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PROBLEMS OF ENSURING THE COMPETITIVENESS OF ENTREPRENEURIAL STRUCTURES IN AGRICULTURAL SECTOR In this article, the issues of integration the entrepreneurial structures in the sphere of agricultural business are described. It is determined that integration of activity of structures this type leads to increase of own competitiveness of entrepreneurial structures at the same time with competitiveness growth of «nearest competitor ». The problems of state regulation of integration process development in agricultural sector of economy are touched.

An open-label multicenter observational study of the efficacy, tolerability, and safety of the nonsteroidal anti-inflammatory drug amtolmetin guacil in patients with knee osteoarthritis and dyspepsia Objective: to investigate the efficacy and tolerability of amtolmetin guacil (AMG; Niselat®, Dr. Reddy's Laboratories Ltd, India) versus previous therapy with nonsteroidal anti-inflammatory drugs (NSAIDs) in patients with knee osteoarthritis (OA) and signs of dyspepsia. Subjects and methods. The open-label observational study included 220 patients aged 30-65 years who suffered from knee OA and intense pain during NSAID intake and had symptoms of dyspepsia in the absence of contraindications to the use of AMG. Among the comorbidities that generally occurred in 68% of the patients, there was a preponderance of hypertension (42%), lower extremity varicose veins (6.4%), and diabetes mellitus (6%). Treatment efficacy was evaluated using three domains of the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), by also taking into account pain intensity and general health assessment on the visual analogue scale. A Severity of Dyspepsia Assessment (SODA) scale was used to rate dyspepsia. Results and discussion. AMG had a marked analgesic effect confirmed by 40% or more pain reduction that occurred in 72.5% of the patients. The high analgesic effect of AMG was confirmed by a statistically significant (p <0.001) reduction in the WOMAC index (pain and stiffness) and by an increase in functional activity. There was a significant decrease in painless and painful signs of dyspepsia, as well as positive changes in the measures “overall assessment of dyspepsia severity” (p < 0.001) and “satisfaction with treatment”. Overall assessment of AMG tolerability was only positive: excellent (33%), good (56%), and satisfactory (11%). There were no serious adverse events (AE). AE were graded as moderate and mild in 8 and 82% of cases, respectively. AE were recorded in 7.7% of the patients.

SEARCH OF A MINIMUM CUT OF THE NETWORK SCHEDULE BY MERGING VERTICES The essence of determining the minimum cut of the network model by merging vertices (edge tightening) of the critical network is presented. Examples of calculation of local minimum of the critical sections of the network using this method and a global minimum cut. It is found that the correctness of determining the global minimum cut significantly depends on the selected sequence of merging vertices. Implementation of the proposed approaches will allow to determining the operation to be optimized, calculate the amount of shortening and the number of resources involved.

Assessment of the level of fibrosising factors in patients with coronary heart disease and chronic kidney disease Objective: to study the level of fibrosing factor in patients with coronary heart disease and chronic kidney disease.Materials and methods: the study included 115 patients, mean age was 67.56 ± 12.42 years (63 men and 52 women) with ischemic heart disease (CAD), stable angina (tension), functional class 1-3, chronic kidney disease (CKD) C1-C4. The level of serum fibroblast growth factor 23 (FGF 23) was assessed using a multimatrix enzyme immunoassay for the quantitative determination of FGF 23 (Biomedica FGF 23).Results: in patients with CAD and CKD, the level of serum FGF23 progressively increases as the stage of CKD worsens and can be regarded as an early marker of CKD progression in patients with CAD. When studying the correlation between the level of serum FGF 23 and clinical and laboratory data, it was found that there is a correlation between FGF 23 and age, creatinine, urea, glomerular filtration rate.Conclusion: in patients with CAD and CKD, it is advisable to use the determination of the level of fibrosis factors to identify patients with a high risk of cardiovascular complications.

The mortality from external causes in individuals of risk group The article deals with the problem of mortality from external causes among the officers of the penitentiary system of the Russian Federation, who by virtue of their official duties, are in high-risk situations. The purpose of the analysis was to identify specific features and identify the main determinants of suicides and circumstances that led to the death of the officers of the penitentiary system in 2017 with the subsequent development of recommendations for optimizing the prevention of these adverse events. Such a study was conducted for the first time among the staff of the penitentiary system. Analysis of investigation materials on the deaths of officers from external causes shows that the level of suicide of officer was 0.12‰, the death rate of officers from external causes - 0.32‰. A generalized portrait of an officer of the penitentiary system committed suicide in 2017 is a 31-35 year old man who is serving in security or security units with a length of service of 1 to 5 years, with an average professional or a higher education, married, having children, positively characterized in the service, without penalties, non-conflict, organized, disciplined, not registered with a psychologist, not acting on his own initiative for help to a psychologist who has family problems, which he does not report was 0.32‰. A generalized portrait of the officer of the penitentiary system, who perished in 2017, was established. He is a 35-year-old man who is classified as a junior commander, serving as a junior inspector of the department (regime, guard), with service for about 8 years, who perished in August-September. It is concluded that it is possible to reduce the number of officers who died from external causes through measures of prevention proposed by the authors of this article.

COMPOSER AS AN AUTHOROLOGICAL FIGURE OF CREATIVE STRATEGIES OF SELF-REPRESENTATION: METHODOLOGICAL FOUNDATIONS The author's problem is very relevant in the humanities and musicology in particular. To analyze the phenomenon of auto-presentation in this work interdisciplinary methodology is involved. The author-composer actualizes communicative and auto-communicative strategies of self-presentation. Distinctive features of the strategy of auto-presentation are realized due to the ability of the musical author to represent his/her own musical creativity, as well as a system of views, ideas, self-descriptions.

Investigation on hyseresis influence of defection at magnetographic control on type of signal on magnetic tape Dependence of a kind of the signals caused by defects in ferromagnetic objects, on character of preliminary preparation of a magnetic tape, type of defect, its depth and features of magnetization of object is investigated at the control. Conditions at which there is a change of polarity of the signal caused by defect are established, at record of fields of defects on a magnetic tape, preliminary magnetized not before saturation and before saturation.

Surgical Treatment of Diuretic Resistant Ascites in Patients with Portal Hypertension 222 patients, who underwent surgery because of resistant ascitis are observed. 197 subjects had liver cirrhosis, 22 had Badd-Chiari syndrome and 2 had extrahepatic portal hypertension. There were 21 portocaval shunting, 69 lymphovenous shunting, 108 peritoneovenous shunting and 24 ductolysis performed. Good results (significant decrease of ascitis), satisfactory results (reduce of diuretic dosage) and unsatisfactory (no effect) were in 85, 55 and 82 cases respectively. After operation mortality was 9.9% (22 patients). Surgical treatment of resistant ascitis authors describe as efficient enough and indicate for some groups of patients with portal hypertension.

Principles of plants genofund maintenance, their dependence on bioecological properties of plant varieties The need to study plants population in order to choose methods for their genefunds maintenance and rational use of genetic resources is substantiated. To realise this task the following plant varieties have been used in the study: meadowrue Thalictrum simplex L., meadowrue minor Thalictrum minus L., savin Juniperus sabina L., and Licorice Korzhinsky - Glycyrrhiza korzhinsky Grig. Genetic diversity characteristics and differenciation of the objects under study have been carried out using isoferments as genetic markers.

ECOLOGICAL TEST OF PROMISING LINES OF BARLEY Evaluation of adaptability and character stability has an important place in plant breeding. The results of ecological test of 5 productive lines created atV.V. Dokuchaev Scientific Research Institute of Agriculture of the Central Black Earth Regionare presented. Researches were conducted in 4 different on edaphoclimatic conditions localities of the Central Black Earth Zone: Kamennaya Steppe and Mitrofanovka (Voronezh region), Tambov and Kursk.In competitive variety trial in the conditions of Kamennaya Steppe these lines had higher yield capacity in comparison with the productive standards. High plasticity and ultra stability were shown by lines 4/16 and 29/16. During two years of ecological study, growing conditions were rather contrasting - the environment indicator varied from 20.73 to 17.95.In 2017, the lines 40/16 and 41/16 showed weak drought resistancein the conditions of Mitrofanovka. These lines are of the intensive type, have the high crop capacity and will be used as base lines.The high-yield line 29/16 was the best in terms of the level of stability to stress conditions and degree of ecological adaptation. The lines 29/16 and 33/16 are going to be presented for the State variety trial by the indexes of the yield capacity and adaptability.

COMPUTER SIMULATION OF CASTING AND SOLIDIFICATION PROCESSES OF STANDARD CAST SAMPLES OF GREY CAST IRON For standard tension samples of gray cast iron, the possibility of using computer modeling to study factors affecting the morphology of dendritic crystals and the volumetric arrangement of defects of shrinkage origin is shown.

Awareness of patients of dermatovenerological institutions for prevention and treatment of syphilis The article presents the results of a survey of patients of dermatovenerological institutions of Moscow. Analyzes their views on syphilis as a medical-social problem. The characteristic views of respondents about prevention, possible ways of infection and the relationship to the self-treatment of syphilitic infection are described. Provides data about the negative consequences of untreated syphilis in the opinion of the respondents.

Institution's operation features exerting influence on econonmic analysis of their operation effective strength Currently, the results of the budget sector reform of the RF economy are assuming more and more distinctive shape resulting in forming a system of institutions of three basic types: fiscal, autonomous and budget ones. In spite of the several years-long period of the reform implementation, there are still no universal methodological formulations that allow to determine priorities of structural reforming: to identify the types of economic activities involving prioritized functioning of autonomous institutions, to estimate the practicality of fiscal institutions functioning. Publications of various authors, devoted to comparative characteristic of different types of institutions, give their comparisons beyond any connection with such a crucial function as economic analysis. As a result, currently, while stating the fact of existing considerable differences between institutions of three types, the methodology of institution operation analysis in the budget sector of the economy is developed in in its entirety (without reference to the type of institution), which presents a fundamental defect of the statements to be worked out. The article makes an attempt of a complex comparative analysis focusing its attention on the way how the identified functioning features of the institutions of the three types can exert their influence on economic analysis of their operation.

Event-driven approach to the development of network resources of educational institutions for young people and adults The article deals with the essence and principles of implementing event-driven approach as a tool of network resources development in organization of education for young people and adults. It is shown that the event-driven approach allows to resolve the contradictions in the development of the network resources of the educational process

METHOD OF ENDOVASCULAR INHIBITION OF LOCALLY ADVANCED BREAST CANCER NEOVASCULARIZATION Locally advanced breast cancer (LA BC) is one of the most hypervascular cancers of high angiogenic potential. It is identifiable by angiographic examination, which allows choosing the optimal ways of delivering cytostatics for targeted intraarterial chemotherapy.

The dating of Appearance of the icon of Mother of God Zhirovichskaja and of the beginning of church and monastic life in Zhirovichi in historical works of the 19-20 Centuries The article concerns on the process of the development of representations on the dating of appearance of the icon of Mother of God called Zhirovichskaja, and on the beginning of church and monastic life in Zhirovichi in historical literature of 19-20 centuries. The study shows that there is no consensus on this issue in the historiography of the studied period. Considerable attention is paid to the critical analysis of the concept of dating the appearence of the Zhirovichi icon by Ignatius Stebelsky and the reception of his hypothesis in later historiography.

Budgetary risk of a mistake A budget plan development is attended by the need for a big risk assessment. Alongside economic, political, and social risks there is a risk of a mistake. The latter needs to be considered as an independent attribute of the process of budget planning. For this purpose, the article gives the analysis of budgetary mistakes according to the criteria of the World Risk Society introduced by Ulrich Beck. The compliance of the criteria is proved. The budgetary risk of a mistake can arise in any place regardless of a particular geographical spot. It appears impossible to measure a risk and its consequences based on one, however well systematized, concept of risks. Nor is it possible to get the mistakes adequately recompensated. The author presents the classificationof budgetary mistakes according to the extent of formalization, scale, origin, localization, dependency, time, and impact on the final result.

ХFEATURES OF REALIZATION OF INNOVATIVE PROCESS AT THE INDUSTRIAL ENTERPRISES Theoretical bases and the basic components of innovative process are considered, the scheme of realization of innovative process at the industrial enterprise is offered

RECORDS REVISION OF RADULODON ERIKSSONII AND RADULOMYCES COPELANDII IN LENINGRAD REGION AND ST. PETERSBURG The material on rare species Radulodon erikssonii (Meruliaceae) and Radulomyces (Radulodon) copelandii (Pterulaceae) was studied. It was shown that previous records of Radulodon erikssonii for the Leningrad Region really belongs to Radulomyces copelandii, whereas Radulodon erikssonii is presented by single specimen, which corresponds only partly to the concept of the species in question. Both species are morphologically characterized and each description is provided by original photos of basidiome macro- and microstructure.

On Types of Anthropocentric Elements in Semantics of Discursive Words (by Material of French and Russian Languages) The article is devoted to the analysis of the elements of meaning with the semantic sign of ‘man' (anthropocentric elements) on the material of the Russian and French languages. Their role in the semantics of formal tokens and discursive words is discussed. The classification of a number of hidden anthropocentric elements is proposed, substantiation of this classification is given. Novelty of research consists in that such elements are related not only to a speaker and an observer, as in many works on similar topic, but to a carrier of a point of view, norm, a scale controller. The results of the additions of modern service descriptions and discursive words are presented. The author notes that the existing descriptions of the semantics for indicating an implicit presence of the element man use the impersonal construction or indicate the internal state of one of the main semantic actants (X wants, X believes that, X is experiencing the condition Y), or introduce the indicators of logical, emotional, probabilistic assessment, that is individualized figure behind the scenes is explicitly absent. It is proposed to include in the semantic description various types of anthropocentric elements of the hidden plan instead of combining them under the names of a speaker or an observer .

INFORMATION SUPPORT OF INDEPENDENT TRAVEL PLANNING Independent tourism - a tourist trip, committed c full or partial waiver of the services of tour opera-tors and travel agents. In organizing this type of tourism route developed independently and ac-quire the necessary services (travel, accommodation, meals, excursions, etc.). Independent tourism is becoming popular and promising that promotes the development of Internet resources to provide information support to tourism: online booking, e-tickets, tourist portals, forums. Conducted a sur-vey of a group of tourists of all ages in order to identify the preferences of the organization of the tour. The article also lists the most popular, according to travelers, Internet sites for the implemen-tation of self-tourism.

Translation of abbreviations of business discourse in Russian: cognitive approach The paper considers the role of cognitive science in creating the theory of abbreviation. The author attempts to justify the idea that nomination in the form of abbreviations proceeds in accordance with the laws of dialectics from the standpoint of cognitive science. Language, which is physiological in nature, is a material object, and its development is contradictory. On the one hand, all elements and levels of the language are in a state of functional unity and balance, on the other, internal contradictions are the source of transformations and changes . In the presence of this interaction, the impetus for the development of the language is laid. .In linguistics, the dialectic of development is explained by the existence of antinomies. Using several abbreviations as examples from the sublanguage of business communication, the author considers the antinomy of the “speaker and listener” (or between the sender and the recipient). When abbreviations occur, this antinomy is resolved in favor of the sender due to the law of speech economy. because the law of saving efforts applies. which is manifested in the rational use of speech tools in the process of communication. As for the Addressee, it is in their interest to get information in an easy to understand way, so most abbreviations, except for those assimilated in Russian, are given in brackets after the motivating word or phrase.

Demographic factor in the formation of the Russian labor market Subject. I investigate the current situation in the labor market, and factors affecting its formation and development. Objectives. The article aims to analyze the current demographic situation in Russia based on official statistical sources and expert opinions, to identify demographic problems and their impact on the current condition of the labor market and the structure of the economically active population over the next decade. Methods. The study employs the methods of logical, statistical, qualitative and qualitative analysis. Results. I offer an approach to further development of the mechanism of State regulation of demographic changes from the perspective of supporting the labor market with required labor. Conclusions. The demographic factor should be the basis of the policy of the State in the labor market. It is important to solve the issue of labor resource allocation on the territory of the country in accordance with plans for socioeconomic development. Trends in the labor market formation and development are primarily based on labor resources, the imbalance of their quality in territories. Thus, a differentiated approach to developing a labor market strategy with a long-term perspective is required.

The Role of Russian Orthodoxy in the Development of Social Responsibility of Small Business In contemporary Russia one can observe a number of phenomena, which over time may initiate a new historical cycle of economic development based on Orthodox ethics. The author believes that in today's Russia already exist socio-economic and religious and cultural opportunities for the formation of social responsibility, entrepreneurship on the basis of orthodox values.

SUPER APP AS ECOSYSTEM INTEGRATED TECHNOLOGY PLATFORM The article discusses the digital technological solutions to support the functioning of modern large ecosystems - superapplications (Super App). The implementation of a super application in the ecosystem as an integrator of mini-applications is justified technologically and organizationally in order to increase the loyal audience of users. The results of the analysis of the implementation of super-applications in Russia and the world are presented, as well as an assessment of the possibility of using the metrics of "lifetime value " to assess the effectiveness of super-applications in ecosystems.

SYSTEM-PSYCHOLOGICAL ANALYSIS OF THE POEM BY S. YESENIN "THE BLACK MAN" In this article the system-psychological analysis of one of the known poem by S.A. Yesenin is discussed from the positions of the interdisciplinary approach.

INSTITUTIONALIZATION OF CIVIL CONTROL IN THE RUSSIAN POLITICAL PROCESS (ON THE EXAMPLE OF THE VOLGOGRAD REGION) The objective of the research is to prove features of civil control realization in modern political process (on the example of Volgograd region) on the basis of the analysis of stages of its institutionalization in modern Russia. The tasks of the research are to operationalize “civil control”, to designate stages of the civil control institute formation at the federal and regional levels in the Russian Federation, to interpret the features of civil control realization in the modern political process in Volgograd region. The methodological bases of the research are western neoinstitutional developments (J. March and Y. Olsen’s standard neoinstitutionalism) allowing to reveal the interrelation between the formal norms and the informal rules while civil control being realized. Besides, they enable us to define the ways of interaction between public authorities and the society.

Admission of COVID-19 Reconvalescent under the Age of 18 to Participate in Sports The article is devoted to the problem of admission of children and adolescents who are COVID-19 reconvalescents to physical training and sports. The author substantiates the necessity of obligatory medical monitoring of children and adolescents at the stages of recovery after COVID-19, emphasizes the assessment of cardiovascular risks. He points out the importance of using functional diagnostic methods at the stage of recuperation. The article presents foreign approaches to cardiac risk assessment (experts of the American Heart Association), as well as the British algorithm of adaptation to physical activity. The article presents an algorithm for selecting the scheme of return to physical activity depending on the severity of the suffered COVID-19. The author summarizes domestic normative documentation in the issues of admission of COVID-19 reconvalescents to physical training and sports activities.

MARKETING IN HEALTH CARE AND PROBLEMS OF THE ORGANIZATION OF GERIATRIC SERVICE. Need and urgency of a subject of research is caused by significant increase in specific weight of persons of advanced and senile age in society in comparison with young. All patients for reliability of research were divided into 4 groups. The data received at studying of features of statement of tasks and the purposes in establishments of different forms of ownership testify that in all studied groups the purpose of rendering of medical care to persons as average, and advanced age coincide - improvement of medical social indicators of health and ensuring quality of medical care. But despite statement of a common aim and coincidence of the majority of tasks for achievement of the purpose, there are distinctions in ways of achievement this aim depending on age of patients and form of ownership of treatment-and-prophylactic establishment that causes a different results. It speaks features in planning of activity of the public and private institutions, especially in planning of factorial loading and preventive activity. The analysis of data shows that concerning all groups medical and diagnostic activity authentically prevailed over the preventive. When studying a place of the geriatric help in the market of medical services this segment is unattractive in respect of production mission of the health care, connected by that positive medical and economic effect is shown not at once, and after a while. In the carried-out researches by authors approaches to regulation of demand and offers in the market of medical services which are offered patients of advanced and senile age are formulated and recommendations about rendering of medical care of this category of patients, formation of uniform system of medical and rehabilitation actions at regional level with the mixed way of establishments of health care are made, at management of branch, integration of the public and private institutions of health care.

3D GRAPHICS IN DESIGN The article discusses the basic concepts of graphics, 3D modeling software systems and their advantages. The main reasons for the widespread use of three-dimensional modeling in the design of industrial facilities are highlighted. The essence of three-dimensional modeling is described, as well as companies that use these technologies are described. Methods of teaching 3D graphics in the conditions of modern development of computer-aided design systems are considered. It is concluded that 3D design technologies are a huge step forward in engineering activities and its use significantly increases the competitiveness of the design organization in the market.

ANTHROPOGENETIC RESEARCH OF THE POPULATION OF THE CENTRAL RUSSIA Anthropogenetic studying of a genofund of the population of 10 areas of 6 areas of the Central Russia by data about frequencies of surnames and haplogroups mtDNA is spent. On the average on region has made r f =0,00033, varying from 0,00001 in Borovsk area of the Kaluga region to 0,00092 in Cheremisinovsky area of Kursk region. Most often meeting among Russian population of the Belgorod region are gaplogroups H, U, J on which, in general, 67,5 % are necessary.

Questions of medical and social examination and rehabilitation of disabled people with the consequences of military trauma The expert characteristics of the clinical and functional status of the military personnel for the first time recognized as disabled in 2016 because of «military trauma» are considered. It is known that the objectification of methods of expert rehabilitation diagnosis in the implementation of medical and social expertise in the establishment of disability and the development of individual programs of rehabilitation/habilitation of disabled people-one of the main objectives of the concept of «Improvement of the state system of medical and social expertise and rehabilitation of disabled people.» In accordance with this provision, clinical and expert indicators are analyzed, confirmed by the data of expert rehabilitation diagnostics, allowing to objectify the impaired functions and structures of the body of soldiers who have received a military injury, when examined in the Bureau of medical and social expertise. The main clinical and functional syndromes that have expert significance and have influenced the adoption of expert decisions in the establishment of disability groups are presented. The article describes in detail the contraindicated and shown factors of the recommended labor activity, which should be guided in the employment of disabled people from among the former soldiers. The use of evidence-based recommendations in practice makes it possible to determine the forms and conditions of employment in normal or specially created working conditions for the rational employment and socialization of servicemen who have become disabled. Referring to the updated normative legal acts, taking into account the principle of inseparability of the medical and social examination procedure from the formation of individual programs of rehabilitation/habilitation of disabled persons, the authors illustrate the possibilities of professional rehabilitation and employment of military personnel who have different groups of disability due to «military trauma».

Some issues of law enforcement monitoring in modern Russia in the context of combating corruption in the field of public administration This article analyses selected organisational and legal aspects of law enforcement monitoring in modern Russia from the perspective of the implementation of the state anti-corruption policy. We defined the legal basis of legal monitoring. The author's position is stated regarding the following five points: the essence of law enforcement; goals and objectives of monitoring law enforcement, their correlation with the SMART; the content of the annual report of the Government of the Russian Federation to the President of Russia; the real significance of the Ministry of Justice of Russia in the process of monitoring law enforcement; the role of the Ministry of Justice of Russia in the preparation process; the formation of the annual report of the Government of the Russian Federation to the President of Russia. It is concluded that one of the main problems of law enforcement at the present time is the ever-increasing amount of legislation and law-enforcement acts based on it, in the presence of negative factors that adversely affect the effectiveness and uniformity of law enforcement, and ultimately the unity of the legal medium of Russia. In turn, this affects the anti-corruption measures' implementation effectiveness in the field of public administration directly negatively.

Calculation of statistical characteristics of rock strength certificate Introduction. At risk assessment in problems of mining geomechanics it is necessary to consider statistical characteristics of rock physical parameters variability and interconnection - mean square deviations and coefficients of correlation of these parameters for each engineering-geological element. In calculations of career slopes stability rock strength certificate parameters are used - coupling and internal friction angle. Neglection of mutual correlation between rock strength certificate parameters leads to settlement indicator errors overestimate/understating, while the neglection of the coefficient of stability and geometrical parameters of a slope leads to understating/overestimate of degree of risk. Research aim and methodology. On the basis of the regression analysis the present research aims to consider ways of receiving elements of a correlation matrix for various ways of creating rock strength certificate according to the results of laboratory researches of the samples - at monoaxial compression and stretching and by the one-plane cut method. Results. The formulae necessary to calculate rock strength certificate parameters covariance matrix are introduced in the article. It is established that the way of calculating covariance matrix depends on the applied samples laboratory test method. The examples have shown that the correlation coefficient between coupling and of internal friction coefficient can be of various signs. Scope of results. Values of rock strength certificate parameters statistical characteristics, calculated by the offered technique, can be used to solve rock geomechanics probabilistic problems.

Problem of Combined Selenium and Iodine Deficiency in the Development of Thyroid Pathology The article organizes data on the role of iodine and selenium deficiency in the functioning of the thyroid gland (TG), its importance in the development of thyropathies. Markers needed to determine the provision of the organism with iodine and selenium are given, as well as deficiency conditions associated with these trace elements, and their physiological daily doses are recommended. It was concluded that the use of selenium compounds (average dose 75 μg/day) and iodine (average dose 150 μg/day) with the purpose of prevention or treatment in physiological doses is safe, can reduce the severity or inhibit pathological processes in TG, including improving the course of autoimmune diseases.

Experimental study of immunotoxic effects of pseudomonas fluorescens ЕК-5-93 as an organo-phosphorus toxic compounds’ biodestructor There article reveals the results of study of immunotoxic properties of organo-phosphorus substances' biodestructuring strain Pseudomonas fluorescens ЕК-5-93, they are essential for assessment of its harmful effect and environmental safety.

Organizational and legal basis for the use of police robotic systems in the Internal Affairs bodies of the Russian Federation The relevance of the study: special and dual-use robotic systems are classified as one of the nine priority areas for the development of science, technology and technology in the Russian Federation. State policy in this area involves the adoption of appropriate technical means for the police. There are technological possibilities for this, but the successful implementation of police robotics is impossible without the development of a set of organizational measures and an appropriate regulatory framework. The problem statement: the police units that are part of the most numerous law enforcement Agency in the Russian Federation, the Ministry of internal Affairs, operate under conditions of increasing overload of personnel, while simultaneously facing new challenges and threats from violators of the law and their criminal communities. Taking into account these circumstances, the Ministry's leadership decided to use police robotics among other measures to improve the efficiency of operational and official activities, which was reflected in the draft Concept of scientific and technological development of the Ministry of internal Affairs of Russia until 2030. The introduction of these technologies is associated with significant budget expenditures and certain changes in the organization of daily operational and service activities. For the implementation of the proposed measures for the introduction of police robotics, an appropriate scientific justification is required. The aim of the research is to develop theoretical foundations for the organization and development of the regulatory legal framework for the use of police robotic systems in the internal Affairs bodies of the Russian Federation. The research methods: dialectics, analysis, information modeling, statistics. The results and key conclusions: the terminology of the subject area is clarified, the author's definition of the term «police robot» is proposed. The necessity of mass introduction and application of police robotics in the system of the Ministry of internal Affairs of Russia is proved. The qualitative and quantitative composition of the implemented police robotics is evaluated. It is proposed to use a functional approach for robotization of police functions and the principle of collective use of technological capabilities in the interests of all interested divisions of the internal Affairs body, taking into account the provisions of the theory of Queuing.

EQUIPMENT FOR THE CONTRUCTION OF REINFORCED ICE CROSSINGS Most of the northern regions of Russia lacks the capital roads and bridges. The rapid development of the oil and gas industry requires constant development of roads, which in turn is connected with enormous cost. One way out of this difficult situation, the creation of temporary roads and ice crossings, operating in winter. In this paper, we propose to change the design of the thermosyphon, namely to use the thermosyphon with a constant radius of curvature. This form allows you to extract thermosyphon with lower labor costs without compromising the integrity of the ice and accrued thermosyphon, it can be used repeatedly throughout the winter period. The paper proposes a new system for extracting, representing a leading two and one holding a roller located on different sides of the thermosyphon, for the best retention and downforce. The rolls will be driven by technological machine with a mechanical or hydraulic transmission. Application of the proposed measures allows to reduce the time to strengthen the ice crossing and reduce the complexity of service ice roads.

The Ontologico-Political Aspect of Heidegger's Thought The article provides the ontological context for a possible Heideggerian solution of a politico-philosophical problem. Both the ontological issue and the politico-philosophical issue share the same problematic structure of the relation between the general and the particular. The general is the cause and the particular is the effect. Hence, this issue is the ontological issue of causality. The article demonstrates that how the Heideggerian thought of Being dwells on the issue of cause, and how the introduction of the ontological difference, and interdependence, of being and Being can shed light on the political aspect of thought.

BLOCK OF MODELING AND FORECASTING OF GAS NETWORKS OPERATIONAL MODES FOR SUPPORTING DISPATCHER DECISION SYSTEM The new methods of automation of dispatcher control were designed to help managers to solve the problem of maintaining a balanced operational regime of a gas transportation system. Forecasting of gas demand and modeling of operational modes of a gas transportation system are supplemented by an automated decision support system.

Modeling the Configuration of a Robotic Gripper for Handling Agricultural Products Purpose of research. Improvement of quality and speed of harvesting agricultural products through the development of models, control algorithms and multi-criteria optimization of the robotic gripper configuration. Methods. To achieve this goal, we have used the methods of mathematical and computer modeling, multi-criteria optimization, the theory of object-oriented design and programming. The mathematical model of the kinematic scheme of the prototype of the robotic gripper, its geometric constraints and objective functions used for optimization are described. Results. It has been performed a review of approaches to robotic harvesting of agricultural products, confirming the relevance of this study of robotic gripper configurations, which provides reliable fixation of an object without causing damage. The results of experiments on evaluating the developed algorithms and a software system for optimizing the configuration of a robotic gripper are presented. The developed software system AgroGripModeling for modeling the configuration of a robotic gripper using three a posteriori algorithms NSGA-II, MOGWO and MOPSO for multicriteria optimization is tested in the design of a prototype of a four-fingered gripper with a vacuum bellows for picking tomatoes. Conclusion. When designing a robotic gripper, it is necessary to take into account the variety of manipulated objects, the complexity of their identification and guidance of the manipulator in a complex natural environment with obstacles. The task of optimizing the capture mechanism is associated with the fulfillment of a number of conflicting requirements for reliability, softness, accuracy, speed, energy efficiency, which form a complex space for finding solutions. The developed AgroGripModeling software system provides modeling of the robotic gripping configuration and its quality assessment using three a posteriori algorithms NSGA-II, MOGWO and MOPSO. The system was tested with multicriteria optimization of the configuration of a prototype of a four-fingered gripper with a vacuum bellows for picking tomatoes.

DETERMINATIONS OF PREDICTION VALUES OF THE DEGREE OF PURRIFICATION OF ULTRASONIC PROCESSING OF OPTICAL MATERIALS The solution of the problem of estimating the forecast of the degree of purification during ultrasonic processing of optical materials is considered. Using the methods of principal components and correlation analysis the grouping of input variables and determination of the most important impact parameters were carried out. A solution and models are proposed using the methods of fuzzy set theory, fuzzy relations and fuzzy inference in the analysis of expert assessments of the degree of sample processing.

MEAT PRODUCTIVITY OF SHEEP OF DIFFERENT GENOTYPES The article presents the results of studying the8 main indicators of meat productivity of crossbred young animals obtained as a result of crossing fine-fleeced queens with rams of the Dzhalginsky and Stavropol breeds. The effectiveness of the use of sheep-producers of the Dzhalginsky merino breed on sheep of the Soviet Merino breed has been experimentally proven, in order to increase the slaughter qualities, morphological and varietal composition of carcasses in the resulting offspring. Introduction. The economic priorities of the sheep industry have changed. Animals with a combined nature of productivity have become more in demand due to their higher competitiveness and thus provide the necessary level of efficiency of sheep breeding. Subsidies paid for the wool produced do not fully cover the costs of merino wool production, but contribute to the formation of the overall profitability of sheep farming. From this we can conclude that in this segment of sheep breeding it is important, without losing the level and quality of wool productivity, to increase meat productivity. The purpose of the scientific experiment was to compare the productive qualities of the crossbreeds obtained from crossing the breeds Soviet merino, Dzhalginskaya and Stavropol. Object. The object of research was crossbred sheep of 6 months of age. Material and methods. To study the issue, 3 groups of sheep with 70 heads aged from 3.5 to 4.5 years were formed according to the 1 principle of analog groups. In all three groups, sheep of the Soviet Merino breed acted as the mother base. Soviet Merino sheep (control group), as well as Dzhalginsky merino and Stavropol breeds were selected for insemination of ewes. Experimental groups of sheep with genotypes were formed from the resulting lambing of young animals: Soviet Merino; 1/2 Stavropol + 1/2 Soviet Merino, 1/2 Dzhalginsky merino +1 /2 Soviet Merino. At the end of the planned growing period, a control slaughter of sheep was carried out. A comprehensive assessment of the meat productivity of sheep was carried out by assessing the live weight before slaughter and post-slaughter determination of carcass mass, internal fat mass, ratio in carcass pulp and bones, meat yield by grade. Results and conclusions. The young animals of the experimental groups had superiority over the control in terms of lifetime indicators of meat productivity. Differences remained in the post-slaughter characteristics. Animals 2 and 3 groups were distinguished by the highest yield of cuts of the first grade. This indicator it turned out to be higher than in the control group by 4.5% (half-blooded lambs of the Dzhalginsky breed) and 1.9% (half-blooded lambs of the Stavropol breed). The consequence of the established superiority was a smaller yield of bones from the carcass in these experimental groups of animals. As a result, according to the meat content coefficient, which shows the degree of the ratio of pulp and bones in the carcass, we recorded the superiority of 4 crossbred young animals in the experimental groups. This gives reason to assert that the qualitative characteristics of meat productivity were expressed to a greater extent in the sheep of the 2 experimental group. Thus, the effectiveness of the use of sheep-producers of the Dzhalginsky merino breed has been experimentally proven on sheep of the Soviet merino breed in order to increase the slaughter qualities, morphological and varietal composition of carcasses in offspring.

INFLUENCE OF MORPHOLOGICAL MANIFESTATIONS OF CONNECTIVE TISSUE DYSPLASIA IN CHILDREN WITH ANOMALIES OF THE URINARY SYSTEM Introduction. In the study determined accessible and highly specific morphological research techniques to diagnose the severity of the connective tissue dysplasia (CTD) in children with anomalies of the urinary system (AUS). Materials and methods. The work is based on the results of treatment of 143 children aged 6 months to 18 years with the diagnosis of PUS obstruction with hydronephrosis and vesicoureteral reflux I-V degrees. In children with AUS (hydronephrosis and vesicoureteral reflux), there is a strong direct correlation between the degree of CTD and the severity of the disease (p = 0.001, χ2 = 20.985). Results. In the morphological study of ureters using immunohistochemistry in patients with severe vesicoureteral reflux and hydronephrosis against the background of severe manifestations of CTD, significant changes in the structure of connective tissue fibers were observed in the form of significant fragmentation and chaotic arrangement of the fibers of collagens type I and type IV. The elastric ureteric framework was subjected to significant changes (p = 0.001, χ2 = 26.796). Conclusions. Thus, the surgical approach in the treatment of AUS in children must be differentiated depending on the degree of CTD expression.

Comparative analysis of key parameters of photonic nanojets from axisymmetric nonspherical microparticles The effect of “photonic nanojet” (PNJ) arising in the near-field scattering region on the surface of dielectric axisymmetric microparticles (hemisphere, axicon, and combined particles) under optical illumination is theoretically considered. Key PNJ parameters (length, width, and peak intensity) are numerically calculated using the method of discrete-dipole approximation; the dependence of these parameters on the geometric shape of microparticles is analyzed. We show that the use of a special type of combined transparent particles, which consists of an axicon and two attached hemispheres, allows ultra-localized light fluxes with a peak intensity considerably exceeding the corresponding values for particles of simple shapes (hemisphere and axicon).

ACTUAL PROBLEMS OF STATE AUDIT AND THE EFFECTIVENESS OF INTERNAL CONTROL IN THE FIELD OF HEALTHCARE IN THE RUSSIAN FEDERATION Health care is subject to public administration. Given the problems of socio-economic nature, the level of provision of medical services to the population is not conducive to its sustainable development. Effective mechanisms are needed for the implementation of state programs and public health audits at the federal, regional and municipal levels. The Accounts Chamber of the Russian Federation is the highest body of state audit in the field of control over the expenditure of funds in health care. Internal audit in the field of health care is carried out by executive authorities. State audit is one of the mechanisms of state regulation and development of this sphere. Most of the reforms come down to optimizing costs at the expense of quality. The absence of changes in the social indicators of mortality and fertility, the absence of a significant increase in satisfaction with the quality of medical services is evidence of the ineffectiveness of the public health system. The inefficiency of planning, implementation of decisions and control is expressed in the misuse of budgetary funds. It is necessary to change the format of financing the public health sector, reorienting managers not to fully absorb financial resources, but to their rational and economical use.

STABILITY OF SMALL-SCALE PERTURBATIONS IN DIFFERENTIALLY ROTATING PLASMAS The initial-value problem for linearized equation describing small-scale flute modes in plasmas with nonuniform rotation is solved. It is shown that the differential rotation modifies qualitative characteristics of interchange bubbles such as their shape and the temporal dependence of amplitude. The radial wavelength of perturbations decreases with time, while their amplitude evolves according to a power law, instead of the usual exponential behavior. The radial contraction of the wavelength leads, on the one hand, to the decrease of the plasma displacement, but, on the other hand, to the increase of the perturbed electric field. As a result, the energy of perturbations increases even in the case when the amplitude of perturbed potential stays constant. Small-scale perturbations become stable if the ion gyroviscosity is taken into account.

Formation of competitive business environment on the market of chemical products: trends and prospects The article discusses the business environment of the Russian chemical market. There are internal and external factors of the environment and its influence to the business competitiveness. There are given development trends of the domestic chemical industry, identified issues for the formation of a highly competitive business environment. It concludes with a deduction about future development of Russian business in chemical industry.

Service for Disaster Medicine: The Main Results of its Activity in 2011 and its Tasks for the Nearest Future The main results of activity of Service for Disaster Medicine (SDM) of Ministry of Health and Social Development of Russia in 2011 are discussed. A multifaceted complex of measures implemented by the Headquarters of All Russian Service for Disaster Medicine (ARSDM) and by Territorial Centers for Disaster Medicine (TCDM) in 2011 is presented. The main tasks facing SDM of Ministry of Health and Social Development of Russia in 2012 are defined.

The state of measures to support small and medium-sized businesses in municipalities on the example of the Closed Administrative territorial formation of Pervomaisky and Yuryansky district The article analyzes the measures used in practice at the municipal level to support small and medium-sized businesses. The author explores the problems of public-private partnership and business support as conditions for increasing financial autonomy and stability of municipal budgets, in general, socio-economic well-being, draws attention not to the problems of a healthy competitive environment in territories with a special legal status on specific examples.

Computational prediction of the strength of steels after laser chemical-thermal treatment The paper presents an algorithm for calculating the predicted hardening of steels subjected to surface hardening using laser thermal and chemical-thermal treatment. An acceptable convergence of calculated and experimental results is shown, which confirms the adequacy of the algorithm for predicting the strength of iron-based alloys.

DETERMINATION OF THE RADIUS OF CURVATURE AND THE SCHEME OF THE CARRIAGE INSCRIBING AFTER THERMAL TRACK DISCHARGE The results of research conducted by VNIIZhT specialists about the impossibility of thermal track discharge under the train are presented. The calculations to determine the radius of curvature of rails after thermal track discharge in a straight and curve sections of track as well as radiuses of jammed inscribing of carriage and escapement of locomotive bogie are made.

The role of argumentation in teaching the theme "Polite refusal" at school The article is devoted to the ways of using argumentation in teaching pupils speech culture. We cannot deny somebody’s request politely without persuasive arguments. The author describes methodical means and different kinds of exercises aimed at achieving the objective of the lesson.

Veterinary and sanitary assessment of broiler chicken meat when using feed probiotics in the diet Introduction. In order to increase the production of poultry meat and reduce its cost, it is necessary to introduce advanced scientific achievements into production. The main factor affecting the productivity of birds is high-grade and good-quality feeding, which is achieved by adding biologically active substances to the diet. One of which is probiotics and prebiotics, which are widely used not only for the prevention of various diseases, but also for stimulating growth. Studies show that probiotics are widely used in poultry farming both as a biological regulator of metabolism in the poultry body and as productivity stimulants. If microbiological feed additives have been used for a long time, then living microorganisms began to be used relatively recently. The purpose of this work was to study the veterinary and sanitary indicators of broiler slaughter products when adding Royal Feed E-500 and Bioside feed probiotics to the diet. Materials and methods . The production experiment was carried out on 3 groups of one-day broiler chickens with 50 heads in each group. The first group received the Royal Feed E-500 probiotic with a diet at the rate of 4 % of the main diet, the second group received Bioside at the rate of 2.5 % of the main diet. The third group served as a control and was kept on a diet adopted by the farm. At the end of the experiment, the birds were slaughtered and the examination was carried out according to the Rules of veterinary and sanitary examination of meat. Results and discussion . On day 42, the live weight gain was higher in the experimental groups compared to the control by 2.52-3.7 %. During external examination of internal organs, pathological changes were not found in both experimental and control groups. In the experimental and control groups, the content of toxic elements, radionuclides, pesticides did not exceed MAL. During tasting assessment of the juiciness, aroma, tenderness and taste of the broth from poultry meat of the experimental groups, the scores were higher compared to the control. During microbiological studies, it was found that the pectoral muscles of all groups of broiler chickens were contaminated to a lesser extent than the femoral ones. Conclusion . Probiotic preparations Royal Feed E-500 and Bioside for broiler chickens does not cause pathological changes and improves the quality of slaughter products according to organoleptic, physico-chemical and bacteriological indicators, which meets the requirements of GOST for good-quality meat.

MODULAR COMPLEX FOR IMPROVING EDUCATION AND YOUTH ASSISTANCE IN A MARKET ECONOMY Describes the development and use for teaching students a portable multifunctional modular complex for improvement: 1 - teaching schoolchildren and students in economics, safety of life, labor protection, physics, technology, etc.; 2 - the competitiveness of graduates in employment; 3 - protection of students, graduates and their families from many risks and problems, useless expenditure of their money, time and labor. It will help teachers, schoolchildren, students and their families: 1 - to understand and use the laws of the market economy and the important information on the basis of more effective teaching methods and skilled assistance to them; 2 - to obtain the necessary knowledge, skills and experience faster, easier and cheaper on the basis of best use of the potential of their families, schools and the university.

Monotonicity of certain classesof functions related with Cusa - Huygens inequality The theory of analytical inequalities is still a very popular field of investigation of many authors. In this note, we analyze the monotonicity of certain classes of functions related with the Cusa - Huygens inequality, and propose some open problems in this direction.

The "Science-Power" Relationship: from M.K. Petrov to A.P. Ogurtsov In the article, the discussion-heuristic potential of the basic postulates of Mikhail Petrov's political philosophy has been reconstructed. Their connection with the concept of enslaved reason and cringing reason (formulated by Ch. Milosh and B.I. Pruzhinin) as well as with the analysis of the relationship between science and authority in the work of A.P. Ogurtsov is shown. In conclusion, the author puts forward the idea of reevaluating of Soviet ways to link the modern Russia to the Russian history until 1917, after 1917 and after 1991 including ways to connect science with other spheres of public life.

Comparison of vacuum deposition techniques to obtain high-temperature scm type shell structures The paper considers the main methods of formation of layered composite materials (SCM). The advantages and disadvantages of these methods are presented. Experiments were carried out to obtain laboratory samples of SCM based on refractory metals Nb-Mo. A study of the microstructure of samples was carried out.

PUNISHMENT AS A MORAL, PHILOSOPHICAL AND LEGAL CATEGORIES (Proceedings of the roundtable, devoted to the discussion of works on current issues of punishment by Doctor of Law, Professor, Honored Lawyer of the Republic Azerbaijan Ilham Mammadhasan oglu Rahimov) The review covers the materials of the round table, held on March 9, 2016 at the Academy of the Investigative Committee of Russia, where the discussion of the monographs by Professor I.M. Rahimov "Crime and Punishment" (Moscow, 2012), "The philosophy of crime and punishment" (St. Petersburg, 2015), "On the moral of punishment" (St. Petersburg, 2016) took place. However, the conversation was not limited only to the analysis of these studies, and went far beyond the publications, which is understandable due to the significance of the problem. For several centuries, scientists have struggled to resolve a number of issues: the right of punishment, the nature and content of penalties, goals and functions of punishment, their means of implementation, etc. Therefore, a discussion on many issues has turned out sharp, obviously staying within the frames of scientific debate. The roundtable was attended by deputies of the State Duma of the Russian Federation, well-known scientists from Moscow, St. Petersburg, Vladivostok, Yelets, Omsk and other Russian cities, as well as representatives of the scientific community of Azerbaijan. The roundtable was opened by A.M. Bagmet, Acting Rector of the Academy of the Investigative Committee of the Russian Federation, PhD in Law, Major-General of Justice. A.I. Bastrykin, Chairman of the Investigative Committee of the Russian Federation, Doctor of Law, Justice General. presented his opening speech.

PARAMETERS OF FUNCTIONAL POWER DURING STANDARD PHYSICAL LOAD IN JUDOKAS WITH DIFFERENT QUALIFICATIONS We studied the parameters of functional power after standard physical activity in athletes involved in judo. 31 athletes took part, qualifications from the first category to the master of sports. Age observed from 17 to 21 years. We studied the vital capacity of the lungs, maximum ventilation of the lungs, the strength of the respiratory muscles during inhalation and exhalation in the state of muscle rest and after standard physical activity in the PWC170 test. We used an electronic spirometer, "Fucuda-3000", (Japan), pneumomanometer. The obtained data were statistically processed with the definition of Student's t-test. The data obtained showed that with an increase in sports qualification, judokas develop external respiration indicators (vital lung capacity and maximum lung ventilation, p<0.001). As for the strength of the respiratory muscles during inhalation and exhalation, the difference in the groups under consideration was not registered. After a standard physical load, a significant (p<0.05) increase in power was noted in masters of sports in relation to athletes of the 2nd group. The parameter maximum oxygen consumption in highly qualified athletes prevails by 11 % (p<0.001). The oxygen pulse index is 16 % higher than in the athletes of the second group (p<0.01).

An approximate algorithm for choosing the optimal subset of nodes in the Angara interconnect with failures The Angara high-speed interconnect with multidimensional torus topology is under development in Scientific Research Center for Electronic Computer Technology. During the utilization of the Angara interconnect in cluster systems, there exist busy and failed nodes. Thus, there is a problem of finding an optimal cluster node subset such that the network traffic belongs to this node subset and the node subset size is not less than a given size. The paper presents an approximate algorithm for solving this problem.

SPORT-ORIENTED APPROACH TO PHYSICAL EDUCATION OF STUDENT YOUTH AT HIGHER EDUCATIONAL INSTITUTIONS OF THE KRASNOYARSK TERRITORY (ON THE EXAMPLE OF SUCH SPORTS SPECIALIZATIONS AS VOLLEYBALL AND SOCCER) According to some scientists, one of the ways of qualitative solution of the problem of the insufficient level of physical development and functional readiness of modern young people to physical exercises is a sportoriented approach to physical education of the youth in educational institutions. So, classes of physical education among students are held in several higher educational institutions of Krasnoyarsk in the framework of certain sport specializations. However, there are significant methodological differences in the organization of educational process on the basis of this approach. The aim of the authors’ research was to identify the most effective methods of organization and holding classes in the framework of sport-oriented approach to physical education of student youth.

Digital technologies as a tool for regulating social relations Global digitalization sets new requirements and standards for the interaction of various fields and practices of human activity, in particular the combination of legal and technical regulators, without which it is impossible to achieve an effective and adequate legal regulation of public relations in the digital era. This article discusses the possibility and necessity of integrating classical legal institutions with components of the digital environment. It analyses the idea of reflection of law as a social regulator in the architecture of programs and examines existing practices of using digital technologies in legal activities. The subject of the study includes domestic and foreign legal doctrines dedicated to the issues of digitalization and the practical implementation of information technology in legal activities. The following methods of scientific research were used in this study: statistical; dogmatic; comparative-legal; synergetic, as well as logical, functional and systematic. The novelty of the study is confirmed by the need to bring together the legal and information system during the rapid process of digitalisation of all fields of society.The author concludes that new technological solutions can and will undoubtedly become indispensable supporting solutions in legal activity, however, today the level of technology development does not allow to fully replace humans with technology.

The genetic patterns of severe therapeutically resistant asthma as shown by a transcriptomic study: An analysis of gene ontology and KEGG pathways The leading mechanisms and causes of severe therapy resistant asthma are poorly understood. The aim of this study was to define global patterns of gene expression in adults with severe therapy-resistant asthma. Performed 24-week prospective interventional study in parallel groups. Severe asthma patients was aposterior divided at therapy sensitive and resistant patients according to ATS criteria. Global transcriptome profile was characterized using the Affymetrix HuGene ST1.0 chip.

AN OVERGROUP AND A POISSON TRANSFORM FOR A PARA-HERMITIAN SPACE For canonical representations on the para-Hermitian space G/H, G =SL(2,R), H the diagonal subgroup (so that G/H is a hyperboloid of one sheet in R3), we determine explicitly the interaction of Lie operators of the overgroup G×G with Poisson transforms related to canonical representations

Traditional and "new" forms of leisure for rural youth in Western Siberia in the 1920s State in the 1920s led a conscious policy of eradicating the "remnants" of the past. First of all, the authorities tried to destroy the rites and traditions that bear religious symbolism. Against the background of the introduction of new solemn traditions, a special place is occupied by such a phenomenon as the celebration of old holidays in a new way. Under conditions of social tension, an intensive search was underway for consolidated principles, including in the leisure sphere. The article discusses various forms of leisure of peasant youth. A clash of innovations and traditions in various aspects of the leisure sphere of life is revealed. The features of this process are noted on the example of the West Siberian region. On the example of evening parties, which, as before, occupied a leading place in the sphere of leisure, the transformation of the event and the attitude of peasants to the new format of the event are shown.

Formation of the principles of piano primary training during the soviet period The present paper analyses methodical fundamentals of the primary level of professional education constituting the core of methodical views of the period of formation of Soviet piano methods. Common features of the presented theories with methodical views of the previous period are determined; some contradictions in the arrangement of semantic dominants (emphases) on revealing (determination) of fundamental principles of primary professional piano teaching are indicated. Necessity of the detailed investigation of the present historical period in the view of the possibility of educational work modernization in the conditions of formation of the fundamentals of special professional training is argued.

History of Spasovoznesenski cathedral The article deals with the construction, destruction and restoration of Spasovoznesenski cathedral in Simbirsk -Ulyanovsk.

STUDY OF PLATE BENDING BY THE METHOD OF CONCENTRATED DEFORMATIONS The article deals with the method of forming the stiffness matrix of bent plates that are rigidly pinched at the edges based on the method of concentrated deformations.

PROBLEMS THAT REDUCE THE STABILITY OF THE FUNCTIONING OF THE FOOD SYSTEM OF KAZAKHSTAN The article investigates the food system of the Republic, its constituent elements and the problems hindering its sustainable development. The aim is to obtain scientific and practical results that identify the problems of sustainability of the food system of Kazakhstan. The study of the current state of the food system and the economic complex that ensures its functioning, suggests that the problem of sustainability is important given the fact that a country with sufficient resource potential (natural, labor, logistics, financial, etc.) can not provide: 1) meeting the needs of the food market and the population in food products of domestic production at the level of required consumption; 2) the production of quality and competitive products. They accumulate the whole range of problematic issues on the formation of an effective economic structure of the agro-industrial complex of the country and the creation of conditions for sustainable behavior of the food system and economic entities included in it.

The Factors’ Influence on the Functioning of the Agricultural Insurance Market The article is aimed at identifying modern features of insurance in the agricultural sector of the Ukrainian economy and defining the factors of influence on the agricultural insurance market. Agriculture is highly risky, and the issue of using agricultural insurance as a method of reducing future losses of benefits is topical. The article discloses interpretation of the terms of «insurance» and «agricultural insurance» and also presents the types of possible risks arising in the activities of agricultural enterprises. The performance indicators of leading insurance companies in the field of agricultural insurance are analyzed. The current state and dynamics of insurance of agricultural risks, which arise both in the field of crop production and in livestock, are researched. This will allow predicting the future prospects of the market for insurance services and products, as well as finding possible optimal ways to solve the problems of product insurance, faced by the agricultural producers. The main factors influencing the efficiency of the insurance market in the agricultural insurance sector are allocated. The basic principles of insurance of agricultural products with the State support are analyzed. It is defined that the further development of agricultural insurance should be directed towards creating a profitable and safe environment for all participants in the agricultural market, which provides for the distribution of risks between agricultural producers, processing enterprises, banks, insurance companies and the State. The agricultural insurance of risks creates possibilities for advantageous harmonizing the interests of participants in the agricultural insurance market and the State as a party whose first priority is to ensure stable economic growth, the well-being of citizens and their social protection.

A Real-Time Historical Database of Macroeconomic Indicators for Russia We compiled, as part of a research project of Bank of Russia, a database on the revisions of a large set of short-term economic indicators and published it on the Bank of Russia website. The Research and Forecasting Department of the Bank of Russia plans to update this database in the future. We also perform an illustrative analysis of the properties of the revisions for a number of indicators. The preliminary results of this work indicate that the magnitude of the revisions is in many cases substantial.

On publicly-legal nature of legal relations in the sphere of procurement In science a long time is the debate on the legal nature of legal relations in the area of procurement. In this article the author connects the criteria of public relations with the relations in the sphere of procurement. By reasoning and analysis, the author proposes to attribute relationships in procurement more to public than to private law.

Diffusion of interstitial magnesium in dislocation-free silicon The diffusion of magnesium impurity in the temperature range T = 600-800° C in a dislocation-free singlecrystal silicon wafers of p-type was studied. As a source for diffusion, served the surface layer of a wafer doped by the ion implantation technique. The implantation was carried out at the ion energy 150 keV, fluences 5 • 1014 and 2 • 1015cm-2. The diffusion coefficient of interstitial magnesium donor centers (Di) was determined by measuring the depth of p-«-junction, which was formed in a sample due to annealing for time t at a given T. As a result of investigation, the dependence Di (T) was found for the first time. The data showed that the diffusion process proceeds mainly via the interstitial mechanism.

Optimization of the quality characteristics of the surface layer of parts when hardening by PPD methods A comparative analysis of a complex of technological process models for predicting certain parameters of surface hardening of heavy-loaded parts is carried out. A method of analytical prediction of the quality parameters of the surface layer of parts hardened by surface-plastic deformation methods is developed. A model of optimization of technological processes is presented, in which the target function is the strain intensity.

POSITIONING OF THE POLITICAL ELITE OF MODERN RUSSIA IN THE CONTEXT OF COMPARISONS OF DIFFERENT POLITICAL SYSTEMS AND REGIMES The article analyzes the main theoretical dilemma of modern elitology prevailing since the second half of the twentieth century. We are talking about neonationalists and pluralistic doctrines. We examine the experience of formation of elitogenesis in the states with developed democratic institutions. Emphasize the socio- historical and natural-geographical determinants of Russian elitogenesis, its inclination to hierarchical and not polyarchical forms. The description of the expert survey is given, the results of which characterize the current state of Russian political elites, the formation of which coincides with the period of transition from authoritarian to democratic institutions of elitogenesis. The final conclusion of the survey: democratic transition has not yet taken place and requires significant adjustments related to the peculiarities of the Russian historical and contemporary experience.

MODERN APPROACHES TO THE TREATMENT OF HEPATIC METASTASES FROM NEUROENDOCRINE TUMORS (LITERATURE REVIEW) Originating from cells of the diffuse neuroendocrine system, neuroendocrine tumors are able to produce biogenic amines and peptide hormones. Due to the significantly different list of biologically active compounds and level of activity of secretory cells in tumor tissues, their clinical manifestations varies. Liver is one of the most frequent targeted organs for metastasizing this type of tumors, regardless of localization. After the patients being diagnosed, all the treatment measures are focused on two aspects. The first is to suppress the clinical symptoms and improve the living quality. The second one, an increase in life expectancy. Among all the potentially effectible treatments, surgical resection is the only one that may radically kill the disease. However, its application are limited in some cases. In this regard, in the strategy of therapeutic approaches of neuroendocrine tumors with metastases in the liver, a combination of medical, surgical and renal surgical methods comes to the fore.

EXPERIENCE OF FOREIGN COUNTRIES IN THE USE OF ALTERNATIVE FUELS A thorough study of international experience of using alternative fuels has been conducted, the feasibility of their use in the energy balance of the world has been analyzed.

THE VALUE OF BUSINESS ENGLISH IN THE SPHERE OF INTERNATIONAL COOPERATION This article describes the importance of the English language in business and its immediate prospects for companies. Nowadays the demand for business English greatly increases. International companies do not want to miss a good specialist and organize free business English courses for their employees.

USE OF PHYSICAL EDUCATION AS A METHOD OF REHABILITATION The article considers the possibility of using physical culture as a tool of rehabilitation.

COMPARISON OF THE IMMEDIATE AND MEDIUM-TERM CLINICAL OUTCOMES OF TREATMENT OF PATIENTS WITH PARTIAL-THICKNESS ROTATOR CUFFTEARS OF VARIOUS DEPTH AND LOCALIZATION Objective - To compare the effectiveness of conservative treatment, arthroscopic debridement and anchor fixation in patients with partial-thickness rotator cuff tears of various depth and localization.Material and methods. The study was a prospective randomized controlled one with the formation of three compared groups of 120 patients older than 55 years with MR-signs of an symptomatic isolated atraumatic partial tear of the supraspinatus tendon. Patients of group I were treated conservatively, group II - performed subacromial decompression, in group III, in addition to decompression, an anchor fixation was performed. Each group contained two subgroups of 60 patients with partial tears of the bursal (B-PTRCT) and articular surface of the tendons of the rotator cuff of the shoulder (PASTA, A-PTRCT), each of which was formed of four subgroups of 15 patients depending on the depth of the tendon tear: 90%. The observation was carried out for 12 months, assessing the functional state of patients before treatment, as well as after 3, 6 and 12 months. using the Constant scale. Over the entire study period, 324 patients were monitored, including 96 women and 228 men, with an average age of 65 years. There were no statistically significant differences in the overall structure of patients in the study groups. The number of patients and the comparability of groups and subgroups according to general and radiological signs made it possible to compare treatment efficacy with a significance level of α = 0.05 and a statistical power of 85%. Results. The average functional results of conservative treatment, acromioplasty and cuff suture without taking into account the depth and localization of damage do not differ significantly, however, the pain syndrome and daily activity of patients were better after arthroscopic anchor fixation. In B-PTRCT, the average result depended on the treatment tactics chosen is not significant. In PASTA, the average functional result was better after the suture. The average results of the suture did not differ much in patients with B-PTRCT and PASTA, while the results of conservative treatment and arthroscopic decompression were significantly worse for PASTA. The revealed differences were most significant at a damage depth of 20-50%, partially remained in the 50-90% group and were absent at breaks of more than 90% and less than 20% of the tendon thickness. Arthroscopic suture was accompanied by significantly better results than alternative treatments with PASTA with a depth of more than 20% and with PASTA with a depth of more than 50%. Conclusion. To select a method for treating patients with partial-thickness rotator cuff tears of the shoulder, it is necessary to determine the depth and localization of the tear. The fixation of the supraspinatus tendon, partially torn from the side of the subacromial space of the tendon, is reasonable when the damage depth is more than 20% of the thickness of the tendon. When the tear is localized on the articular surface of the tendon, justification by suture is justified if the depth of damage exceeds 50%

THE CHAIN OF VALUE CREATION OF GAS COMPANIES IN THE CONDITIONS OF VERTICAL INTEGRATION ON THE EXAMPLE OF THE PRODUCTION SEGMENT This article focuses on the value chain in the gas industry using the example of Porter's model. the article describes the process of gas production, infrastructure, main and auxiliary activities of the gas industry.

CHARACTERS AS CONTENT OF CONSCIOUSNESS OF YOUTH The study interprets zone continuum social data gap. It is designed to 1. Select the desired information from the "media noise" information society 2. Describe the set of images describing Visual representations and comprehension (in such submissions, quite prosperous part of Russian youth, how students socio-humanitarian areas of Russian universities in the year 2017). Recorded nearly complete "reboot" shaped youth system. Overall youth international moral agenda could be considered formed. The findings are multiple and specific. For example, if the animals-cartoon characters 1990-2000's (like animal characters from the Soviet past”), is characterized by a positive connotation. For the heroes of the Internet, on the contrary, negative or neutral. The predominance of the heroes of the Internet in the category of "indefinite gender over images, entrenched in the popular consciousness through other channels. 2. to establish their relationship with for 6-12 years, changes in the system of images, filling Russian media. Material research is very relevant, as will serve as an adequate basis for specific projects within the framework of socio-humanitarian technology. Refers to the technologies used in modern Russia. The results of the research allow not only put and clarify new challenges for future research, but also, more importantly, they identify the installation, values, worldview themselves future socio-humanitarian technologists. Dramatically (compared to 2012 year) reduces the number of characters suffering from alcoholism or drug addiction. Attitude to alcohol and drugs in society becomes more neutral. In the year 2017 wave appears a large number of characters with a variety of "oderzhimostjami" (neuroses). And, basically, «neuroses» are related to some kind of "obsession". The study showed that fictional character with real images of media personalities and the objects surrounding the socio-cultural reality. The amazing feature of this connection is the blurring of the lines between objects of the invention and reality. Most-totally unexpectedly for the authors. Research methodology has the pedigree of "included" observation ethnographic methods. As a result, the material devoted to the results of the aggregation of several hundred of the most relevant characters and their intelligence. The study aims to: 1. identify changes or shifts in thinking about the world .2. to establish their relationship with for 6-12 years, changes in the system of images, filling Russian media. Material research is very relevant, as will serve as an adequate basis for specific projects within the framework of socio-humanitarian technology. Refers to the technologies used in modern Russia. The results of the research allow not only put and clarify new challenges for future research, but also, more importantly, they identify the installation, values, worldview themselves future socio-humanitarian technologists.

Russian Historian I. Ja. Froyanov The article is written on the eve of the 80th birthday of Igor Yakovlevich Froyanov, one of the most outstanding Russian historians. The author makes an attempt to show I.Y. Froyanov's life in the context of his key scientific achievements: his creation of a new concept of ancient history of Russia and the foundation on its base of a leading scientific school of thought in Russian history. The main and most significant works of the historian are analyzed in chrono-logical order, and thus the logic of the genesis of I.Y. Froyanov's views is traced. This process is considered in the context of the development of the historian's career, the author describes the main stages of his creative work and characteristic features of his works of different time.

ACCOUNTING (FINANCIAL) STATEMENTS AS AN INFORMATION BASE FOR ANALYSIS OF THE FINANCIAL STATE OF THE ORGANIZATION This article identifies and studies the areas of analysis of the financial position of an organization on the basis of accounting (financial) statements

DETECTION OF TECHNICAL ERRORS IN THE INFORMATION REAL ESTATE CADASTRE Currently in the real estate cadastre there is a large number of errors in information about real estate. The presence of errors in the Unified State Register of Real Estate or documents on the ownership of real estate objects is the basis for the suspension and subsequent refusal in the state cadastral registration and further registration of rights to real estate. In such a situation, the applicant must prove the violation of his rights.One of the fundamental characteristics of the Unified State Real Estate Register system is its orientation to interdepartmental interaction and data exchange with other information systems of federal and local executive and legislative authorities of the Russian Federation. As a result, if there are erroneous data in the real property cadastre data regarding the real estate object, such errors are automatically exported to other databases, and as a result they carry a string of multiple errors in the information of the real estate cadastre and various registers and cadastres. In his article, the author examines and cites examples of often encountered in practice technical mistakes in the management of the real estate cadastre.

THOUGHTS AND QUESTIONS ARISING UPON THE RECOGNITION OF THE BROADLY BIOACTIVE AND VERY WELL TOLERATED ANTISEPTIC NCHLOROTAURINE AS A HIGHLY USEFUL MEDICANT FOR PROPHYLAXIS AND THERAPY This report emerged from the experiences and observations of the authors who explored fundamental features of NCT and accounted for production and essential understanding of its realm of welcome properties. Nchlorotaurine (NCT) is an endogenous mild active chlorine compound, which can be synthesized chemically and applied topically as an effective anti infective and antiseptic to different body sites. Naturally, it is produced by activated human granulocytes and monocytes during the oxidative burst. Besides the typical broadspectrum microbicidal activity of chloramines against all kinds of microorganisms, it has antiinflammatory properties and is involved in termination of inflammation. Because of its high tolerability and absence of systemic adverse effects due to decay to ubiquitous taurine and chloride, it can be used in sensitive body regions, too, for instance the eye, body cavities and lower airways. The latter renders NCT inhalation a promising means for the prevention and treatment of viral pneumonia including SARSCoV2 (Covid-19), chronic bronchitis, and cystic fibrosis. Further clinical development is urgently needed to characterize the preventive and therapeutic effects in detail. Particularly the time of the present pandemic confirmed how difficult recognition and support of innovations frequently is.

Attitude of participants to mass competitions in orienteering "Russian azimuth - 2018" The article deals with the results of the study of the attitude of participants to the organization and conduct of mass sports competitions in orienteering "Russian azimut - 2018". It is revealed that the attitude of participants to this event is affected by the frequency of participation in it. Regular participation in mass competitions has a positive effect on the introduction to sports. Motives of participation of athletes in competitions, and also degree of satisfaction with their organization and carrying out are studied. The obtained results of the attitude of the participants of mass competitions are considered as an important element of feedback in the management of the sporting event.

Express evaluation of reproductive capacity of dogs in the conditions of the nursery In recent decades doctors of veterinary medicine have devoted particular attention to dogs and, in particular, to the questions of physiology and pathology of their reproduction. The result is the publication of a significant number of manuals and monographs devoted to the actual issues of diagnosis and treatment of small animal diseases. Little remains the problems of andrological pathology of dogs, while the requirements for quality and number of offspring in high-value breeds of dogs and, consequently, reproductive health dogs. An important direction in solving these issues is the holding of andrological dispensary, which allows to diagnose the form of impotence, to identify the causes, to develop medical and preventive measures. However, in the conditions of large nurseries to study a significant number of dogs in limited time, there is a need for an accelerated, but at the same time, objective assessment of reproductive capacity of males. Proceeding from this, the aim of the work was to validate the method developed by us for express evaluation of the reproductive capacity of dogs in the conditions of a particular nursery. We have developed an express assessment of the reproductive capacity of dogs, which involves conducting a general clinical trial of males, a survey of the genitourinary system, determining the manifestation of sexual reflexes and the withdrawal of spermograms. The obtained results of research were distributed on a scale: «G» (good) - pathological changes were not found, all indicators of homeostasis and spermograms within the norm. The pedigree can be used without restrictions; «S» (satisfactory) - slight deviations from the norm, which have a minor effect on the body and partly reduce the reproductive potential of the dog. The herb is allowed to reproduce with a restriction on the careful control of its reproductive use; «U» (unsatisfactory) - a pathological state of the body, hypotension or impotence. Breeding is not allowed. According to the results of the research, it was determined that express assessment of the reproductive capacity of the dogs makes it possible to carry out a quick and fairly objective assessment of the reproductive potential of a large number of dogs for a limited period, to identify diseased animals, to develop and implement the necessary preventive or curative measures. It was established that from the total number of evaluated dogs of the «Zvezdnoye schastye» nursery, 12 dogs (or 76%) were rated «good» and recommended for breeding, 4 - were «satisfactorily» (18%) and could be allowed to be restrained with careful control their reproductive use, 1 - «unsatisfactory» (6%) with the recommendation to carry out the treatment of concomitant pathologies and pass a repeat test in a month.

APPROACHES TO THE ASSESSMENT OF AGROTOURIST CAPACITY OF THE TERRITORY The present article is devoted to generalization of techniques of an assessment of agro tourist potential of development of rural, natural and informative tourism in municipal areas. Need of a complex assessment of agro tourist potential is proved. The concept of tourist potential, factors influencing its formation, and also assessment parameters is studied. Advantages of agro tourism from a position of social perception are considered. Evaluation stages of tourist and recreational potential and agro tourist appeal of the territory are presented. Use of the generalized technique allows to estimate objectively the agro tourist capacity of rural territories taking into account specific features of each region of the country.

GOVERNMENTAL POLICY IN REGIONAL BOOK-PUBLISHING DEVELOPMENT IN THE ALTAI KRAI Some results of the author’s analysis of influence Russian state policy that it has upon re-gional book-publishing system through Scientific and Consultative Council under the Governor of the Altai Krai 2010-2017 activity are outlined. The paper considers some peculiarities of thematic approach to forming a list of materials intended for publication. The author draws the mechanism of major book-publishing projects execution, gives a common portrait of the system of book business in the Russian region.

The innovative activity as an element of the military and economic preparations In the article there are given the results of analysis of the innovative activity as an element of the military and economic preparations of the United Kingdom. There are considered the main features and trends of this activity, including the pursuing public policy in a field of innovations; financing of R&D and development of organizational structures, ensuring realization of its, also arms procurement and orders in the UK.

Association of leptin gene polymorphisms with predisposition of cattle to ketosis Leptin is a hormone produced by adipocytes - cells of adipose tissue, involved in the regulation of eating behavior, affecting the reproductive function, as well as the growth and Constitution of animals. In certain physiological conditions in cows, intensive use of their own fat reserves leads to excessive appearance of volatile fatty acids in the blood, which, in turn, become «satiety signals» and lead to a reduction in feed consumption. At this point, the genetic characteristics of the animal associated with the regulation of metabolism, eating behavior, contributing to or preventing the possible development of ketosis become particularly important. The aim of the research is to determine the possible influence of the leptin locus genotype (y7f, a80v, R25C polymorphisms) on the frequency of ketosis in cattle. We have genotyped Holstein breeding bulls (PCR/RFLP) belonging to WWS (USA) based on the A80V, R25C, and Y7F loci of the leptin gene, which were evaluated by their daughters and «ketosis resistance coefficients» (Wellness trait index (WT$) ketosis) were determined with a high level of confidence. It was found that the group of breeding bulls with the AARRYY genotype is distinguished by a significantly higher average index of «daughters' resistance to ketosis» compared to the AARCYY and AVCCYY groups, which may indicate that the AARRYY genotype in breeding bulls is one of the genetic factors protecting their daughters from the development of ketosis. In addition, 150 Holstein cows were genotyped using the same loci, of which 50 had ketosis and 100 were healthy. In the group of healthy Holstein cows, compared with the group of animals with ketosis and hepatopathology, the AARCYY genotype was three times more common.

A case of Bureau-Barrie`re-type sporadic ulcerative-mutilating acropathy A rare clinical case of Bureau-Barrie`re-type sporadic ulcerative-mutilating acropathy is described.

Mechanism of conducting of social and political modernization in the regions of the country on the background of the Russian level of development (on the example of Republic of Komi) This article discusses general trends and tendencies of modernization processes in contemporary Russia. The author suggests a possible mechanism for social and political modernization in the Russian regions through the development of regional intelligence centers. Also in the dynamics of the expectations of Russians on the development of major problem areas of socio-political system.

POSSIBLE STEPS OF RUSSIA IN INTERACTION WITH CHINA TO ENSURE SECURITY IN THE SCO AREA The article analyzes the interconnection of drug trafficking and international terrorism. Their impact on security and stability of the Central Asian region is also assessed. The author considers possible steps of Russia in collaboration with its partners by the Shanghai Cooperation Organization to be made in the interests of national and regional security.

The Commandment of John Chrysostomon Church Law in East Slavic Tradition (on the issue of new texts in the monastic libraries) The article continues the study of the pseudepigraphic Commandment of John Chrysostom on Church Law, known in Serbian Trebniks of the 14th-15th centuries,as well as in Bulgarian and Moldavian manuscripts of the 15th-16th centuries. Forthe first time, the characteristics of four East Slavic editions of the Commandmentare given. Three of them date from the beginning of the 15th century. and are part ofstable collections: collections of the “Arkhangelsk” type, the Myasnikov edition of theKormchaja, the Kiril-Belozerosky edition of the Nomocanon of John the Faster and reflect the process of creating new types of canonical collections. Only in the collectionsof the “Arkhangelsk” type is the Commandment in its entirety, including the chapter onthe Bogomils. The text of the Commandment was subjected to the greatest revision in the“Barsov” edition, which is found in the composition of the “nomocanons” addressed topriests. These collections do not have a stable composition, although they contain manymatching blocks. A study of the “Barsov” edition shows that the text is found not only inthe tradition of monasteries, but also among collections addressed to priests.

Flux-cored wire for surfacing corrosion-resistant and wear-resistant steel The influence of boron carbide on the structure of a metal, deposited by a high-chromium flux-cored wire, is studied to improve the operational properties of corrosion-resistant coatings in tribological couplings. It is determined, that a martensite matrix with reduced fragments of structure, formed as a result of the separation of dispersed boride phases, increases the hardness and wear resistance of the weld metal.

THE PSYCHOLOGY IS RIGHT The psychological theory of the right is directed to that the kind psychological beginnings of the person improved his aspiration to make the right the assistant to people in their fight for freedom and justice. The author proves that the modern school of the psychological theory of the right should put emphasis on a combination of the objective and subjective beginning in the right, interaction and interpenetration of his official and intuitive substances, on legal averaging with prevalence of a positive law as the basic.

Ecclesiological and eschatological aspects of taxation in the works of the Great Cappadocians The article is devoted to the cornerstone concept of the soteriology of the Eastern Church - deification according to the works of the Great Cappadocians. The great Fathers of the Church answer the question, which does not lose its relevance in all eras of the Christian Church - from the day of Pentecost to the present time - how is salvation (a synonym for deification) realized in practical life through the sacraments of the Church and the ascetic life? In addition, the Great Luminaries are trying to reveal the secret of the future age, making attempts to show what awaits a person when God will be "all in all" (1 Cor 15:23).