "national", "temperament.", "Since", "1886,", "adver-", "tising", "for", "Coca-cola", "has", "portrayed", "fluctuations", "in", "social", "climate,", "structure,", "values", "and", "politics.", "AJT/RCW/1.", "19.9", "(more)", "Source:", "https://www.industrydocuments.ucsf.edu/docs/ztyj0226" ]
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H ow many years of advertising is mentioned?
95
448
[ "Coke", "Isit!", "news", "Coca", "Cola's", "Coker", "release", "COCA-COLA", "USA", "Public", "Relations", "Department", "P.O.", "Drawer", "1734.", "Atlanta.", "Ga.", "30301", "elephone", "(404)", "808-2121", "CONTACT:", "Tony", "Tortorici", "FOR", "IMMEDIATE", "RELEASE", "404/898-3696", "PAUSE", "TO", "REFLECT", "95", "YEARS", "OF", "ADVERTISING", "FOR", "COCA-COLA", "ATLANTA,", "Feb.", "4,", "1982", "--", "\"Coke", "is", "it!\"", "is", "the", "new", "advertising", "theme", "for", "Coca-cola", "and", "the", "descendant", "of", "a", "series", "of", "slogans", "which", "are", "as", "much", "a", "part", "of", "American", "life", "as", "Brand", "Coke", "itself.", "Unveiled", "this", "week", "at", "a", "Coca-cola", "USA", "Bottlers'", "meeting", "in", "Atlanta,", "\"Coke", "is", "it!\"", "is", "a", "bold", "concept", "which", "succeeds", "\"Have", "a", "Coke", "and", "a", "smile,", "\"", "the", "main", "advertising", "theme", "for", "the", "product", "since", "1979.", "The", "new", "theme", "breaks", "from", "tradition", "by", "placing", "more", "emphasis", "on", "the", "superiority", "of", "Coca-cola", "in", "taste,", "total", "refreshment", "and", "as", "thirst", "quencher.", "The", "direct,", "positive", "statement", "--", "\"Coke", "is", "it!\"", "--", "appeals", "to", "the", "forthright", "stance", "of", "Americans", "in", "the", "1980s.", "Throughout", "the", "history", "of", "Coca-cola,", "the", "Company's", "advertising", "has", "accurately", "reflected", "attitudes", "of", "the", "times,", "often", "anticipating", "changing", "lifestyles", "and", "the", "national", "temperament.", "Since", "1886,", "adver-", "tising", "for", "Coca-cola", "has", "portrayed", "fluctuations", "in", "social", "climate,", "structure,", "values", "and", "politics.", "AJT/RCW/1.", "19.9", "(more)", "Source:", "https://www.industrydocuments.ucsf.edu/docs/ztyj0226" ]
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What is the date mentioned?
Feb. 4, 1982
444
[ "Historical", "Background", "Caffeine", "is", "a", "widely-distributed,", "naturally-occurring", "substance", "found", "in", "more", "than", "60", "plant", "species", "throughout", "the", "world.", "Coffee", "beans,", "tea", "leaves,", "kola", "nuts,", "and", "cocoa", "beans", "are", "among", "the", "more", "common", "sources", "of", "caffeine", "con-", "sumed", "by", "humans.", "People", "the", "world", "over", "have", "enjoyed", "beverages", "made", "from", "these", "natural", "sources", "for", "thousands", "of", "years.", "Caffeine", "consumption", "dates", "back", "to", "prehistoric", "times.", "The", "first", "written", "men-", "tion", "of", "a", "caffeine-containing", "beverage,", "tea,", "is", "traditionally", "attributed", "to", "the", "legendary", "Chinese", "Emperor", "Shen", "Nung", "in", "2737", "B.C.", "Historians", "generally", "agree", "that", "coffee's", "consumption", "as", "a", "hot", "beverage", "dates", "from", "about", "1000", "A.D.", "and", "the", "coffee", "plant", "may", "have", "been", "cultivated", "in", "Ethiopia", "as", "early", "as", "575", "A.D.", "In", "1519,", "the", "Spanish", "Conquerors", "were", "treated", "to", "a", "sweetened", "chocolate", "drink", "by", "the", "Aztec", "Emperor", "Montezuma.", "Small", "amounts", "of", "caffeine", "have", "been", "used", "as", "a", "flavor", "component", "in", "cola", "and", "pepper", "soft", "drinks", "since", "they", "originated", "in", "the", "mid-1880's.1", "Caffeine", "in", "Soft", "Drinks", "Grocery", "shelves", "today", "offer", "a", "wide", "vari-", "ety", "of", "soft", "drinks,", "each", "one", "formulated", "to", "meet", "particular", "consumer", "taste", "preferences.", "Some", "soft", "drinks", "contain", "Source:", "https://www.industrydocuments.ucsf.edu/docs/pkpj0226" ]
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who is traditionally attributed to legendary for the first written mention of a coffee containing beverage tea?
Chinese emperor Shen nung
448
[ "Coke", "Isit!", "news", "Coca", "Cola's", "Coker", "release", "COCA-COLA", "USA", "Public", "Relations", "Department", "P.O.", "Drawer", "1734.", "Atlanta.", "Ga.", "30301", "elephone", "(404)", "808-2121", "CONTACT:", "Tony", "Tortorici", "FOR", "IMMEDIATE", "RELEASE", "404/898-3696", "PAUSE", "TO", "REFLECT", "95", "YEARS", "OF", "ADVERTISING", "FOR", "COCA-COLA", "ATLANTA,", "Feb.", "4,", "1982", "--", "\"Coke", "is", "it!\"", "is", "the", "new", "advertising", "theme", "for", "Coca-cola", "and", "the", "descendant", "of", "a", "series", "of", "slogans", "which", "are", "as", "much", "a", "part", "of", "American", "life", "as", "Brand", "Coke", "itself.", "Unveiled", "this", "week", "at", "a", "Coca-cola", "USA", "Bottlers'", "meeting", "in", "Atlanta,", "\"Coke", "is", "it!\"", "is", "a", "bold", "concept", "which", "succeeds", "\"Have", "a", "Coke", "and", "a", "smile,", "\"", "the", "main", "advertising", "theme", "for", "the", "product", "since", "1979.", "The", "new", "theme", "breaks", "from", "tradition", "by", "placing", "more", "emphasis", "on", "the", "superiority", "of", "Coca-cola", "in", "taste,", "total", "refreshment", "and", "as", "thirst", "quencher.", "The", "direct,", "positive", "statement", "--", "\"Coke", "is", "it!\"", "--", "appeals", "to", "the", "forthright", "stance", "of", "Americans", "in", "the", "1980s.", "Throughout", "the", "history", "of", "Coca-cola,", "the", "Company's", "advertising", "has", "accurately", "reflected", "attitudes", "of", "the", "times,", "often", "anticipating", "changing", "lifestyles", "and", "the", "national", "temperament.", "Since", "1886,", "adver-", "tising", "for", "Coca-cola", "has", "portrayed", "fluctuations", "in", "social", "climate,", "structure,", "values", "and", "politics.", "AJT/RCW/1.", "19.9", "(more)", "Source:", "https://www.industrydocuments.ucsf.edu/docs/ztyj0226" ]
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Whose name is mentioned to Contact?
Tony tortorici
454
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What is the heading of the document?
Response Document
454
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What are mixed with α, γ?
α, γ
454
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What are the renal effects mentioned?
urine electrolytes, osmolality, pH
444
[ "Historical", "Background", "Caffeine", "is", "a", "widely-distributed,", "naturally-occurring", "substance", "found", "in", "more", "than", "60", "plant", "species", "throughout", "the", "world.", "Coffee", "beans,", "tea", "leaves,", "kola", "nuts,", "and", "cocoa", "beans", "are", "among", "the", "more", "common", "sources", "of", "caffeine", "con-", "sumed", "by", "humans.", "People", "the", "world", "over", "have", "enjoyed", "beverages", "made", "from", "these", "natural", "sources", "for", "thousands", "of", "years.", "Caffeine", "consumption", "dates", "back", "to", "prehistoric", "times.", "The", "first", "written", "men-", "tion", "of", "a", "caffeine-containing", "beverage,", "tea,", "is", "traditionally", "attributed", "to", "the", "legendary", "Chinese", "Emperor", "Shen", "Nung", "in", "2737", "B.C.", "Historians", "generally", "agree", "that", "coffee's", "consumption", "as", "a", "hot", "beverage", "dates", "from", "about", "1000", "A.D.", "and", "the", "coffee", "plant", "may", "have", "been", "cultivated", "in", "Ethiopia", "as", "early", "as", "575", "A.D.", "In", "1519,", "the", "Spanish", "Conquerors", "were", "treated", "to", "a", "sweetened", "chocolate", "drink", "by", "the", "Aztec", "Emperor", "Montezuma.", "Small", "amounts", "of", "caffeine", "have", "been", "used", "as", "a", "flavor", "component", "in", "cola", "and", "pepper", "soft", "drinks", "since", "they", "originated", "in", "the", "mid-1880's.1", "Caffeine", "in", "Soft", "Drinks", "Grocery", "shelves", "today", "offer", "a", "wide", "vari-", "ety", "of", "soft", "drinks,", "each", "one", "formulated", "to", "meet", "particular", "consumer", "taste", "preferences.", "Some", "soft", "drinks", "contain", "Source:", "https://www.industrydocuments.ucsf.edu/docs/pkpj0226" ]
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who were treated to a sweetened chocolate drink by aztec emporer montezuma?
spanish conquerors
465
[ "From:", "Kanayama", "Kiyoshi/B", "=", "40", "#jAPE", "To:", "Spanheimer,", "Robert", "CC:", "Sent:", "Shepard,", "Kirk", "(TPI);", "Fuse,", "Touichirou", "(TPC)", "10/27/2011", "5:14:48", "PM", "Subject:", "Re:", "Potential", "Publication", "in", "Correspondence", "Section", "of", "The", "Lance", "Dear", "Bob,", "Thank", "you", "for", "your", "response.", "Best,", "Kiyoshi", "On", "2011/10/27,", "at", "22:07,", "\"Spanheimer,", "Robert\"", "<bob.spanheimer@takeda.com>", "wrote:", "Dear", "Kiyoshi", "As", "noted", "below", "several", "letters", "were", "written", "to", "Lancet", "and", "the", "journal", "requested", "a", "response", "from", "the", "Proactive", "steering", "committee.", "The", "timeline", "for", "the", "response", "was", "short,", "I", "believe", "4-5", "days,", "and", "was", "to", "come", "from", "the", "Proactive", "steering", "committee.", "Because", "of", "the", "short", "timeline,", "the", "Proactive", "steering", "committee", "was", "contacted", "as", "well", "as", "key", "members", "of", "the", "Actos", "publication", "team", "to", "determine", "if", "we", "should", "respond,", "and", "then", "draft", "a", "response.", "The", "decision", "was", "we", "must", "respond,", "and", "Erland_Erdmann(Chair", "of", "the", "committee)", "John", "Dormandy", "(lead", "author", "on", "the", "original", "publication),", "and", "Massimo", "Massi-Benedetti", "(safety", "officer", "of", "Proactive)", "and", "I", "wrote", "the", "response", "letter.", "The", "GMST", "for", "Actos", "as", "well", "as", "Alphonso", "Perez", "the", "GDT", "lead", "were", "informed.", "Bob", "--.", ".", ".", "..", "From:", "Kanayama", "Kiyoshi@takeda.co.jp", "[mailto:Kanayama_Kiyoshi@takeda.co.jp]", "Confidential", "-", "Subject", "to", "Protective", "Order", "TAK-SPANHR-00005674", "EXHIBIT", "(5", "DATE:", "/62", "22", "-13", "Juliana", "Zajicek", "CSR", "Source:", "https://www.indupsodoroooonts.ucsf.edu/docs/xtjf0226" ]
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From whom has this email been sent?
Kanayama Kiyoshi
465
[ "From:", "Kanayama", "Kiyoshi/B", "=", "40", "#jAPE", "To:", "Spanheimer,", "Robert", "CC:", "Sent:", "Shepard,", "Kirk", "(TPI);", "Fuse,", "Touichirou", "(TPC)", "10/27/2011", "5:14:48", "PM", "Subject:", "Re:", "Potential", "Publication", "in", "Correspondence", "Section", "of", "The", "Lance", "Dear", "Bob,", "Thank", "you", "for", "your", "response.", "Best,", "Kiyoshi", "On", "2011/10/27,", "at", "22:07,", "\"Spanheimer,", "Robert\"", "<bob.spanheimer@takeda.com>", "wrote:", "Dear", "Kiyoshi", "As", "noted", "below", "several", "letters", "were", "written", "to", "Lancet", "and", "the", "journal", "requested", "a", "response", "from", "the", "Proactive", "steering", "committee.", "The", "timeline", "for", "the", "response", "was", "short,", "I", "believe", "4-5", "days,", "and", "was", "to", "come", "from", "the", "Proactive", "steering", "committee.", "Because", "of", "the", "short", "timeline,", "the", "Proactive", "steering", "committee", "was", "contacted", "as", "well", "as", "key", "members", "of", "the", "Actos", "publication", "team", "to", "determine", "if", "we", "should", "respond,", "and", "then", "draft", "a", "response.", "The", "decision", "was", "we", "must", "respond,", "and", "Erland_Erdmann(Chair", "of", "the", "committee)", "John", "Dormandy", "(lead", "author", "on", "the", "original", "publication),", "and", "Massimo", "Massi-Benedetti", "(safety", "officer", "of", "Proactive)", "and", "I", "wrote", "the", "response", "letter.", "The", "GMST", "for", "Actos", "as", "well", "as", "Alphonso", "Perez", "the", "GDT", "lead", "were", "informed.", "Bob", "--.", ".", ".", "..", "From:", "Kanayama", "Kiyoshi@takeda.co.jp", "[mailto:Kanayama_Kiyoshi@takeda.co.jp]", "Confidential", "-", "Subject", "to", "Protective", "Order", "TAK-SPANHR-00005674", "EXHIBIT", "(5", "DATE:", "/62", "22", "-13", "Juliana", "Zajicek", "CSR", "Source:", "https://www.indupsodoroooonts.ucsf.edu/docs/xtjf0226" ]
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Who are on the CC list?
Shephard, Kirk (TPI); Fuse, Touichirou (TPC)
465
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What is the email ID of Kanayama Kiyoshi?
Kanayama_Kiyoshi@takeda.co.jp
465
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What is the subject of this email?
Re: Potential Publicaton in Correspondence Section of The Lancet
463
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What is the level of importance of the email send by Witte, Kimberly?
High
463
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What is the subject of the document?
fw: skb problems
463
[ "Nathaniel", "M", "Osbome", "08/06/99", "11:34", "AM", "Fo:", "Matthew", "W", "Beebe,", "Mitchell", "W", "Tull,", "Angela", "K", "Wade", "Subject:", "FW:", "SKB", "PROBLEMS", "fyi..nat", "-", "Forwarded", "by", "Nathaniel", "M", "Osbome/AM/LLY", "on", "08/06/99", "11:34", "AM", "----", "'Daly,", "Rich\"", "<rdaly", "@takedapharm.com>", "on", "08/06/99", "09:58:27", "AM", "To:", "\"Peters,", "Linda\"", "<LPeters", "cc:", "Nathaniel", "M", "Osborne,", "\"Orlando,", "Dan\"", "<dorlando,", "\"Blake,", "Bill\"", "<bblake", "V:", "SKB", "PROBLEMS", "Add", "this", "to", "the", "H&H", "conf", "call.", "ra", ">", ">", "From:", "---Original", "Message----\"", "Witte,", "Kimberly", "Sent", ":", ">", "To", ":", "Daly,", "Ric", "Friday,", "August", "06,", "1999", "9:26", "AM", "Cc:", "Graziano,", "Dave", ">", "Subject:", "PROBLEMS", ">", "Importance:", "High", ">", "Rich", "V", "V", "I", "am", "forwarding", "a", "message", "from", "Brian", "Chunn", "out", "of", "Champaign,", "IL.", "as", "though", "SKB", "is", "putting", "on", "some", "audio/teleconferences", "and", "giving", "out", "It", "seems", "incorrect", "information", "regarding", "Actos.", "The", "message", "from", "Brian", "is", ">", "self-explanatory.", "This", "is", "something", "that", "I", "wanted", "to", "bring", "to", "your", "attention", "to", "see", "if", "there", "is", "anything", "that", "we", "could", "do.", "I", "appreciate", "your", "VVVVVVVY", "attention", "to", "this", "as", "it", "is", "a", "big", "concern.", "call", "me", "if", "you", "have", "any", "questions.", "Thanks", "so", "much", "Rich!", "Please", "Kim", "Witte", "--Original", "Message--", "--", "VVVVVVVVVVY", "From:", "Chunn,", "Brian", "Sent", ":", "Thursday,", "August", "05,", "1999", "9:17", "PM", "To:", "Witte,", "Kimberly", "Subject:", "SKB", "PROBLEMS", "Hi", "Kim!", "I", "wanted", "to", "pass", "along", "a", "problem", "I", "came", "upon", "today", "while", "in", "Danville,", "IL.", "I", "was", "in", "Dr.", "Sadiq's", "office", "who", "is", "one", "of", "my", "big", "targets", "(9A)", "and", "we", "were", "discussing", "Actos.", "He", "proceeded", "to", "ask", "me", "if", "urinary", "bladder", "tumors", "were", "a", "problem", "with", "the", "FDA.", "(This", "is", "the", "Doctor", "who", "asked", "me", "a", "month", "ago", "if", ">", "Actos", "caused", "Urinary", "bladder", "cancer)", "Knowing", "this", "woulds", "come", "up", "I", "was", "prepared", "to", "discuss", "the", "portion", "of", "the", "PI", "on", "page", "9", "discussing", "tumors", ">", "found", "in", "rats,", "but", "no", "humans.", "When", "I", "asked", "where", "he", "had", "heard", "this", ">", "information,", "he", "proceeded", "to", "tell", "me", "it", "came", "from", "a", "Smith", "Kline", "Beecham", ">", "audio/tele", "conference.", "He", "mentioned", "the", "person", "he", "was", "discussing", "this", ">", "with", "mentioned", "that", "the", "tumors", "were", "why", "there", "was", "a", "delay", "in", "Actos", "coming", ">", "to", "market.", "I", "can't", "imagine", "this", "is", "fair", "balance.", "I", "am", "also", "running", "into", ">", "some", "smaller", "objections", "from", "Docs", "BEFORE", "I", "have", "even", "discussed", "Actos", "with", ">", "them.", "I'm", "not", "sure", "if", "these", "are", "also", "coming", "from", "SKB", "speakers", "or", "if", "it", ">", "is", "coming", "from", "the", "SKB", "reps", "locally.", "However,", "I", "do", "know", "the", "urinary", ">", "bladder", "tumor", "came", "from", "some", "form", "of", "an", "audio/tele", "conference", "from", "SKB.", "just", "need", "to", "find", "out", "if", "there", "is", "anything", "that", "can", "be", "done", "to", "stop", "their", "I", "PENGAD", "800-891-890", "EXHIBIT", "Confidential", "-", "Subject", "to", "Protective", "Order", "LLY-CRCARCH-00008577", "Beebe", "11.12.13", "Source:", "https://www.indup58gooooonts.ucsf.edu/docs/tsjf0226" ]
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What is the EXHIBIT number mentioned?
9
463
[ "Nathaniel", "M", "Osbome", "08/06/99", "11:34", "AM", "Fo:", "Matthew", "W", "Beebe,", "Mitchell", "W", "Tull,", "Angela", "K", "Wade", "Subject:", "FW:", "SKB", "PROBLEMS", "fyi..nat", "-", "Forwarded", "by", "Nathaniel", "M", "Osbome/AM/LLY", "on", "08/06/99", "11:34", "AM", "----", "'Daly,", "Rich\"", "<rdaly", "@takedapharm.com>", "on", "08/06/99", "09:58:27", "AM", "To:", "\"Peters,", "Linda\"", "<LPeters", "cc:", "Nathaniel", "M", "Osborne,", "\"Orlando,", "Dan\"", "<dorlando,", "\"Blake,", "Bill\"", "<bblake", "V:", "SKB", "PROBLEMS", "Add", "this", "to", "the", "H&H", "conf", "call.", "ra", ">", ">", "From:", "---Original", "Message----\"", "Witte,", "Kimberly", "Sent", ":", ">", "To", ":", "Daly,", "Ric", "Friday,", "August", "06,", "1999", "9:26", "AM", "Cc:", "Graziano,", "Dave", ">", "Subject:", "PROBLEMS", ">", "Importance:", "High", ">", "Rich", "V", "V", "I", "am", "forwarding", "a", "message", "from", "Brian", "Chunn", "out", "of", "Champaign,", "IL.", "as", "though", "SKB", "is", "putting", "on", "some", "audio/teleconferences", "and", "giving", "out", "It", "seems", "incorrect", "information", "regarding", "Actos.", "The", "message", "from", "Brian", "is", ">", "self-explanatory.", "This", "is", "something", "that", "I", "wanted", "to", "bring", "to", "your", "attention", "to", "see", "if", "there", "is", "anything", "that", "we", "could", "do.", "I", "appreciate", "your", "VVVVVVVY", "attention", "to", "this", "as", "it", "is", "a", "big", "concern.", "call", "me", "if", "you", "have", "any", "questions.", "Thanks", "so", "much", "Rich!", "Please", "Kim", "Witte", "--Original", "Message--", "--", "VVVVVVVVVVY", "From:", "Chunn,", "Brian", "Sent", ":", "Thursday,", "August", "05,", "1999", "9:17", "PM", "To:", "Witte,", "Kimberly", "Subject:", "SKB", "PROBLEMS", "Hi", "Kim!", "I", "wanted", "to", "pass", "along", "a", "problem", "I", "came", "upon", "today", "while", "in", "Danville,", "IL.", "I", "was", "in", "Dr.", "Sadiq's", "office", "who", "is", "one", "of", "my", "big", "targets", "(9A)", "and", "we", "were", "discussing", "Actos.", "He", "proceeded", "to", "ask", "me", "if", "urinary", "bladder", "tumors", "were", "a", "problem", "with", "the", "FDA.", "(This", "is", "the", "Doctor", "who", "asked", "me", "a", "month", "ago", "if", ">", "Actos", "caused", "Urinary", "bladder", "cancer)", "Knowing", "this", "woulds", "come", "up", "I", "was", "prepared", "to", "discuss", "the", "portion", "of", "the", "PI", "on", "page", "9", "discussing", "tumors", ">", "found", "in", "rats,", "but", "no", "humans.", "When", "I", "asked", "where", "he", "had", "heard", "this", ">", "information,", "he", "proceeded", "to", "tell", "me", "it", "came", "from", "a", "Smith", "Kline", "Beecham", ">", "audio/tele", "conference.", "He", "mentioned", "the", "person", "he", "was", "discussing", "this", ">", "with", "mentioned", "that", "the", "tumors", "were", "why", "there", "was", "a", "delay", "in", "Actos", "coming", ">", "to", "market.", "I", "can't", "imagine", "this", "is", "fair", "balance.", "I", "am", "also", "running", "into", ">", "some", "smaller", "objections", "from", "Docs", "BEFORE", "I", "have", "even", "discussed", "Actos", "with", ">", "them.", "I'm", "not", "sure", "if", "these", "are", "also", "coming", "from", "SKB", "speakers", "or", "if", "it", ">", "is", "coming", "from", "the", "SKB", "reps", "locally.", "However,", "I", "do", "know", "the", "urinary", ">", "bladder", "tumor", "came", "from", "some", "form", "of", "an", "audio/tele", "conference", "from", "SKB.", "just", "need", "to", "find", "out", "if", "there", "is", "anything", "that", "can", "be", "done", "to", "stop", "their", "I", "PENGAD", "800-891-890", "EXHIBIT", "Confidential", "-", "Subject", "to", "Protective", "Order", "LLY-CRCARCH-00008577", "Beebe", "11.12.13", "Source:", "https://www.indup58gooooonts.ucsf.edu/docs/tsjf0226" ]
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What is the exhibit no given in the document?
9
476
[ "Memo", "to:", "Distribution", "July", "19,", "2002", "Page", "2", "Action", "Steps:", ".", "Please", "interpret", "this", "directive", "in", "its", "broadest", "sense", "to", "prevent", "the", "deletion", "or", "destruction", "of", "any", "recorded", "information", "and", "data", "relating", "in", "any", "way", "to", "Actos.", ".", "Please", "take", "steps", "immediately", "to", "preserve", "such", "documents", "and", "data", "within", "your", "department.", ".", "Please", "distribute", "this", "memo", "to", "members", "of", "your", "group", "and", "advise", "them", "of", "the", "importance", "of", "following", "these", "instructions.", "*", "*", "*", "*", "*", "If", "you", "have", "any", "questions", "regarding", "the", "implementation", "of", "this", "directive,", "please", "contact", "me", "Marlene", "Chulas", "Marlene", "C.", "Dubas", "Confidential", "-", "Subject", "to", "Protective", "Order", "TAK-RIM30b6-00000654", "Source:", "https://www.indup", "5309-ooo02ts.ucsf.edu/docs/sqjf0226" ]
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Who is this Memo to?
distribution
476
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What is the date mentioned?
JULY 19, 2002
476
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Whose signature is present at the bottom?
MARLENE C. DUBAS
461
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who are in the cc?
johnston,Kendra; precurato-grubb, marti
470
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Who is the 23rd Addressee mentioned in the list?
Senior Vice President, Accounting Center
471
[ "Draft", "Agenda", "o", "Continental", "breakfast", "(8:00-9:00)", "o", "Introductions", "(9:00-9:10)", "o", "Purpose", "of", "meeting", "(9:10-9:15)", "o", "Generation", "of", "response", "to", "FDA", "(9:15-12:00)", "o", "Working", "lunch", "(12:00-1:00)", "o", "Discussion", "of", "proposed", "experiments:", "(12:00-1:00)", "o", "Feasibility", "o", "Study", "conduct", "o", "Timelines", "o", "Future", "plans", "(1:00-1:30)", "OS", "ponfidential", "-", "Subject", "to", "Protective", "Order", "TAK-BAROND-0000076", "Source:", "https://www.indup5379coo003ts.ucsf.edu/docs/xsjf0226" ]
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Heading of the document?
Draft Agenda
471
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What are the timings for Continental Breakfast?
8:00-9:00
461
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what is the "subject" of this letter?
article in today's USA Today regarding Avandia hearing
461
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who is writing this letter?
CHEN, GIGI
461
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when was this letter sent?
7/31/2007 11:48:09 AM
461
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who is the premier sales representative ?
gigi m. chen, MBA
481
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Heading of the document?
response document
483
[ "Takeda", "PENGAD", "800-431-698", "EXHIBIT", "40", "TO:", "Sam", "Hamanaka", "DATE:", "July", "19,", "2002", "Mark", "Booth", "Wendell", "Cheatham", "Rich", "Daly", "Terry", "Fukumoto", "Dean", "Hart", "Masatake", "Kashiyae", "Curtis", "Rhine", "Lori", "Smith", "Claire", "Thom", "Lee", "Voight", "Chuck", "Whitmer", "FROM:", "Marlene", "Dubas", "CC:", "Tom", "Muldoon", "RE:", "Preservation", "of", "Documents", "And", "Electronic", "Data", "relating", "to", "Actos", "MEMO:", "A", "motion", "has", "been", "filed", "to", "add", "Takeda", "Pharmaceuticals", "North", "America,", "Inc,", "and", "Takeda", "Pharmaceuticals", "America,", "Inc.", "as", "defendants", "in", "a", "lawsuit.", "The", "plaintiff", "in", "this", "lawsuit", "seeks", "damages", "for", "personal", "injury", "and", "wrongful", "death", "allegedly", "resulting", "from", "the", "use", "of", "certain", "prescription", "drugs,", "including", "Actos", "To", "be", "able", "to", "respond", "to", "discovery", "requests", "from", "the", "plaintiff,", "if", "that", "becomes", "necessary,", "we", "must", "take", "steps", "to", "preserve", "any", "documents", "that", "may", "be", "called", "for", "in", "this", "lawsuit.", "Until", "further", "notice,", "you", "are", "instructed", "to", "preserve", "any", "and", "all", "documents", "and", "electronic", "data", "which", "discuss,", "mention,", "or", "relate", "to", "Actos.", "This", "means", "do", "not", "destroy,", "delete,", "throw", "away", "or", "otherwise", "discard", "any", "such", "documents", "or", "electronic", "data.", "This", "includes", "correspondence,", "records,", "and", "data,", "contained", "in", "your", "paper", "and", "electronic", "files,", "regardless", "of", "form", "and", "including", "email", "correspondence", "and", "attachments", "and", "electronic", "data.", "Continued", ".", ".", ".", ".", "Confidential", "-", "Subject", "to", "Protective", "Order", "TAK-RIM30b6-00000653", "Source:", "https://www.indupt5309cooverits.ucsf.edu/docs/sqjf0226" ]
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who is writing this letter?
Marlene Dubas
483
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who is in the cc?
Tom Muldoon
483
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Which all compaies are added as defendants in a lawsuit?
Takeda Pharmaceuticals North America, Inc. and Takeda Pharmaceuticals America, Inc.
483
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what is 'RE' in the letter?
Preservation of Documents and Electronic Data relating to Actos
487
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855, 546, 873 ], [ 550, 855, 575, 873 ], [ 579, 855, 616, 874 ], [ 620, 855, 681, 874 ], [ 684, 855, 750, 874 ], [ 753, 855, 778, 874 ], [ 781, 855, 851, 874 ], [ 491, 922, 507, 931 ], [ 446, 965, 539, 980 ], [ 795, 956, 942, 970 ], [ 230, 980, 296, 997 ], [ 299, 980, 771, 997 ] ]
Heading of the first paragraph?
SIXTH OBJECTION
487
[ "SIXTH", "OBJECTION", "Takeda", "objects", "to", "the", "extent", "that", "the", "Interrogatory", "seeks", "information", "or", "material", "pertaining", "to", "alleged", "side", "effects", "or", "adverse", "reactions", "to", "Actos@", "other", "than", "those", "of", "the", "character", "allegedly", "experienced", "by", "plaintiffs", "on", "the", "ground", "that", "such", "information", "is", "not", "relevant", "to", "any", "claim", "or", "defense", "involved", "in", "this", "action.", "RESPONSE", "Supplemental", "Interrogatory", "No.", "2:", "During", "a", "July", "25,", "2013", "hearing", "before", "Judge", "Patrick", "Hanna", "counsel", "of", "Defendants", "advised", "the", "court", "that", "\"claims,", "settlements", "and", "litigation\"", "had", "been", "made", "during", "a", "timeframe", "as", "early", "as", "2002", "concerning", "personal", "injuries", "relating", "to", "Actos.", "For", "these", "claims,", "please", "provide:", "a.", "Date(s)", "of", "the", "personal", "injury", "claims", "made", "relating", "to", "Actos;", "b.", "Identity", "of", "party", "or", "parties", "bringing", "or", "making", "the", "personal", "injury", "claims;", "c.", "Location", "of", "where", "these", "personal", "injury", "claims", "were", "brought", "or", "made", "and", "which", "Takeda", "entities", "they", "were", "brought", "or", "made", "against", "d.", "Court", "or", "other", "authority", "or", "agency", "charged", "with", "adjudicationg", "these", "personal", "injury", "claims;", "e.", "Identity", "of", "the", "lawyers", "and", "law", "firms", "representing", "Takeda", "in", "these", "personal", "injury", "claims", "from", "inception", "to", "the", "present", "day;", "F.", "Date(s)", "of", "any", "litigation", "hold(s)", "put", "in", "place", "for", "these", "personal", "injury", "claims;", "g.", "Current", "status", "of", "these", "personal", "injury", "claims;", "h.", "If", "these", "claims", "have", "been", "resolved,", "how", "they", "were", "resolved;", "and", "i.", "If", "they", "were", "resolved,", "when", "were", "they", "resolved?", "Response:", "In", "addition", "to", "the", "General", "Objections,", "Takeda", "objects", "to", "Supplemental", "Interrogatory", "No.", "2,", "including", "all", "of", "its", "subparts,", "on", "the", "following", "grounds:", "(1)", "is", "overly", "broad", "and", "unduly", "burdensome;", "(2)", "it", "seeks", "information", "that", "is", "not", "relevant", "and", "not", "reasonably", "calculated", "to", "lead", "to", "the", "discovery", "of", "admissible", "evidence;", "(3)", "it", "is", "vague", "and/or", "ambiguous;", "and", "(4)", "it", "calls", "for", "the", "production", "of", "information", "protected", "from", "discovery", "by", "the", "work", "product", "doctrine,", "the", "attorney-", "w", "P7071-00004", "PLA-TAK-00061864", "Source:", "https://www.industrydocuments.ucsf.edu/docs/Izjf0226" ]
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855, 546, 873 ], [ 550, 855, 575, 873 ], [ 579, 855, 616, 874 ], [ 620, 855, 681, 874 ], [ 684, 855, 750, 874 ], [ 753, 855, 778, 874 ], [ 781, 855, 851, 874 ], [ 491, 922, 507, 931 ], [ 446, 965, 539, 980 ], [ 795, 956, 942, 970 ], [ 230, 980, 296, 997 ], [ 299, 980, 771, 997 ] ]
Name of the judge?
Patrick Hanna
487
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What is the page no mentioned in this document?
3
487
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When was the hearing before Judge?
July 25, 2013
501
[ "Dr.", "Tan", "January", "14,", "1999", "Page", "5", "ELI", "LILLY", "AND", "COMPANY", "COMPENSATION", "AND", "BENEFITS", "PROGRAM", "(CONTINUED)", "Additional", "Company", "Benefits", "Medical", "and", "Dental", "Insurance", "Prescription", "Drug", "Benefits", "Reimbursement", "Accounts", "Illness", "Pay", "Extended", "Disability", "(Eligibility", "begins", "after", "1", "year", "of", "service)", "Credit", "Union", "Moving", "Plan", "(see", "enclosed", "brochure)", "Retirement", "Plan", "Employee", "Health", "Services", "Employee", "Activities", "Educational", "Assistance", "Program", "Savings", "Plan", "Holiday", "and", "Vacation", "Plan", "Please", "refer", "to", "the", "\"Employee", "Compensation\"", "booklet", "for", "the", "details.", "Optional", "Employee-Paid", "Benefits", "Supplemental", "Life", "Insurance", "Dependent", "Life", "Insurance", "Flexible", "CarePlus", "(life/long-term", "care", "insurance)", "Confidential", "-", "Subject", "to", "Protective", "Order", "LLY-TANM-PF-00000050", "Source:", "https://www.indup6330-00005", "ts.ucsf.edu/docs/ttjf0226" ]
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What is the date mentioned?
January 14, 1999
503
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What is the name of the company mentioned in the letterhead?
DEPARTMENT OF HEALTH & HUMAN SERVICES
501
[ "Dr.", "Tan", "January", "14,", "1999", "Page", "5", "ELI", "LILLY", "AND", "COMPANY", "COMPENSATION", "AND", "BENEFITS", "PROGRAM", "(CONTINUED)", "Additional", "Company", "Benefits", "Medical", "and", "Dental", "Insurance", "Prescription", "Drug", "Benefits", "Reimbursement", "Accounts", "Illness", "Pay", "Extended", "Disability", "(Eligibility", "begins", "after", "1", "year", "of", "service)", "Credit", "Union", "Moving", "Plan", "(see", "enclosed", "brochure)", "Retirement", "Plan", "Employee", "Health", "Services", "Employee", "Activities", "Educational", "Assistance", "Program", "Savings", "Plan", "Holiday", "and", "Vacation", "Plan", "Please", "refer", "to", "the", "\"Employee", "Compensation\"", "booklet", "for", "the", "details.", "Optional", "Employee-Paid", "Benefits", "Supplemental", "Life", "Insurance", "Dependent", "Life", "Insurance", "Flexible", "CarePlus", "(life/long-term", "care", "insurance)", "Confidential", "-", "Subject", "to", "Protective", "Order", "LLY-TANM-PF-00000050", "Source:", "https://www.indup6330-00005", "ts.ucsf.edu/docs/ttjf0226" ]
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What is the company name ?
ELI LILLY AND COMPANY
503
[ "DEPARTMENT", "OF", "HEALTH", "&", "HUMAN", "SERVICES", "Public", "Health", "Service", "Food", "and", "Drug", "Administration", "Rockville,", "MD", "20857", "NDA", "21-073/S-026", "DISCIPLINE", "REVIEW", "LETTER", "Takeda", "Global", "Research", "&", "Development", "Center,", "Inc.", "RECEIVED", "Attention:", "Mary", "Jo", "Pritza,", "MPH,", "PharmD", "REGULATORY", "AFFAIRS", "DEPARTMENT", "Manager,", "Regulatory", "Affairs", "One", "Takeda", "Parkway", "Deerfield,", "IL", "60015", "FEB", "1", "9", "2007", "Dear", "Ms.", "Pritza:", "TAKEDA", "GLOBAL", "RESEARCH", "&", "DEVELOPMENT", "CENTER,", "ING", "Please", "refer", "to", "your", "January", "24,", "2006,", "supplemental", "new", "drug", "application", "(NDA)", "submitted", "under", "section", "505(b)", "of", "the", "Federal", "Food,", "Drug,", "and", "Cosmetic", "Act", "for", "Actos@", "(pioglitazone", "HCI)", "tablets,", "15", "mg,", "30", "mg,", "and", "45", "mg.", "We", "also", "refer", "to", "your", "submissions", "dated", "June", "1,", "August", "22", "and", "31,", "October", "10,", "November", "14,", "and", "December", "15,", "2006,", "and", "to", "our", "proposed", "labeling", "revisions", "sent", "to", "you", "(via", "e-mail)", "on", "February", "7,", "2007.", "Our", "review", "of", "the", "clinical", "section", "of", "your", "response", "to", "our", "labeling", "revisions", "is", "complete,", "and", "our", "summary", "of", "the", "rationale", "for", "our", "changes", "to", "your", "proposed", "label", "appear", "below.", "1.", "Movement", "of", "proposed", "information", "regarding", "outcome", "of", "the", "PROactive", "trial", "from", "the", "Clinical", "Studies", "section", "to", "the", "ADVERSE", "REACTIONS", "section,", "and", "inclusion", "of", "information", "only", "from", "the", "primary", "endpoint:", "This", "was", "a", "failed", "trial;", "statistical", "significance", "for", "the", "primary", "endpoint", "was", "not", "met,", "and", "the", "statistical", "evaluation", "does", "not", "support", "consideration", "of", "secondary", "endpoints", "in", "the", "event", "of", "failure", "to", "demonstrate", "significance", "for", "the", "primary", "endpoint.", "Even", "if", "you", "could", "demonstrate", "that", "it", "is", "statistically", "legitimate", "to", "consider", "secondary", "endpoints,", "the", "proposed", "\"main\"", "secondary", "endpoint", "was", "not", "placed", "in", "the", "statistical", "analysis", "plan", "until", "well", "after", "the", "trial", "had", "ended.", "Although", "technically", "it", "is", "possible", "to", "add", "new", "endpoints", "prior", "to", "breaking", "the", "blind,", "the", "long", "period", "of", "time", "(months)", "between", "study", "cessation", "and", "insertion", "of", "the", "new", "endpoint", "into", "the", "plan,", "the", "short", "period", "of", "time", "(days)", "between", "this", "addition", "and", "breaking", "of", "the", "blind,", "and", "the", "proposal", "to", "use", "this", "late-", "coming", "endpoint", "in", "the", "setting", "of", "a", "failed", "primary", "endpoint,", "give", "this", "endpoint", "the", "appearance", "of", "a", "post", "hoc", "analysis", "rather", "than", "a", "prospectively", "defined", "endpoint.", "Confidential", "-", "Subject", "to", "Protective", "Order", "TAK-PRITZM-00247931", "Produced", "in", "MDL", "on", "9/25/12", "Source:", "https://www.indusp0334..0000is.ucsf.edu/docs/kmjf0226" ]
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What is the fullform of NDA?
new drug application
502
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What is the date mentioned?
August 16, 1999
503
[ "DEPARTMENT", "OF", "HEALTH", "&", "HUMAN", "SERVICES", "Public", "Health", "Service", "Food", "and", "Drug", "Administration", "Rockville,", "MD", "20857", "NDA", "21-073/S-026", "DISCIPLINE", "REVIEW", "LETTER", "Takeda", "Global", "Research", "&", "Development", "Center,", "Inc.", "RECEIVED", "Attention:", "Mary", "Jo", "Pritza,", "MPH,", "PharmD", "REGULATORY", "AFFAIRS", "DEPARTMENT", "Manager,", "Regulatory", "Affairs", "One", "Takeda", "Parkway", "Deerfield,", "IL", "60015", "FEB", "1", "9", "2007", "Dear", "Ms.", "Pritza:", "TAKEDA", "GLOBAL", "RESEARCH", "&", "DEVELOPMENT", "CENTER,", "ING", "Please", "refer", "to", "your", "January", "24,", "2006,", "supplemental", "new", "drug", "application", "(NDA)", "submitted", "under", "section", "505(b)", "of", "the", "Federal", "Food,", "Drug,", "and", "Cosmetic", "Act", "for", "Actos@", "(pioglitazone", "HCI)", "tablets,", "15", "mg,", "30", "mg,", "and", "45", "mg.", "We", "also", "refer", "to", "your", "submissions", "dated", "June", "1,", "August", "22", "and", "31,", "October", "10,", "November", "14,", "and", "December", "15,", "2006,", "and", "to", "our", "proposed", "labeling", "revisions", "sent", "to", "you", "(via", "e-mail)", "on", "February", "7,", "2007.", "Our", "review", "of", "the", "clinical", "section", "of", "your", "response", "to", "our", "labeling", "revisions", "is", "complete,", "and", "our", "summary", "of", "the", "rationale", "for", "our", "changes", "to", "your", "proposed", "label", "appear", "below.", "1.", "Movement", "of", "proposed", "information", "regarding", "outcome", "of", "the", "PROactive", "trial", "from", "the", "Clinical", "Studies", "section", "to", "the", "ADVERSE", "REACTIONS", "section,", "and", "inclusion", "of", "information", "only", "from", "the", "primary", "endpoint:", "This", "was", "a", "failed", "trial;", "statistical", "significance", "for", "the", "primary", "endpoint", "was", "not", "met,", "and", "the", "statistical", "evaluation", "does", "not", "support", "consideration", "of", "secondary", "endpoints", "in", "the", "event", "of", "failure", "to", "demonstrate", "significance", "for", "the", "primary", "endpoint.", "Even", "if", "you", "could", "demonstrate", "that", "it", "is", "statistically", "legitimate", "to", "consider", "secondary", "endpoints,", "the", "proposed", "\"main\"", "secondary", "endpoint", "was", "not", "placed", "in", "the", "statistical", "analysis", "plan", "until", "well", "after", "the", "trial", "had", "ended.", "Although", "technically", "it", "is", "possible", "to", "add", "new", "endpoints", "prior", "to", "breaking", "the", "blind,", "the", "long", "period", "of", "time", "(months)", "between", "study", "cessation", "and", "insertion", "of", "the", "new", "endpoint", "into", "the", "plan,", "the", "short", "period", "of", "time", "(days)", "between", "this", "addition", "and", "breaking", "of", "the", "blind,", "and", "the", "proposal", "to", "use", "this", "late-", "coming", "endpoint", "in", "the", "setting", "of", "a", "failed", "primary", "endpoint,", "give", "this", "endpoint", "the", "appearance", "of", "a", "post", "hoc", "analysis", "rather", "than", "a", "prospectively", "defined", "endpoint.", "Confidential", "-", "Subject", "to", "Protective", "Order", "TAK-PRITZM-00247931", "Produced", "in", "MDL", "on", "9/25/12", "Source:", "https://www.indusp0334..0000is.ucsf.edu/docs/kmjf0226" ]
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What is the name of the addressee?
Ms. Pritza
502
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To whom is this letter addressed?
Alan D. Mackenzie
502
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What is the full form of TPA?
Takeda Pharmaceuticals America, Inc.