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17901
[ "Hirsutism", "markedly", "improved", "in", "all", "women", "during", "the", "treatment", "(", "Ferriman-Gallwey", "score", "after", "1", "year", ":", "4.1", "+/-", "0.5", "versus", "14.1", "+/-", "0.9", ")", "." ]
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17902
[ "A", "reduction", "of", "serum", "androgens", "was", "found", ",", "whereas", "no", "change", "was", "observed", "in", "either", "basal", "or", "GnRH-stimulated", "gonadotropins", "or", "in", "the", "cortisol", "and", "17", "alpha-hydroxyprogesterone", "response", "to", "ACTH", "." ]
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17903
[ "Cycles", "remained", "ovulatory", "." ]
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17904
[ "Before", "treatment", ",", "the", "number", "of", "androgen", "receptors", "was", "higher", "in", "the", "luteal", "than", "in", "the", "follicular", "phase", "." ]
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17905
[ "This", "rhythmic", "differentiation", "disappeared", "after", "the", "patients", "had", "been", "given", "the", "antiandrogen", "drug", "." ]
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17906
[ "CONCLUSIONS", ":", "Flutamide", "is", "effective", "in", "the", "treatment", "of", "hirsutism", "but", "requires", "constant", "surveillance", "of", "liver", "function", "." ]
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17907
[ "Androgen", "receptor", "blockade", "might", "be", "potentiated", "by", "a", "reduction", "of", "serum", "androgens", "." ]
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17908
[ "Flutamide", "affects", "androgen", "receptor", "behavior", "during", "the", "menstrual", "cycle", "." ]
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17909
[ "The", "meaning", "of", "this", "finding", "remains", "to", "be", "elucidated", "." ]
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17910
[ "Constitutive", "expression", "of", "HIV-1", "tat", "protein", "in", "human", "Jurkat", "T", "cells", "using", "a", "BK", "virus", "vector", "." ]
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17911
[ "The", "production", "and", "characterization", "of", "Jurkat", "cell", "lines", "that", "constitutively", "express", "functional", "human", "immune", "deficiency", "virus", "type", "1", "(", "HIV-1", ")", "tat", "protein", ",", "using", "a", "BK", "virus", "plasmid", "expression", "vector", "and", "HIV-1", "tat", "cDNA", ",", "is", "described", "." ]
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17912
[ "An", "increased", "growth", "rate", "of", "these", "Jurkat-tat", "cell", "lines", "as", "compared", "with", "control", "cell", "lines", "was", "observed", "." ]
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17913
[ "A", "PEBP2", "alpha/AML-1-related", "factor", "increases", "osteocalcin", "promoter", "activity", "through", "its", "binding", "to", "an", "osteoblast-specific", "cis-acting", "element", "." ]
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17914
[ "To", "identify", "osteoblast-specific", "cis-acting", "elements", "and", "trans-acting", "factors", ",", "we", "initiated", "an", "analysis", "of", "the", "promoter", "of", "a", "mouse", "osteocalcin", "gene", ",", "an", "osteoblast-specific", "gene", "." ]
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17915
[ "In", "this", "promoter", ",", "we", "identified", "two", "osteoblast-specific", "cis-acting", "elements", "(", "Ducy", ",", "P.and", "Karsenty", ",", "G.", "(", "1995", ")", "Mol.Cell.Biol.15", ",", "1858-1869", ")", "." ]
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17916
[ "The", "sequence", "of", "one", "of", "these", "elements", ",", "OSE2", ",", "is", "identical", "to", "the", "DNA-binding", "site", "of", "the", "PEBP2", "alpha/AML-1", "transcription", "factors", ",", "the", "mammalian", "homologues", "of", "the", "Drosophila", "Runt", "protein", "." ]
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17917
[ "Here", "we", "show", ",", "using", "nuclear", "extracts", ",", "recombinant", "protein", ",", "and", "a", "specific", "antiserum", "against", "AML-1", "proteins", "in", "DNA-binding", "assays", ",", "that", "one", "member", "of", "this", "family", ",", "AML-1B", ",", "binds", "specifically", "to", "OSE2", "and", "is", "immunologically", "related", "to", "OSF2", ",", "the", "factor", "present", "in", "osteoblast", "nuclear", "extracts", "that", "binds", "to", "OSE2", "." ]
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17918
[ "By", "DNA", "cotransfection", "experiments", ",", "we", "also", "demonstrate", "that", "AML-1B", "can", "increase", "the", "activity", "of", "a", "short", "osteocalcin", "promoter", "through", "its", "binding", "to", "OSE2", "." ]
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17919
[ "Lastly", ",", "the", "different", "mobilities", "of", "osteoblast", "nuclear", "extract-DNA", "complexes", "compared", "with", "T-cell", "nuclear", "extract-DNA", "complexes", ",", "along", "with", "the", "inability", "of", "OSF2", "to", "be", "upregulated", "by", "retinoic", "acid", ",", "unlike", "the", "other", "PEBP2", "alpha", "factors", ",", "suggest", "that", "OSF2", "is", "a", "new", "member", "of", "this", "family", "of", "transcription", "factors", "." ]
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17920
[ "Thus", ",", "this", "study", "demonstrates", "that", "AML-1B", "can", "increase", "gene", "expression", "of", "an", "osteoblast-specific", "gene", "through", "its", "binding", "to", "an", "osteoblast-specific", "cis-acting", "element", "and", "presents", "evidence", "that", "OSF2", "is", "a", "member", "of", "the", "PEBP2", "alpha/AML-1", "family", "of", "transcription", "factors", "." ]
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17921
[ "Initiation", "binding", "repressor", ",", "a", "factor", "that", "binds", "to", "the", "transcription", "initiation", "site", "of", "the", "histone", "h5", "gene", ",", "is", "a", "glycosylated", "member", "of", "a", "family", "of", "cell", "growth", "regulators", "[", "corrected", "]", "[", "published", "erratum", "appears", "in", "Mol", "Cell", "Biol", "1996", "Feb", ";", "16", "(", "2", ")", ":", "735", "]" ]
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17922
[ "Initiation", "binding", "repressor", "[", "corrected", "]", "(", "IBR", ")", "is", "a", "chicken", "erythrocyte", "factor", "(", "apparent", "molecular", "mass", ",", "70", "to", "73", "kDa", ")", "that", "binds", "to", "the", "sequences", "spanning", "the", "transcription", "initiation", "site", "of", "the", "histone", "h5", "gene", ",", "repressing", "its", "transcription", "." ]
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17923
[ "A", "variety", "of", "other", "cells", ",", "including", "transformed", "erythroid", "precursors", ",", "do", "not", "have", "IBR", "but", "a", "factor", "referred", "to", "as", "IBF", "(", "68", "to", "70", "kDa", ")", "that", "recognizes", "the", "same", "IBR", "sites", "." ]
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17924
[ "We", "have", "cloned", "the", "IBR", "cDNA", "and", "studied", "the", "relationship", "of", "IBR", "and", "IBF", "." ]
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17925
[ "IBR", "is", "a", "503-amino-acid-long", "acidic", "protein", "which", "is", "99.0", "%", "identical", "to", "the", "recently", "reported", "human", "NRF-1/alpha-Pal", "factor", "and", "highly", "related", "to", "the", "invertebrate", "transcription", "factors", "P3A2", "and", "erected", "wing", "gene", "product", "(", "EWG", ")", "." ]
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17926
[ "We", "present", "evidence", "that", "IBR", "and", "IBF", "are", "most", "likely", "identical", "proteins", ",", "differing", "in", "their", "degree", "of", "glycosylation", "." ]
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17927
[ "We", "have", "analyzed", "several", "molecular", "aspects", "of", "IBR/F", "and", "shown", "that", "the", "factor", "associates", "as", "stable", "homodimers", "and", "that", "the", "dimer", "is", "the", "relevant", "DNA-binding", "species", "." ]
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17928
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17929
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17930
[ "A", "survey", "of", "genes", "potentially", "regulated", "by", "this", "family", "of", "factors", "primarily", "revealed", "genes", "involved", "in", "growth-related", "metabolism", "." ]
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17931
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17932
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17933
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17934
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17935
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17936
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17937
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17938
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17939
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17940
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17941
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17942
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17943
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17944
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17945
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17946
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17947
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17948
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17949
[ "Flow", "cytometry", "showed", "that", "L-selectin", "was", "expressed", "on", "fresh", "ATL", "cells", "along", "with", "other", "activation", "antigens", "." ]
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17950
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17951
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17952
[ "Intravenous", "injection", "of", "a", "rat", "T-cell", "line", "that", "overexpresses", "L-selectin", "showed", "increased", "organ", "infiltration", "." ]
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17953
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17954
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17955
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17956
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17957
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17958
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17959
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17960
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17961
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17962
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17963
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17964
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17965
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17966
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17967
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17968
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17969
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17970
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17971
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17972
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17973
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17974
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17975
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17976
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17977
[ "(", "ABSTRACT", "TRUNCATED", "AT", "250", "WORDS", ")" ]
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17978
[ "Characterization", "of", "5", "'", "end", "of", "human", "thromboxane", "receptor", "gene", "." ]
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17979
[ "Organizational", "analysis", "and", "mapping", "of", "protein", "kinase", "C", "--", "responsive", "elements", "regulating", "expression", "in", "platelets", "." ]
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17980
[ "Platelet", "thromboxane", "receptors", "are", "acutely", "and", "reversibly", "upregulated", "after", "acute", "myocardial", "infarction", "." ]
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17981
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17982
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17983
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17984
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17985
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17986
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17987
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17988
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17989
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17990
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17991
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17992
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